Found 720 hits with Last Name = 'southall' and Initial = 'nt' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50459091
(ABL-001 | ABL001 | ABL001-NX | Asciminib | NVP-ABL...)Show SMILES O[C@@H]1CCN(C1)c1ncc(cc1-c1cc[nH]n1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1 |r| Show InChI InChI=1S/C20H18ClF2N5O3/c21-20(22,23)31-15-3-1-13(2-4-15)26-19(30)12-9-16(17-5-7-25-27-17)18(24-10-12)28-8-6-14(29)11-28/h1-5,7,9-10,14,29H,6,8,11H2,(H,25,27)(H,26,30)/t14-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50237710
(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Luciferin 4-monooxygenase
(Photuris pennsylvanica) | BDBM50238226
(2-(5-biphenyl-4-yl-[1,2,4]oxadiazol-3-yl)-pyridine...)Show InChI InChI=1S/C19H13N3O/c1-2-6-14(7-3-1)15-9-11-16(12-10-15)19-21-18(22-23-19)17-8-4-5-13-20-17/h1-13H | UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photuris pennsylvanica) | BDBM50293100
(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl biphenyl-4-c...)Show SMILES O=C(Oc1nc(no1)-c1ccccn1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H13N3O3/c24-19(16-11-9-15(10-12-16)14-6-2-1-3-7-14)25-20-22-18(23-26-20)17-8-4-5-13-21-17/h1-13H | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602606
(US11649218, Example NCGC00508975)Show SMILES O[C@H]1CCN(C1)c1cc(ccn1)-c1ccc2Oc3ccc(OC(F)(F)F)cc3NC(=O)c2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478348
(CHEMBL406835)Show InChI InChI=1S/C19H12O3/c20-15-8-4-3-7-14(15)18-11-16(21)19-13-6-2-1-5-12(13)9-10-17(19)22-18/h1-11,20H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photuris pennsylvanica) | BDBM50293101
(5-(2,4-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole ...)Show InChI InChI=1S/C16H14N2O3/c1-19-12-8-9-13(14(10-12)20-2)16-17-15(18-21-16)11-6-4-3-5-7-11/h3-10H,1-2H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478348
(CHEMBL406835)Show InChI InChI=1S/C19H12O3/c20-15-8-4-3-7-14(15)18-11-16(21)19-13-6-2-1-5-12(13)9-10-17(19)22-18/h1-11,20H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478343
(CHEMBL258888 | CID 2260658)Show InChI InChI=1S/C14H11BrN2O/c15-11-5-1-2-6-12(11)17-10-8-14(18)13-7-3-4-9-16-13/h1-10,17H/b10-8- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238208
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238226
(2-(5-biphenyl-4-yl-[1,2,4]oxadiazol-3-yl)-pyridine...)Show InChI InChI=1S/C19H13N3O/c1-2-6-14(7-3-1)15-9-11-16(12-10-15)19-21-18(22-23-19)17-8-4-5-13-20-17/h1-13H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photinus pyralis luciferase by noncompetitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photuris pennsylvanica) | BDBM50293102
(5-(2-methoxyphenyl)-3-(pyridin-2-yl)-1,2,4-oxadiaz...)Show InChI InChI=1S/C14H11N3O2/c1-18-12-8-3-2-6-10(12)14-16-13(17-19-14)11-7-4-5-9-15-11/h2-9H,1H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478343
(CHEMBL258888 | CID 2260658)Show InChI InChI=1S/C14H11BrN2O/c15-11-5-1-2-6-12(11)17-10-8-14(18)13-7-3-4-9-16-13/h1-10,17H/b10-8- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602609
(US11649218, Example NCGC00507975)Show SMILES O[C@@H]1CCN(C1)c1cc(ccn1)-c1ccc2Oc3ccc(OC(F)(F)F)cc3NC(=O)c2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478348
(CHEMBL406835)Show InChI InChI=1S/C19H12O3/c20-15-8-4-3-7-14(15)18-11-16(21)19-13-6-2-1-5-12(13)9-10-17(19)22-18/h1-11,20H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39025
(2-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine | ...)Show InChI InChI=1S/C17H11N3O/c1-2-6-13-11-14(9-8-12(13)5-1)17-19-16(20-21-17)15-7-3-4-10-18-15/h1-11H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238226
(2-(5-biphenyl-4-yl-[1,2,4]oxadiazol-3-yl)-pyridine...)Show InChI InChI=1S/C19H13N3O/c1-2-6-14(7-3-1)15-9-11-16(12-10-15)19-21-18(22-23-19)17-8-4-5-13-20-17/h1-13H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602536
(US11649218, Example NCGC00483140)Show SMILES FC(F)(F)Oc1ccc2c(NC(=O)c3cc(ccc3S2(=O)=O)-c2ccnc(c2)N2CCOCC2)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602608
(US11649218, Example NCGC00508838)Show SMILES CN(CCO)c1cc(ccn1)-c1ccc2Oc3ccc(OC(F)(F)F)cc3NC(=O)c2c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602612
(US11649218, Example NCGC00508972)Show SMILES CN(CCO)c1cccc(n1)-c1ccc2Oc3ccc(OC(F)(F)F)cc3NC(=O)c2c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602537
(US11649218, Example NCGC00481508)Show SMILES OCc1ccc2Nc3ccc(cc3C(=O)Nc2c1)-c1ccnc(c1)N1CCOCC1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602611
(US11649218, Example NCGC00532289)Show SMILES O[C@@H]1CCN(C1)c1cccc(n1)-c1ccc2Oc3ccc(OC(F)(F)F)cc3NC(=O)c2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM37601
(3-(1H-benzimidazol-2-yl)-7-(diethylamino)-1-benzop...)Show SMILES CCN(CC)c1ccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc2c1 Show InChI InChI=1S/C20H19N3O2/c1-3-23(4-2)14-10-9-13-11-15(20(24)25-18(13)12-14)19-21-16-7-5-6-8-17(16)22-19/h5-12H,3-4H2,1-2H3,(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238226
(2-(5-biphenyl-4-yl-[1,2,4]oxadiazol-3-yl)-pyridine...)Show InChI InChI=1S/C19H13N3O/c1-2-6-14(7-3-1)15-9-11-16(12-10-15)19-21-18(22-23-19)17-8-4-5-13-20-17/h1-13H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39048
(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)Show InChI InChI=1S/C15H11ClN2O/c1-10-7-8-12(13(16)9-10)15-17-14(18-19-15)11-5-3-2-4-6-11/h2-9H,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50293101
(5-(2,4-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole ...)Show InChI InChI=1S/C16H14N2O3/c1-19-12-8-9-13(14(10-12)20-2)16-17-15(18-21-16)11-6-4-3-5-7-11/h3-10H,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM38943
(2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...)Show InChI InChI=1S/C15H9N3OS/c19-14-11-6-2-1-5-10(11)9-16-18(14)15-17-12-7-3-4-8-13(12)20-15/h1-9H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Easy lite assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39048
(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)Show InChI InChI=1S/C15H11ClN2O/c1-10-7-8-12(13(16)9-10)15-17-14(18-19-15)11-5-3-2-4-6-11/h2-9H,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602538
(US11649218, Example NCGC00411866)Show SMILES OCc1ccc2Oc3ccc(cc3C(=O)Nc2c1)-c1ccnc(c1)N1CCOCC1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 166 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478343
(CHEMBL258888 | CID 2260658)Show InChI InChI=1S/C14H11BrN2O/c15-11-5-1-2-6-12(11)17-10-8-14(18)13-7-3-4-9-16-13/h1-10,17H/b10-8- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Easy lite assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478343
(CHEMBL258888 | CID 2260658)Show InChI InChI=1S/C14H11BrN2O/c15-11-5-1-2-6-12(11)17-10-8-14(18)13-7-3-4-9-16-13/h1-10,17H/b10-8- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by PK-Light assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602539
(US11649218, Example NCGC00355551)Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1ccc2Nc3ccc(OC(F)(F)F)cc3NC(=O)c2c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 187 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238208
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50129791
((4-Benzothiazol-2-yl-phenyl)-dimethyl-amine | 4-(B...)Show InChI InChI=1S/C15H14N2S/c1-17(2)12-9-7-11(8-10-12)15-16-13-5-3-4-6-14(13)18-15/h3-10H,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photinus pyralis luciferase by competitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478349
((R)-INDOPROFEN | indoprofen)Show InChI InChI=1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)/t11-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478343
(CHEMBL258888 | CID 2260658)Show InChI InChI=1S/C14H11BrN2O/c15-11-5-1-2-6-12(11)17-10-8-14(18)13-7-3-4-9-16-13/h1-10,17H/b10-8- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50293101
(5-(2,4-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole ...)Show InChI InChI=1S/C16H14N2O3/c1-19-12-8-9-13(14(10-12)20-2)16-17-15(18-21-16)11-6-4-3-5-7-11/h3-10H,1-2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description Inhibition of luciferin binding site of Photinus pyralis luciferase by noncompetitive inhibition assay |
J Med Chem 52: 1450-8 (2010)
Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478348
(CHEMBL406835)Show InChI InChI=1S/C19H12O3/c20-15-8-4-3-7-14(15)18-11-16(21)19-13-6-2-1-5-12(13)9-10-17(19)22-18/h1-11,20H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Easy lite assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM38943
(2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...)Show InChI InChI=1S/C15H9N3OS/c19-14-11-6-2-1-5-10(11)9-16-18(14)15-17-12-7-3-4-8-13(12)20-15/h1-9H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by PK-Light assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39025
(2-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine | ...)Show InChI InChI=1S/C17H11N3O/c1-2-6-13-11-14(9-8-12(13)5-1)17-19-16(20-21-17)15-7-3-4-10-18-15/h1-11H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39025
(2-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine | ...)Show InChI InChI=1S/C17H11N3O/c1-2-6-13-11-14(9-8-12(13)5-1)17-19-16(20-21-17)15-7-3-4-10-18-15/h1-11H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50478352
(CHEMBL264933 | CID 2188632)Show InChI InChI=1S/C17H18N2O/c1-19(2)16-10-8-15(9-11-16)18-13-12-17(20)14-6-4-3-5-7-14/h3-13,18H,1-2H3/b13-12- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39025
(2-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine | ...)Show InChI InChI=1S/C17H11N3O/c1-2-6-13-11-14(9-8-12(13)5-1)17-19-16(20-21-17)15-7-3-4-10-18-15/h1-11H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by PK-Light assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM38894
(5-(3-chloranyl-4-methyl-phenyl)-3-pyridin-2-yl-1,2...)Show InChI InChI=1S/C14H10ClN3O/c1-9-5-6-10(8-11(9)15)14-17-13(18-19-14)12-4-2-3-7-16-12/h2-8H,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM39025
(2-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine | ...)Show InChI InChI=1S/C17H11N3O/c1-2-6-13-11-14(9-8-12(13)5-1)17-19-16(20-21-17)15-7-3-4-10-18-15/h1-11H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Easy lite assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602540
(US11649218, Example NCGC00481504)Show SMILES FC(F)(F)COc1ccc2Oc3ccc(cc3C(=O)Nc2c1)-c1ccnc(c1)N1CCOCC1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM37601
(3-(1H-benzimidazol-2-yl)-7-(diethylamino)-1-benzop...)Show SMILES CCN(CC)c1ccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc2c1 Show InChI InChI=1S/C20H19N3O2/c1-3-23(4-2)14-10-9-13-11-15(20(24)25-18(13)12-14)19-21-16-7-5-6-8-17(16)22-19/h5-12H,3-4H2,1-2H3,(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238208
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by PK-Light assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM602541
(US11649218, Example NCGC00482446)Show SMILES FC(F)(F)Oc1ccc2c(NC(=O)c3cc(ccc3S2=O)-c2ccnc(c2)N2CCOCC2)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 264 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RX9H0C |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Photinus pyralis) | BDBM50238208
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Photinus pyralis luciferase by Easy lite assay |
J Med Chem 51: 2372-86 (2008)
Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ |
More data for this Ligand-Target Pair | |