Compile Data Set for Download or QSAR

Found 1641 hits with Last Name = 'sergienko' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50299523 (2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...) Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of TNAP using CDP-star as substrate by non-competitive Lineweaver-Burk plot				J Med Chem 52: 6919-25 (2009) Article DOI: 10.1021/jm900383s BindingDB Entry DOI: 10.7270/Q2WS8T9M
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50299523 (2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...) Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of TNAP using DEA as substrate by non-competitive Lineweaver-Burk plot				J Med Chem 52: 6919-25 (2009) Article DOI: 10.1021/jm900383s BindingDB Entry DOI: 10.7270/Q2WS8T9M
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human))	BDBM88776 (2-[4-[(Z)-[5-(4-chlorophenyl)-6-isopropoxycarbonyl...) Show SMILES CC(C)OC(=O)C1=C(C)N=c2s\c(=C/c3ccc(OCC(O)=O)cc3)c(=O)n2C1c1ccc(Cl)cc1 |c:6,t:9| Show InChI InChI=1S/C26H23ClN2O6S/c1-14(2)35-25(33)22-15(3)28-26-29(23(22)17-6-8-18(27)9-7-17)24(32)20(36-26)12-16-4-10-19(11-5-16)34-13-21(30)31/h4-12,14,23H,13H2,1-3H3,(H,30,31)/b20-12-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Competitive inhibition of recombinant HePTP expressed in Escherichia coli by Michaelis-Menten kinetic analysis				ACS Med Chem Lett 2: 113-118 (2011) Article DOI: 10.1021/ml100103p BindingDB Entry DOI: 10.7270/Q2319WWQ
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Mus musculus)	BDBM50447413 (CHEMBL3115157) Show SMILES Cc1ccc(C)c(NC(=O)CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1 Show InChI InChI=1S/C17H17N3O5S/c1-10-3-4-11(2)14(7-10)19-16(21)9-18-26(23,24)12-5-6-13-15(8-12)25-17(22)20-13/h3-8,18H,9H2,1-2H3,(H,19,21)(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Competitive inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells using p-nitrophenyl phosphate as subst...				Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50241179 ((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...) Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1 |r,c:5| Show InChI InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of TNSALP (unknown origin)				Bioorg Med Chem Lett 19: 222-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.107 BindingDB Entry DOI: 10.7270/Q2CR5T64
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM10847 (1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...) Show SMILES Cn1c2nc[nH]c2c(=O)n(C)c1=O Show InChI InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of TNSALP (unknown origin)				Bioorg Med Chem Lett 19: 222-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.107 BindingDB Entry DOI: 10.7270/Q2CR5T64
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50253982 (CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...) Show SMILES OCCNC(=O)c1cc(n[nH]1)-c1ccc(Cl)c(Cl)c1Cl Show InChI InChI=1S/C12H10Cl3N3O2/c13-7-2-1-6(10(14)11(7)15)8-5-9(18-17-8)12(20)16-3-4-19/h1-2,5,19H,3-4H2,(H,16,20)(H,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of TNSALP (unknown origin)				Bioorg Med Chem Lett 19: 222-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.107 BindingDB Entry DOI: 10.7270/Q2CR5T64
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332599 ((2E)-3-(4-bromophenyl)-1-(2-{[4-(trifluoromethyl)p...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C24H22BrF3N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)29-13-11-23(12-14-29)15-30(16-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-10H,11-16H2/b10-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332614 (3-(4-bromophenyl)-1-{2-[(4-chlorophenyl)methyl]-2,...) Show SMILES Clc1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C23H22BrClN2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-4,6-9H,11-17H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332616 (3-(4-bromophenyl)-1-(2-{[4-(trifluoromethyl)phenyl...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)C#Cc1ccc(Br)cc1 Show InChI InChI=1S/C24H20BrF3N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)29-13-11-23(12-14-29)15-30(16-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332617 (3-(4-bromophenyl)-1-{2-[(4-bromophenyl)methyl]-2,7...) Show SMILES Brc1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C23H22Br2N2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-4,6-9H,11-17H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332618 (3-(4-bromophenyl)-1-(2-{[4-(trifluoromethyl)phenyl...) Show SMILES FC(F)(F)c1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C24H22BrF3N2O/c25-21-8-3-18(4-9-21)5-10-22(31)30-13-11-23(12-14-30)16-29(17-23)15-19-1-6-20(7-2-19)24(26,27)28/h1-4,6-9H,11-17H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332619 (3-(4-bromophenyl)-1-{2-[(4-methoxyphenyl)carbonyl]...) Show SMILES COc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)C#Cc1ccc(Br)cc1 Show InChI InChI=1S/C24H23BrN2O3/c1-30-21-9-5-19(6-10-21)23(29)27-16-24(17-27)12-14-26(15-13-24)22(28)11-4-18-2-7-20(25)8-3-18/h2-3,5-10H,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332621 (3-(4-chlorophenyl)-1-{2-[(4-chlorophenyl)carbonyl]...) Show SMILES Clc1ccc(cc1)C#CC(=O)N1CCC2(CN(C2)C(=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C23H20Cl2N2O2/c24-19-6-1-17(2-7-19)3-10-21(28)26-13-11-23(12-14-26)15-27(16-23)22(29)18-4-8-20(25)9-5-18/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332622 (3-(4-chlorophenyl)-1-{2-[(4-fluorophenyl)carbonyl]...) Show SMILES Fc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)C#Cc1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClFN2O2/c24-19-6-1-17(2-7-19)3-10-21(28)26-13-11-23(12-14-26)15-27(16-23)22(29)18-4-8-20(25)9-5-18/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332623 (3-(4-chlorophenyl)-1-(2-{[4-(trifluoromethyl)pheny...) Show SMILES FC(F)(F)c1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C24H22ClF3N2O/c25-21-8-3-18(4-9-21)5-10-22(31)30-13-11-23(12-14-30)16-29(17-23)15-19-1-6-20(7-2-19)24(26,27)28/h1-4,6-9H,11-17H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332624 (3-(4-chlorophenyl)-1-(2-{[4-(trifluoromethyl)pheny...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)C#Cc1ccc(Cl)cc1 Show InChI InChI=1S/C24H20ClF3N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)29-13-11-23(12-14-29)15-30(16-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332625 (3-(4-chlorophenyl)-1-(7-{[4-(trifluoromethyl)pheny...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)C#Cc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C24H20ClF3N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)30-15-23(16-30)11-13-29(14-12-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332627 (3-(4-chlorophenyl)-1-{2-[(4-chlorophenyl)methyl]-2...) Show SMILES Clc1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C23H22Cl2N2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-4,6-9H,11-17H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332629 (3-(4-chlorophenyl)-1-{7-[(4-chlorophenyl)carbonyl]...) Show SMILES Clc1ccc(cc1)C#CC(=O)N1CC2(C1)CCN(CC2)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20Cl2N2O2/c24-19-6-1-17(2-7-19)3-10-21(28)27-15-23(16-27)11-13-26(14-12-23)22(29)18-4-8-20(25)9-5-18/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332632 (1-{2-[(4-chlorophenyl)carbonyl]-2,7-diazaspiro[3.5...) Show SMILES Fc1ccc(cc1)C#CC(=O)N1CCC2(CN(C2)C(=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C23H20ClFN2O2/c24-19-6-4-18(5-7-19)22(29)27-15-23(16-27)11-13-26(14-12-23)21(28)10-3-17-1-8-20(25)9-2-17/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332633 (3-(4-fluorophenyl)-1-(2-{[4-(trifluoromethyl)pheny...) Show SMILES Fc1ccc(cc1)C#CC(=O)N1CCC2(CN(C2)C(=O)c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C24H20F4N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)29-13-11-23(12-14-29)15-30(16-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332636 (3-(4-chlorophenyl)-1-{7-[(4-methoxyphenyl)carbonyl...) Show SMILES COc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)C#Cc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C24H23ClN2O3/c1-30-21-9-5-19(6-10-21)23(29)26-14-12-24(13-15-26)16-27(17-24)22(28)11-4-18-2-7-20(25)8-3-18/h2-3,5-10H,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332640 (1-{7-[(4-bromophenyl)carbonyl]-2,7-diazaspiro[3.5]...) Show SMILES Fc1ccc(cc1)C#CC(=O)N1CC2(C1)CCN(CC2)C(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C23H20BrFN2O2/c24-19-6-4-18(5-7-19)22(29)26-13-11-23(12-14-26)15-27(16-23)21(28)10-3-17-1-8-20(25)9-2-17/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332641 (3-(4-fluorophenyl)-1-(7-{[4-(trifluoromethyl)pheny...) Show SMILES Fc1ccc(cc1)C#CC(=O)N1CC2(C1)CCN(CC2)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H20F4N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)30-15-23(16-30)11-13-29(14-12-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-2,4-9H,11-16H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332546 ((2E)-1-{7-[(2E)-3-(4-bromophenyl)prop-2-enoyl]-2,7...) Show SMILES Brc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C25H24Br2N2O2/c26-21-7-1-19(2-8-21)5-11-23(30)28-15-13-25(14-16-28)17-29(18-25)24(31)12-6-20-3-9-22(27)10-4-20/h1-12H,13-18H2/b11-5+,12-6+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332547 ((2E)-3-(4-bromophenyl)-1-{7-[(3-bromophenyl)carbon...) Show SMILES Brc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C23H22Br2N2O2/c24-19-7-4-17(5-8-19)6-9-21(28)27-15-23(16-27)10-12-26(13-11-23)22(29)18-2-1-3-20(25)14-18/h1-9,14H,10-13,15-16H2/b9-6+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332549 (5-chloroindol-2-yl 2-[(3-fluorophenyl)methyl]-2,7-...) Show SMILES Fc1cccc(CN2CC3(C2)CCN(CC3)C(=O)c2cc3cc(Cl)ccc3[nH]2)c1 Show InChI InChI=1S/C23H23ClFN3O/c24-18-4-5-20-17(11-18)12-21(26-20)22(29)28-8-6-23(7-9-28)14-27(15-23)13-16-2-1-3-19(25)10-16/h1-5,10-12,26H,6-9,13-15H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332551 ((2E)-3-(4-bromophenyl)-1-{2-[(4-chlorophenyl)methy...) Show SMILES Clc1ccc(CN2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C23H24BrClN2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-10H,11-17H2/b10-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332552 ((2E)-3-(4-bromophenyl)-1-[2-(phenylcarbonyl)-2,7-d...) Show SMILES Brc1ccc(\C=C\C(=O)N2CCC3(CN(C3)C(=O)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C23H23BrN2O2/c24-20-9-6-18(7-10-20)8-11-21(27)25-14-12-23(13-15-25)16-26(17-23)22(28)19-4-2-1-3-5-19/h1-11H,12-17H2/b11-8+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332553 ((2E)-3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)methy...) Show SMILES Fc1ccc(CN2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C23H24BrFN2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-10H,11-17H2/b10-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332554 ((2E)-1-{2-[(3,4-dimethoxyphenyl)carbonyl]-2,7-diaz...) Show SMILES COc1ccc(cc1OC)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C25H27BrN2O4/c1-31-21-9-6-19(15-22(21)32-2)24(30)28-16-25(17-28)11-13-27(14-12-25)23(29)10-5-18-3-7-20(26)8-4-18/h3-10,15H,11-14,16-17H2,1-2H3/b10-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332555 ((2E)-1-{2-[(3,5-dichlorophenyl)carbonyl]-2,7-diaza...) Show SMILES Clc1cc(Cl)cc(c1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C23H21BrCl2N2O2/c24-18-4-1-16(2-5-18)3-6-21(29)27-9-7-23(8-10-27)14-28(15-23)22(30)17-11-19(25)13-20(26)12-17/h1-6,11-13H,7-10,14-15H2/b6-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332556 ((2E)-1-{2-[(2,6-dichlorophenyl)methyl]-2,7-diazasp...) Show SMILES Clc1cccc(Cl)c1CN1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C23H23BrCl2N2O/c24-18-7-4-17(5-8-18)6-9-22(29)28-12-10-23(11-13-28)15-27(16-23)14-19-20(25)2-1-3-21(19)26/h1-9H,10-16H2/b9-6+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332557 ((2E)-3-(4-bromophenyl)-1-{2-[(3-methylphenyl)carbo...) Show SMILES Cc1cccc(c1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C24H25BrN2O2/c1-18-3-2-4-20(15-18)23(29)27-16-24(17-27)11-13-26(14-12-24)22(28)10-7-19-5-8-21(25)9-6-19/h2-10,15H,11-14,16-17H2,1H3/b10-7+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332562 (5-chloroindol-2-yl 2-[(4-fluorophenyl)methyl]-2,7-...) Show SMILES Fc1ccc(CN2CC3(C2)CCN(CC3)C(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C23H23ClFN3O/c24-18-3-6-20-17(11-18)12-21(26-20)22(29)28-9-7-23(8-10-28)14-27(15-23)13-16-1-4-19(25)5-2-16/h1-6,11-12,26H,7-10,13-15H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332563 (5-chloroindol-2-yl 7-{[3-fluoro-4-(trifluoromethyl...) Show SMILES Fc1cc(ccc1C(F)(F)F)C(=O)N1CCC2(CN(C2)C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1 Show InChI InChI=1S/C24H20ClF4N3O2/c25-16-2-4-19-15(9-16)11-20(30-19)22(34)32-12-23(13-32)5-7-31(8-6-23)21(33)14-1-3-17(18(26)10-14)24(27,28)29/h1-4,9-11,30H,5-8,12-13H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332564 ((2E)-3-(4-bromophenyl)-1-{7-[(4-chlorophenyl)carbo...) Show SMILES Clc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C23H22BrClN2O2/c24-19-6-1-17(2-7-19)3-10-21(28)27-15-23(16-27)11-13-26(14-12-23)22(29)18-4-8-20(25)9-5-18/h1-10H,11-16H2/b10-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332565 ((2E)-3-(4-bromophenyl)-1-{7-[(4-fluorophenyl)carbo...) Show SMILES Fc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C23H22BrFN2O2/c24-19-6-1-17(2-7-19)3-10-21(28)27-15-23(16-27)11-13-26(14-12-23)22(29)18-4-8-20(25)9-5-18/h1-10H,11-16H2/b10-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332566 ((2E)-3-(4-bromophenyl)-1-(7-{[4-(trifluoromethyl)p...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C24H22BrF3N2O2/c25-20-8-1-17(2-9-20)3-10-21(31)30-15-23(16-30)11-13-29(14-12-23)22(32)18-4-6-19(7-5-18)24(26,27)28/h1-10H,11-16H2/b10-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332567 ((2E)-3-(4-bromophenyl)-1-(7-{[4-fluoro-3-(trifluor...) Show SMILES Fc1ccc(cc1C(F)(F)F)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C24H21BrF4N2O2/c25-18-5-1-16(2-6-18)3-8-21(32)31-14-23(15-31)9-11-30(12-10-23)22(33)17-4-7-20(26)19(13-17)24(27,28)29/h1-8,13H,9-12,14-15H2/b8-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332573 ((2E)-3-(3,4-dichlorophenyl)-1-{7-[(4-fluorophenyl)...) Show SMILES Fc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C23H21Cl2FN2O2/c24-19-7-1-16(13-20(19)25)2-8-21(29)28-14-23(15-28)9-11-27(12-10-23)22(30)17-3-5-18(26)6-4-17/h1-8,13H,9-12,14-15H2/b8-2+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332574 ((2E)-3-(3,4-dichlorophenyl)-1-{7-[(4-chlorophenyl)...) Show SMILES Clc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C23H21Cl3N2O2/c24-18-5-3-17(4-6-18)22(30)27-11-9-23(10-12-27)14-28(15-23)21(29)8-2-16-1-7-19(25)20(26)13-16/h1-8,13H,9-12,14-15H2/b8-2+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332550 (5-chloroindol-2-yl 2-[(4-fluorophenyl)carbonyl]-2,...) Show SMILES Fc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C23H21ClFN3O2/c24-17-3-6-19-16(11-17)12-20(26-19)22(30)27-9-7-23(8-10-27)13-28(14-23)21(29)15-1-4-18(25)5-2-15/h1-6,11-12,26H,7-10,13-14H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332645 (5-chloroindol-2-yl 9-{[3-fluoro-4-(trifluoromethyl...) Show SMILES Fc1cc(ccc1C(F)(F)F)C(=O)N1CCC2(CCN(CC2)C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1 Show InChI InChI=1S/C26H24ClF4N3O2/c27-18-2-4-21-17(13-18)15-22(32-21)24(36)34-11-7-25(8-12-34)5-9-33(10-6-25)23(35)16-1-3-19(20(28)14-16)26(29,30)31/h1-4,13-15,32H,5-12H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332646 (5-bromoindol-2-yl 7-{[4-(trifluoromethyl)phenyl]ca...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)c2cc3cc(Br)ccc3[nH]2)CC1 Show InChI InChI=1S/C24H21BrF3N3O2/c25-18-5-6-19-16(11-18)12-20(29-19)22(33)31-13-23(14-31)7-9-30(10-8-23)21(32)15-1-3-17(4-2-15)24(26,27)28/h1-6,11-12,29H,7-10,13-14H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332648 ((2E)-3-(4-bromophenyl)-1-{2-[(4-chlorophenyl)carbo...) Show SMILES Clc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C23H22BrClN2O2/c24-19-6-1-17(2-7-19)3-10-21(28)26-13-11-23(12-14-26)15-27(16-23)22(29)18-4-8-20(25)9-5-18/h1-10H,11-16H2/b10-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332613 (3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)methyl]-2,...) Show SMILES Fc1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C23H22BrFN2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-4,6-9H,11-17H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332598 ((2E)-3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)carbo...) Show SMILES Fc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C23H22BrFN2O2/c24-19-6-1-17(2-7-19)3-10-21(28)26-13-11-23(12-14-26)15-27(16-23)22(29)18-4-8-20(25)9-5-18/h1-10H,11-16H2/b10-3+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332575 ((2E)-3-(3,4-dichlorophenyl)-1-(7-{[4-(trifluoromet...) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C24H21Cl2F3N2O2/c25-19-7-1-16(13-20(19)26)2-8-21(32)31-14-23(15-31)9-11-30(12-10-23)22(33)17-3-5-18(6-4-17)24(27,28)29/h1-8,13H,9-12,14-15H2/b8-2+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair

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