Compile Data Set for Download or QSAR

Found 232 hits with Last Name = 'schwed' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50392759 (CHEMBL2151157) Show SMILES CC(C)N1CCCN(CC1)C(=O)C1CCN(CC1)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C20H29F3N4O/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23/h4-5,14-16H,3,6-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50535225 (CHEMBL4516622) Show SMILES C[C@@H]1CCCN1[C@H]1C[C@@H](C1)c1ccc(cc1)-c1ccc(cc1)C#N |r,wU:8.11,1.0,wD:6.6,(34.83,-7.94,;35.15,-9.44,;34.11,-10.59,;34.88,-11.92,;36.39,-11.6,;36.55,-10.07,;37.88,-9.3,;39.37,-9.7,;39.77,-8.21,;38.28,-7.81,;41.1,-7.45,;41.1,-5.9,;42.43,-5.13,;43.77,-5.9,;43.77,-7.45,;42.43,-8.22,;45.09,-5.12,;46.43,-5.89,;47.76,-5.12,;47.75,-3.58,;46.41,-2.81,;45.08,-3.59,;49.08,-2.8,;50.41,-2.03,)| Show InChI InChI=1S/C22H24N2/c1-16-3-2-12-24(16)22-13-21(14-22)20-10-8-19(9-11-20)18-6-4-17(15-23)5-7-18/h4-11,16,21-22H,2-3,12-14H2,1H3/t16-,21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human H3R				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013722 (CHEMBL3264546) Show SMILES CCOC(=O)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C23H36N2O3/c1-2-27-23(26)21-11-16-25(17-12-21)19-20-7-9-22(10-8-20)28-18-6-15-24-13-4-3-5-14-24/h7-10,21H,2-6,11-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50001752 (CHEMBL3238445) Show SMILES Cc1nnc(-c2cccnc2)n1-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C22H27N5O/c1-18-24-25-22(19-7-5-12-23-17-19)27(18)20-8-10-21(11-9-20)28-16-6-15-26-13-3-2-4-14-26/h5,7-12,17H,2-4,6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
United Arab Emirates University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human H3 receptor expressed in HEK-293 cell membrane after 90 mins by liquid scintillation counting ...				Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50158595 ((4'-(3-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)propox...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 |r| Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human H3R expressed in rat C6 cells				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013718 (CHEMBL3264547) Show SMILES Cc1nnc(o1)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C23H34N4O2/c1-19-24-25-23(29-19)21-10-15-27(16-11-21)18-20-6-8-22(9-7-20)28-17-5-14-26-12-3-2-4-13-26/h6-9,21H,2-5,10-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	0.479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Binding affinity to rat histamine H3 receptor				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50375373 (CHEMBL129306) Show SMILES OC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H32N2O2/c23-19-9-14-22(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-21-11-2-1-3-12-21/h5-8,19,23H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Binding affinity to rat histamine H3 receptor				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Cc1nc2cccc(c2c(=O)n1-c1ccc(OCCCN2CCCC2)cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N3O2/c1-16-27-20-7-4-6-19(23(24,25)26)21(20)22(30)29(16)17-8-10-18(11-9-17)31-15-5-14-28-12-2-3-13-28/h4,6-11H,2-3,5,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50375375 (CHEMBL259482) Show SMILES OCC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C21H34N2O2/c24-18-20-9-14-23(15-10-20)17-19-5-7-21(8-6-19)25-16-4-13-22-11-2-1-3-12-22/h5-8,20,24H,1-4,9-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50375373 (CHEMBL129306) Show SMILES OC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H32N2O2/c23-19-9-14-22(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-21-11-2-1-3-12-21/h5-8,19,23H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.741	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278496 (1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidin-4...) Show SMILES CS(=O)(=O)OC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C21H34N2O4S/c1-28(24,25)27-21-10-15-23(16-11-21)18-19-6-8-20(9-7-19)26-17-5-14-22-12-3-2-4-13-22/h6-9,21H,2-5,10-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278496 (1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidin-4...) Show SMILES CS(=O)(=O)OC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C21H34N2O4S/c1-28(24,25)27-21-10-15-23(16-11-21)18-19-6-8-20(9-7-19)26-17-5-14-22-12-3-2-4-13-22/h6-9,21H,2-5,10-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50001751 (CHEMBL3238444) Show SMILES Cc1nnc(C)n1-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H26N4O/c1-15-19-20-16(2)22(15)17-7-9-18(10-8-17)23-14-6-13-21-11-4-3-5-12-21/h7-10H,3-6,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
United Arab Emirates University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human H3 receptor expressed in HEK-293 cell membrane after 90 mins by liquid scintillation counting ...				Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013719 (CHEMBL129785) Show SMILES C(COc1ccc(CN2CCc3ccccc3C2)cc1)CN1CCCCC1 Show InChI InChI=1S/C24H32N2O/c1-4-14-25(15-5-1)16-6-18-27-24-11-9-21(10-12-24)19-26-17-13-22-7-2-3-8-23(22)20-26/h2-3,7-12H,1,4-6,13-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50533199 (CHEMBL4527011) Show SMILES [H][C@]12CCN(c3ccc(cc3)-c3ccc(cc3)-n3ncccc3=O)[C@@]1([H])CN(C)C2 |r| Show InChI InChI=1S/C23H24N4O/c1-25-15-19-12-14-26(22(19)16-25)20-8-4-17(5-9-20)18-6-10-21(11-7-18)27-23(28)3-2-13-24-27/h2-11,13,19,22H,12,14-16H2,1H3/t19-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at human H3R expressed in rat C6 cells incubated for 20 mins by [35S]GTPgammaS binding assay				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013723 (CHEMBL3264545) Show SMILES C(COc1ccc(CN2CCC3(CC2)OCCO3)cc1)CN1CCCCC1 Show InChI InChI=1S/C22H34N2O3/c1-2-11-23(12-3-1)13-4-16-25-21-7-5-20(6-8-21)19-24-14-9-22(10-15-24)26-17-18-27-22/h5-8H,1-4,9-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013724 (CHEMBL3264544) Show SMILES O=C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H30N2O2/c23-19-9-14-22(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-21-11-2-1-3-12-21/h5-8H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013715 (CHEMBL3264550) Show SMILES CCNC(=O)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C23H37N3O2/c1-2-24-23(27)21-11-16-26(17-12-21)19-20-7-9-22(10-8-20)28-18-6-15-25-13-4-3-5-14-25/h7-10,21H,2-6,11-19H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013719 (CHEMBL129785) Show SMILES C(COc1ccc(CN2CCc3ccccc3C2)cc1)CN1CCCCC1 Show InChI InChI=1S/C24H32N2O/c1-4-14-25(15-5-1)16-6-18-27-24-11-9-21(10-12-24)19-26-17-13-22-7-2-3-8-23(22)20-26/h2-3,7-12H,1,4-6,13-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50426502 (Bodilisant | CHEMBL2323582) Show SMILES CC1=CC(C)=[N+]2C1=C(c1c(C)cc(C)n1[B-]2(F)F)c1ccc(OCCCN2CCCCC2)cc1 |c:4,t:1,7| Show InChI InChI=1S/C27H34BF2N3O/c1-19-17-21(3)32-26(19)25(27-20(2)18-22(4)33(27)28(32,29)30)23-9-11-24(12-10-23)34-16-8-15-31-13-6-5-7-14-31/h9-12,17-18H,5-8,13-16H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK-293 cells				ACS Med Chem Lett 4: 269-73 (2013) Article DOI: 10.1021/ml300383n BindingDB Entry DOI: 10.7270/Q2N87C3T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026359 (CHEMBL3331152) Show SMILES Cc1cn(Cc2ccc(OCCCN3CCCCC3)cc2)c(=O)[nH]c1=O Show InChI InChI=1S/C20H27N3O3/c1-16-14-23(20(25)21-19(16)24)15-17-6-8-18(9-7-17)26-13-5-12-22-10-3-2-4-11-22/h6-9,14H,2-5,10-13,15H2,1H3,(H,21,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026367 (CHEMBL3331144) Show SMILES O=C(c1ccccc1)n1c(=O)ccn(Cc2ccc(OCCCN3CCCCC3)cc2)c1=O Show InChI InChI=1S/C26H29N3O4/c30-24-14-18-28(26(32)29(24)25(31)22-8-3-1-4-9-22)20-21-10-12-23(13-11-21)33-19-7-17-27-15-5-2-6-16-27/h1,3-4,8-14,18H,2,5-7,15-17,19-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021553 (CHEMBL3290570) Show SMILES CN1CCN(CC1)c1ncnc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H16ClN5/c1-19-6-8-20(9-7-19)14-17-10-16-13(18-14)11-2-4-12(15)5-3-11/h2-5,10H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor after 45 mins by scintillation counting analysis				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
United Arab Emirates University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human H3 receptor expressed in HEK-293 cell membrane after 90 mins by liquid scintillation counting ...				Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013716 (CHEMBL3264549) Show SMILES O=C(NCC#C)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C24H35N3O2/c1-2-13-25-24(28)22-11-17-27(18-12-22)20-21-7-9-23(10-8-21)29-19-6-16-26-14-4-3-5-15-26/h1,7-10,22H,3-6,11-20H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant full length H3R expressed in HEK293 cell membranes incubated for 90 mins by liqui...				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026360 (CHEMBL3331151) Show SMILES O=c1ccn(Cc2ccc(OCCCN3CCCCC3)cc2)c(=O)[nH]1 Show InChI InChI=1S/C19H25N3O3/c23-18-9-13-22(19(24)20-18)15-16-5-7-17(8-6-16)25-14-4-12-21-10-2-1-3-11-21/h5-9,13H,1-4,10-12,14-15H2,(H,20,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50013717 (CHEMBL3264548) Show SMILES OC(=O)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C21H32N2O3/c24-21(25)19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)26-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50394646 (CHEMBL2164608) Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCn1cc2ccccc2c1C#N Show InChI InChI=1S/C30H26N2O4/c1-35-29-19-22(7-6-11-23-8-2-3-9-24(23)14-16-30(33)34)13-15-28(29)36-18-17-32-21-25-10-4-5-12-26(25)27(32)20-31/h2-6,8-16,19,21H,7,17-18H2,1H3,(H,33,34)/b11-6+,16-14+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta counting				ACS Med Chem Lett 3: 774-779 (2012) Article DOI: 10.1021/ml300191g BindingDB Entry DOI: 10.7270/Q2DZ09D3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50535226 (CHEMBL4445028) Show SMILES OC(=O)C(O)=O.C(CCCN1CCCCCC1)CCOc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C24H33NO/c1-2-9-18-25(17-8-1)19-10-3-4-11-20-26-24-16-12-15-23(21-24)22-13-6-5-7-14-22/h5-7,12-16,21H,1-4,8-11,17-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant full length H3R expressed in HEK293 cell membranes incubated for 90 mins by liqui...				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026358 (CHEMBL3331153) Show SMILES Cc1c(C)c(=O)[nH]c(=O)n1Cc1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C21H29N3O3/c1-16-17(2)24(21(26)22-20(16)25)15-18-7-9-19(10-8-18)27-14-6-13-23-11-4-3-5-12-23/h7-10H,3-6,11-15H2,1-2H3,(H,22,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50394647 (CHEMBL2164610) Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C27H25N3O8/c1-37-26-17-19(5-4-8-20-6-2-3-7-21(20)10-14-27(31)32)9-13-25(26)38-16-15-28-23-12-11-22(29(33)34)18-24(23)30(35)36/h2-4,6-14,17-18,28H,5,15-16H2,1H3,(H,31,32)/b8-4+,14-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	23.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta counting				ACS Med Chem Lett 3: 774-779 (2012) Article DOI: 10.1021/ml300191g BindingDB Entry DOI: 10.7270/Q2DZ09D3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50535224 (CHEMBL4540849) Show SMILES OC(=O)C(O)=O.C(CCOc1ccc(cc1)-c1ccccc1)CCN1CCCCC1 Show InChI InChI=1S/C22H29NO/c1-4-10-20(11-5-1)21-12-14-22(15-13-21)24-19-9-3-8-18-23-16-6-2-7-17-23/h1,4-5,10-15H,2-3,6-9,16-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant full length H3R expressed in HEK293 cell membranes incubated for 90 mins by liqui...				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026355 (CHEMBL3331157) Show SMILES O=c1cccnn1-c1ccc2nc(sc2c1)N1CC[C@H](C1)N1CCCCC1 |r| Show InChI InChI=1S/C20H23N5OS/c26-19-5-4-9-21-25(19)15-6-7-17-18(13-15)27-20(22-17)24-12-8-16(14-24)23-10-2-1-3-11-23/h4-7,9,13,16H,1-3,8,10-12,14H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	<25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50394645 (CHEMBL2164609) Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(=O)NS(=O)(=O)c2cccs2)ccc1OCCn1cc2ccccc2c1C#N Show InChI InChI=1S/C34H29N3O5S2/c1-41-32-22-25(15-17-31(32)42-20-19-37-24-28-11-4-5-13-29(28)30(37)23-35)8-6-12-26-9-2-3-10-27(26)16-18-33(38)36-44(39,40)34-14-7-21-43-34/h2-7,9-18,21-22,24H,8,19-20H2,1H3,(H,36,38)/b12-6+,18-16+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta counting				ACS Med Chem Lett 3: 774-779 (2012) Article DOI: 10.1021/ml300191g BindingDB Entry DOI: 10.7270/Q2DZ09D3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026357 (CHEMBL3331154) Show SMILES O=c1cc[nH]c(=O)n1Cc1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C19H25N3O3/c23-18-9-10-20-19(24)22(18)15-16-5-7-17(8-6-16)25-14-4-13-21-11-2-1-3-12-21/h5-10H,1-4,11-15H2,(H,20,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026366 (CHEMBL3331145) Show SMILES Cc1cn(Cc2ccc(OCCCN3CCCCC3)cc2)c(=O)n(C(=O)c2ccccc2)c1=O Show InChI InChI=1S/C27H31N3O4/c1-21-19-29(27(33)30(25(21)31)26(32)23-9-4-2-5-10-23)20-22-11-13-24(14-12-22)34-18-8-17-28-15-6-3-7-16-28/h2,4-5,9-14,19H,3,6-8,15-18,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50535223 (CHEMBL4586133) Show SMILES OC(=O)C(O)=O.C(CCOc1ccc(cc1)-c1ccccc1)CCN1CCCCCC1 Show InChI InChI=1S/C23H31NO/c1-2-8-18-24(17-7-1)19-9-4-10-20-25-23-15-13-22(14-16-23)21-11-5-3-6-12-21/h3,5-6,11-16H,1-2,4,7-10,17-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant full length H3R expressed in HEK293 cell membranes incubated for 90 mins by liqui...				Bioorg Med Chem 25: 5341-5354 (2017) Article DOI: 10.1016/j.bmc.2017.07.058 BindingDB Entry DOI: 10.7270/Q29W0K0D
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026365 (CHEMBL3331146) Show SMILES Cc1c(C)c(=O)n(C(=O)c2ccccc2)c(=O)n1Cc1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H33N3O4/c1-21-22(2)30(28(34)31(26(21)32)27(33)24-10-5-3-6-11-24)20-23-12-14-25(15-13-23)35-19-9-18-29-16-7-4-8-17-29/h3,5-6,10-15H,4,7-9,16-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026362 (CHEMBL3331149) Show SMILES Cc1c(C)c(=O)n(Cc2ccc(OCCCN3CCCCC3)cc2)c(=O)n1C(=O)OC(C)(C)C Show InChI InChI=1S/C26H37N3O5/c1-19-20(2)29(25(32)34-26(3,4)5)24(31)28(23(19)30)18-21-10-12-22(13-11-21)33-17-9-16-27-14-7-6-8-15-27/h10-13H,6-9,14-18H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50001753 (CHEMBL3238446) Show SMILES C[C@H](NCc1ccc(OCCCN2CCCCC2)cc1)C(N)=O |r| Show InChI InChI=1S/C18H29N3O2/c1-15(18(19)22)20-14-16-6-8-17(9-7-16)23-13-5-12-21-10-3-2-4-11-21/h6-9,15,20H,2-5,10-14H2,1H3,(H2,19,22)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
United Arab Emirates University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human H3 receptor expressed in HEK-293 cell membrane after 90 mins by liquid scintillation counting ...				Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM27213 (4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...) Show SMILES O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK-293 cells				ACS Med Chem Lett 4: 269-73 (2013) Article DOI: 10.1021/ml300383n BindingDB Entry DOI: 10.7270/Q2N87C3T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026363 (CHEMBL3331148) Show SMILES Cc1cn(C(=O)OC(C)(C)C)c(=O)n(Cc2ccc(OCCCN3CCCCC3)cc2)c1=O Show InChI InChI=1S/C25H35N3O5/c1-19-17-28(24(31)33-25(2,3)4)23(30)27(22(19)29)18-20-9-11-21(12-10-20)32-16-8-15-26-13-6-5-7-14-26/h9-12,17H,5-8,13-16,18H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50026364 (CHEMBL3331147) Show SMILES CC(C)(C)OC(=O)n1ccc(=O)n(Cc2ccc(OCCCN3CCCCC3)cc2)c1=O Show InChI InChI=1S/C24H33N3O5/c1-24(2,3)32-23(30)26-16-12-21(28)27(22(26)29)18-19-8-10-20(11-9-19)31-17-7-15-25-13-5-4-6-14-25/h8-12,16H,4-7,13-15,17-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 86: 578-88 (2014) Article DOI: 10.1016/j.ejmech.2014.09.011 BindingDB Entry DOI: 10.7270/Q2222WCC
					More data for this Ligand-Target Pair

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