Compile Data Set for Download or QSAR

Found 595 hits with Last Name = 'sohn' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical R & D, Astra Arcus AB Curated by PDSP Ki Database									J Pharmacol Exp Ther 283: 216-25 (1997) BindingDB Entry DOI: 10.7270/Q22Z142T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM85190 (CAS_3055171 | NAD-299 | NSC_3055171) Show SMILES NC(=O)c1ccc(F)c2OCC(Cc12)N(C1CCC1)C1CCC1 Show InChI InChI=1S/C18H23FN2O2/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12/h7-8,11-13H,1-6,9-10H2,(H2,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical R & D, Astra Arcus AB Curated by PDSP Ki Database									J Pharmacol Exp Ther 283: 216-25 (1997) BindingDB Entry DOI: 10.7270/Q22Z142T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI InChI=1S/C22H29N/c1-3-15-23(16-4-2)20-13-14-22-19(17-20)11-8-12-21(22)18-9-6-5-7-10-18/h5-12,20H,3-4,13-17H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150676 (((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1 Show InChI InChI=1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150678 (CHEMBL186758 | [(R)-8-(4-Methoxy-phenyl)-chroman-3...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccc(OC)cc1 Show InChI InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)19-15-18-7-6-8-21(22(18)25-16-19)17-9-11-20(24-3)12-10-17/h6-12,19H,4-5,13-16H2,1-3H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150677 (CHEMBL188176 | [(S)-5-(4-Methoxy-phenyl)-1,2,3,4-t...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccc(OC)cc1 Show InChI InChI=1S/C23H31NO/c1-4-15-24(16-5-2)20-11-14-23-19(17-20)7-6-8-22(23)18-9-12-21(25-3)13-10-18/h6-10,12-13,20H,4-5,11,14-17H2,1-3H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150680 (CHEMBL184535 | [(S)-5-(2-Methoxy-phenyl)-1,2,3,4-t...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1OC Show InChI InChI=1S/C23H31NO/c1-4-15-24(16-5-2)19-13-14-20-18(17-19)9-8-11-21(20)22-10-6-7-12-23(22)25-3/h6-12,19H,4-5,13-17H2,1-3H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150681 (4-(4-Chloro-phenoxy)-1-{2-[(R)-1-(3H-indene-5-sulf...) Show SMILES Clc1ccc(OC2CCN(CC[C@H]3CCCN3S(=O)(=O)c3ccc4C=CCc4c3)CC2)cc1 |c:25| Show InChI InChI=1S/C26H31ClN2O3S/c27-22-7-9-24(10-8-22)32-25-13-17-28(18-14-25)16-12-23-5-2-15-29(23)33(30,31)26-11-6-20-3-1-4-21(20)19-26/h1,3,6-11,19,23,25H,2,4-5,12-18H2/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Fc1ccc2n(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)c(=O)[nH]c2c1 Show InChI InChI=1S/C24H27FN4O2/c25-18-7-8-22-21(16-18)26-24(31)29(22)19-9-12-27(13-10-19)14-15-28-11-3-5-17-4-1-2-6-20(17)23(28)30/h1-2,4,6-8,16,19H,3,5,9-15H2,(H,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150673 (CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](CCc12)N(C)C |wD:16.22,(2.58,2.38,;1.26,1.59,;-.09,2.35,;-.11,3.87,;-1.44,4.65,;-2.77,3.85,;-2.75,2.31,;-4.09,1.52,;-4.07,-.02,;-1.42,1.56,;-1.42,.02,;-2.73,-.76,;-2.73,-2.3,;-1.42,-3.07,;-.09,-2.3,;1.25,-3.07,;2.58,-2.32,;2.58,-.78,;1.25,.02,;-.09,-.76,;4.08,-2.72,;4.29,-4.24,;5.24,-1.69,)| Show InChI InChI=1S/C20H25NO2/c1-21(2)15-11-12-16-14(13-15)7-5-8-17(16)20-18(22-3)9-6-10-19(20)23-4/h5-10,15H,11-13H2,1-4H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150673 (CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](CCc12)N(C)C |wD:16.22,(2.58,2.38,;1.26,1.59,;-.09,2.35,;-.11,3.87,;-1.44,4.65,;-2.77,3.85,;-2.75,2.31,;-4.09,1.52,;-4.07,-.02,;-1.42,1.56,;-1.42,.02,;-2.73,-.76,;-2.73,-2.3,;-1.42,-3.07,;-.09,-2.3,;1.25,-3.07,;2.58,-2.32,;2.58,-.78,;1.25,.02,;-.09,-.76,;4.08,-2.72,;4.29,-4.24,;5.24,-1.69,)| Show InChI InChI=1S/C20H25NO2/c1-21(2)15-11-12-16-14(13-15)7-5-8-17(16)20-18(22-3)9-6-10-19(20)23-4/h5-10,15H,11-13H2,1-4H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-HT7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150679 (CHEMBL186316 | [(R)-8-(2-Methoxy-phenyl)-chroman-3...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1OC Show InChI InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)18-15-17-9-8-11-20(22(17)25-16-18)19-10-6-7-12-21(19)24-3/h6-12,18H,4-5,13-16H2,1-3H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150676 (((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1 Show InChI InChI=1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI InChI=1S/C22H29N/c1-3-15-23(16-4-2)20-13-14-22-19(17-20)11-8-12-21(22)18-9-6-5-7-10-18/h5-12,20H,3-4,13-17H2,1-2H3/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50098549 ((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 |wD:10.11,(21.5,-8.8,;21.5,-7.27,;22.84,-6.51,;22.87,-4.98,;21.53,-4.21,;21.56,-2.65,;20.23,-1.86,;18.86,-2.62,;18.86,-4.18,;20.19,-4.98,;20.19,-6.51,;18.86,-7.27,;17.55,-6.51,;16.21,-7.27,;14.91,-6.51,;14.91,-4.98,;16.21,-4.18,;16.18,-2.49,;14.78,-1.86,;13.54,-2.72,;14.66,-.33,;15.93,.56,;17.3,-.11,;17.42,-1.63,;18.76,-.84,;20.07,-.07,;17.55,-4.95,)| Show InChI InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432452 (CHEMBL2349310) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2ccccc2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H25N5OS2/c1-11(2)9-14(10-25)21-16-15-17(22-18(20)27-15)24-19(23-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,25H,9-10H2,1-3H3,(H3,20,21,22,23,24)/t12-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432439 (CHEMBL2349322) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2Br)nc2nc(N)sc12 |r| Show InChI InChI=1S/C18H22BrN5OS2/c1-10(2)7-12(8-25)21-15-14-16(22-17(20)27-14)24-18(23-15)26-9-11-5-3-4-6-13(11)19/h3-6,10,12,25H,7-9H2,1-2H3,(H3,20,21,22,23,24)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50432427 (CHEMBL2349306) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C18H20F2N4O2S2/c1-9(2)6-11(7-25)21-15-14-16(24-18(26)28-14)23-17(22-15)27-8-10-4-3-5-12(19)13(10)20/h3-5,9,11,25H,6-8H2,1-2H3,(H2,21,22,23,24,26)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432471 (CHEMBL2349316) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2ccccc2F)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H24FN5OS2/c1-10(2)8-12(9-26)22-16-15-17(23-18(21)28-15)25-19(24-16)27-11(3)13-6-4-5-7-14(13)20/h4-7,10-12,26H,8-9H2,1-3H3,(H3,21,22,23,24,25)/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150684 ((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C |wD:16.22,(-5.36,2.24,;-4,1.49,;-2.67,2.28,;-2.7,3.82,;-1.37,4.59,;,3.84,;,2.29,;1.31,1.53,;2.64,2.29,;-1.34,1.53,;-1.34,-.01,;-2.67,-.78,;-2.67,-2.32,;-1.34,-3.09,;,-2.34,;1.31,-3.13,;2.67,-2.34,;2.67,-.78,;1.31,-.01,;,-.78,;4,-3.13,;4,-4.66,;5.35,-2.34,)| Show InChI InChI=1S/C19H23NO3/c1-20(2)14-11-13-7-5-8-15(19(13)23-12-14)18-16(21-3)9-6-10-17(18)22-4/h5-10,14H,11-12H2,1-4H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432466 (CHEMBL2349180) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2cc(Cl)ccn2)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C18H22ClN5O2S2/c1-9(2)6-12(8-25)21-15-14-16(24-18(26)28-14)23-17(22-15)27-10(3)13-7-11(19)4-5-20-13/h4-5,7,9-10,12,25H,6,8H2,1-3H3,(H2,21,22,23,24,26)/t10-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432467 (CHEMBL2349179) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2cc(Cl)ccn2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C18H23ClN6OS2/c1-9(2)6-12(8-26)22-15-14-16(23-17(20)28-14)25-18(24-15)27-10(3)13-7-11(19)4-5-21-13/h4-5,7,9-10,12,26H,6,8H2,1-3H3,(H3,20,22,23,24,25)/t10-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150686 (CHEMBL182792 | [(R)-8-(2,6-Dimethoxy-phenyl)-chrom...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1c(OC)cccc1OC |wD:7.6,(1.92,-6.31,;1.94,-4.77,;3.27,-4,;3.27,-2.46,;4.6,-1.69,;5.93,-2.46,;7.28,-1.69,;1.94,-1.68,;1.94,-.12,;.58,.65,;-.75,-.12,;-.75,-1.68,;.58,-2.46,;-2.08,-2.43,;-3.41,-1.66,;-3.41,-.12,;-2.08,.65,;-2.09,2.19,;-.76,2.96,;.58,2.19,;1.91,2.96,;-.76,4.5,;-2.1,5.27,;-3.45,4.47,;-3.42,2.94,;-4.75,2.16,;-6.09,2.92,)| Show InChI InChI=1S/C23H31NO3/c1-5-13-24(14-6-2)18-15-17-9-7-10-19(23(17)27-16-18)22-20(25-3)11-8-12-21(22)26-4/h7-12,18H,5-6,13-16H2,1-4H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150682 (2a-[4-(6,7-Dihydro-4H-thieno[3,2-c]pyridin-5-yl)-b...) Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCc4sccc4C1)c23 Show InChI InChI=1S/C22H26N2OS/c25-21-22(11-4-6-16-5-3-7-18(23-21)20(16)22)10-1-2-12-24-13-8-19-17(15-24)9-14-26-19/h3,5,7,9,14H,1-2,4,6,8,10-13,15H2,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432450 (CHEMBL2349312) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2ccccc2)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C19H24N4O2S2/c1-11(2)9-14(10-24)20-16-15-17(23-19(25)27-15)22-18(21-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,24H,9-10H2,1-3H3,(H2,20,21,22,23,25)/t12-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150674 (CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1c(OC)cccc1OC |wD:7.6,(2.5,-6.14,;2.29,-4.62,;3.51,-3.66,;3.3,-2.15,;4.44,-1.12,;5.91,-1.61,;7.07,-.59,;1.8,-1.75,;1.8,-.22,;.47,.58,;-.86,-.17,;-.86,-1.73,;.47,-2.5,;-2.18,-2.5,;-3.49,-1.73,;-3.49,-.17,;-2.18,.58,;-2.18,2.12,;-3.51,2.87,;-4.85,2.09,;-4.83,.54,;-3.56,4.41,;-2.21,5.19,;-.88,4.43,;-.86,2.92,;.47,2.16,;1.8,2.95,)| Show InChI InChI=1S/C24H33NO2/c1-5-15-25(16-6-2)19-13-14-20-18(17-19)9-7-10-21(20)24-22(26-3)11-8-12-23(24)27-4/h7-12,19H,5-6,13-17H2,1-4H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-HT7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150674 (CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1c(OC)cccc1OC |wD:7.6,(2.5,-6.14,;2.29,-4.62,;3.51,-3.66,;3.3,-2.15,;4.44,-1.12,;5.91,-1.61,;7.07,-.59,;1.8,-1.75,;1.8,-.22,;.47,.58,;-.86,-.17,;-.86,-1.73,;.47,-2.5,;-2.18,-2.5,;-3.49,-1.73,;-3.49,-.17,;-2.18,.58,;-2.18,2.12,;-3.51,2.87,;-4.85,2.09,;-4.83,.54,;-3.56,4.41,;-2.21,5.19,;-.88,4.43,;-.86,2.92,;.47,2.16,;1.8,2.95,)| Show InChI InChI=1S/C24H33NO2/c1-5-15-25(16-6-2)19-13-14-20-18(17-19)9-7-10-21(20)24-22(26-3)11-8-12-23(24)27-4/h7-12,19H,5-6,13-17H2,1-4H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432449 (CHEMBL2349313) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@H](C)c2ccccc2)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C19H24N4O2S2/c1-11(2)9-14(10-24)20-16-15-17(23-19(25)27-15)22-18(21-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,24H,9-10H2,1-3H3,(H2,20,21,22,23,25)/t12-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432429 (CHEMBL2349332) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2ccc(Br)cc2F)nc2nc(N)sc12 |r| Show InChI InChI=1S/C18H21BrFN5OS2/c1-9(2)5-12(7-26)22-15-14-16(23-17(21)28-14)25-18(24-15)27-8-10-3-4-11(19)6-13(10)20/h3-4,6,9,12,26H,5,7-8H2,1-2H3,(H3,21,22,23,24,25)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432455 (CHEMBL2349303) Show SMILES COC(=O)[C@@H](CC(C)C)Nc1nc(SCc2ccccc2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H23N5O2S2/c1-11(2)9-13(17(25)26-3)21-15-14-16(22-18(20)28-14)24-19(23-15)27-10-12-7-5-4-6-8-12/h4-8,11,13H,9-10H2,1-3H3,(H3,20,21,22,23,24)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432427 (CHEMBL2349306) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C18H20F2N4O2S2/c1-9(2)6-11(7-25)21-15-14-16(24-18(26)28-14)23-17(22-15)27-8-10-4-3-5-12(19)13(10)20/h3-5,9,11,25H,6-8H2,1-2H3,(H2,21,22,23,24,26)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150679 (CHEMBL186316 | [(R)-8-(2-Methoxy-phenyl)-chroman-3...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1OC Show InChI InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)18-15-17-9-8-11-20(22(17)25-16-18)19-10-6-7-12-21(19)24-3/h6-12,18H,4-5,13-16H2,1-3H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150680 (CHEMBL184535 | [(S)-5-(2-Methoxy-phenyl)-1,2,3,4-t...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1OC Show InChI InChI=1S/C23H31NO/c1-4-15-24(16-5-2)19-13-14-20-18(17-19)9-8-11-21(20)22-10-6-7-12-23(22)25-3/h6-12,19H,4-5,13-17H2,1-3H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150677 (CHEMBL188176 | [(S)-5-(4-Methoxy-phenyl)-1,2,3,4-t...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccc(OC)cc1 Show InChI InChI=1S/C23H31NO/c1-4-15-24(16-5-2)20-11-14-23-19(17-20)7-6-8-22(23)18-9-12-21(25-3)13-10-18/h6-10,12-13,20H,4-5,11,14-17H2,1-3H3/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50150678 (CHEMBL186758 | [(R)-8-(4-Methoxy-phenyl)-chroman-3...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccc(OC)cc1 Show InChI InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)19-15-18-7-6-8-21(22(18)25-16-19)17-9-11-20(24-3)12-10-17/h6-12,19H,4-5,13-16H2,1-3H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432460 (CHEMBL2349314) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2ccccc2Br)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H24BrN5OS2/c1-10(2)8-12(9-26)22-16-15-17(23-18(21)28-15)25-19(24-16)27-11(3)13-6-4-5-7-14(13)20/h4-7,10-12,26H,8-9H2,1-3H3,(H3,21,22,23,24,25)/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432469 (CHEMBL2349318) Show SMILES CCC[C@H](CO)Nc1nc(S[C@@H](C)c2cccc(c2)C#N)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C19H21N5O2S2/c1-3-5-14(10-25)21-16-15-17(24-19(26)28-15)23-18(22-16)27-11(2)13-7-4-6-12(8-13)9-20/h4,6-8,11,14,25H,3,5,10H2,1-2H3,(H2,21,22,23,24,26)/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432451 (CHEMBL2349311) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@H](C)c2ccccc2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H25N5OS2/c1-11(2)9-14(10-25)21-16-15-17(22-18(20)27-15)24-19(23-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,25H,9-10H2,1-3H3,(H3,20,21,22,23,24)/t12-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432464 (CHEMBL2349182) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCCc2ccccc2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H25N5OS2/c1-12(2)10-14(11-25)21-16-15-17(22-18(20)27-15)24-19(23-16)26-9-8-13-6-4-3-5-7-13/h3-7,12,14,25H,8-11H2,1-2H3,(H3,20,21,22,23,24)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432465 (CHEMBL2349181) Show SMILES CCC[C@H](CO)Nc1nc(S[C@@H](C)c2cnccc2Cl)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C17H20ClN5O2S2/c1-3-4-10(8-24)20-14-13-15(23-17(25)27-13)22-16(21-14)26-9(2)11-7-19-6-5-12(11)18/h5-7,9-10,24H,3-4,8H2,1-2H3,(H2,20,21,22,23,25)/t9-,10+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50432447 (CHEMBL2349334) Show SMILES CC[C@H](CO)Nc1nc(SCc2ccccc2)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C16H18N4O2S2/c1-2-11(8-21)17-13-12-14(20-16(22)24-12)19-15(18-13)23-9-10-6-4-3-5-7-10/h3-7,11,21H,2,8-9H2,1H3,(H2,17,18,19,20,22)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432437 (CHEMBL2349324) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2F)nc2nc(N)sc12 |r| Show InChI InChI=1S/C18H22FN5OS2/c1-10(2)7-12(8-25)21-15-14-16(22-17(20)27-14)24-18(23-15)26-9-11-5-3-4-6-13(11)19/h3-6,10,12,25H,7-9H2,1-2H3,(H3,20,21,22,23,24)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432468 (CHEMBL2349319) Show SMILES CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2cccc(c2)S(C)(=O)=O)nc2nc(N)sc12 |r| Show InChI InChI=1S/C20H27N5O3S3/c1-11(2)8-14(10-26)22-17-16-18(23-19(21)30-16)25-20(24-17)29-12(3)13-6-5-7-15(9-13)31(4,27)28/h5-7,9,11-12,14,26H,8,10H2,1-4H3,(H3,21,22,23,24,25)/t12-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432440 (CHEMBL2349321) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C18H22N4O2S2/c1-11(2)8-13(9-23)19-15-14-16(22-18(24)26-14)21-17(20-15)25-10-12-6-4-3-5-7-12/h3-7,11,13,23H,8-10H2,1-2H3,(H2,19,20,21,22,24)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432433 (CHEMBL2349328) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2cccc(Br)c2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C18H22BrN5OS2/c1-10(2)6-13(8-25)21-15-14-16(22-17(20)27-14)24-18(23-15)26-9-11-4-3-5-12(19)7-11/h3-5,7,10,13,25H,6,8-9H2,1-2H3,(H3,20,21,22,23,24)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432470 (CHEMBL2349317) Show SMILES CCC[C@H](CO)Nc1nc(S[C@@H](C)c2cccc(c2)C#N)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H22N6OS2/c1-3-5-14(10-26)22-16-15-17(23-18(21)28-15)25-19(24-16)27-11(2)13-7-4-6-12(8-13)9-20/h4,6-8,11,14,26H,3,5,10H2,1-2H3,(H3,21,22,23,24,25)/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432456 (CHEMBL2349302) Show SMILES COC(=O)[C@@H](CC(C)C)Nc1nc(SCc2ccccc2Cl)nc2nc(N)sc12 |r| Show InChI InChI=1S/C19H22ClN5O2S2/c1-10(2)8-13(17(26)27-3)22-15-14-16(23-18(21)29-14)25-19(24-15)28-9-11-6-4-5-7-12(11)20/h4-7,10,13H,8-9H2,1-3H3,(H3,21,22,23,24,25)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432459 (CHEMBL2349186) Show SMILES CC(C)C[C@H](CO)Nc1nc(OCc2ccccc2)[nH]c2nc(=O)sc12 |r| Show InChI InChI=1S/C18H22N4O3S/c1-11(2)8-13(9-23)19-15-14-16(22-18(24)26-14)21-17(20-15)25-10-12-6-4-3-5-7-12/h3-7,11,13,23H,8-10H2,1-2H3,(H2,19,20,21,22,24)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical R & D, Astra Arcus AB Curated by PDSP Ki Database									J Pharmacol Exp Ther 283: 216-25 (1997) BindingDB Entry DOI: 10.7270/Q22Z142T
					More data for this Ligand-Target Pair
CX3C chemokine receptor 1 (Homo sapiens (Human))	BDBM50432431 (CHEMBL2349330) Show SMILES CC(C)C[C@H](CO)Nc1nc(SCc2ccc(Br)cc2)nc2nc(N)sc12 |r| Show InChI InChI=1S/C18H22BrN5OS2/c1-10(2)7-13(8-25)21-15-14-16(22-17(20)27-14)24-18(23-15)26-9-11-3-5-12(19)6-4-11/h3-6,10,13,25H,7-9H2,1-2H3,(H3,20,21,22,23,24)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis				J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 595 total )  |  Next  |  Last  >>

Jump to: