Compile Data Set for Download or QSAR

Found 331 hits with Last Name = 'shieh' and Initial = 'cc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86244 (A-312110) Show SMILES Fc1ccc(cc1I)[C@@H]1C2C(=O)COCC2=NC2=C1S(=O)(=O)CC2 |r,c:17,19| Show InChI InChI=1S/C16H13FINO4S/c17-9-2-1-8(5-10(9)18)14-15-12(6-23-7-13(15)20)19-11-3-4-24(21,22)16(11)14/h1-2,5,14-15H,3-4,6-7H2/t14-,15?/m1/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86250 (CAS_60559-98-0 | NSC_43345 | P1075) Show SMILES CCC(C)(C)N=C(NC#N)Nc1cccnc1 |w:5.4| Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86250 (CAS_60559-98-0 | NSC_43345 | P1075) Show SMILES CCC(C)(C)N=C(NC#N)Nc1cccnc1 |w:5.4| Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Br J Pharmacol 143: 81-90 (2004) Article DOI: 10.1038/sj.bjp.0705908 BindingDB Entry DOI: 10.7270/Q2QR4VQ0
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86247 (BAY X 9228 | CAS_3038059 | NSC_3038059) Show SMILES CCOc1ccccc1N=C(C[N+]([O-])=O)NC(C)C(C)(C)C |w:9.9| Show InChI InChI=1S/C16H25N3O3/c1-6-22-14-10-8-7-9-13(14)18-15(11-19(20)21)17-12(2)16(3,4)5/h7-10,12H,6,11H2,1-5H3,(H,17,18)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86250 (CAS_60559-98-0 | NSC_43345 | P1075) Show SMILES CCC(C)(C)N=C(NC#N)Nc1cccnc1 |w:5.4| Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	20.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86247 (BAY X 9228 | CAS_3038059 | NSC_3038059) Show SMILES CCOc1ccccc1N=C(C[N+]([O-])=O)NC(C)C(C)(C)C |w:9.9| Show InChI InChI=1S/C16H25N3O3/c1-6-22-14-10-8-7-9-13(14)18-15(11-19(20)21)17-12(2)16(3,4)5/h7-10,12H,6,11H2,1-5H3,(H,17,18)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86245 (CAS_85371-64-8 | NSC_4826 | PINACIDIL) Show SMILES CC(N=C(NC#N)Nc1ccncc1)C(C)(C)C |w:2.1| Show InChI InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86251 (CAS_94535-50-9 | CROMAKALIM (-) | NSC_93504) Show SMILES CC1(C)Oc2ccc(cc2C(C1O)N1CCCC1=O)C#N Show InChI InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86245 (CAS_85371-64-8 | NSC_4826 | PINACIDIL) Show SMILES CC(N=C(NC#N)Nc1ccncc1)C(C)(C)C |w:2.1| Show InChI InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86249 (ZD 6169 | ZD-6169) Show SMILES C[C@](O)(C(=O)Nc1ccc(cc1)C(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H14F3NO3/c1-16(24,17(18,19)20)15(23)21-13-9-7-12(8-10-13)14(22)11-5-3-2-4-6-11/h2-10,24H,1H3,(H,21,23)/t16-/m0/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	451	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86251 (CAS_94535-50-9 | CROMAKALIM (-) | NSC_93504) Show SMILES CC1(C)Oc2ccc(cc2C(C1O)N1CCCC1=O)C#N Show InChI InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	542	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86249 (ZD 6169 | ZD-6169) Show SMILES C[C@](O)(C(=O)Nc1ccc(cc1)C(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H14F3NO3/c1-16(24,17(18,19)20)15(23)21-13-9-7-12(8-10-13)14(22)11-5-3-2-4-6-11/h2-10,24H,1H3,(H,21,23)/t16-/m0/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86246 (zm244085) Show SMILES O=C1CCCC2=NC3=C(C(C12)c1cccc(c1)C#N)C(=O)CCC3 |c:7,t:5| Show InChI InChI=1S/C20H18N2O2/c21-11-12-4-1-5-13(10-12)18-19-14(6-2-8-16(19)23)22-15-7-3-9-17(24)20(15)18/h1,4-5,10,18-19H,2-3,6-9H2	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	671	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86246 (zm244085) Show SMILES O=C1CCCC2=NC3=C(C(C12)c1cccc(c1)C#N)C(=O)CCC3 |c:7,t:5| Show InChI InChI=1S/C20H18N2O2/c21-11-12-4-1-5-13(10-12)18-19-14(6-2-8-16(19)23)22-15-7-3-9-17(24)20(15)18/h1,4-5,10,18-19H,2-3,6-9H2	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	2.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1| Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta (GUINEA PIG)	BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1| Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Mol Pharmacol 64: 143-53 (2003) Article DOI: 10.1124/mol.64.1.143 BindingDB Entry DOI: 10.7270/Q22B8WMJ
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330935 (CHEMBL1277958 | N-(m-Tolyl)-6-(4-ethoxyphenyl)-pyr...) Show SMILES CCOc1ccc(cc1)-c1cncc(n1)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C20H19N3O2/c1-3-25-17-9-7-15(8-10-17)18-12-21-13-19(23-18)20(24)22-16-6-4-5-14(2)11-16/h4-13H,3H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330949 (CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...) Show SMILES CCOc1ccc(cc1)-c1cncc(n1)C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C21H21N3O2/c1-4-26-18-7-5-16(6-8-18)19-12-22-13-20(24-19)21(25)23-17-10-14(2)9-15(3)11-17/h5-13H,4H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329223 (CHEMBL1270797 | N-(3,5-dimethylphenyl)-5-(4-(trifl...) Show SMILES Cc1cc(C)cc(NC(=O)c2ccc(o2)-c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C20H16F3NO3/c1-12-9-13(2)11-15(10-12)24-19(25)18-8-7-17(26-18)14-3-5-16(6-4-14)27-20(21,22)23/h3-11H,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330948 (CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...) Show SMILES CCOc1ccc(cc1)-c1cncc(n1)C(=O)NCc1ccccc1C Show InChI InChI=1S/C21H21N3O2/c1-3-26-18-10-8-16(9-11-18)19-13-22-14-20(24-19)21(25)23-12-17-7-5-4-6-15(17)2/h4-11,13-14H,3,12H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329211 (5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...) Show SMILES Cc1ccccc1CNC(=O)c1cncc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN2O/c1-14-4-2-3-5-16(14)13-23-20(24)18-10-17(11-22-12-18)15-6-8-19(21)9-7-15/h2-12H,13H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329203 (5-(4-chlorophenyl)-N-((2-(2,2,2-trifluoroethoxy)py...) Show SMILES FC(F)(F)COc1ncccc1CNC(=O)c1cncc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClF3N3O2/c21-17-5-3-13(4-6-17)15-8-16(10-25-9-15)18(28)27-11-14-2-1-7-26-19(14)29-12-20(22,23)24/h1-10H,11-12H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330933 (CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(n2)-c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H16ClN3O/c1-12-7-13(2)9-16(8-12)22-19(24)18-11-21-10-17(23-18)14-3-5-15(20)6-4-14/h3-11H,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329210 (CHEMBL1269883 | N-(2-chlorobenzyl)-5-(4-chlorophen...) Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1ccccc1Cl Show InChI InChI=1S/C19H14Cl2N2O/c20-17-7-5-13(6-8-17)15-9-16(11-22-10-15)19(24)23-12-14-3-1-2-4-18(14)21/h1-11H,12H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330945 (CHEMBL1278223 | N-(m-Tolyl)-6-(4-trifluoromethoxyp...) Show SMILES Cc1cccc(NC(=O)c2cncc(n2)-c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C19H14F3N3O2/c1-12-3-2-4-14(9-12)24-18(26)17-11-23-10-16(25-17)13-5-7-15(8-6-13)27-19(20,21)22/h2-11H,1H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330937 (CHEMBL1277513 | N-(m-Tolyl)-6-(4-chlorophenyl)-pyr...) Show SMILES Cc1cccc(NC(=O)c2cncc(n2)-c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C18H14ClN3O/c1-12-3-2-4-15(9-12)21-18(23)17-11-20-10-16(22-17)13-5-7-14(19)8-6-13/h2-11H,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330941 (CHEMBL1277512 | N-(3,5-Dimethoxyphenyl)-6-(4-chlor...) Show SMILES COc1cc(NC(=O)c2cncc(n2)-c2ccc(Cl)cc2)cc(OC)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-15-7-14(8-16(9-15)26-2)22-19(24)18-11-21-10-17(23-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329206 (5-(4-chlorophenyl)-N-((2-ethoxypyridin-3-yl)methyl...) Show SMILES CCOc1ncccc1CNC(=O)c1cncc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18ClN3O2/c1-2-26-20-15(4-3-9-23-20)13-24-19(25)17-10-16(11-22-12-17)14-5-7-18(21)8-6-14/h3-12H,2,13H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329218 (CHEMBL1271105 | N-(3,5-dimethylphenyl)-5-(4-(trifl...) Show SMILES Cc1cc(C)cc(NC(=O)c2nsc(n2)-c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C18H14F3N3O2S/c1-10-7-11(2)9-13(8-10)22-16(25)15-23-17(27-24-15)12-3-5-14(6-4-12)26-18(19,20)21/h3-9H,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329209 (5-(4-chlorophenyl)-N-(2-(piperidin-1-yl)benzyl)nic...) Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1ccccc1N1CCCCC1 Show InChI InChI=1S/C24H24ClN3O/c25-22-10-8-18(9-11-22)20-14-21(16-26-15-20)24(29)27-17-19-6-2-3-7-23(19)28-12-4-1-5-13-28/h2-3,6-11,14-16H,1,4-5,12-13,17H2,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM50329205 (5-(4-chlorophenyl)-N-((2-(piperidin-1-yl)pyridin-3...) Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1cccnc1N1CCCCC1 Show InChI InChI=1S/C23H23ClN4O/c24-21-8-6-17(7-9-21)19-13-20(15-25-14-19)23(29)27-16-18-5-4-10-26-22(18)28-11-2-1-3-12-28/h4-10,13-15H,1-3,11-12,16H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50212239 (5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...) Show SMILES COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1 Show InChI InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 channel expressed in HEK293 cells at -40 mV by patch clamp method				Proc Natl Acad Sci USA 104: 8520-5 (2007) Article DOI: 10.1073/pnas.0611364104 BindingDB Entry DOI: 10.7270/Q2J10411
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50212239 (5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...) Show SMILES COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1 Show InChI InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant Nav 1.8 channel expressed in HEK293 cells				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50212239 (5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...) Show SMILES COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1 Show InChI InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 channel expressed in human HEK293 cells by patch clamp method				Proc Natl Acad Sci USA 104: 8520-5 (2007) Article DOI: 10.1073/pnas.0611364104 BindingDB Entry DOI: 10.7270/Q2J10411
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50212239 (5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...) Show SMILES COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1 Show InChI InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330944 (CHEMBL1278044 | N-(3,5-Dimethylphenyl)-6-(4-cyanop...) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(n2)-c2ccc(cc2)C#N)c1 Show InChI InChI=1S/C20H16N4O/c1-13-7-14(2)9-17(8-13)23-20(25)19-12-22-11-18(24-19)16-5-3-15(10-21)4-6-16/h3-9,11-12H,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM50329211 (5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...) Show SMILES Cc1ccccc1CNC(=O)c1cncc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN2O/c1-14-4-2-3-5-16(14)13-23-20(24)18-10-17(11-22-12-18)15-6-8-19(21)9-7-15/h2-12H,13H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329213 (5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinam...) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(c2)-c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C20H17ClN2O/c1-13-7-14(2)9-19(8-13)23-20(24)17-10-16(11-22-12-17)15-3-5-18(21)6-4-15/h3-12H,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329208 (5-(4-chlorophenyl)-N-(2-morpholinobenzyl)nicotinam...) Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1ccccc1N1CCOCC1 Show InChI InChI=1S/C23H22ClN3O2/c24-21-7-5-17(6-8-21)19-13-20(15-25-14-19)23(28)26-16-18-3-1-2-4-22(18)27-9-11-29-12-10-27/h1-8,13-15H,9-12,16H2,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM50330949 (CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...) Show SMILES CCOc1ccc(cc1)-c1cncc(n1)C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C21H21N3O2/c1-4-26-18-7-5-16(6-8-18)19-12-22-13-20(24-19)21(25)23-17-10-14(2)9-15(3)11-17/h5-13H,4H2,1-3H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329205 (5-(4-chlorophenyl)-N-((2-(piperidin-1-yl)pyridin-3...) Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1cccnc1N1CCCCC1 Show InChI InChI=1S/C23H23ClN4O/c24-21-8-6-17(7-9-21)19-13-20(15-25-14-19)23(29)27-16-18-5-4-10-26-22(18)28-11-2-1-3-12-28/h4-10,13-15H,1-3,11-12,16H2,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM50330945 (CHEMBL1278223 | N-(m-Tolyl)-6-(4-trifluoromethoxyp...) Show SMILES Cc1cccc(NC(=O)c2cncc(n2)-c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C19H14F3N3O2/c1-12-3-2-4-14(9-12)24-18(26)17-11-23-10-16(25-17)13-5-7-15(8-6-13)27-19(20,21)22/h2-11H,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330942 (CHEMBL1278224 | N-(2-methylbenzyl)-6-(4-(trifluoro...) Show SMILES Cc1ccccc1CNC(=O)c1cncc(n1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C20H16F3N3O2/c1-13-4-2-3-5-15(13)10-25-19(27)18-12-24-11-17(26-18)14-6-8-16(9-7-14)28-20(21,22)23/h2-9,11-12H,10H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM50330948 (CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...) Show SMILES CCOc1ccc(cc1)-c1cncc(n1)C(=O)NCc1ccccc1C Show InChI InChI=1S/C21H21N3O2/c1-3-26-18-10-8-16(9-11-18)19-13-22-14-20(24-19)21(25)23-12-17-7-5-4-6-15(17)2/h4-11,13-14H,3,12H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330938 (CHEMBL1277607 | N-(4-Chlorophenethyl)-6-(4-chlorop...) Show SMILES Clc1ccc(CCNC(=O)c2cncc(n2)-c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C19H15Cl2N3O/c20-15-5-1-13(2-6-15)9-10-23-19(25)18-12-22-11-17(24-18)14-3-7-16(21)8-4-14/h1-8,11-12H,9-10H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330932 (CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1N1CCOCC1 Show InChI InChI=1S/C22H20F3N5O3/c23-22(24,25)33-17-5-3-15(4-6-17)18-13-26-14-19(29-18)21(31)28-12-16-2-1-7-27-20(16)30-8-10-32-11-9-30/h1-7,13-14H,8-12H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329217 (CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(n2)-c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C20H16F3N3O2/c1-12-7-13(2)9-15(8-12)25-19(27)18-11-24-10-17(26-18)14-3-5-16(6-4-14)28-20(21,22)23/h3-11H,1-2H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329217 (CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(n2)-c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C20H16F3N3O2/c1-12-7-13(2)9-15(8-12)25-19(27)18-11-24-10-17(26-18)14-3-5-16(6-4-14)28-20(21,22)23/h3-11H,1-2H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329212 (CHEMBL1271417 | N-benzyl-5-(4-chlorophenyl)nicotin...) Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C19H15ClN2O/c20-18-8-6-15(7-9-18)16-10-17(13-21-12-16)19(23)22-11-14-4-2-1-3-5-14/h1-10,12-13H,11H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50329202 (5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...) Show SMILES Cc1cc(C)cc(NC(=O)c2cncc(c2)-c2ccc(cc2)C#N)c1 Show InChI InChI=1S/C21H17N3O/c1-14-7-15(2)9-20(8-14)24-21(25)19-10-18(12-23-13-19)17-5-3-16(11-22)4-6-17/h3-10,12-13H,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.8 by electrophysiology				Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6
					More data for this Ligand-Target Pair

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