Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Homo sapiens (Human)) | BDBM10597 ((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.0260 | -60.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50262988 (CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 0.120 | -56.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50277608 (CHEMBL4173067) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50089616 (4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.70 | -50.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50330030 (CHEMBL1269632 | [(3-Bromophenyl)-(3-hydroxyphenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Baylor University Curated by ChEMBL | Assay Description Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured... | Bioorg Med Chem Lett 27: 1304-1310 (2017) Article DOI: 10.1016/j.bmcl.2016.12.039 BindingDB Entry DOI: 10.7270/Q23B62C1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5-HT2A receptor in human frontal cortex after 30 mins by scintillation counting | Bioorg Med Chem Lett 23: 1953-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.045 BindingDB Entry DOI: 10.7270/Q2S183VK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM10441 ((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 4.60 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50232473 (CHEMBL4087627) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Baylor University Curated by ChEMBL | Assay Description Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured... | Bioorg Med Chem Lett 27: 1304-1310 (2017) Article DOI: 10.1016/j.bmcl.2016.12.039 BindingDB Entry DOI: 10.7270/Q23B62C1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in human frontal cortex after 30 mins by scintillation counting | Bioorg Med Chem Lett 23: 1953-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.045 BindingDB Entry DOI: 10.7270/Q2S183VK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]raclopride from D2 receptor in human corpus striatum after 30 mins by scintillation counting | Bioorg Med Chem Lett 23: 1953-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.045 BindingDB Entry DOI: 10.7270/Q2S183VK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Mus musculus (mouse)) | BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 18 | -44.2 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402859 (CHEMBL2205591) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 81.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209260 ((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50241461 (3,7-bis(dimethylamino)phenothiazin-5-ium chloride ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 110 | -39.7 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM50277608 (CHEMBL4173067) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209260 ((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of mouse MDC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402858 (CHEMBL2205592) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209278 ((S)-N-(1-(2-carbamoylphenethyl)piperidin-4-yl)-1-(...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402864 (CHEMBL2205615) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 241 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Mus musculus (mouse)) | BDBM120262 (EDROPHONIUM BROMIDE | EDROPHONIUM CHLORIDE | Edrop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 250 | -37.7 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209261 ((S)-N-(1-(2-fluorophenethyl)piperidin-4-yl)-1-(5-c...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209251 ((S)-N-(1-(2-aminophenethyl)piperidin-4-yl)-1-(5-ch...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Mus musculus (mouse)) | BDBM120263 (N-methylacridinium) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 310 | -37.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402863 (CHEMBL2205616) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 347 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209257 ((S)-N-(1-(3-chlorophenethyl)piperidin-4-yl)-1-(5-c...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209279 ((S)-N-(1-(2-(trifluoromethyl)phenethyl)piperidin-4...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50523582 (CHEMBL4447657) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 426 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 29: 1380-1385 (2019) Article DOI: 10.1016/j.bmcl.2019.03.039 BindingDB Entry DOI: 10.7270/Q2348PSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402857 (CHEMBL2205593) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 444 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209262 ((S)-N-(1-(2-chlorophenethyl)piperidin-4-yl)-1-(5-c...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Mus musculus (mouse)) | BDBM50060582 (1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 460 | -36.2 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209265 ((S)-N-(1-(3-methoxyphenethyl)piperidin-4-yl)-1-(5-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209260 ((S)-1-(5-chloronaphthalen-2-ylsulfonyl)-N-methyl-N...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209253 ((S)-2-(2-(4-(1-(5-chloronaphthalen-2-ylsulfonyl)-N...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209268 ((S)-N-methyl-1-(naphthalen-2-ylsulfonyl)-N-(1-phen...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Rattus norvegicus (Rat)) | BDBM50402859 (CHEMBL2205591) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 594 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50523610 (CHEMBL4472207) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 616 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 29: 1380-1385 (2019) Article DOI: 10.1016/j.bmcl.2019.03.039 BindingDB Entry DOI: 10.7270/Q2348PSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209255 ((S)-N-methyl-1-(naphthalen-2-ylsulfonyl)-N-(1-(3-p...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Rattus norvegicus (Rat)) | BDBM50402857 (CHEMBL2205593) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM31904 (CHEMBL345124 | Propidium | Propidium Iodide, 2 | p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 660 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50423877 (DIHYDROTANSHINONE | Dihydrotanshinone I | acs.jmed...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 750 | -35.0 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209258 ((S)-N-(1-(4-chlorophenethyl)piperidin-4-yl)-1-(5-c...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50523611 (CHEMBL4453601) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 29: 1380-1385 (2019) Article DOI: 10.1016/j.bmcl.2019.03.039 BindingDB Entry DOI: 10.7270/Q2348PSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209269 ((S)-1-(5-fluoronaphthalen-2-ylsulfonyl)-N-methyl-N...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402860 (CHEMBL2205588) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 899 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402861 (CHEMBL2205584) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 904 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50402862 (CHEMBL2205620) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 999 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis | Bioorg Med Chem Lett 22: 7314-21 (2012) Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50100134 (2-(4-Dimethylamino-phenyl)-3,6-dimethyl-benzothiaz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.00E+3 | -34.2 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Mayo Clinic College of Medicine | Assay Description Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we... | Biochemistry 52: 7486-99 (2013) Article DOI: 10.1021/bi401043w BindingDB Entry DOI: 10.7270/Q24X56GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50209263 ((S)-N-(1-benzylpiperidin-4-yl)-N-methyl-1-(naphtha...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of human TARC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | Bioorg Med Chem Lett 17: 3141-5 (2007) Article DOI: 10.1016/j.bmcl.2007.03.030 BindingDB Entry DOI: 10.7270/Q2TD9X2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50523601 (CHEMBL4467163) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 29: 1380-1385 (2019) Article DOI: 10.1016/j.bmcl.2019.03.039 BindingDB Entry DOI: 10.7270/Q2348PSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50523622 (CHEMBL4525823) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 29: 1380-1385 (2019) Article DOI: 10.1016/j.bmcl.2019.03.039 BindingDB Entry DOI: 10.7270/Q2348PSJ | |||||||||||
More data for this Ligand-Target Pair |
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