Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Homo sapiens (Human)) | BDBM50336997 (2-chloro-4-((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assay | ACS Med Chem Lett 2: 124-129 (2011) Article DOI: 10.1021/ml1002508 BindingDB Entry DOI: 10.7270/Q2JQ119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assay | ACS Med Chem Lett 2: 124-129 (2011) Article DOI: 10.1021/ml1002508 BindingDB Entry DOI: 10.7270/Q2JQ119N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM8885 ((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank PDB Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assay | ACS Med Chem Lett 2: 124-129 (2011) Article DOI: 10.1021/ml1002508 BindingDB Entry DOI: 10.7270/Q2JQ119N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM8903 ((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to progesterone receptor | ACS Med Chem Lett 2: 124-129 (2011) Article DOI: 10.1021/ml1002508 BindingDB Entry DOI: 10.7270/Q2JQ119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50367916 (METHYLTRIENOLONE | Metribolone | R-1881) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331713 (5,7-dichloro-3-(trifluoromethyl)-1,2,3,4-tetrahydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331698 (5,6-dichloro-9H-carbazol-1-ol | CHEMBL1288959) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331708 (6,7-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM8885 ((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank PDB Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331697 (2-bromo-6,7-dichloro-9H-carbazol-1-ol | CHEMBL1288...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331710 (6,7-dichloro-1-(perfluoroethyl)-2,3,4,9-tetrahydro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331701 (6,8-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331702 (5,8-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331704 (8-chloro-6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331709 (5,6-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331712 (6,8-dichloro-2,2-difluoro-1-(trifluoromethyl)-2,3,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331707 (1-hydroxy-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331703 (2,4-dichloro-6-(trifluoromethyl)-5,6,7,8,9,10-hexa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50336997 (2-chloro-4-((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxa...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to progesterone receptor | ACS Med Chem Lett 2: 124-129 (2011) Article DOI: 10.1021/ml1002508 BindingDB Entry DOI: 10.7270/Q2JQ119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331699 (2-benzyl-6,7-dichloro-9H-carbazol-1-ol | CHEMBL129...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331700 (2-benzyl-5,6-dichloro-9H-carbazol-1-ol | CHEMBL129...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331695 (6-bromo-9H-carbazol-1-ol | CHEMBL1288956) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331696 (8-hydroxy-9H-carbazole-3-carbonitrile | CHEMBL1288...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331706 (1-hydroxy-1-methyl-2,3,4,9-tetrahydro-1H-carbazole...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331711 (1-hydroxy-1-(perfluoroethyl)-2,3,4,9-tetrahydro-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50331705 (6,7-dichloro-1-methyl-2,3,4,9-tetrahydro-1H-carbaz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Radius Health, Inc. Curated by ChEMBL | Assay Description Binding affinity to androgen receptor by fluorescence binding assay | Bioorg Med Chem Lett 20: 7516-20 (2010) Article DOI: 10.1016/j.bmcl.2010.09.140 BindingDB Entry DOI: 10.7270/Q2FJ2HR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50505997 (CHEMBL4572640) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263850 (5-[4-[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263913 (6-(4- chloro- phenyl)-5-[4- [(3S)-1-(3- fluoroprop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263919 (US9714221, Example 215) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263678 (6-(4- chloro-2- fluoro- phenyl)-5- [4-[(3S)-1- (3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263667 (US9714221, Example 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50505998 (CHEMBL4563508) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263675 (5-[4-[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263681 (6-(2,4- dichloro- phenyl)-5-[4- [(3S)-1-(3- fluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50505999 (CHEMBL4444208) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263918 (9-(4-{[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263822 (5-[4-[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263668 (6-(2- chloro-4- fluoro- phenyl)-5- [4-[(3S)-1- (3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50505995 (CHEMBL4463411) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263829 (5-[4-[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263716 (6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263920 (6-(2- Chloro-3- fluoro- phenyl)-5- {4-[(S)-1- (3-f...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263914 (6-(2- chloro- phenyl)-5-[4- [(3S)-1-(3- fluoroprop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263664 (US9714221, Example 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263674 (US9714221, Example 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263671 (6-(2- chloro-3- fluoro- phenyl)-5- [4-[(3S)-1- (3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263702 (6-(3-chloro-2-fluoro-phenyl)-5-[4-[(3S)-1-(3-fluor...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM263723 (6-(2- chlorophenyl)- 5-[4- [(3S)-1-(3- fluoropropy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
Sanofi Curated by ChEMBL | Assay Description Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu... | J Med Chem 63: 512-528 (2020) Article DOI: 10.1021/acs.jmedchem.9b01293 BindingDB Entry DOI: 10.7270/Q2154MB3 | |||||||||||
More data for this Ligand-Target Pair |
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