Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50063555 (1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards thrombin | J Med Chem 41: 1011-3 (1998) Article DOI: 10.1021/jm9706933 BindingDB Entry DOI: 10.7270/Q2ZG6RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50060708 ((S)-1-(3-Benzo[1,3]dioxol-5-yl-3-pyridin-3-yl-prop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | 2.51E+3 | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Thrombin | J Med Chem 40: 3687-93 (1997) Article DOI: 10.1021/jm970397q BindingDB Entry DOI: 10.7270/Q20Z73ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484029 (CHEMBL1801258) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484039 (CHEMBL1800087) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066331 ((S)-1-[(R)-2-Cyclohexyl-2-(diethylcarbamoylmethyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484030 (CHEMBL1801256) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066338 (CHEMBL327115 | [2-({[(S)-1-((R)-2-Amino-2-cyclohex...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484030 (CHEMBL1801256) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484045 (CHEMBL1801257) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484045 (CHEMBL1801257) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066332 ((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484030 (CHEMBL1801256) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484029 (CHEMBL1801258) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066333 ((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484031 (CHEMBL1801255) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484029 (CHEMBL1801258) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484040 (CHEMBL1801228) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484045 (CHEMBL1801257) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484032 (CHEMBL1801231) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066334 ((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484022 (CHEMBL1801223) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484023 (CHEMBL1801230) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484039 (CHEMBL1800087) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484024 (CHEMBL1801227) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50060705 ((S)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Thrombin | J Med Chem 40: 3687-93 (1997) Article DOI: 10.1021/jm970397q BindingDB Entry DOI: 10.7270/Q20Z73ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484035 (CHEMBL1801266) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484043 (CHEMBL1801262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484022 (CHEMBL1801223) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066340 ((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484026 (CHEMBL1801225) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066337 ((S)-1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50060704 ((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Thrombin | J Med Chem 40: 3687-93 (1997) Article DOI: 10.1021/jm970397q BindingDB Entry DOI: 10.7270/Q20Z73ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50063562 (1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards thrombin | J Med Chem 41: 1011-3 (1998) Article DOI: 10.1021/jm9706933 BindingDB Entry DOI: 10.7270/Q2ZG6RCF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484040 (CHEMBL1801228) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484033 (CHEMBL1801229) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50060703 ((S)-1-(3-Phenyl-3-pyridin-4-yl-propionyl)-pyrrolid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | 1.55E+3 | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Thrombin | J Med Chem 40: 3687-93 (1997) Article DOI: 10.1021/jm970397q BindingDB Entry DOI: 10.7270/Q20Z73ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484031 (CHEMBL1801255) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484040 (CHEMBL1801228) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484032 (CHEMBL1801231) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484035 (CHEMBL1801266) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484024 (CHEMBL1801227) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484032 (CHEMBL1801231) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484036 (CHEMBL1801265) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50066336 ((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated on serine protease thrombin. | J Med Chem 41: 3210-9 (1998) Article DOI: 10.1021/jm9801713 BindingDB Entry DOI: 10.7270/Q24Q7T4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484028 (CHEMBL1801263) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484023 (CHEMBL1801230) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50484041 (CHEMBL1801254) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50484026 (CHEMBL1801225) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 20: 4328-32 (2010) Article DOI: 10.1016/j.bmcl.2010.06.083 BindingDB Entry DOI: 10.7270/Q2TH8QJ4 | |||||||||||
More data for this Ligand-Target Pair |
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