Found 39 hits with Last Name = 'sridhar' and Initial = 'r' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]
(Human immunodeficiency virus type 1) | BDBM13925
((3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl ...)Show SMILES [H][C@]1(C[C@]2([H])CCO[C@]2([H])C1)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(CO)cc1 |r| Show InChI InChI=1S/C29H40N2O7S/c1-20(2)17-31(39(35,36)25-10-8-22(19-32)9-11-25)18-27(33)26(14-21-6-4-3-5-7-21)30-29(34)38-24-15-23-12-13-37-28(23)16-24/h3-11,20,23-24,26-28,32-33H,12-19H2,1-2H3,(H,30,34)/t23-,24+,26-,27+,28+/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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| MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.00450 | -64.8 | n/a | n/a | n/a | n/a | n/a | 6.4 | 25 |
Purdue University
| Assay Description The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar... |
J Med Chem 49: 5252-61 (2006)
Article DOI: 10.1021/jm060561m BindingDB Entry DOI: 10.7270/Q23R0R41 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]
(Human immunodeficiency virus type 1) | BDBM8125
((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)Show SMILES [H][C@@]1(CO[C@@]2([H])OCC[C@@]12[H])OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(N)cc1 |r| Show InChI InChI=1S/C27H37N3O7S/c1-18(2)15-30(38(33,34)21-10-8-20(28)9-11-21)16-24(31)23(14-19-6-4-3-5-7-19)29-27(32)37-25-17-36-26-22(25)12-13-35-26/h3-11,18,22-26,31H,12-17,28H2,1-2H3,(H,29,32)/t22-,23-,24+,25-,26+/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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| PDB Article PubMed
| 0.0140 | -62.0 | n/a | n/a | n/a | n/a | n/a | 6.4 | 25 |
Purdue University
| Assay Description The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar... |
J Med Chem 49: 5252-61 (2006)
Article DOI: 10.1021/jm060561m BindingDB Entry DOI: 10.7270/Q23R0R41 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]
(Human immunodeficiency virus type 1) | BDBM13924
((3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl ...)Show SMILES [H][C@]1(C[C@]2([H])CCO[C@]2([H])C1)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(N)cc1 |r| Show InChI InChI=1S/C28H39N3O6S/c1-19(2)17-31(38(34,35)24-10-8-22(29)9-11-24)18-26(32)25(14-20-6-4-3-5-7-20)30-28(33)37-23-15-21-12-13-36-27(21)16-23/h3-11,19,21,23,25-27,32H,12-18,29H2,1-2H3,(H,30,33)/t21-,23+,25-,26+,27+/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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| PC cid PC sid UniChem
Patents
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| Article PubMed
| 0.140 | -56.2 | n/a | n/a | n/a | n/a | n/a | 6.4 | 25 |
Purdue University
| Assay Description The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar... |
J Med Chem 49: 5252-61 (2006)
Article DOI: 10.1021/jm060561m BindingDB Entry DOI: 10.7270/Q23R0R41 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(RAT) | BDBM50241083
(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at rat MCHR1 |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(RAT) | BDBM50094880
(CHEMBL3589145)Show SMILES CN[C@H]1CCN(C1)c1ccc(cn1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H21ClN6O/c1-23-16-8-9-26(13-16)19-7-6-18(10-24-19)27-11-14-12-28(25-20(14)21(27)29)17-4-2-15(22)3-5-17/h2-7,10,12,16,23H,8-9,11,13H2,1H3/t16-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at rat MCHR1 |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(RAT) | BDBM50094885
(CHEMBL3588863)Show SMILES COc1cc(ccc1OCC(C)(C)OC(=O)CN)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H25ClN4O5/c1-24(2,34-21(30)11-26)14-33-19-9-8-18(10-20(19)32-3)28-12-15-13-29(27-22(15)23(28)31)17-6-4-16(25)5-7-17/h4-10,13H,11-12,14,26H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at rat MCHR1 assessed as 2-(4-chlorophenyl)-5-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(... |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]
(Human immunodeficiency virus type 1) | BDBM13926
((2R,3aR,6aS)-octahydropentalen-2-yl N-[(2S,3R)-3-h...)Show SMILES [H][C@]1(C[C@]2([H])CCC[C@]2([H])C1)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(CO)cc1 |r| Show InChI InChI=1S/C30H42N2O6S/c1-21(2)18-32(39(36,37)27-13-11-23(20-33)12-14-27)19-29(34)28(15-22-7-4-3-5-8-22)31-30(35)38-26-16-24-9-6-10-25(24)17-26/h3-5,7-8,11-14,21,24-26,28-29,33-34H,6,9-10,15-20H2,1-2H3,(H,31,35)/t24-,25+,26+,28-,29+/m0/s1 | PDB MMDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| 5.30 | -47.2 | n/a | n/a | n/a | n/a | n/a | 6.4 | 25 |
Purdue University
| Assay Description The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar... |
J Med Chem 49: 5252-61 (2006)
Article DOI: 10.1021/jm060561m BindingDB Entry DOI: 10.7270/Q23R0R41 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(RAT) | BDBM50094881
(CHEMBL3589155)Show SMILES COc1cc(ccc1OCC(C)(C)OC(=O)CN)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN3O5S/c1-25(2,34-22(30)12-27)13-33-19-9-8-17(10-20(19)32-3)29-14-28-18-11-21(35-23(18)24(29)31)15-4-6-16(26)7-5-15/h4-11,14H,12-13,27H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at rat MCHR1 assessed as 6-(4-chlorophenyl)-3-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-one |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50094884
(CHEMBL3589154)Show SMILES COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN2O4S/c1-23(2,28)12-30-18-9-8-16(10-19(18)29-3)26-13-25-17-11-20(31-21(17)22(26)27)14-4-6-15(24)7-5-14/h4-11,13,28H,12H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ... |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50241083
(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ... |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50094880
(CHEMBL3589145)Show SMILES CN[C@H]1CCN(C1)c1ccc(cn1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H21ClN6O/c1-23-16-8-9-26(13-16)19-7-6-18(10-24-19)27-11-14-12-28(25-20(14)21(27)29)17-4-2-15(22)3-5-17/h2-7,10,12,16,23H,8-9,11,13H2,1H3/t16-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 241 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ... |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50094882
(CHEMBL3589135)Show SMILES COc1cc(ccc1OCC(C)(C)O)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H22ClN3O4/c1-22(2,28)13-30-18-9-8-17(10-19(18)29-3)25-11-14-12-26(24-20(14)21(25)27)16-6-4-15(23)5-7-16/h4-10,12,28H,11,13H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ... |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM22372
(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)Show SMILES C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50006811
(2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-p...)Show SMILES Cc1c(C)c(O)c(C=CCCC#CCCCC#CCO)c(C)c1O |w:8.8| Show InChI InChI=1S/C21H26O3/c1-16-17(2)21(24)19(18(3)20(16)23)14-12-10-8-6-4-5-7-9-11-13-15-22/h12,14,22-24H,5,7-10,15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50094883
(CHEMBL3589138)Show SMILES COc1cc(ccc1OCCN1CCCC1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H25ClN4O3/c1-31-22-14-20(8-9-21(22)32-13-12-27-10-2-3-11-27)28-15-17-16-29(26-23(17)24(28)30)19-6-4-18(25)5-7-19/h4-9,14,16H,2-3,10-13,15H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ... |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324109
(3,4,5-Trimethoxy-2',4'-di-O-prenylchalcone | CHEMB...)Show SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8]-[#6]\[#6]=[#6](/[#6])-[#6])cc(-[#8]-[#6])c1-[#8]-[#6] Show InChI InChI=1S/C28H34O6/c1-19(2)12-14-33-22-9-10-23(25(18-22)34-15-13-20(3)4)24(29)11-8-21-16-26(30-5)28(32-7)27(17-21)31-6/h8-13,16-18H,14-15H2,1-7H3/b11-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359871
(CHEMBL1929096)Show InChI InChI=1S/C21H24O2S/c1-16(2)18-8-10-19(11-9-18)21(22)5-4-14-23-15-17-6-12-20(24-3)13-7-17/h6-13,16,21-22H,14-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324108
(3,4-Dimethoxy-2',4'-di-O-prenylchalcone | CHEMBL12...)Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc1-[#8]-[#6] Show InChI InChI=1S/C27H32O5/c1-19(2)13-15-31-22-9-10-23(26(18-22)32-16-14-20(3)4)24(28)11-7-21-8-12-25(29-5)27(17-21)30-6/h7-14,17-18H,15-16H2,1-6H3/b11-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359870
(CHEMBL1929095)Show InChI InChI=1S/C18H17FO2S/c1-22-17-10-4-14(5-11-17)13-21-12-2-3-18(20)15-6-8-16(19)9-7-15/h4-11,18,20H,12-13H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324106
(2,3-Dimethoxy-2',4'-di-O-prenylchalcone | CHEMBL12...)Show SMILES [#6]-[#8]-c1cccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c1-[#8]-[#6] Show InChI InChI=1S/C27H32O5/c1-19(2)14-16-31-22-11-12-23(26(18-22)32-17-15-20(3)4)24(28)13-10-21-8-7-9-25(29-5)27(21)30-6/h7-15,18H,16-17H2,1-6H3/b13-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50094879
(CHEMBL3589153)Show SMILES COc1cc(ccc1N1C[C@H](O)[C@@H](O)C1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H21ClN4O4/c1-31-20-8-16(6-7-17(20)25-11-18(28)19(29)12-25)26-9-13-10-27(24-21(13)22(26)30)15-4-2-14(23)3-5-15/h2-8,10,18-19,28-29H,9,11-12H2,1H3/t18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human ERG expressed in CHO cells by automated whole-cell patch clamp electrophysiology system |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359868
(CHEMBL1929093)Show InChI InChI=1S/C19H17NO2S/c1-23-18-10-6-16(7-11-18)14-22-12-2-3-19(21)17-8-4-15(13-20)5-9-17/h4-11,19,21H,12,14H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324107
(2,3,4-Trimethoxy-2',4'-di-O-prenylchalcone | CHEMB...)Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8]-[#6]\[#6]=[#6](/[#6])-[#6])c(-[#8]-[#6])c1-[#8]-[#6] Show InChI InChI=1S/C28H34O6/c1-19(2)14-16-33-22-10-11-23(26(18-22)34-17-15-20(3)4)24(29)12-8-21-9-13-25(30-5)28(32-7)27(21)31-6/h8-15,18H,16-17H2,1-7H3/b12-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359869
(CHEMBL1929094)Show SMILES CSc1ccc(COCC#CC(O)c2cccc(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C18H17NO4S/c1-24-17-9-7-14(8-10-17)13-23-11-3-6-18(20)15-4-2-5-16(12-15)19(21)22/h2,4-5,7-10,12,18,20H,11,13H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359864
(CHEMBL1929089)Show InChI InChI=1S/C20H22O4S/c1-22-19-8-4-6-17(20(19)23-2)18(21)7-5-13-24-14-15-9-11-16(25-3)12-10-15/h4,6,8-12,18,21H,13-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359865
(CHEMBL1929090)Show InChI InChI=1S/C21H24O5S/c1-23-19-12-11-17(20(24-2)21(19)25-3)18(22)6-5-13-26-14-15-7-9-16(27-4)10-8-15/h7-12,18,22H,13-14H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50094878
(CHEMBL3589152)Show SMILES COc1cc(ccc1N1CC[C@@H](O)C1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H21ClN4O3/c1-30-20-10-17(6-7-19(20)25-9-8-18(28)13-25)26-11-14-12-27(24-21(14)22(26)29)16-4-2-15(23)3-5-16/h2-7,10,12,18,28H,8-9,11,13H2,1H3/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human ERG expressed in CHO cells by automated whole-cell patch clamp electrophysiology system |
Bioorg Med Chem Lett 25: 2793-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359867
(CHEMBL1929092)Show InChI InChI=1S/C21H24O5S/c1-23-19-12-16(13-20(24-2)21(19)25-3)18(22)6-5-11-26-14-15-7-9-17(27-4)10-8-15/h7-10,12-13,18,22H,11,14H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359866
(CHEMBL1929091)Show InChI InChI=1S/C20H22O4S/c1-22-19-11-8-16(13-20(19)23-2)18(21)5-4-12-24-14-15-6-9-17(25-3)10-7-15/h6-11,13,18,21H,12,14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359863
(CHEMBL1929088)Show InChI InChI=1S/C19H20O3S/c1-21-17-9-7-16(8-10-17)19(20)4-3-13-22-14-15-5-11-18(23-2)12-6-15/h5-12,19-20H,13-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359862
(CHEMBL1929087)Show InChI InChI=1S/C17H24O2S/c1-3-4-5-7-16(18)8-6-13-19-14-15-9-11-17(20-2)12-10-15/h9-12,16,18H,3-5,7,13-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359861
(CHEMBL1929086)Show InChI InChI=1S/C17H16O2/c18-17(16-10-5-2-6-11-16)12-7-13-19-14-15-8-3-1-4-9-15/h1-6,8-11,17-18H,13-14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec... |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM29149
(substituted chalcone, 5c)Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8])cc1 Show InChI InChI=1S/C21H22O4/c1-15(2)12-13-25-18-9-10-19(21(23)14-18)20(22)11-6-16-4-7-17(24-3)8-5-16/h4-12,14,23H,13H2,1-3H3/b11-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324105
(4-Methoxy-2',4'-di-O-prenylchalcone | CHEMBL121504...)Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](/[#6])-[#6])cc2-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc1 Show InChI InChI=1S/C26H30O4/c1-19(2)14-16-29-23-11-12-24(26(18-23)30-17-15-20(3)4)25(27)13-8-21-6-9-22(28-5)10-7-21/h6-15,18H,16-17H2,1-5H3/b13-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324104
(2'-Hydroxy-3,4,5-trimethoxy-4'-O-prenylchalcone | ...)Show SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8])cc(-[#8]-[#6])c1-[#8]-[#6] Show InChI InChI=1S/C23H26O6/c1-15(2)10-11-29-17-7-8-18(20(25)14-17)19(24)9-6-16-12-21(26-3)23(28-5)22(13-16)27-4/h6-10,12-14,25H,11H2,1-5H3/b9-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324101
(2'-Hydroxy-2,3-dimethoxy-4'-O-prenylchalcone | CHE...)Show SMILES [#6]-[#8]-c1cccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](/[#6])-[#6])cc2-[#8])c1-[#8]-[#6] Show InChI InChI=1S/C22H24O5/c1-15(2)12-13-27-17-9-10-18(20(24)14-17)19(23)11-8-16-6-5-7-21(25-3)22(16)26-4/h5-12,14,24H,13H2,1-4H3/b11-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324102
(2'-Hydroxy-2,3,4-trimethoxy-4'-O-prenylchalcone | ...)Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])cc2-[#8])c(-[#8]-[#6])c1-[#8]-[#6] Show InChI InChI=1S/C23H26O6/c1-15(2)12-13-29-17-8-9-18(20(25)14-17)19(24)10-6-16-7-11-21(26-3)23(28-5)22(16)27-4/h6-12,14,25H,13H2,1-5H3/b10-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50324103
(2'-Hydroxy-3,4-dimethoxy-4'-O-prenylchalcone | CHE...)Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](=O)-c2ccc(-[#8]-[#6]\[#6]=[#6](/[#6])-[#6])cc2-[#8])cc1-[#8]-[#6] Show InChI InChI=1S/C22H24O5/c1-15(2)11-12-27-17-7-8-18(20(24)14-17)19(23)9-5-16-6-10-21(25-3)22(13-16)26-4/h5-11,13-14,24H,12H2,1-4H3/b9-5+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-lipoxygenase |
Bioorg Med Chem 18: 5807-15 (2010)
Article DOI: 10.1016/j.bmc.2010.06.107 BindingDB Entry DOI: 10.7270/Q2KH0NHN |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50359860
(CHEMBL1929097)Show InChI InChI=1S/C14H18O2/c1-2-7-14(15)10-6-11-16-12-13-8-4-3-5-9-13/h3-5,8-9,14-15H,2,7,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX |
Eur J Med Chem 47: 351-9 (2012)
Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW |
More data for this Ligand-Target Pair | |