Compile Data Set for Download or QSAR

Found 179 hits with Last Name = 'sechler' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179206 (3-trifluoromethyl-N-(6,7-dimethoxy-2,4-dihydroinde...) Show SMILES COc1cc2Cc3c(Nc4cccc(c4)C(F)(F)F)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H16F3N3O2/c1-26-15-7-10-6-14-17(13(10)9-16(15)27-2)24-25-18(14)23-12-5-3-4-11(8-12)19(20,21)22/h3-5,7-9H,6H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179212 (3-chloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(Cl)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16ClN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179207 (3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179207 (3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179211 (3-bromo-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]p...) Show SMILES COc1cc2Cc3c(Nc4cccc(Br)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16BrN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179209 ((6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-y...) Show SMILES COc1cc2Cc3c(Nc4ccccc4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H17N3O2/c1-22-15-9-11-8-14-17(13(11)10-16(15)23-2)20-21-18(14)19-12-6-4-3-5-7-12/h3-7,9-10H,8H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179209 ((6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-y...) Show SMILES COc1cc2Cc3c(Nc4ccccc4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H17N3O2/c1-22-15-9-11-8-14-17(13(11)10-16(15)23-2)20-21-18(14)19-12-6-4-3-5-7-12/h3-7,9-10H,8H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179210 ((7-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)ph...) Show SMILES COc1ccc2Cc3c(Nc4ccccc4)[nH]nc3-c2c1 Show InChI InChI=1S/C17H15N3O/c1-21-13-8-7-11-9-15-16(14(11)10-13)19-20-17(15)18-12-5-3-2-4-6-12/h2-8,10H,9H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179204 (3-methoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c...) Show SMILES COc1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1 Show InChI InChI=1S/C19H19N3O3/c1-23-13-6-4-5-12(9-13)20-19-15-7-11-8-16(24-2)17(25-3)10-14(11)18(15)21-22-19/h4-6,8-10H,7H2,1-3H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179204 (3-methoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c...) Show SMILES COc1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1 Show InChI InChI=1S/C19H19N3O3/c1-23-13-6-4-5-12(9-13)20-19-15-7-11-8-16(24-2)17(25-3)10-14(11)18(15)21-22-19/h4-6,8-10H,7H2,1-3H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179216 (3-carbomethoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[...) Show SMILES COC(=O)c1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1 Show InChI InChI=1S/C20H19N3O4/c1-25-16-9-12-8-15-18(14(12)10-17(16)26-2)22-23-19(15)21-13-6-4-5-11(7-13)20(24)27-3/h4-7,9-10H,8H2,1-3H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179216 (3-carbomethoxy-N-(6,7-dimethoxy-2,4-dihydroindeno[...) Show SMILES COC(=O)c1cccc(Nc2[nH]nc-3c2Cc2cc(OC)c(OC)cc-32)c1 Show InChI InChI=1S/C20H19N3O4/c1-25-16-9-12-8-15-18(14(12)10-17(16)26-2)22-23-19(15)21-13-6-4-5-11(7-13)20(24)27-3/h4-7,9-10H,8H2,1-3H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179217 (3-methyl-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(C)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H19N3O2/c1-11-5-4-6-13(7-11)20-19-15-8-12-9-16(23-2)17(24-3)10-14(12)18(15)21-22-19/h4-7,9-10H,8H2,1-3H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179208 (6,7-dimethoxy-3-phenyl-1,4-dihydroindeno[1,2-c]pyr...) Show SMILES COc1cc2Cc3c([nH]nc3-c3ccccc3)-c2cc1OC Show InChI InChI=1S/C18H16N2O2/c1-21-15-9-12-8-14-17(11-6-4-3-5-7-11)19-20-18(14)13(12)10-16(15)22-2/h3-7,9-10H,8H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179208 (6,7-dimethoxy-3-phenyl-1,4-dihydroindeno[1,2-c]pyr...) Show SMILES COc1cc2Cc3c([nH]nc3-c3ccccc3)-c2cc1OC Show InChI InChI=1S/C18H16N2O2/c1-21-15-9-12-8-14-17(11-6-4-3-5-7-11)19-20-18(14)13(12)10-16(15)22-2/h3-7,9-10H,8H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179210 ((7-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)ph...) Show SMILES COc1ccc2Cc3c(Nc4ccccc4)[nH]nc3-c2c1 Show InChI InChI=1S/C17H15N3O/c1-21-13-8-7-11-9-15-16(14(11)10-13)19-20-17(15)18-12-5-3-2-4-6-12/h2-8,10H,9H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50179207 (3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against c-ABL				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179211 (3-bromo-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]p...) Show SMILES COc1cc2Cc3c(Nc4cccc(Br)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16BrN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179206 (3-trifluoromethyl-N-(6,7-dimethoxy-2,4-dihydroinde...) Show SMILES COc1cc2Cc3c(Nc4cccc(c4)C(F)(F)F)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H16F3N3O2/c1-26-15-7-10-6-14-17(13(10)9-16(15)27-2)24-25-18(14)23-12-5-3-4-11(8-12)19(20,21)22/h3-5,7-9H,6H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50179207 (3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRalpha				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179213 ((5-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)ph...) Show SMILES COc1cccc-2c1Cc1c(Nc3ccccc3)[nH]nc-21 Show InChI InChI=1S/C17H15N3O/c1-21-15-9-5-8-12-13(15)10-14-16(12)19-20-17(14)18-11-6-3-2-4-7-11/h2-9H,10H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6417 (4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C19H20ClN5O/c20-15-4-3-5-16(9-15)24-19-13-22-12-18(25-19)14-8-17(11-21-10-14)23-6-1-2-7-26/h3-5,8-13,23,26H,1-2,6-7H2,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6421 (N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCn3cncn3)c2)c1 Show InChI InChI=1S/C20H19ClN8/c21-16-3-1-4-17(8-16)27-20-12-23-11-19(28-20)15-7-18(10-22-9-15)25-5-2-6-29-14-24-13-26-29/h1,3-4,7-14,25H,2,5-6H2,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6419 (N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3cccnc3)c2)c1 Show InChI InChI=1S/C23H21ClN6/c24-19-6-1-7-20(11-19)29-23-16-27-15-22(30-23)18-10-21(14-26-13-18)28-9-3-5-17-4-2-8-25-12-17/h1-2,4,6-8,10-16,28H,3,5,9H2,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6391 ((3-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamin...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3ccncc3)c2)c1 Show InChI InChI=1S/C23H21ClN6/c24-19-4-1-5-20(12-19)29-23-16-27-15-22(30-23)18-11-21(14-26-13-18)28-8-2-3-17-6-9-25-10-7-17/h1,4-7,9-16,28H,2-3,8H2,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6420 (N-(3-Chlorophenyl)-6-[5-[[3-(1H-pyrazol-1-yl)propy...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCn3cccn3)c2)c1 Show InChI InChI=1S/C21H20ClN7/c22-17-4-1-5-18(11-17)27-21-15-24-14-20(28-21)16-10-19(13-23-12-16)25-6-2-8-29-9-3-7-26-29/h1,3-5,7,9-15,25H,2,6,8H2,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50179207 (3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against LCK				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6418 (N-(3-chlorophenyl)-6-(5-{[2-(dimethylamino)ethyl]a...) Show SMILES CN(C)CCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C19H21ClN6/c1-26(2)7-6-23-17-8-14(10-21-11-17)18-12-22-13-19(25-18)24-16-5-3-4-15(20)9-16/h3-5,8-13,23H,6-7H2,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179221 (2-chloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4ccccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16ClN3O2/c1-23-15-8-10-7-12-17(11(10)9-16(15)24-2)21-22-18(12)20-14-6-4-3-5-13(14)19/h3-6,8-9H,7H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6408 ((3-Chlorophenyl)-(6-{5-[3-(4-methyl-piperazin-1-yl...) Show SMILES CN1CCN(CCCNc2cncc(c2)-c2cncc(Nc3cccc(Cl)c3)n2)CC1 Show InChI InChI=1S/C23H28ClN7/c1-30-8-10-31(11-9-30)7-3-6-27-21-12-18(14-25-15-21)22-16-26-17-23(29-22)28-20-5-2-4-19(24)13-20/h2,4-5,12-17,27H,3,6-11H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6398 (N-(3-chlorophenyl)-6-(5-{[3-(dimethylamino)propyl]...) Show SMILES CN(C)CCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C20H23ClN6/c1-27(2)8-4-7-24-18-9-15(11-22-12-18)19-13-23-14-20(26-19)25-17-6-3-5-16(21)10-17/h3,5-6,9-14,24H,4,7-8H2,1-2H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179214 (3-cyano-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]p...) Show SMILES COc1cc2Cc3c(Nc4cccc(c4)C#N)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H16N4O2/c1-24-16-8-12-7-15-18(14(12)9-17(16)25-2)22-23-19(15)21-13-5-3-4-11(6-13)10-20/h3-6,8-9H,7H2,1-2H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM6421 (N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCn3cncn3)c2)c1 Show InChI InChI=1S/C20H19ClN8/c21-16-3-1-4-17(8-16)27-20-12-23-11-19(28-20)15-7-18(10-22-9-15)25-5-2-6-29-14-24-13-26-29/h1,3-4,7-14,25H,2,5-6H2,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6388 (3-[(5-{6-[(3-fluorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(F)c2)n1 Show InChI InChI=1S/C18H18FN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6409 (N-(3-chlorophenyl)-6-(5-{[3-(morpholin-4-yl)propyl...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCN3CCOCC3)c2)c1 Show InChI InChI=1S/C22H25ClN6O/c23-18-3-1-4-19(12-18)27-22-16-25-15-21(28-22)17-11-20(14-24-13-17)26-5-2-6-29-7-9-30-10-8-29/h1,3-4,11-16,26H,2,5-10H2,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50179207 (3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against c-SRC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179217 (3-methyl-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(C)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H19N3O2/c1-11-5-4-6-13(7-11)20-19-15-8-12-9-16(23-2)17(24-3)10-14(12)18(15)21-22-19/h4-7,9-10H,8H2,1-3H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6393 ((3,4-Dichloro-phenyl)-{6-[5-(3-pyridin-4-yl-propyl...) Show SMILES Clc1ccc(Nc2cncc(n2)-c2cncc(NCCCc3ccncc3)c2)cc1Cl Show InChI InChI=1S/C23H20Cl2N6/c24-20-4-3-18(11-21(20)25)30-23-15-28-14-22(31-23)17-10-19(13-27-12-17)29-7-1-2-16-5-8-26-9-6-16/h3-6,8-15,29H,1-2,7H2,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta [7-25] (Oryctolagus cuniculus (rabbit))	BDBM6421 (N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCn3cncn3)c2)c1 Show InChI InChI=1S/C20H19ClN8/c21-16-3-1-4-17(8-16)27-20-12-23-11-19(28-20)15-7-18(10-22-9-15)25-5-2-6-29-14-24-13-26-29/h1,3-4,7-14,25H,2,5-6H2,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179215 ((6-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)ph...) Show SMILES COc1ccc-2c(Cc3c(Nc4ccccc4)[nH]nc-23)c1 Show InChI InChI=1S/C17H15N3O/c1-21-13-7-8-14-11(9-13)10-15-16(14)19-20-17(15)18-12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	217	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6407 (N-(3-Chlorophenyl)-6-[5-[[3-(1-piperazinyl)propyl]...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCN3CCNCC3)c2)c1 Show InChI InChI=1S/C22H26ClN7/c23-18-3-1-4-19(12-18)28-22-16-26-15-21(29-22)17-11-20(14-25-13-17)27-5-2-8-30-9-6-24-7-10-30/h1,3-4,11-16,24,27H,2,5-10H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6423 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-6-fl...) Show SMILES OCCCNc1cnc(F)c(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H17ClFN5O/c19-12-3-1-4-13(7-12)24-17-11-21-10-16(25-17)15-8-14(9-23-18(15)20)22-5-2-6-26/h1,3-4,7-11,22,26H,2,5-6H2,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6412 (N-(3-Chlorophenyl)-6-[5-[[4-(4-pyridinyl)butyl]ami...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCCc3ccncc3)c2)c1 Show InChI InChI=1S/C24H23ClN6/c25-20-5-3-6-21(13-20)30-24-17-28-16-23(31-24)19-12-22(15-27-14-19)29-9-2-1-4-18-7-10-26-11-8-18/h3,5-8,10-17,29H,1-2,4,9H2,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179212 (3-chloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4cccc(Cl)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16ClN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antiproliferative activity against PDGF-BB stimulated HCASMC				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6397 (2-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C17H16ClN5O/c18-13-2-1-3-14(7-13)22-17-11-20-10-16(23-17)12-6-15(9-19-8-12)21-4-5-24/h1-3,6-11,21,24H,4-5H2,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM6419 (N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3cccnc3)c2)c1 Show InChI InChI=1S/C23H21ClN6/c24-19-6-1-7-20(11-19)29-23-16-27-15-22(30-23)18-10-21(14-26-13-18)28-9-3-5-17-4-2-8-25-12-17/h1-2,4,6-8,10-16,28H,3,5,9H2,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair

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