Compile Data Set for Download or QSAR

Found 920 hits with Last Name = 'szewczak' and Initial = 'aa'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275943 (6-(2-(2-amino-2-oxoethyl)-2,8-diazaspiro[4.5]decan...) Show SMILES NC(=O)CN1CCC2(C1)CCN(CC2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C26H30N6O2S/c27-20-5-3-18(22-2-1-13-35-22)14-21(20)30-25(34)19-4-6-24(29-15-19)32-11-8-26(9-12-32)7-10-31(17-26)16-23(28)33/h1-6,13-15H,7-12,16-17,27H2,(H2,28,33)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275941 (CHEMBL513250 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCN(CCO)C2)CC1)-c1cccs1 Show InChI InChI=1S/C26H31N5O2S/c27-21-5-3-19(23-2-1-15-34-23)16-22(21)29-25(33)20-4-6-24(28-17-20)31-11-8-26(9-12-31)7-10-30(18-26)13-14-32/h1-6,15-17,32H,7-14,18,27H2,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275886 (8-(5-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)pyr...) Show SMILES CCNC(=O)N1CCC2(C1)CCN(CC2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C27H32N6O2S/c1-2-29-26(35)33-14-11-27(18-33)9-12-32(13-10-27)24-8-6-20(17-30-24)25(34)31-22-16-19(5-7-21(22)28)23-4-3-15-36-23/h3-8,15-17H,2,9-14,18,28H2,1H3,(H,29,35)(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275769 (CHEMBL471824 | N-(4-aminobiphenyl-3-yl)-6-(2,8-dia...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCNC2)CC1)-c1ccccc1 Show InChI InChI=1S/C26H29N5O/c27-22-8-6-20(19-4-2-1-3-5-19)16-23(22)30-25(32)21-7-9-24(29-17-21)31-14-11-26(12-15-31)10-13-28-18-26/h1-9,16-17,28H,10-15,18,27H2,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016945 (CHEMBL3286736) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)O2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H24FN5O3/c26-19-5-1-16(2-6-19)17-3-7-20(27)21(13-17)30-23(32)18-4-8-22(28-14-18)31-11-9-25(10-12-31)15-29-24(33)34-25/h1-8,13-14H,9-12,15,27H2,(H,29,33)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275888 (CHEMBL470798 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCN(C2)c2ncccn2)CC1)-c1cccs1 Show InChI InChI=1S/C28H29N7OS/c29-22-6-4-20(24-3-1-16-37-24)17-23(22)33-26(36)21-5-7-25(32-18-21)34-13-8-28(9-14-34)10-15-35(19-28)27-30-11-2-12-31-27/h1-7,11-12,16-18H,8-10,13-15,19,29H2,(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275770 (CHEMBL513568 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCNC2)CC1)-c1cccs1 Show InChI InChI=1S/C24H27N5OS/c25-19-5-3-17(21-2-1-13-31-21)14-20(19)28-23(30)18-4-6-22(27-15-18)29-11-8-24(9-12-29)7-10-26-16-24/h1-6,13-15,26H,7-12,16,25H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275824 (CHEMBL511797 | N-(2-amino-5-(thiophen-3-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCNC2)CC1)-c1ccsc1 Show InChI InChI=1S/C24H27N5OS/c25-20-3-1-17(19-5-12-31-15-19)13-21(20)28-23(30)18-2-4-22(27-14-18)29-10-7-24(8-11-29)6-9-26-16-24/h1-5,12-15,26H,6-11,16,25H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275710 (CHEMBL486738 | N-(2-aminophenyl)-6-(2,3-dihydro-1H...) Show SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CC1)CNCc1ccccc21 Show InChI InChI=1S/C25H27N5O/c26-21-7-3-4-8-22(21)29-24(31)19-9-10-23(28-16-19)30-13-11-25(12-14-30)17-27-15-18-5-1-2-6-20(18)25/h1-10,16,27H,11-15,17,26H2,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275940 (CHEMBL472261 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCN(CC(F)(F)F)C2)CC1)-c1cccs1 Show InChI InChI=1S/C26H28F3N5OS/c27-26(28,29)17-33-10-7-25(16-33)8-11-34(12-9-25)23-6-4-19(15-31-23)24(35)32-21-14-18(3-5-20(21)30)22-2-1-13-36-22/h1-6,13-15H,7-12,16-17,30H2,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114806 (CHEMBL3609752) Show SMILES COc1cc(ccc1-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O)-n1cnc(C)c1 |r| Show InChI InChI=1S/C25H22F4N6O2/c1-15-11-33(14-30-15)16-6-7-18(23(10-16)37-2)20-12-35(32-31-20)22-9-8-17-19(26)4-3-5-21(17)34(24(22)36)13-25(27,28)29/h3-7,10-12,14,22H,8-9,13H2,1-2H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114807 (CHEMBL3608385) Show SMILES Cc1cn(cn1)-c1ccc(cc1OCC(F)(F)F)-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O |r| Show InChI InChI=1S/C26H21F7N6O2/c1-15-10-37(14-34-15)21-7-5-16(9-23(21)41-13-26(31,32)33)19-11-39(36-35-19)22-8-6-17-18(27)3-2-4-20(17)38(24(22)40)12-25(28,29)30/h2-5,7,9-11,14,22H,6,8,12-13H2,1H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016943 (CHEMBL3286734) Show SMILES Cc1csc(c1)-c1ccc(N)c(NC(=O)c2ccc(nc2)N2CCC3(CNC(=O)O3)CC2)c1 Show InChI InChI=1S/C24H25N5O3S/c1-15-10-20(33-13-15)16-2-4-18(25)19(11-16)28-22(30)17-3-5-21(26-12-17)29-8-6-24(7-9-29)14-27-23(31)32-24/h2-5,10-13H,6-9,14,25H2,1H3,(H,27,31)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275984 (6-(7-acetyl-2,7-diazaspiro[4.4]nonan-2-yl)-N-(2-am...) Show SMILES CC(=O)N1CCC2(CCN(C2)c2ccc(cn2)C(=O)Nc2cc(ccc2N)-c2cccs2)C1 Show InChI InChI=1S/C25H27N5O2S/c1-17(31)29-10-8-25(15-29)9-11-30(16-25)23-7-5-19(14-27-23)24(32)28-21-13-18(4-6-20(21)26)22-3-2-12-33-22/h2-7,12-14H,8-11,15-16,26H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114800 (CHEMBL3609749) Show SMILES COc1cc(ccc1-n1cnc(C)c1)-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O |r| Show InChI InChI=1S/C25H22F4N6O2/c1-15-11-33(14-30-15)21-8-6-16(10-23(21)37-2)19-12-35(32-31-19)22-9-7-17-18(26)4-3-5-20(17)34(24(22)36)13-25(27,28)29/h3-6,8,10-12,14,22H,7,9,13H2,1-2H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275942 (2-(8-(5-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCN(CC(O)=O)C2)CC1)-c1cccs1 Show InChI InChI=1S/C26H29N5O3S/c27-20-5-3-18(22-2-1-13-35-22)14-21(20)29-25(34)19-4-6-23(28-15-19)31-11-8-26(9-12-31)7-10-30(17-26)16-24(32)33/h1-6,13-15H,7-12,16-17,27H2,(H,29,34)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114836 (CHEMBL3608387) Show SMILES COc1c(F)c(ccc1-n1cnc(C)c1)-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O |r| Show InChI InChI=1S/C25H21F5N6O2/c1-14-10-34(13-31-14)20-8-7-16(22(27)23(20)38-2)18-11-36(33-32-18)21-9-6-15-17(26)4-3-5-19(15)35(24(21)37)12-25(28,29)30/h3-5,7-8,10-11,13,21H,6,9,12H2,1-2H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016944 (CHEMBL3286735) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)O2)CC1)-c1ccccc1 Show InChI InChI=1S/C25H25N5O3/c26-20-8-6-18(17-4-2-1-3-5-17)14-21(20)29-23(31)19-7-9-22(27-15-19)30-12-10-25(11-13-30)16-28-24(32)33-25/h1-9,14-15H,10-13,16,26H2,(H,28,32)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114805 (CHEMBL3608384) Show SMILES Cc1cn(cn1)-c1ccc(cc1)-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O |r| Show InChI InChI=1S/C24H20F4N6O/c1-15-11-32(14-29-15)17-7-5-16(6-8-17)20-12-34(31-30-20)22-10-9-18-19(25)3-2-4-21(18)33(23(22)35)13-24(26,27)28/h2-8,11-12,14,22H,9-10,13H2,1H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275986 (6-(2-acetyl-2,7-diazaspiro[4.5]decan-7-yl)-N-(2-am...) Show SMILES CC(=O)N1CCC2(C1)CCCN(C2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C26H29N5O2S/c1-18(32)30-12-10-26(16-30)9-3-11-31(17-26)24-8-6-20(15-28-24)25(33)29-22-14-19(5-7-21(22)27)23-4-2-13-34-23/h2,4-8,13-15H,3,9-12,16-17,27H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275887 (CHEMBL470582 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES CS(=O)(=O)N1CCC2(C1)CCN(CC2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C25H29N5O3S2/c1-35(32,33)30-13-10-25(17-30)8-11-29(12-9-25)23-7-5-19(16-27-23)24(31)28-21-15-18(4-6-20(21)26)22-3-2-14-34-22/h2-7,14-16H,8-13,17,26H2,1H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275985 (6-(2-acetyl-2,7-diazaspiro[3.5]nonan-7-yl)-N-(2-am...) Show SMILES CC(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C25H27N5O2S/c1-17(31)30-15-25(16-30)8-10-29(11-9-25)23-7-5-19(14-27-23)24(32)28-21-13-18(4-6-20(21)26)22-3-2-12-33-22/h2-7,12-14H,8-11,15-16,26H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275362 (CHEMBL521193 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CC1)N(CNC2=O)c1ccccc1)-c1cccs1 Show InChI InChI=1S/C29H28N6O2S/c30-23-10-8-20(25-7-4-16-38-25)17-24(23)33-27(36)21-9-11-26(31-18-21)34-14-12-29(13-15-34)28(37)32-19-35(29)22-5-2-1-3-6-22/h1-11,16-18H,12-15,19,30H2,(H,32,37)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114837 (CHEMBL3609755) Show SMILES COc1c(F)c(ccc1-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O)-n1cnc(C)c1 |r| Show InChI InChI=1S/C25H21F5N6O2/c1-14-10-34(13-31-14)20-8-7-16(23(38-2)22(20)27)18-11-36(33-32-18)21-9-6-15-17(26)4-3-5-19(15)35(24(21)37)12-25(28,29)30/h3-5,7-8,10-11,13,21H,6,9,12H2,1-2H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276077 (CHEMBL469950 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CC1)NCNC2=O)-c1cccs1 Show InChI InChI=1S/C23H24N6O2S/c24-17-5-3-15(19-2-1-11-32-19)12-18(17)28-21(30)16-4-6-20(25-13-16)29-9-7-23(8-10-29)22(31)26-14-27-23/h1-6,11-13,27H,7-10,14,24H2,(H,26,31)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114810 (CHEMBL3609754) Show SMILES Cc1cn(cn1)-c1ccc(-c2cn(nn2)[C@H]2CCc3c(F)cccc3N(CC(F)(F)F)C2=O)c(F)c1 |r| Show InChI InChI=1S/C24H19F5N6O/c1-14-10-33(13-30-14)15-5-6-16(19(26)9-15)20-11-35(32-31-20)22-8-7-17-18(25)3-2-4-21(17)34(23(22)36)12-24(27,28)29/h2-6,9-11,13,22H,7-8,12H2,1H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276028 (CHEMBL469514 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCNC2=O)CC1)-c1cccs1 Show InChI InChI=1S/C24H25N5O2S/c25-18-5-3-16(20-2-1-13-32-20)14-19(18)28-22(30)17-4-6-21(27-15-17)29-11-8-24(9-12-29)7-10-26-23(24)31/h1-6,13-15H,7-12,25H2,(H,26,31)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276075 (CHEMBL511984 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)C2)CC1)-c1cccs1 Show InChI InChI=1S/C24H25N5O2S/c25-18-5-3-16(20-2-1-11-32-20)12-19(18)28-23(31)17-4-6-21(26-14-17)29-9-7-24(8-10-29)13-22(30)27-15-24/h1-6,11-12,14H,7-10,13,15,25H2,(H,27,30)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276076 (CHEMBL513027 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CC1)NC(=O)NC2=O)-c1cccs1 Show InChI InChI=1S/C23H22N6O3S/c24-16-5-3-14(18-2-1-11-33-18)12-17(16)26-20(30)15-4-6-19(25-13-15)29-9-7-23(8-10-29)21(31)27-22(32)28-23/h1-6,11-13H,7-10,24H2,(H,26,30)(H2,27,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276027 (CHEMBL470148 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCCC2O)CC1)-c1cccs1 Show InChI InChI=1S/C25H28N4O2S/c26-19-7-5-17(21-3-2-14-32-21)15-20(19)28-24(31)18-6-8-23(27-16-18)29-12-10-25(11-13-29)9-1-4-22(25)30/h2-3,5-8,14-16,22,30H,1,4,9-13,26H2,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275885 (6-(2-acetyl-2,8-diazaspiro[4.5]decan-8-yl)-N-(2-am...) Show SMILES CC(=O)N1CCC2(C1)CCN(CC2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C26H29N5O2S/c1-18(32)31-13-10-26(17-31)8-11-30(12-9-26)24-7-5-20(16-28-24)25(33)29-22-15-19(4-6-21(22)27)23-3-2-14-34-23/h2-7,14-16H,8-13,17,27H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275827 (CHEMBL472252 | N-(2-amino-5-(1-methyl-1H-imidazol-...) Show SMILES Cn1cnc(c1)-c1ccc(N)c(NC(=O)c2ccc(nc2)N2CCC3(CCNC3)CC2)c1 Show InChI InChI=1S/C24H29N7O/c1-30-14-21(28-16-30)17-2-4-19(25)20(12-17)29-23(32)18-3-5-22(27-13-18)31-10-7-24(8-11-31)6-9-26-15-24/h2-5,12-14,16,26H,6-11,15,25H2,1H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275826 (CHEMBL472251 | N-(2-amino-5-(1H-pyrazol-3-yl)pheny...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCNC2)CC1)-c1cc[nH]n1 Show InChI InChI=1S/C23H27N7O/c24-18-3-1-16(19-5-9-27-29-19)13-20(18)28-22(31)17-2-4-21(26-14-17)30-11-7-23(8-12-30)6-10-25-15-23/h1-5,9,13-14,25H,6-8,10-12,15,24H2,(H,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016947 (CHEMBL3286738) Show SMILES Cn1cnc(c1)-c1ccc(N)c(NC(=O)c2ccc(nc2)N2CCC3(CNC(=O)O3)CC2)c1 Show InChI InChI=1S/C23H25N7O3/c1-29-12-19(27-14-29)15-2-4-17(24)18(10-15)28-21(31)16-3-5-20(25-11-16)30-8-6-23(7-9-30)13-26-22(32)33-23/h2-5,10-12,14H,6-9,13,24H2,1H3,(H,26,32)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016948 (CHEMBL3286739) Show SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)O2)CC1 Show InChI InChI=1S/C19H21N5O3/c20-14-3-1-2-4-15(14)23-17(25)13-5-6-16(21-11-13)24-9-7-19(8-10-24)12-22-18(26)27-19/h1-6,11H,7-10,12,20H2,(H,22,26)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275364 (CHEMBL486770 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(COC(=O)N2)CC1)-c1cccs1 Show InChI InChI=1S/C23H23N5O3S/c24-17-5-3-15(19-2-1-11-32-19)12-18(17)26-21(29)16-4-6-20(25-13-16)28-9-7-23(8-10-28)14-31-22(30)27-23/h1-6,11-13H,7-10,14,24H2,(H,26,29)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016946 (CHEMBL3286737) Show SMILES Cn1cc(cn1)-c1ccc(N)c(NC(=O)c2ccc(nc2)N2CCC3(CNC(=O)O3)CC2)c1 Show InChI InChI=1S/C23H25N7O3/c1-29-13-17(12-27-29)15-2-4-18(24)19(10-15)28-21(31)16-3-5-20(25-11-16)30-8-6-23(7-9-30)14-26-22(32)33-23/h2-5,10-13H,6-9,14,24H2,1H3,(H,26,32)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276026 (CHEMBL470147 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCCC2=O)CC1)-c1cccs1 Show InChI InChI=1S/C25H26N4O2S/c26-19-7-5-17(21-3-2-14-32-21)15-20(19)28-24(31)18-6-8-23(27-16-18)29-12-10-25(11-13-29)9-1-4-22(25)30/h2-3,5-8,14-16H,1,4,9-13,26H2,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276025 (CHEMBL511625 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNc3ccccc23)CC1)-c1cccs1 Show InChI InChI=1S/C28H27N5OS/c29-22-9-7-19(25-6-3-15-35-25)16-24(22)32-27(34)20-8-10-26(30-17-20)33-13-11-28(12-14-33)18-31-23-5-2-1-4-21(23)28/h1-10,15-17,31H,11-14,18,29H2,(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276074 (CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC2=O)CC1)-c1cccs1 Show InChI InChI=1S/C23H23N5O2S/c24-17-5-3-15(19-2-1-11-31-19)12-18(17)27-21(29)16-4-6-20(25-13-16)28-9-7-23(8-10-28)14-26-22(23)30/h1-6,11-13H,7-10,14,24H2,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275363 (CHEMBL486152 | N-(2-amino-5-(thiophen-2-yl)phenyl)...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)N2)CC1)-c1cccs1 Show InChI InChI=1S/C23H24N6O2S/c24-17-5-3-15(19-2-1-11-32-19)12-18(17)27-21(30)16-4-6-20(25-13-16)29-9-7-23(8-10-29)14-26-22(31)28-23/h1-6,11-13H,7-10,14,24H2,(H,27,30)(H2,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275987 (6-(1-acetyl-1,8-diazaspiro[4.5]decan-8-yl)-N-(2-am...) Show SMILES CC(=O)N1CCCC11CCN(CC1)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C26H29N5O2S/c1-18(32)31-12-3-9-26(31)10-13-30(14-11-26)24-8-6-20(17-28-24)25(33)29-22-16-19(5-7-21(22)27)23-4-2-15-34-23/h2,4-8,15-17H,3,9-14,27H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275709 (CHEMBL520050 | N-(2-aminophenyl)-6-(spiro[indoline...) Show SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CNc3ccccc23)CC1 Show InChI InChI=1S/C24H25N5O/c25-19-6-2-4-8-21(19)28-23(30)17-9-10-22(26-15-17)29-13-11-24(12-14-29)16-27-20-7-3-1-5-18(20)24/h1-10,15,27H,11-14,16,25H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50114845 (CHEMBL3609759) Show SMILES COc1cc(ccc1-n1cnc(C)n1)-c1cn(nn1)[C@H]1CCc2c(F)cccc2N(CC(F)(F)F)C1=O |r| Show InChI InChI=1S/C24H21F4N7O2/c1-14-29-13-35(31-14)20-8-6-15(10-22(20)37-2)18-11-34(32-30-18)21-9-7-16-17(25)4-3-5-19(16)33(23(21)36)12-24(26,27)28/h3-6,8,10-11,13,21H,7,9,12H2,1-2H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem Lett 25: 3495-500 (2015) Article DOI: 10.1016/j.bmcl.2015.06.032 BindingDB Entry DOI: 10.7270/Q2125VFP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275825 (CHEMBL470156 | N-(2-amino-5-(1-methyl-1H-pyrazol-4...) Show SMILES Cn1cc(cn1)-c1ccc(N)c(NC(=O)c2ccc(nc2)N2CCC3(CCNC3)CC2)c1 Show InChI InChI=1S/C24H29N7O/c1-30-15-19(14-28-30)17-2-4-20(25)21(12-17)29-23(32)18-3-5-22(27-13-18)31-10-7-24(8-11-31)6-9-26-16-24/h2-5,12-15,26H,6-11,16,25H2,1H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275768 (CHEMBL499776 | N-(2-aminophenyl)-6-(2,8-diazaspiro...) Show SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CCNC2)CC1 Show InChI InChI=1S/C20H25N5O/c21-16-3-1-2-4-17(16)24-19(26)15-5-6-18(23-13-15)25-11-8-20(9-12-25)7-10-22-14-20/h1-6,13,22H,7-12,14,21H2,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50275708 (CHEMBL486737 | N-(2-aminophenyl)-6-(7-(phenylsulfo...) Show SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CCN(C2)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C25H27N5O3S/c26-21-8-4-5-9-22(21)28-24(31)19-10-11-23(27-16-19)29-14-12-25(17-29)13-15-30(18-25)34(32,33)20-6-2-1-3-7-20/h1-11,16H,12-15,17-18,26H2,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 18: 6104-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.052 BindingDB Entry DOI: 10.7270/Q23R0SQ2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016941 (CHEMBL3286732) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)O2)CC1)-c1cccs1 Show InChI InChI=1S/C23H23N5O3S/c24-17-5-3-15(19-2-1-11-32-19)12-18(17)27-21(29)16-4-6-20(25-13-16)28-9-7-23(8-10-28)14-26-22(30)31-23/h1-6,11-13H,7-10,14,24H2,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50220232 ((S)-benzyl 4-(5-((2-aminophenyl)carbamoyl)pyridin-...) Show SMILES C[C@H]1CN(CCN1C(=O)OCc1ccccc1)c1ccc(cn1)C(=O)Nc1ccccc1N |r| Show InChI InChI=1S/C25H27N5O3/c1-18-16-29(13-14-30(18)25(32)33-17-19-7-3-2-4-8-19)23-12-11-20(15-27-23)24(31)28-22-10-6-5-9-21(22)26/h2-12,15,18H,13-14,16-17,26H2,1H3,(H,28,31)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 17: 5300-9 (2007) Article DOI: 10.1016/j.bmcl.2007.08.023 BindingDB Entry DOI: 10.7270/Q2571BQH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50016942 (CHEMBL3286733) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC(=O)O2)CC1)-c1ccsc1 Show InChI InChI=1S/C23H23N5O3S/c24-18-3-1-15(17-5-10-32-13-17)11-19(18)27-21(29)16-2-4-20(25-12-16)28-8-6-23(7-9-28)14-26-22(30)31-23/h1-5,10-13H,6-9,14,24H2,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 5: 340-5 (2014) Article DOI: 10.1021/ml4004233 BindingDB Entry DOI: 10.7270/Q2HH6MM7
					More data for this Ligand-Target Pair

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