Compile Data Set for Download or QSAR

Found 59 hits with Last Name = 'tallant' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448085 (CHEMBL3121323) Show SMILES COc1ncc(cc1NS(=O)(=O)c1cccnc1)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C25H20N6O4S/c1-35-23-22(30-36(33,34)19-8-5-11-27-15-19)13-17(14-28-23)16-9-10-21-20(12-16)24(32)31(25(26)29-21)18-6-3-2-4-7-18/h2-15,30H,1H3,(H2,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448094 (CHEMBL3121314) Show SMILES Nc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C25H18F2N6O3S/c26-16-7-9-22(19(27)12-16)37(35,36)32-21-11-15(13-30-23(21)28)14-6-8-20-18(10-14)24(34)33(25(29)31-20)17-4-2-1-3-5-17/h1-13,32H,(H2,28,30)(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448089 (CHEMBL3121319) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccccc1C)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H23N5O4S/c1-17-8-6-7-11-24(17)37(34,35)31-23-15-19(16-29-25(23)36-2)18-12-13-22-21(14-18)26(33)32(27(28)30-22)20-9-4-3-5-10-20/h3-16,31H,1-2H3,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448086 (CHEMBL3121322) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(cc1)C#N)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H20N6O4S/c1-37-25-24(32-38(35,36)21-10-7-17(15-28)8-11-21)14-19(16-30-25)18-9-12-23-22(13-18)26(34)33(27(29)31-23)20-5-3-2-4-6-20/h2-14,16,32H,1H3,(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448096 (CHEMBL3121334) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C26H19F2N5O4S/c1-37-24-22(32-38(35,36)23-10-8-17(27)13-20(23)28)12-16(14-30-24)15-7-9-21-19(11-15)25(34)33(26(29)31-21)18-5-3-2-4-6-18/h2-14,32H,1H3,(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448103 (CHEMBL3121327) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncnc(N3CCOCC3)c2c1 Show InChI InChI=1S/C24H21F2N5O4S/c1-34-24-21(30-36(32,33)22-5-3-17(25)12-19(22)26)11-16(13-27-24)15-2-4-20-18(10-15)23(29-14-28-20)31-6-8-35-9-7-31/h2-5,10-14,30H,6-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448090 (CHEMBL3121318) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccccc1)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C26H21N5O4S/c1-35-24-23(30-36(33,34)20-10-6-3-7-11-20)15-18(16-28-24)17-12-13-22-21(14-17)25(32)31(26(27)29-22)19-8-4-2-5-9-19/h2-16,30H,1H3,(H2,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448103 (CHEMBL3121327) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncnc(N3CCOCC3)c2c1 Show InChI InChI=1S/C24H21F2N5O4S/c1-34-24-21(30-36(32,33)22-5-3-17(25)12-19(22)26)11-16(13-27-24)15-2-4-20-18(10-15)23(29-14-28-20)31-6-8-35-9-7-31/h2-5,10-14,30H,6-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448096 (CHEMBL3121334) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C26H19F2N5O4S/c1-37-24-22(32-38(35,36)23-10-8-17(27)13-20(23)28)12-16(14-30-24)15-7-9-21-19(11-15)25(34)33(26(29)31-21)18-5-3-2-4-6-18/h2-14,32H,1H3,(H2,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448088 (CHEMBL3121320) Show SMILES COc1ncc(cc1NS(=O)(=O)c1cccc(C)c1)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H23N5O4S/c1-17-7-6-10-21(13-17)37(34,35)31-24-15-19(16-29-25(24)36-2)18-11-12-23-22(14-18)26(33)32(27(28)30-23)20-8-4-3-5-9-20/h3-16,31H,1-2H3,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448097 (CHEMBL3121333) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(nc2c1)-c1ccccc1 Show InChI InChI=1S/C26H19F2N5O3S/c1-36-26-22(33-37(34,35)23-10-8-18(27)13-19(23)28)12-17(14-30-26)16-7-9-20-21(11-16)31-24(25(29)32-20)15-5-3-2-4-6-15/h2-14,33H,1H3,(H2,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448077 (CHEMBL3121308) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.45,-42.76,;17.91,-42.77,;20.21,-41.42,;18.67,-41.43,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-21-9-7-16(28)12-19(21)29)11-15(13-34-24)14-6-8-20-17(10-14)25(38)37(26(33)35-20)22-5-3-2-4-18(22)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448085 (CHEMBL3121323) Show SMILES COc1ncc(cc1NS(=O)(=O)c1cccnc1)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C25H20N6O4S/c1-35-23-22(30-36(33,34)19-8-5-11-27-15-19)13-17(14-28-23)16-9-10-21-20(12-16)24(32)31(25(26)29-21)18-6-3-2-4-7-18/h2-15,30H,1H3,(H2,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448084 (CHEMBL3121324) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C26H19F2N5O4S/c1-37-24-23(38(35,36)32-22-10-8-17(27)13-20(22)28)12-16(14-30-24)15-7-9-21-19(11-15)25(34)33(26(29)31-21)18-5-3-2-4-6-18/h2-14,32H,1H3,(H2,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448097 (CHEMBL3121333) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(nc2c1)-c1ccccc1 Show InChI InChI=1S/C26H19F2N5O3S/c1-36-26-22(33-37(34,35)23-10-8-18(27)13-19(23)28)12-17(14-30-26)16-7-9-20-21(11-16)31-24(25(29)32-20)15-5-3-2-4-6-15/h2-14,33H,1H3,(H2,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448082 (CHEMBL3121326) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(C3CCOCC3)c(=O)c2c1 Show InChI InChI=1S/C25H23F2N5O5S/c1-36-23-22(38(34,35)31-21-5-3-16(26)12-19(21)27)11-15(13-29-23)14-2-4-20-18(10-14)24(33)32(25(28)30-20)17-6-8-37-9-7-17/h2-5,10-13,17,31H,6-9H2,1H3,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448079 (CHEMBL3121311) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;18.89,-43.34,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H21F2N5O4S/c1-15-5-3-4-6-23(15)34-26(35)19-11-16(7-9-21(19)32-27(34)30)17-12-24(25(38-2)31-14-17)39(36,37)33-22-10-8-18(28)13-20(22)29/h3-14,33H,1-2H3,(H2,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448087 (CHEMBL3121321) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(C)cc1)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H23N5O4S/c1-17-8-11-21(12-9-17)37(34,35)31-24-15-19(16-29-25(24)36-2)18-10-13-23-22(14-18)26(33)32(27(28)30-23)20-6-4-3-5-7-20/h3-16,31H,1-2H3,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448092 (CHEMBL3121316) Show SMILES COc1ncc(cc1NS(C)(=O)=O)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C21H19N5O4S/c1-30-19-18(25-31(2,28)29)11-14(12-23-19)13-8-9-17-16(10-13)20(27)26(21(22)24-17)15-6-4-3-5-7-15/h3-12,25H,1-2H3,(H2,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448078 (CHEMBL3121312) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(C)C)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.13,-43,;19.52,-41.52,;17.64,-43.41,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C29H25F2N5O4S/c1-16(2)20-6-4-5-7-25(20)36-28(37)21-12-17(8-10-23(21)34-29(36)32)18-13-26(27(40-3)33-15-18)41(38,39)35-24-11-9-19(30)14-22(24)31/h4-16,35H,1-3H3,(H2,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448083 (CHEMBL3121325) Show SMILES CCn1c(N)nc2ccc(cc2c1=O)-c1cnc(OC)c(c1)S(=O)(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C22H19F2N5O4S/c1-3-29-21(30)15-8-12(4-6-17(15)27-22(29)25)13-9-19(20(33-2)26-11-13)34(31,32)28-18-7-5-14(23)10-16(18)24/h4-11,28H,3H2,1-2H3,(H2,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448089 (CHEMBL3121319) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccccc1C)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H23N5O4S/c1-17-8-6-7-11-24(17)37(34,35)31-23-15-19(16-29-25(23)36-2)18-12-13-22-21(14-18)26(33)32(27(28)30-22)20-9-4-3-5-10-20/h3-16,31H,1-2H3,(H2,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448102 (CHEMBL3121328) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(cc2c1)-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C31H27F2N5O4S/c1-41-31-28(37-43(39,40)29-9-5-23(32)17-26(29)33)16-22(18-35-31)20-4-8-27-21(14-20)15-25(30(34)36-27)19-2-6-24(7-3-19)38-10-12-42-13-11-38/h2-9,14-18,37H,10-13H2,1H3,(H2,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448080 (CHEMBL3121310) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccc(cc3)C(F)(F)F)c(=O)c2c1 Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-22-9-5-17(28)12-20(22)29)11-15(13-34-24)14-2-8-21-19(10-14)25(38)37(26(33)35-21)18-6-3-16(4-7-18)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448088 (CHEMBL3121320) Show SMILES COc1ncc(cc1NS(=O)(=O)c1cccc(C)c1)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H23N5O4S/c1-17-7-6-10-21(13-17)37(34,35)31-24-15-19(16-29-25(24)36-2)18-11-12-23-22(14-18)26(33)32(27(28)30-23)20-8-4-3-5-9-20/h3-16,31H,1-2H3,(H2,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448086 (CHEMBL3121322) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(cc1)C#N)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H20N6O4S/c1-37-25-24(32-38(35,36)21-10-7-17(15-28)8-11-21)14-19(16-30-25)18-9-12-23-22(13-18)26(34)33(27(29)31-23)20-5-3-2-4-6-20/h2-14,16,32H,1H3,(H2,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448081 (CHEMBL3121309) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3cccc(c3)C(F)(F)F)c(=O)c2c1 Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-22-8-6-17(28)12-20(22)29)10-15(13-34-24)14-5-7-21-19(9-14)25(38)37(26(33)35-21)18-4-2-3-16(11-18)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448101 (CHEMBL3121329) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C27H20F2N4O3S/c1-36-27-24(33-37(34,35)25-10-8-20(28)14-22(25)29)13-19(15-31-27)17-7-9-23-18(11-17)12-21(26(30)32-23)16-5-3-2-4-6-16/h2-15,33H,1H3,(H2,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448101 (CHEMBL3121329) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C27H20F2N4O3S/c1-36-27-24(33-37(34,35)25-10-8-20(28)14-22(25)29)13-19(15-31-27)17-7-9-23-18(11-17)12-21(26(30)32-23)16-5-3-2-4-6-16/h2-15,33H,1H3,(H2,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448077 (CHEMBL3121308) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.45,-42.76,;17.91,-42.77,;20.21,-41.42,;18.67,-41.43,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-21-9-7-16(28)12-19(21)29)11-15(13-34-24)14-6-8-20-17(10-14)25(38)37(26(33)35-20)22-5-3-2-4-18(22)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448091 (CHEMBL3121317) Show SMILES COc1ncc(cc1NS(=O)(=O)C(C)C)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C23H23N5O4S/c1-14(2)33(30,31)27-20-12-16(13-25-21(20)32-3)15-9-10-19-18(11-15)22(29)28(23(24)26-19)17-7-5-4-6-8-17/h4-14,27H,1-3H3,(H2,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448077 (CHEMBL3121308) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.45,-42.76,;17.91,-42.77,;20.21,-41.42,;18.67,-41.43,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-21-9-7-16(28)12-19(21)29)11-15(13-34-24)14-6-8-20-17(10-14)25(38)37(26(33)35-20)22-5-3-2-4-18(22)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448083 (CHEMBL3121325) Show SMILES CCn1c(N)nc2ccc(cc2c1=O)-c1cnc(OC)c(c1)S(=O)(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C22H19F2N5O4S/c1-3-29-21(30)15-8-12(4-6-17(15)27-22(29)25)13-9-19(20(33-2)26-11-13)34(31,32)28-18-7-5-14(23)10-16(18)24/h4-11,28H,3H2,1-2H3,(H2,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448099 (CHEMBL3121331) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc2cc(c(N)nc2cn1)-c1ccccc1 Show InChI InChI=1S/C26H19F2N5O3S/c1-36-26-22(33-37(34,35)24-8-7-18(27)12-20(24)28)11-17(13-31-26)21-10-16-9-19(15-5-3-2-4-6-15)25(29)32-23(16)14-30-21/h2-14,33H,1H3,(H2,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448095 (CHEMBL3121313) Show SMILES COc1ccc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H20F2N4O4S/c1-37-24-11-8-17(14-23(24)32-38(35,36)25-12-9-18(28)15-21(25)29)16-7-10-22-20(13-16)26(34)33(27(30)31-22)19-5-3-2-4-6-19/h2-15,32H,1H3,(H2,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448079 (CHEMBL3121311) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;18.89,-43.34,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H21F2N5O4S/c1-15-5-3-4-6-23(15)34-26(35)19-11-16(7-9-21(19)32-27(34)30)17-12-24(25(38-2)31-14-17)39(36,37)33-22-10-8-18(28)13-20(22)29/h3-14,33H,1-2H3,(H2,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448095 (CHEMBL3121313) Show SMILES COc1ccc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C27H20F2N4O4S/c1-37-24-11-8-17(14-23(24)32-38(35,36)25-12-9-18(28)15-21(25)29)16-7-10-22-20(13-16)26(34)33(27(30)31-22)19-5-3-2-4-6-19/h2-15,32H,1H3,(H2,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448080 (CHEMBL3121310) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccc(cc3)C(F)(F)F)c(=O)c2c1 Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-22-9-5-17(28)12-20(22)29)11-15(13-34-24)14-2-8-21-19(10-14)25(38)37(26(33)35-21)18-6-3-16(4-7-18)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448091 (CHEMBL3121317) Show SMILES COc1ncc(cc1NS(=O)(=O)C(C)C)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C23H23N5O4S/c1-14(2)33(30,31)27-20-12-16(13-25-21(20)32-3)15-9-10-19-18(11-15)22(29)28(23(24)26-19)17-7-5-4-6-8-17/h4-14,27H,1-3H3,(H2,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448082 (CHEMBL3121326) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(C3CCOCC3)c(=O)c2c1 Show InChI InChI=1S/C25H23F2N5O5S/c1-36-23-22(38(34,35)31-21-5-3-16(26)12-19(21)27)11-15(13-29-23)14-2-4-20-18(10-14)24(33)32(25(28)30-20)17-6-8-37-9-7-17/h2-5,10-13,17,31H,6-9H2,1H3,(H2,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50448100 (CHEMBL3121330) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cnc2nc(N)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C26H19F2N5O3S/c1-36-26-22(33-37(34,35)23-8-7-19(27)12-21(23)28)11-18(14-31-26)17-9-16-10-20(15-5-3-2-4-6-15)24(29)32-25(16)30-13-17/h2-14,33H,1H3,(H2,29,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448102 (CHEMBL3121328) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(cc2c1)-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C31H27F2N5O4S/c1-41-31-28(37-43(39,40)29-9-5-23(32)17-26(29)33)16-22(18-35-31)20-4-8-27-21(14-20)15-25(30(34)36-27)19-2-6-24(7-3-19)38-10-12-42-13-11-38/h2-9,14-18,37H,10-13H2,1H3,(H2,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448092 (CHEMBL3121316) Show SMILES COc1ncc(cc1NS(C)(=O)=O)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C21H19N5O4S/c1-30-19-18(25-31(2,28)29)11-14(12-23-19)13-8-9-17-16(10-13)20(27)26(21(22)24-17)15-6-4-3-5-7-15/h3-12,25H,1-2H3,(H2,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448078 (CHEMBL3121312) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(C)C)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.13,-43,;19.52,-41.52,;17.64,-43.41,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C29H25F2N5O4S/c1-16(2)20-6-4-5-7-25(20)36-28(37)21-12-17(8-10-23(21)34-29(36)32)18-13-26(27(40-3)33-15-18)41(38,39)35-24-11-9-19(30)14-22(24)31/h4-16,35H,1-3H3,(H2,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448084 (CHEMBL3121324) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3)c(=O)c2c1 Show InChI InChI=1S/C26H19F2N5O4S/c1-37-24-23(38(35,36)32-22-10-8-17(27)13-20(22)28)12-16(14-30-24)15-7-9-21-19(11-15)25(34)33(26(29)31-21)18-5-3-2-4-6-18/h2-14,32H,1H3,(H2,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448099 (CHEMBL3121331) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc2cc(c(N)nc2cn1)-c1ccccc1 Show InChI InChI=1S/C26H19F2N5O3S/c1-36-26-22(33-37(34,35)24-8-7-18(27)12-20(24)28)11-17(13-31-26)21-10-16-9-19(15-5-3-2-4-6-15)25(29)32-23(16)14-30-21/h2-14,33H,1H3,(H2,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448081 (CHEMBL3121309) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3cccc(c3)C(F)(F)F)c(=O)c2c1 Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-22-8-6-17(28)12-20(22)29)10-15(13-34-24)14-5-7-21-19(9-14)25(38)37(26(33)35-21)18-4-2-3-16(11-18)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448077 (CHEMBL3121308) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.45,-42.76,;17.91,-42.77,;20.21,-41.42,;18.67,-41.43,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-21-9-7-16(28)12-19(21)29)11-15(13-34-24)14-6-8-20-17(10-14)25(38)37(26(33)35-20)22-5-3-2-4-18(22)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448077 (CHEMBL3121308) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.45,-42.76,;17.91,-42.77,;20.21,-41.42,;18.67,-41.43,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-21-9-7-16(28)12-19(21)29)11-15(13-34-24)14-6-8-20-17(10-14)25(38)37(26(33)35-20)22-5-3-2-4-18(22)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448077 (CHEMBL3121308) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1 |(6.94,-44.12,;8.27,-43.35,;9.61,-44.12,;9.61,-45.66,;10.94,-46.43,;12.27,-45.66,;12.27,-44.12,;10.94,-43.35,;10.94,-41.8,;12.02,-40.7,;12.43,-42.19,;9.61,-41.03,;9.61,-39.5,;10.94,-38.73,;10.95,-37.19,;9.61,-36.42,;9.62,-34.88,;8.28,-37.18,;8.28,-38.72,;6.94,-39.49,;13.6,-46.43,;13.6,-47.97,;14.93,-48.74,;16.27,-47.96,;17.6,-48.73,;18.94,-47.96,;20.27,-48.72,;18.93,-46.41,;20.25,-45.63,;21.57,-46.4,;22.89,-45.63,;22.89,-44.09,;21.56,-43.33,;20.23,-44.1,;19.45,-42.76,;17.91,-42.77,;20.21,-41.42,;18.67,-41.43,;17.59,-45.65,;17.58,-44.11,;16.27,-46.42,;14.93,-45.66,)| Show InChI InChI=1S/C27H18F5N5O4S/c1-41-24-23(42(39,40)36-21-9-7-16(28)12-19(21)29)11-15(13-34-24)14-6-8-20-17(10-14)25(38)37(26(33)35-20)22-5-3-2-4-18(22)27(30,31)32/h2-13,36H,1H3,(H2,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair

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