Compile Data Set for Download or QSAR

Found 5277 hits with Last Name = 'stafford' and Initial = 'ja'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Translocator protein (Rattus norvegicus (rat))	BDBM21363 (12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triaza...) Show SMILES Cc1ncc2CN=C(c3ccccc3F)c3cc(Cl)ccc3-n12 |t:6| Show InChI InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120340 (3-[(S)-7-Chloro-5-(2-fluoro-phenyl)-2-oxo-2,3-dihy...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2NC1=O |t:7| Show InChI InChI=1S/C19H16ClFN2O3/c1-26-17(24)9-8-16-19(25)23-15-7-6-11(20)10-13(15)18(22-16)12-4-2-3-5-14(12)21/h2-7,10,16H,8-9H2,1H3,(H,23,25)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120353 (3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-4H-3,5,10b-tri...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2-n2ccnc12 |t:7| Show InChI InChI=1S/C21H17ClFN3O2/c1-28-19(27)9-7-17-21-24-10-11-26(21)18-8-6-13(22)12-15(18)20(25-17)14-4-2-3-5-16(14)23/h2-6,8,10-12,17H,7,9H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120343 (3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-2-methyl-4H-3,...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2-n2cc(C)nc12 |t:7| Show InChI InChI=1S/C22H19ClFN3O2/c1-13-12-27-19-9-7-14(23)11-16(19)21(15-5-3-4-6-17(15)24)26-18(22(27)25-13)8-10-20(28)29-2/h3-7,9,11-12,18H,8,10H2,1-2H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120360 (3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-1-methyl-4H-3,...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2-n2c(C)cnc12 |t:7| Show InChI InChI=1S/C22H19ClFN3O2/c1-13-12-25-22-18(8-10-20(28)29-2)26-21(15-5-3-4-6-17(15)24)16-11-14(23)7-9-19(16)27(13)22/h3-7,9,11-12,18H,8,10H2,1-2H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120344 (3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-1-methyl-4H-2,...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2-n2c(C)ncc12 |t:7| Show InChI InChI=1S/C22H19ClFN3O2/c1-13-25-12-20-18(8-10-21(28)29-2)26-22(15-5-3-4-6-17(15)24)16-11-14(23)7-9-19(16)27(13)20/h3-7,9,11-12,18H,8,10H2,1-2H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029954 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@H]1CCN2[C@@H]1CNC2=O Show InChI InChI=1S/C18H24N2O3/c1-22-16-7-6-12(10-17(16)23-13-4-2-3-5-13)14-8-9-20-15(14)11-19-18(20)21/h6-7,10,13-15H,2-5,8-9,11H2,1H3,(H,19,21)/t14-,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50048248 ((3S,4R)-3-Acetyl-4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COC(=O)N1C[C@H]([C@@H](C1)c1ccc(OC)c(OC2CCCC2)c1)C(C)=O Show InChI InChI=1S/C20H27NO5/c1-13(22)16-11-21(20(23)25-3)12-17(16)14-8-9-18(24-2)19(10-14)26-15-6-4-5-7-15/h8-10,15-17H,4-7,11-12H2,1-3H3/t16-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470745 (CHEMBL286840) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)OC(C)(C)C Show InChI InChI=1S/C21H31NO4/c1-21(2,3)26-20(23)22-12-11-16(14-22)15-9-10-18(24-4)19(13-15)25-17-7-5-6-8-17/h9-10,13,16-17H,5-8,11-12,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285059 (1-(tert-butyl) 3-methyl 4-(3-cyclopentyloxy-4-meth...) Show SMILES COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C(=O)OC(C)(C)C Show InChI InChI=1S/C23H33NO6/c1-23(2,3)30-22(26)24-13-17(18(14-24)21(25)28-5)15-10-11-19(27-4)20(12-15)29-16-8-6-7-9-16/h10-12,16-18H,6-9,13-14H2,1-5H3/t17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470752 (CHEMBL38328) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)Oc1ccccc1 Show InChI InChI=1S/C23H27NO4/c1-26-21-12-11-17(15-22(21)27-19-9-5-6-10-19)18-13-14-24(16-18)23(25)28-20-7-3-2-4-8-20/h2-4,7-8,11-12,15,18-19H,5-6,9-10,13-14,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285045 (1-isopropyl 3-methyl 4-(3-cyclopentyloxy-4-methoxy...) Show SMILES COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C(=O)OC(C)C Show InChI InChI=1S/C22H31NO6/c1-14(2)28-22(25)23-12-17(18(13-23)21(24)27-4)15-9-10-19(26-3)20(11-15)29-16-7-5-6-8-16/h9-11,14,16-18H,5-8,12-13H2,1-4H3/t17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470756 (CHEMBL37453) Show SMILES CCCOC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C20H29NO4/c1-3-12-24-20(22)21-11-10-16(14-21)15-8-9-18(23-2)19(13-15)25-17-6-4-5-7-17/h8-9,13,16-17H,3-7,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285042 (CHEMBL302632 | tert-butyl 3-(3-cyclopentyloxy-4-me...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1CO)C(=O)OC(C)(C)C Show InChI InChI=1S/C22H33NO5/c1-22(2,3)28-21(25)23-12-16(14-24)18(13-23)15-9-10-19(26-4)20(11-15)27-17-7-5-6-8-17/h9-11,16-18,24H,5-8,12-14H2,1-4H3/t16-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285038 (1-benzyl 3-methyl 4-(3-cyclopentyloxy-4-methoxyphe...) Show SMILES COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C26H31NO6/c1-30-23-13-12-19(14-24(23)33-20-10-6-7-11-20)21-15-27(16-22(21)25(28)31-2)26(29)32-17-18-8-4-3-5-9-18/h3-5,8-9,12-14,20-22H,6-7,10-11,15-17H2,1-2H3/t21-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470750 (CHEMBL286291) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)c1cccn1C Show InChI InChI=1S/C22H28N2O3/c1-23-12-5-8-19(23)22(25)24-13-11-17(15-24)16-9-10-20(26-2)21(14-16)27-18-6-3-4-7-18/h5,8-10,12,14,17-18H,3-4,6-7,11,13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470731 (CHEMBL146946) Show SMILES COC(=O)N1CC[C@@H](C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C18H25NO4/c1-21-16-8-7-13(11-17(16)23-15-5-3-4-6-15)14-9-10-19(12-14)18(20)22-2/h7-8,11,14-15H,3-6,9-10,12H2,1-2H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470736 (CHEMBL37029) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C24H29NO4/c1-27-22-12-11-19(15-23(22)29-21-9-5-6-10-21)20-13-14-25(16-20)24(26)28-17-18-7-3-2-4-8-18/h2-4,7-8,11-12,15,20-21H,5-6,9-10,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285050 (CHEMBL59386 | methyl 3-(3-cyclopentyloxy-4-methoxy...) Show SMILES COC(=O)N1C[C@H]([C@@H](C1)[N+]([O-])=O)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C18H24N2O6/c1-24-16-8-7-12(9-17(16)26-13-5-3-4-6-13)14-10-19(18(21)25-2)11-15(14)20(22)23/h7-9,13-15H,3-6,10-11H2,1-2H3/t14-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120359 (3-((S)-8-Chloro-2-methyl-6-pyridin-2-yl-4H-3,5,10b...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2-n2cc(C)nc12 |t:7| Show InChI InChI=1S/C21H19ClN4O2/c1-13-12-26-18-8-6-14(22)11-15(18)20(16-5-3-4-10-23-16)25-17(21(26)24-13)7-9-19(27)28-2/h3-6,8,10-12,17H,7,9H2,1-2H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029955 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@H]1CCN2[C@@H]1CCC2=O Show InChI InChI=1S/C19H25NO3/c1-22-17-8-6-13(12-18(17)23-14-4-2-3-5-14)15-10-11-20-16(15)7-9-19(20)21/h6,8,12,14-16H,2-5,7,9-11H2,1H3/t15-,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470740 (CHEMBL264851) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)OC(C)C Show InChI InChI=1S/C20H29NO4/c1-14(2)24-20(22)21-11-10-16(13-21)15-8-9-18(23-3)19(12-15)25-17-6-4-5-7-17/h8-9,12,14,16-17H,4-7,10-11,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470754 (CHEMBL288928) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C23H27NO3/c1-26-21-12-11-18(15-22(21)27-20-9-5-6-10-20)19-13-14-24(16-19)23(25)17-7-3-2-4-8-17/h2-4,7-8,11-12,15,19-20H,5-6,9-10,13-14,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029951 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@H]1CCN2[C@@H]1COC2=O Show InChI InChI=1S/C18H23NO4/c1-21-16-7-6-12(10-17(16)23-13-4-2-3-5-13)14-8-9-19-15(14)11-22-18(19)20/h6-7,10,13-15H,2-5,8-9,11H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470725 (CHEMBL36318) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)c1cccs1 Show InChI InChI=1S/C21H25NO3S/c1-24-18-9-8-15(13-19(18)25-17-5-2-3-6-17)16-10-11-22(14-16)21(23)20-7-4-12-26-20/h4,7-9,12-13,16-17H,2-3,5-6,10-11,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470743 (CHEMBL422578) Show SMILES CCOC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C19H27NO4/c1-3-23-19(21)20-11-10-15(13-20)14-8-9-17(22-2)18(12-14)24-16-6-4-5-7-16/h8-9,12,15-16H,3-7,10-11,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120357 (3-((S)-8-Chloro-6-pyridin-2-yl-4H-3,5,10b-triaza-b...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2-n2ccnc12 |t:7| Show InChI InChI=1S/C20H17ClN4O2/c1-27-18(26)8-6-16-20-23-10-11-25(20)17-7-5-13(21)12-14(17)19(24-16)15-4-2-3-9-22-15/h2-5,7,9-12,16H,6,8H2,1H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285057 (CHEMBL61876 | tert-butyl 3-(3-cyclopentyloxy-4-met...) Show SMILES COC[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C(=O)OC(C)(C)C Show InChI InChI=1S/C23H35NO5/c1-23(2,3)29-22(25)24-13-17(15-26-4)19(14-24)16-10-11-20(27-5)21(12-16)28-18-8-6-7-9-18/h10-12,17-19H,6-9,13-15H2,1-5H3/t17-,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285041 (CHEMBL301053 | methyl 3-cyano-4-(3-cyclopentyloxy-...) Show SMILES COC(=O)N1C[C@@H](C#N)[C@@H](C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C19H24N2O4/c1-23-17-8-7-13(9-18(17)25-15-5-3-4-6-15)16-12-21(19(22)24-2)11-14(16)10-20/h7-9,14-16H,3-6,11-12H2,1-2H3/t14-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470735 (CHEMBL287687) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(C)=O Show InChI InChI=1S/C18H25NO3/c1-13(20)19-10-9-15(12-19)14-7-8-17(21-2)18(11-14)22-16-5-3-4-6-16/h7-8,11,15-16H,3-6,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470748 (CHEMBL36724 | TCMDC-131880) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C#N Show InChI InChI=1S/C17H22N2O2/c1-20-16-7-6-13(14-8-9-19(11-14)12-18)10-17(16)21-15-4-2-3-5-15/h6-7,10,14-15H,2-5,8-9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470739 (CHEMBL413274) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C=O Show InChI InChI=1S/C17H23NO3/c1-20-16-7-6-13(14-8-9-18(11-14)12-19)10-17(16)21-15-4-2-3-5-15/h6-7,10,12,14-15H,2-5,8-9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120345 (3-[(S)-7-Chloro-5-(2-fluoro-phenyl)-2-methylamino-...) Show SMILES CNC1=Nc2ccc(Cl)cc2C(=N[C@H]1CCC(=O)OC)c1ccccc1F |c:12,t:2| Show InChI InChI=1S/C20H19ClFN3O2/c1-23-20-17(9-10-18(26)27-2)24-19(13-5-3-4-6-15(13)22)14-11-12(21)7-8-16(14)25-20/h3-8,11,17H,9-10H2,1-2H3,(H,23,25)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120358 (3-((S)-8-Chloro-1-methyl-6-pyridin-2-yl-4H-3,5,10b...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2-n2c(C)cnc12 |t:7| Show InChI InChI=1S/C21H19ClN4O2/c1-13-12-24-21-17(7-9-19(27)28-2)25-20(16-5-3-4-10-23-16)15-11-14(22)6-8-18(15)26(13)21/h3-6,8,10-12,17H,7,9H2,1-2H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470727 (CHEMBL2093097) Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CCN(C1)C(N)=O |r| Show InChI InChI=1S/C17H24N2O3/c1-21-15-7-6-12(13-8-9-19(11-13)17(18)20)10-16(15)22-14-4-2-3-5-14/h6-7,10,13-14H,2-5,8-9,11H2,1H3,(H2,18,20)/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470755 (CHEMBL36626) Show SMILES COC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C18H25NO4/c1-21-16-8-7-13(11-17(16)23-15-5-3-4-6-15)14-9-10-19(12-14)18(20)22-2/h7-8,11,14-15H,3-6,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120354 (3-((S)-8-Chloro-1,2-dimethyl-6-pyridin-2-yl-4H-3,5...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2-n2c(C)c(C)nc12 |t:7| Show InChI InChI=1S/C22H21ClN4O2/c1-13-14(2)27-19-9-7-15(23)12-16(19)21(17-6-4-5-11-24-17)26-18(22(27)25-13)8-10-20(28)29-3/h4-7,9,11-12,18H,8,10H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120347 (3-((S)-7-Chloro-2-oxo-5-pyridin-2-yl-2,3-dihydro-1...) Show SMILES COC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2NC1=O |t:7| Show InChI InChI=1S/C18H16ClN3O3/c1-25-16(23)8-7-15-18(24)22-13-6-5-11(19)10-12(13)17(21-15)14-4-2-3-9-20-14/h2-6,9-10,15H,7-8H2,1H3,(H,22,24)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470749 (CHEMBL34846) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)N(C)C Show InChI InChI=1S/C19H28N2O3/c1-20(2)19(22)21-11-10-15(13-21)14-8-9-17(23-3)18(12-14)24-16-6-4-5-7-16/h8-9,12,15-16H,4-7,10-11,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50120349 (3-[(S)-7-Chloro-2-ethylamino-5-(2-fluoro-phenyl)-3...) Show SMILES CCNC1=Nc2ccc(Cl)cc2C(=N[C@H]1CCC(=O)OC)c1ccccc1F |c:13,t:3| Show InChI InChI=1S/C21H21ClFN3O2/c1-3-24-21-18(10-11-19(27)28-2)25-20(14-6-4-5-7-16(14)23)15-12-13(22)8-9-17(15)26-21/h4-9,12,18H,3,10-11H2,1-2H3,(H,24,26)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor				Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285049 ((3S,4R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrr...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1C(O)=O)C(=O)OC(C)(C)C Show InChI InChI=1S/C22H31NO6/c1-22(2,3)29-21(26)23-12-16(17(13-23)20(24)25)14-9-10-18(27-4)19(11-14)28-15-7-5-6-8-15/h9-11,15-17H,5-8,12-13H2,1-4H3,(H,24,25)/t16-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470729 (CHEMBL284970) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(S)=N Show InChI InChI=1S/C17H24N2O2S/c1-20-15-7-6-12(13-8-9-19(11-13)17(18)22)10-16(15)21-14-4-2-3-5-14/h6-7,10,13-14H,2-5,8-9,11H2,1H3,(H2,18,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470730 (CHEMBL35213) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H30N2O3/c1-28-22-12-11-19(15-23(22)29-21-9-5-6-10-21)20-13-14-26(17-20)24(27)25-16-18-7-3-2-4-8-18/h2-4,7-8,11-12,15,20-21H,5-6,9-10,13-14,16-17H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470751 (CHEMBL286391) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)C(N)=O Show InChI InChI=1S/C18H24N2O4/c1-23-15-7-6-12(10-16(15)24-14-4-2-3-5-14)13-8-9-20(11-13)18(22)17(19)21/h6-7,10,13-14H,2-5,8-9,11H2,1H3,(H2,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50048243 ((3S,4R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrr...) Show SMILES COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C(=O)OC Show InChI InChI=1S/C20H27NO6/c1-24-17-9-8-13(10-18(17)27-14-6-4-5-7-14)15-11-21(20(23)26-3)12-16(15)19(22)25-2/h8-10,14-16H,4-7,11-12H2,1-3H3/t15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470737 (CHEMBL290191) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C25H28N2O3/c1-29-23-11-10-17(15-24(23)30-20-7-3-4-8-20)19-12-13-27(16-19)25(28)22-14-18-6-2-5-9-21(18)26-22/h2,5-6,9-11,14-15,19-20,26H,3-4,7-8,12-13,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470738 (CHEMBL36728) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(N)=O Show InChI InChI=1S/C17H24N2O3/c1-21-15-7-6-12(13-8-9-19(11-13)17(18)20)10-16(15)22-14-4-2-3-5-14/h6-7,10,13-14H,2-5,8-9,11H2,1H3,(H2,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470726 (CHEMBL1169563) Show SMILES COC(=O)N1CC[C@H](C1)c1ccc(OC)c(OC2CCCC2)c1 |r| Show InChI InChI=1S/C18H25NO4/c1-21-16-8-7-13(11-17(16)23-15-5-3-4-6-15)14-9-10-19(12-14)18(20)22-2/h7-8,11,14-15H,3-6,9-10,12H2,1-2H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285061 (CHEMBL61856 | tert-butyl 3-carbamoyl-4-(3-cyclopen...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1C(N)=O)C(=O)OC(C)(C)C Show InChI InChI=1S/C22H32N2O5/c1-22(2,3)29-21(26)24-12-16(17(13-24)20(23)25)14-9-10-18(27-4)19(11-14)28-15-7-5-6-8-15/h9-11,15-17H,5-8,12-13H2,1-4H3,(H2,23,25)/t16-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470747 (CHEMBL38219) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)C#CC Show InChI InChI=1S/C20H25NO3/c1-3-6-20(22)21-12-11-16(14-21)15-9-10-18(23-2)19(13-15)24-17-7-4-5-8-17/h9-10,13,16-17H,4-5,7-8,11-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair

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