BindingDB PrimarySearch

Found 28 hits with Last Name = 'smith' and Initial = 'pj'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Falcipain-2 (Plasmodium falciparum)	BDBM50157741 (CHEMBL374508 \| E-64 \| E64) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415544 (CHEMBL597626) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147398 (2-[2,4']Bibenzooxazolyl-2'-yl-phenol \| CHEMBL32395...) Show SMILES Oc1ccccc1-c1nc2c(cccc2o1)-c1nc2ccccc2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147398 (2-[2,4']Bibenzooxazolyl-2'-yl-phenol \| CHEMBL32395...) Show SMILES Oc1ccccc1-c1nc2c(cccc2o1)-c1nc2ccccc2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147399 (2'-(2-Hydroxy-phenyl)-[2,4']bibenzooxazolyl-4-carb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Chloroquine resistance transporter (Plasmodium falciparum)	BDBM50353744 (CHEMBL1830986) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi...				J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147400 (2'-Phenyl-[2,4']bibenzooxazolyl-4-carboxylic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147399 (2'-(2-Hydroxy-phenyl)-[2,4']bibenzooxazolyl-4-carb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Chloroquine resistance transporter (Plasmodium falciparum)	BDBM50353743 (CHEMBL1830985) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi...				J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Chloroquine resistance transporter (Plasmodium falciparum)	BDBM50353745 (CHEMBL1830987) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi...				J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415541 (CHEMBL597017) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415542 (CHEMBL602103) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415543 (CHEMBL589510) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(OCC#C)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415545 (CHEMBL597625) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415546 (CHEMBL597624) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1cccc(OCC#C)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415547 (CHEMBL597896) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415548 (CHEMBL589509) Show SMILES COc1ccc(C(=O)\C=C\c2ccccc2OCC#C)c(OC)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415540 (CHEMBL597219) Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2OCC#C)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415539 (CHEMBL597220) Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2OCC#C)c(OC)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415538 (CHEMBL596610) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415537 (CHEMBL596611) Show SMILES COc1ccc(\C=C\C(=O)c2cccc(OCC#C)c2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415536 (CHEMBL589903) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415549 (CHEMBL597892) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1OCC#C Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415534 (CHEMBL606235) Show SMILES COc1ccc(\C=C\C(=O)c2ccc(OCC#C)cc2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415533 (CHEMBL592268) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415532 (CHEMBL592303) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147401 (2'-Phenyl-[2,4']bibenzooxazolyl \| CHEMBL113081) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activity				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50415535 (CHEMBL589904) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum falcipain-2				Bioorg Med Chem Lett 20: 942-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.062 BindingDB Entry DOI: 10.7270/Q26M383G
University of Cape Town Curated by ChEMBL					More data for this Ligand-Target Pair