Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human)) | BDBM50457815 (CHEMBL4211840) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of NIK (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmc.2020.115856 BindingDB Entry DOI: 10.7270/Q2ZP49QV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human)) | BDBM158654 (US9034866, 129) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of NIK (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmc.2020.115856 BindingDB Entry DOI: 10.7270/Q2ZP49QV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222885 (6-(4-fluorophenoxy)-3-[(1-isopropylpiperidin-3-yl)...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human)) | BDBM158621 (US9034866, 96) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of NIK (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmc.2020.115856 BindingDB Entry DOI: 10.7270/Q2ZP49QV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222867 ((S)-6-(4-fluorophenoxy)-3-((1-isopropylpiperidin-3...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM50433561 (CHEMBL2381408) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.880 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description Binding affinity to MDM2 (unknown origin) | Eur J Med Chem 176: 476-491 (2019) Article DOI: 10.1016/j.ejmech.2019.05.046 BindingDB Entry DOI: 10.7270/Q22J6G6H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222867 ((S)-6-(4-fluorophenoxy)-3-((1-isopropylpiperidin-3...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222875 (6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidi...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM50427703 (CHEMBL2324220) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Curated by ChEMBL | Assay Description Inhibition of human recombinant IDE expressed in CHO cells in presence of [125I]-insulin by HTRF assay | Eur J Med Chem 179: 557-566 (2019) Article DOI: 10.1016/j.ejmech.2019.06.057 BindingDB Entry DOI: 10.7270/Q2XS5ZT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222859 (6-(4-chlorophenyl)-3-{[(3S)-1-ethylpiperidin-3-yl]...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222884 (6-(4-chlorophenyl)-3-[(-1-ethylpiperidin-3-yl)meth...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222873 (6-(4-chlorophenyl)-3-[(1-isopropylpiperidin-3-yl)m...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222863 (6-(4-chlorophenyl)-3-[(1-cyclobutylpiperidin-3-yl)...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222858 (6-(4-fluorophenoxy)-2-isopropyl-3-[(1-isopropylpip...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222879 (6-(4-chlorophenyl)-3-{[1-(2-methoxyethyl)piperidin...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222862 (6-(4-chlorophenyl)-2-(2-methylphenyl)-3-(piperidin...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222881 ((S)-3-((1-ethylpiperidin-3-yl)methyl)-2-o-tolyl-6-...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222853 (6-(4-chlorophenyl)-3-{[1-(2-fluoroethyl)piperidin-...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222887 ((S)-6-(4-chlorophenyl)-3-((1-ethylpiperidin-3-yl)m...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222869 (6-(4-fluorophenoxy)-3-{[(3S)-1-isopropylpiperidin-...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222854 (6-(4-luorophenoxy)-3-{[(3S)-1-isopropylpiperidin-3...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50371160 (CHEMBL243429) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50093349 (CHEMBL3586664 | US9951014, Name 19c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cholinesterase (Equus caballus (Horse)) | BDBM50555654 (CHEMBL4797435) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Mixed inhibition of equine serum BChE using butyrylthiolcholine iodide as substrate by Lineweaver-Burk plot analysis | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112273 BindingDB Entry DOI: 10.7270/Q2T157BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222868 (3-[(1-ethylpiperidin-3-yl)methyl]-2-(2-methylpheny...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50014717 (CHEMBL3262026 | US10759791, Compound 8R | US995101...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of purified rat nNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assay | J Med Chem 57: 4382-96 (2014) Article DOI: 10.1021/jm5004182 BindingDB Entry DOI: 10.7270/Q21R6S26 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222876 (6-(4-chlorophenyl)-3-[(1-ethyl-1,2,5,6-tetrahydrop...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50014715 (CHEMBL3262024 | US10759791, Compound 8 | US9951014...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of purified rat nNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assay | J Med Chem 57: 4382-96 (2014) Article DOI: 10.1021/jm5004182 BindingDB Entry DOI: 10.7270/Q21R6S26 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50093348 (CHEMBL3586663 | US9951014, Name 19b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM152713 (4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50371159 (CHEMBL390274) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222865 (6-(4-fluorophenyl)-2-isopropyl-3-[(1-isopropylpipe...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222883 ((S)-3-((1-ethylpiperidin-3-yl)methyl)-6-(4-fluorop...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222861 (6-(4-chlorophenyl)-2-isopropyl-3-{[(3S)-1-isopropy...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222870 ((R)-6-(4-fluorophenoxy)-3-((1-isopropylpiperidin-3...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50427863 (CHEMBL2326360) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of rat nNOS | J Med Chem 58: 994-1004 (2015) Article DOI: 10.1021/jm501723p BindingDB Entry DOI: 10.7270/Q2833TP5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50014713 (CHEMBL3262022 | US10759791, Compound 6 | US9951014...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of purified rat nNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assay | J Med Chem 57: 4382-96 (2014) Article DOI: 10.1021/jm5004182 BindingDB Entry DOI: 10.7270/Q21R6S26 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50093349 (CHEMBL3586664 | US9951014, Name 19c) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of human recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50093341 (CHEMBL3586658 | US9951014, Name 10c) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of human recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM152712 (4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of human recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cholinesterase (Equus caballus (Horse)) | BDBM50528693 (CHEMBL4513389) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Line weaver Burk reciprocal plot analysis | Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111598 BindingDB Entry DOI: 10.7270/Q24F1V59 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50093341 (CHEMBL3586658 | US9951014, Name 10c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM152713 (4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of human recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50093344 (CHEMBL3586662 | US9951014, Name 19a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assay | J Med Chem 58: 5548-60 (2015) Article DOI: 10.1021/acs.jmedchem.5b00573 BindingDB Entry DOI: 10.7270/Q2319XN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50014710 (CHEMBL3262019 | US10759791, Compound 4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of purified rat nNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assay | J Med Chem 57: 4382-96 (2014) Article DOI: 10.1021/jm5004182 BindingDB Entry DOI: 10.7270/Q21R6S26 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50014716 (CHEMBL3262025 | US10759791, Compound 8S | US995101...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of purified rat nNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assay | J Med Chem 57: 4382-96 (2014) Article DOI: 10.1021/jm5004182 BindingDB Entry DOI: 10.7270/Q21R6S26 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Growth hormone secretagogue receptor type 1 (Ovis aries) | BDBM50222888 (6-(4-chlorophenyl)-3-{[(3R)-1-ethylpiperidin-3-yl]...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay | J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50341678 (6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of rat nNOS | J Med Chem 58: 994-1004 (2015) Article DOI: 10.1021/jm501723p BindingDB Entry DOI: 10.7270/Q2833TP5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50014715 (CHEMBL3262024 | US10759791, Compound 8 | US9951014...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of human nNOS | J Med Chem 57: 4382-96 (2014) Article DOI: 10.1021/jm5004182 BindingDB Entry DOI: 10.7270/Q21R6S26 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
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