Compile Data Set for Download or QSAR

Found 4765 hits with Last Name = 'siliphaivanh' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449263 (CHEMBL3125333) Show SMILES OC(=O)CCCCc1nc2cc(ccc2c(=O)n1-c1ccc(F)cc1)C1=NOC2(C1)Cc1ccccc1C2 |t:28| Show InChI InChI=1S/C30H26FN3O4/c31-22-10-12-23(13-11-22)34-27(7-3-4-8-28(35)36)32-25-15-19(9-14-24(25)29(34)37)26-18-30(38-33-26)16-20-5-1-2-6-21(20)17-30/h1-2,5-6,9-15H,3-4,7-8,16-18H2,(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449259 (CHEMBL3125329) Show SMILES CCCCC1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |c:6| Show InChI InChI=1S/C32H32FN3O4/c1-2-3-19-32(23-9-5-4-6-10-23)21-28(35-40-32)22-13-18-26-27(20-22)34-29(11-7-8-12-30(37)38)36(31(26)39)25-16-14-24(33)15-17-25/h4-6,9-10,13-18,20H,2-3,7-8,11-12,19,21H2,1H3,(H,37,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449257 (CHEMBL3125327) Show SMILES CCC1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |c:4| Show InChI InChI=1S/C30H28FN3O4/c1-2-30(21-8-4-3-5-9-21)19-26(33-38-30)20-12-17-24-25(18-20)32-27(10-6-7-11-28(35)36)34(29(24)37)23-15-13-22(31)14-16-23/h3-5,8-9,12-18H,2,6-7,10-11,19H2,1H3,(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449258 (CHEMBL3125328) Show SMILES CCCC1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |c:5| Show InChI InChI=1S/C31H30FN3O4/c1-2-18-31(22-8-4-3-5-9-22)20-27(34-39-31)21-12-17-25-26(19-21)33-28(10-6-7-11-29(36)37)35(30(25)38)24-15-13-23(32)14-16-24/h3-5,8-9,12-17,19H,2,6-7,10-11,18,20H2,1H3,(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449277 (CHEMBL3125160) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1nc2ccccc2o1 |r,c:3| Show InChI InChI=1S/C30H25FN4O5/c1-30(29-33-22-6-2-3-7-25(22)39-29)17-24(34-40-30)18-10-15-21-23(16-18)32-26(8-4-5-9-27(36)37)35(28(21)38)20-13-11-19(31)12-14-20/h2-3,6-7,10-16H,4-5,8-9,17H2,1H3,(H,36,37)/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449261 (CHEMBL3125331) Show SMILES COCC1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |c:5| Show InChI InChI=1S/C30H28FN3O5/c1-38-19-30(21-7-3-2-4-8-21)18-26(33-39-30)20-11-16-24-25(17-20)32-27(9-5-6-10-28(35)36)34(29(24)37)23-14-12-22(31)13-15-23/h2-4,7-8,11-17H,5-6,9-10,18-19H2,1H3,(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449272 (CHEMBL3125342) Show SMILES C[C@@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccc(Cl)cc1 |r,c:3| Show InChI InChI=1S/C29H25ClFN3O4/c1-29(19-7-9-20(30)10-8-19)17-25(33-38-29)18-6-15-23-24(16-18)32-26(4-2-3-5-27(35)36)34(28(23)37)22-13-11-21(31)12-14-22/h6-16H,2-5,17H2,1H3,(H,35,36)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458670 (CHEMBL4212838) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1cc(Cl)ccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H26ClF3N2O5/c28-16-6-11-20-22(14-16)33(26(37)15-4-9-18(10-5-15)38-27(29,30)31)21-3-1-2-19(21)25(20)32(17-7-8-17)23(34)12-13-24(35)36/h4-6,9-11,14,17,19,21,25H,1-3,7-8,12-13H2,(H,35,36)/t19-,21+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449278 (CHEMBL3125161) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1nc2ccccc2s1 |r,c:3| Show InChI InChI=1S/C30H25FN4O4S/c1-30(29-33-22-6-2-3-7-25(22)40-29)17-24(34-39-30)18-10-15-21-23(16-18)32-26(8-4-5-9-27(36)37)35(28(21)38)20-13-11-19(31)12-14-20/h2-3,6-7,10-16H,4-5,8-9,17H2,1H3,(H,36,37)/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458673 (CHEMBL4207731) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)OCC(O)=O |r| Show InChI InChI=1S/C25H23F3N2O6/c26-25(27,28)36-16-9-5-14(6-10-16)23(33)30-19-4-2-1-3-17(19)22(18-11-12-20(18)30)29(15-7-8-15)24(34)35-13-21(31)32/h1-6,9-10,15,18,20,22H,7-8,11-13H2,(H,31,32)/t18-,20+,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449276 (CHEMBL3125159) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)[C@H](O)c1ccccc1 |r,c:3| Show InChI InChI=1S/C30H28FN3O5/c1-30(28(37)19-7-3-2-4-8-19)18-25(33-39-30)20-11-16-23-24(17-20)32-26(9-5-6-10-27(35)36)34(29(23)38)22-14-12-21(31)13-15-22/h2-4,7-8,11-17,28,37H,5-6,9-10,18H2,1H3,(H,35,36)/t28-,30+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449260 (CHEMBL3125330) Show SMILES OCC1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |c:4| Show InChI InChI=1S/C29H26FN3O5/c30-21-11-13-22(14-12-21)33-26(8-4-5-9-27(35)36)31-24-16-19(10-15-23(24)28(33)37)25-17-29(18-34,38-32-25)20-6-2-1-3-7-20/h1-3,6-7,10-16,34H,4-5,8-9,17-18H2,(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449267 (CHEMBL3125337) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccc(Cl)cc1 |r,c:3| Show InChI InChI=1S/C29H25ClFN3O4/c1-29(19-7-9-20(30)10-8-19)17-25(33-38-29)18-6-15-23-24(16-18)32-26(4-2-3-5-27(35)36)34(28(23)37)22-13-11-21(31)12-14-22/h6-16H,2-5,17H2,1H3,(H,35,36)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449255 (CHEMBL3125322) Show SMILES OC(=O)CCCCc1nc2cc(ccc2c(=O)n1-c1ccc(F)cc1)-c1cc(on1)-c1ccccc1 Show InChI InChI=1S/C28H22FN3O4/c29-20-11-13-21(14-12-20)32-26(8-4-5-9-27(33)34)30-24-16-19(10-15-22(24)28(32)35)23-17-25(36-31-23)18-6-2-1-3-7-18/h1-3,6-7,10-17H,4-5,8-9H2,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Partial agonist activity at human CRTH2 receptor expressed in HEK cells assessed as forskolin-induced cAMP formation preincubated for 10 mins followe...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458666 (CHEMBL4204359) Show SMILES OC(=O)CCC(=O)N(C1CC1)C1C2CCCC2N(C(=O)OCc2ccccc2)c2ccccc12 Show InChI InChI=1S/C27H30N2O5/c30-24(15-16-25(31)32)28(19-13-14-19)26-20-9-4-5-11-22(20)29(23-12-6-10-21(23)26)27(33)34-17-18-7-2-1-3-8-18/h1-5,7-9,11,19,21,23,26H,6,10,12-17H2,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449268 (CHEMBL3125338) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1cccc(c1)C#N |r,c:3| Show InChI InChI=1S/C30H25FN4O4/c1-30(21-6-4-5-19(15-21)18-32)17-26(34-39-30)20-9-14-24-25(16-20)33-27(7-2-3-8-28(36)37)35(29(24)38)23-12-10-22(31)11-13-23/h4-6,9-16H,2-3,7-8,17H2,1H3,(H,36,37)/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458667 (CHEMBL4207935) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1cc(F)ccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H26F4N2O5/c28-16-6-11-20-22(14-16)33(26(37)15-4-9-18(10-5-15)38-27(29,30)31)21-3-1-2-19(21)25(20)32(17-7-8-17)23(34)12-13-24(35)36/h4-6,9-11,14,17,19,21,25H,1-3,7-8,12-13H2,(H,35,36)/t19-,21+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458672 (CHEMBL4203572) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1cc(Cl)c(F)cc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H25ClF4N2O5/c28-19-13-22-18(12-20(19)29)25(33(15-6-7-15)23(35)10-11-24(36)37)17-2-1-3-21(17)34(22)26(38)14-4-8-16(9-5-14)39-27(30,31)32/h4-5,8-9,12-13,15,17,21,25H,1-3,6-7,10-11H2,(H,36,37)/t17-,21+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449266 (CHEMBL3125336) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1cc(F)cc(F)c1 |r,c:3| Show InChI InChI=1S/C29H24F3N3O4/c1-29(18-13-20(31)15-21(32)14-18)16-25(34-39-29)17-6-11-23-24(12-17)33-26(4-2-3-5-27(36)37)35(28(23)38)22-9-7-19(30)8-10-22/h6-15H,2-5,16H2,1H3,(H,36,37)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458652 (CHEMBL4202859) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1ccc(F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)OCC(O)=O |r| Show InChI InChI=1S/C24H23FN2O5/c25-15-7-5-14(6-8-15)23(30)27-19-4-2-1-3-17(19)22(18-11-12-20(18)27)26(16-9-10-16)24(31)32-13-21(28)29/h1-8,16,18,20,22H,9-13H2,(H,28,29)/t18-,20+,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449264 (CHEMBL3125334) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |r,c:3| Show InChI InChI=1S/C29H26FN3O4/c1-29(20-7-3-2-4-8-20)18-25(32-37-29)19-11-16-23-24(17-19)31-26(9-5-6-10-27(34)35)33(28(23)36)22-14-12-21(30)13-15-22/h2-4,7-8,11-17H,5-6,9-10,18H2,1H3,(H,34,35)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449275 (CHEMBL3125158) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)[C@@H](O)c1ccccc1 |r,c:3| Show InChI InChI=1S/C30H28FN3O5/c1-30(28(37)19-7-3-2-4-8-19)18-25(33-39-30)20-11-16-23-24(17-20)32-26(9-5-6-10-27(35)36)34(29(23)38)22-14-12-21(31)13-15-22/h2-4,7-8,11-17,28,37H,5-6,9-10,18H2,1H3,(H,35,36)/t28-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458681 (CHEMBL4215576) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C26H25F3N2O5/c27-26(28,29)36-17-9-5-15(6-10-17)25(35)31-20-4-2-1-3-18(20)24(19-11-12-21(19)31)30(16-7-8-16)22(32)13-14-23(33)34/h1-6,9-10,16,19,21,24H,7-8,11-14H2,(H,33,34)/t19-,21+,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449265 (CHEMBL3125335) Show SMILES C[C@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccc(F)cc1 |r,c:3| Show InChI InChI=1S/C29H25F2N3O4/c1-29(19-7-9-20(30)10-8-19)17-25(33-38-29)18-6-15-23-24(16-18)32-26(4-2-3-5-27(35)36)34(28(23)37)22-13-11-21(31)12-14-22/h6-16H,2-5,17H2,1H3,(H,35,36)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458677 (CHEMBL4212084) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1cccc(F)c1)c1ccccc1[C@@H]2N(C1CC1)C(=O)OCC(O)=O |r| Show InChI InChI=1S/C24H23FN2O5/c25-15-5-3-4-14(12-15)23(30)27-19-7-2-1-6-17(19)22(18-10-11-20(18)27)26(16-8-9-16)24(31)32-13-21(28)29/h1-7,12,16,18,20,22H,8-11,13H2,(H,28,29)/t18-,20+,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449256 (CHEMBL3125326) Show SMILES CC1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccccc1 |c:3| Show InChI InChI=1S/C29H26FN3O4/c1-29(20-7-3-2-4-8-20)18-25(32-37-29)19-11-16-23-24(17-19)31-26(9-5-6-10-27(34)35)33(28(23)36)22-14-12-21(30)13-15-22/h2-4,7-8,11-17H,5-6,9-10,18H2,1H3,(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458663 (CHEMBL4208457) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccc(F)cc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H26F4N2O5/c28-16-6-11-22-20(14-16)25(32(17-7-8-17)23(34)12-13-24(35)36)19-2-1-3-21(19)33(22)26(37)15-4-9-18(10-5-15)38-27(29,30)31/h4-6,9-11,14,17,19,21,25H,1-3,7-8,12-13H2,(H,35,36)/t19-,21+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458669 (CHEMBL4215049) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1cccc(OC(F)(F)F)c1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C26H25F3N2O5/c27-26(28,29)36-17-5-3-4-15(14-17)25(35)31-20-7-2-1-6-18(20)24(19-10-11-21(19)31)30(16-8-9-16)22(32)12-13-23(33)34/h1-7,14,16,19,21,24H,8-13H2,(H,33,34)/t19-,21+,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449283 (CHEMBL3125321) Show SMILES C[C@@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1nc2ccccc2s1 |r,c:3| Show InChI InChI=1S/C30H25FN4O4S/c1-30(29-33-22-6-2-3-7-25(22)40-29)17-24(34-39-30)18-10-15-21-23(16-18)32-26(8-4-5-9-27(36)37)35(28(21)38)20-13-11-19(31)12-14-20/h2-3,6-7,10-16H,4-5,8-9,17H2,1H3,(H,36,37)/t30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458688 (CHEMBL4213245) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)O[C@@H](C)c1ccc(F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C28H31FN2O5/c1-17(18-9-11-19(29)12-10-18)36-28(35)31-23-7-3-2-5-21(23)27(22-6-4-8-24(22)31)30(20-13-14-20)25(32)15-16-26(33)34/h2-3,5,7,9-12,17,20,22,24,27H,4,6,8,13-16H2,1H3,(H,33,34)/t17-,22+,24-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449270 (CHEMBL3125340) Show SMILES C[C@@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccc(F)cc1 |r,c:3| Show InChI InChI=1S/C29H25F2N3O4/c1-29(19-7-9-20(30)10-8-19)17-25(33-38-29)18-6-15-23-24(16-18)32-26(4-2-3-5-27(35)36)34(28(23)37)22-13-11-21(31)12-14-22/h6-16H,2-5,17H2,1H3,(H,35,36)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458683 (CHEMBL4203786) Show SMILES [H][C@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H27F3N2O5/c28-27(29,30)37-18-12-8-16(9-13-18)26(36)32-21-6-2-1-4-19(21)25(20-5-3-7-22(20)32)31(17-10-11-17)23(33)14-15-24(34)35/h1-2,4,6,8-9,12-13,17,20,22,25H,3,5,7,10-11,14-15H2,(H,34,35)/t20-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458671 (CHEMBL4210620) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1ccc(F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C25H25FN2O4/c26-16-7-5-15(6-8-16)25(32)28-20-4-2-1-3-18(20)24(19-11-12-21(19)28)27(17-9-10-17)22(29)13-14-23(30)31/h1-8,17,19,21,24H,9-14H2,(H,30,31)/t19-,21+,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449279 (CHEMBL3125162) Show SMILES C[C@]1(Cc2ccccc2)CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O |r,c:11| Show InChI InChI=1S/C30H28FN3O4/c1-30(18-20-7-3-2-4-8-20)19-26(33-38-30)21-11-16-24-25(17-21)32-27(9-5-6-10-28(35)36)34(29(24)37)23-14-12-22(31)13-15-23/h2-4,7-8,11-17H,5-6,9-10,18-19H2,1H3,(H,35,36)/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449274 (CHEMBL3125157) Show SMILES C[C@@]1(Cc2ccccc2)CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O |r,c:11| Show InChI InChI=1S/C30H28FN3O4/c1-30(18-20-7-3-2-4-8-20)19-26(33-38-30)21-11-16-24-25(17-21)32-27(9-5-6-10-28(35)36)34(29(24)37)23-14-12-22(31)13-15-23/h2-4,7-8,11-17H,5-6,9-10,18-19H2,1H3,(H,35,36)/t30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458659 (CHEMBL4203383) Show SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1cccc(F)c1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C25H25FN2O4/c26-16-5-3-4-15(14-16)25(32)28-20-7-2-1-6-18(20)24(19-10-11-21(19)28)27(17-8-9-17)22(29)12-13-23(30)31/h1-7,14,17,19,21,24H,8-13H2,(H,30,31)/t19-,21+,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458690 (CHEMBL4205047) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(SC(F)(F)F)cc1)c1ccc(F)cc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H26F4N2O4S/c28-16-6-11-22-20(14-16)25(32(17-7-8-17)23(34)12-13-24(35)36)19-2-1-3-21(19)33(22)26(37)15-4-9-18(10-5-15)38-27(29,30)31/h4-6,9-11,14,17,19,21,25H,1-3,7-8,12-13H2,(H,35,36)/t19-,21+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458684 (CHEMBL4203284) Show SMILES [H][C@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(C1CCC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C28H29F3N2O5/c29-28(30,31)38-19-13-11-17(12-14-19)27(37)33-22-9-2-1-7-20(22)26(21-8-4-10-23(21)33)32(18-5-3-6-18)24(34)15-16-25(35)36/h1-2,7,9,11-14,18,21,23,26H,3-6,8,10,15-16H2,(H,35,36)/t21-,23-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458674 (CHEMBL4212522) Show SMILES [H][C@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(CC1CCC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C29H31F3N2O5/c30-29(31,32)39-20-13-11-19(12-14-20)28(38)34-23-9-2-1-7-21(23)27(22-8-4-10-24(22)34)33(17-18-5-3-6-18)25(35)15-16-26(36)37/h1-2,7,9,11-14,18,22,24,27H,3-6,8,10,15-17H2,(H,36,37)/t22-,24-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458680 (CHEMBL4205802) Show SMILES OC(=O)COC(=O)N(C1CC1)C1C2CCCC2N(C(=O)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H26N2O5/c28-22(29)15-32-25(31)26(17-13-14-17)23-18-9-4-5-11-20(18)27(21-12-6-10-19(21)23)24(30)16-7-2-1-3-8-16/h1-5,7-9,11,17,19,21,23H,6,10,12-15H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458668 (CHEMBL4217503) Show SMILES OC(=O)CCC(=O)N(C1CC1)C1C2CCCC2N(C(=O)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H28N2O4/c29-23(15-16-24(30)31)27(18-13-14-18)25-19-9-4-5-11-21(19)28(22-12-6-10-20(22)25)26(32)17-7-2-1-3-8-17/h1-5,7-9,11,18,20,22,25H,6,10,12-16H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449271 (CHEMBL3125341) Show SMILES C[C@@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1cc(F)cc(F)c1 |r,c:3| Show InChI InChI=1S/C29H24F3N3O4/c1-29(18-13-20(31)15-21(32)14-18)16-25(34-39-29)17-6-11-23-24(12-17)33-26(4-2-3-5-27(36)37)35(28(23)38)22-9-7-19(30)8-10-22/h6-15H,2-5,16H2,1H3,(H,36,37)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458675 (CHEMBL4207202) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)OCc1ccc(F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C27H29FN2O5/c28-18-10-8-17(9-11-18)16-35-27(34)30-22-6-2-1-4-20(22)26(21-5-3-7-23(21)30)29(19-12-13-19)24(31)14-15-25(32)33/h1-2,4,6,8-11,19,21,23,26H,3,5,7,12-16H2,(H,32,33)/t21-,23+,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458657 (CHEMBL4216012) Show SMILES [H][C@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(CC)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C26H27F3N2O5/c1-2-30(22(32)14-15-23(33)34)24-18-6-3-4-8-20(18)31(21-9-5-7-19(21)24)25(35)16-10-12-17(13-11-16)36-26(27,28)29/h3-4,6,8,10-13,19,21,24H,2,5,7,9,14-15H2,1H3,(H,33,34)/t19-,21-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458664 (CHEMBL4216735) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccc(cc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O)C(F)F |r| Show InChI InChI=1S/C28H27F5N2O5/c29-26(30)16-6-11-22-20(14-16)25(34(17-7-8-17)23(36)12-13-24(37)38)19-2-1-3-21(19)35(22)27(39)15-4-9-18(10-5-15)40-28(31,32)33/h4-6,9-11,14,17,19,21,25-26H,1-3,7-8,12-13H2,(H,37,38)/t19-,21+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449262 (CHEMBL3125332) Show SMILES OC(=O)CCCCc1nc2cc(ccc2c(=O)n1-c1ccc(F)cc1)C1=NOC(C1)(c1ccccc1)c1ccccc1 |t:28| Show InChI InChI=1S/C34H28FN3O4/c35-26-16-18-27(19-17-26)38-31(13-7-8-14-32(39)40)36-29-21-23(15-20-28(29)33(38)41)30-22-34(42-37-30,24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-6,9-12,15-21H,7-8,13-14,22H2,(H,39,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458687 (CHEMBL4208314) Show SMILES [H][C@@]12CCC[C@]1([H])N(C(=O)O[C@H](C)c1ccc(F)cc1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C28H31FN2O5/c1-17(18-9-11-19(29)12-10-18)36-28(35)31-23-7-3-2-5-21(23)27(22-6-4-8-24(22)31)30(20-13-14-20)25(32)15-16-26(33)34/h2-3,5,7,9-12,17,20,22,24,27H,4,6,8,13-16H2,1H3,(H,33,34)/t17-,22-,24+,27+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50458682 (CHEMBL4211054) Show SMILES [H][C@]12CCC[C@]1([H])N(C(=O)c1ccc(OC(F)(F)F)cc1)c1ccccc1[C@@H]2N(C)C(=O)CCC(O)=O |r| Show InChI InChI=1S/C25H25F3N2O5/c1-29(21(31)13-14-22(32)33)23-17-5-2-3-7-19(17)30(20-8-4-6-18(20)23)24(34)15-9-11-16(12-10-15)35-25(26,27)28/h2-3,5,7,9-12,18,20,23H,4,6,8,13-14H2,1H3,(H,32,33)/t18-,20-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting method				ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449281 (CHEMBL3125319) Show SMILES C[C@@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)[C@H](O)c1ccccc1 |r,c:3| Show InChI InChI=1S/C30H28FN3O5/c1-30(28(37)19-7-3-2-4-8-19)18-25(33-39-30)20-11-16-23-24(17-20)32-26(9-5-6-10-27(35)36)34(29(23)38)22-14-12-21(31)13-15-22/h2-4,7-8,11-17,28,37H,5-6,9-10,18H2,1H3,(H,35,36)/t28-,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50449282 (CHEMBL3125320) Show SMILES C[C@@]1(CC(=NO1)c1ccc2c(c1)nc(CCCCC(O)=O)n(-c1ccc(F)cc1)c2=O)c1nc2ccccc2o1 |r,c:3| Show InChI InChI=1S/C30H25FN4O5/c1-30(29-33-22-6-2-3-7-25(22)39-29)17-24(34-40-30)18-10-15-21-23(16-18)32-26(8-4-5-9-27(36)37)35(28(21)38)20-13-11-19(31)12-14-20/h2-3,6-7,10-16H,4-5,8-9,17H2,1H3,(H,36,37)/t30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...				Bioorg Med Chem Lett 24: 1615-20 (2014) Article DOI: 10.1016/j.bmcl.2014.01.043 BindingDB Entry DOI: 10.7270/Q2JQ12G9
					More data for this Ligand-Target Pair

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