Compile Data Set for Download or QSAR

Found 2525 hits with Last Name = 'tars' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1 Show InChI InChI=1S/C33H41ClN6O2/c34-28-12-10-24(11-13-28)18-30(38-31(41)29-19-25-6-4-5-7-26(25)20-36-29)32(42)39-16-14-33(15-17-39,21-40-23-35-22-37-40)27-8-2-1-3-9-27/h4-7,10-13,22-23,27,29-30,36H,1-3,8-9,14-21H2,(H,38,41)/t29?,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity towards Melanocortin 4 receptor using [125I]NDP-MSH				J Med Chem 47: 4613-26 (2004) Article DOI: 10.1021/jm0311285 BindingDB Entry DOI: 10.7270/Q2BR8RNZ
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1 Show InChI InChI=1S/C33H41ClN6O2/c34-28-12-10-24(11-13-28)18-30(38-31(41)29-19-25-6-4-5-7-26(25)20-36-29)32(42)39-16-14-33(15-17-39,21-40-23-35-22-37-40)27-8-2-1-3-9-27/h4-7,10-13,22-23,27,29-30,36H,1-3,8-9,14-21H2,(H,38,41)/t29?,30-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity towards Melanocortin 4 receptor using [125I]NDP-MSH				J Med Chem 47: 4613-26 (2004) Article DOI: 10.1021/jm0311285 BindingDB Entry DOI: 10.7270/Q2BR8RNZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50207820 (CHEMBL3985384) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(OC(F)(F)F)cc2)s1 Show InChI InChI=1S/C12H10F3NO3S3/c13-12(14,15)19-9-3-1-8(2-4-9)7-20-10-5-6-11(21-10)22(16,17)18/h1-6H,7H2,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50207818 (CHEMBL3956725) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(cc2)C(F)(F)F)s1 Show InChI InChI=1S/C12H10F3NO2S3/c13-12(14,15)9-3-1-8(2-4-9)7-19-10-5-6-11(20-10)21(16,17)18/h1-6H,7H2,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 9 preincubated for 10 mins prior to testing by stopped-flow CO2 hyd...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50207818 (CHEMBL3956725) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(cc2)C(F)(F)F)s1 Show InChI InChI=1S/C12H10F3NO2S3/c13-12(14,15)9-3-1-8(2-4-9)7-19-10-5-6-11(20-10)21(16,17)18/h1-6H,7H2,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50207820 (CHEMBL3985384) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(OC(F)(F)F)cc2)s1 Show InChI InChI=1S/C12H10F3NO3S3/c13-12(14,15)19-9-3-1-8(2-4-9)7-20-10-5-6-11(21-10)22(16,17)18/h1-6H,7H2,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 9 preincubated for 10 mins prior to testing by stopped-flow CO2 hyd...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492876 (CHEMBL2414076) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C14H8F3N5O2S2/c15-14(16,17)10-5-9(2-1-8(10)6-18)22-7-11(20-21-22)12-3-4-13(25-12)26(19,23)24/h1-5,7H,(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492884 (CHEMBL2414068) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1cccc2ccccc12 Show InChI InChI=1S/C16H12N4O2S2/c17-24(21,22)16-9-8-15(23-16)13-10-20(19-18-13)14-7-3-5-11-4-1-2-6-12(11)14/h1-10H,(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492882 (CHEMBL2414075) Show SMILES CS(=O)(=O)c1ccc(c(F)c1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H11FN4O4S3/c1-24(19,20)8-2-3-11(9(14)6-8)18-7-10(16-17-18)12-4-5-13(23-12)25(15,21)22/h2-7H,1H3,(H2,15,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492870 (CHEMBL2414073) Show SMILES COc1ccc(cc1Cl)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H11ClN4O3S2/c1-21-11-3-2-8(6-9(11)14)18-7-10(16-17-18)12-4-5-13(22-12)23(15,19)20/h2-7H,1H3,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492877 (CHEMBL2414074) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(I)cc1 Show InChI InChI=1S/C12H9IN4O2S2/c13-8-1-3-9(4-2-8)17-7-10(15-16-17)11-5-6-12(20-11)21(14,18)19/h1-7H,(H2,14,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492872 (CHEMBL2413089) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H9F3N4O2S2/c14-13(15,16)8-1-3-9(4-2-8)20-7-10(18-19-20)11-5-6-12(23-11)24(17,21)22/h1-7H,(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50207736 (CHEMBL3947437) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(Cl)cc2)s1 Show InChI InChI=1S/C11H10ClNO2S3/c12-9-3-1-8(2-4-9)7-16-10-5-6-11(17-10)18(13,14)15/h1-6H,7H2,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492874 (CHEMBL2414066) Show SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C16H18N4O2S2/c1-16(2,3)11-4-6-12(7-5-11)20-10-13(18-19-20)14-8-9-15(23-14)24(17,21)22/h4-10H,1-3H3,(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492880 (CHEMBL2414072) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C12H8ClFN4O2S2/c13-8-5-7(1-2-9(8)14)18-6-10(16-17-18)11-3-4-12(21-11)22(15,19)20/h1-6H,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492878 (CHEMBL2414071) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C12H8Cl2N4O2S2/c13-8-2-1-7(5-9(8)14)18-6-10(16-17-18)11-3-4-12(21-11)22(15,19)20/h1-6H,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50492882 (CHEMBL2414075) Show SMILES CS(=O)(=O)c1ccc(c(F)c1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H11FN4O4S3/c1-24(19,20)8-2-3-11(9(14)6-8)18-7-10(16-17-18)12-4-5-13(23-12)25(15,21)22/h2-7H,1H3,(H2,15,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492883 (CHEMBL2414065) Show SMILES Cc1ccc(cc1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H12N4O2S2/c1-9-2-4-10(5-3-9)17-8-11(15-16-17)12-6-7-13(20-12)21(14,18)19/h2-8H,1H3,(H2,14,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50207818 (CHEMBL3956725) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(cc2)C(F)(F)F)s1 Show InChI InChI=1S/C12H10F3NO2S3/c13-12(14,15)9-3-1-8(2-4-9)7-19-10-5-6-11(20-10)21(16,17)18/h1-6H,7H2,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492881 (CHEMBL2414064) Show SMILES Cc1cccc(c1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H12N4O2S2/c1-9-3-2-4-10(7-9)17-8-11(15-16-17)12-5-6-13(20-12)21(14,18)19/h2-8H,1H3,(H2,14,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50207737 (CHEMBL3928543) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(F)cc2)s1 Show InChI InChI=1S/C11H10FNO2S3/c12-9-3-1-8(2-4-9)7-16-10-5-6-11(17-10)18(13,14)15/h1-6H,7H2,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492879 (CHEMBL2414070) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1cccc(c1)C#N Show InChI InChI=1S/C13H9N5O2S2/c14-7-9-2-1-3-10(6-9)18-8-11(16-17-18)12-4-5-13(21-12)22(15,19)20/h1-6,8H,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane CA12 catalytic domain after 6 hrs by stopped-flow CO2 hydration method				J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271176 (CHEMBL4130085) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=NN(C(O1)c1ccccc1[N+]([O-])=O)C(C)=O |t:14| Show InChI InChI=1S/C18H16N4O7S/c1-11(23)20-30(27,28)14-9-7-13(8-10-14)17-19-21(12(2)24)18(29-17)15-5-3-4-6-16(15)22(25)26/h3-10,18H,1-2H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50207820 (CHEMBL3985384) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(OC(F)(F)F)cc2)s1 Show InChI InChI=1S/C12H10F3NO3S3/c13-12(14,15)19-9-3-1-8(2-4-9)7-20-10-5-6-11(21-10)22(16,17)18/h1-6H,7H2,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271193 (CHEMBL4129969) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=NN(C(O1)c1ccc(C)cc1)C(C)=O |t:14| Show InChI InChI=1S/C19H19N3O5S/c1-12-4-6-16(7-5-12)19-22(14(3)24)20-18(27-19)15-8-10-17(11-9-15)28(25,26)21-13(2)23/h4-11,19H,1-3H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50207736 (CHEMBL3947437) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(Cl)cc2)s1 Show InChI InChI=1S/C11H10ClNO2S3/c12-9-3-1-8(2-4-9)7-16-10-5-6-11(17-10)18(13,14)15/h1-6H,7H2,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50207844 (CHEMBL3912159) Show SMILES NS(=O)(=O)c1ccc(SCc2ccccc2)s1 Show InChI InChI=1S/C11H11NO2S3/c12-17(13,14)11-7-6-10(16-11)15-8-9-4-2-1-3-5-9/h1-7H,8H2,(H2,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 9 preincubated for 10 mins prior to testing by stopped-flow CO2 hyd...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50492877 (CHEMBL2414074) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(I)cc1 Show InChI InChI=1S/C12H9IN4O2S2/c13-8-1-3-9(4-2-8)17-7-10(15-16-17)11-5-6-12(20-11)21(14,18)19/h1-7H,(H2,14,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50207843 (CHEMBL3956141) Show SMILES COc1ccc(CSc2ccc(s2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C12H13NO3S3/c1-16-10-4-2-9(3-5-10)8-17-11-6-7-12(18-11)19(13,14)15/h2-7H,8H2,1H3,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Institute of Organic Synthesis Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase-12 assessed as reduction in CO2 hydration preincubated for 10 mins measured for 5 to 10 secs by st...				Bioorg Med Chem 25: 3583-3589 (2017) Article DOI: 10.1016/j.bmc.2017.04.007 BindingDB Entry DOI: 10.7270/Q2G73GWZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50207815 (CHEMBL3977311) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc3ccccc3c2)s1 Show InChI InChI=1S/C15H13NO2S3/c16-21(17,18)15-8-7-14(20-15)19-10-11-5-6-12-3-1-2-4-13(12)9-11/h1-9H,10H2,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50492879 (CHEMBL2414070) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1cccc(c1)C#N Show InChI InChI=1S/C13H9N5O2S2/c14-7-9-2-1-3-10(6-9)18-8-11(16-17-18)12-4-5-13(21-12)22(15,19)20/h1-6,8H,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50207843 (CHEMBL3956141) Show SMILES COc1ccc(CSc2ccc(s2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C12H13NO3S3/c1-16-10-4-2-9(3-5-10)8-17-11-6-7-12(18-11)19(13,14)15/h2-7H,8H2,1H3,(H2,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 9 preincubated for 10 mins prior to testing by stopped-flow CO2 hyd...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492875 (CHEMBL2414077) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccccc1 Show InChI InChI=1S/C12H10N4O2S2/c13-20(17,18)12-7-6-11(19-12)10-8-16(15-14-10)9-4-2-1-3-5-9/h1-8H,(H2,13,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271194 (CHEMBL4127617) Show SMILES COc1ccccc1C1OC(=NN1C(C)=O)c1ccc(cc1)S(=O)(=O)NC(C)=O |c:11| Show InChI InChI=1S/C19H19N3O6S/c1-12(23)21-29(25,26)15-10-8-14(9-11-15)18-20-22(13(2)24)19(28-18)16-6-4-5-7-17(16)27-3/h4-11,19H,1-3H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50492881 (CHEMBL2414064) Show SMILES Cc1cccc(c1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H12N4O2S2/c1-9-3-2-4-10(7-9)17-8-11(15-16-17)12-5-6-13(20-12)21(14,18)19/h2-8H,1H3,(H2,14,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271182 (CHEMBL4129897) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=NN(C(O1)c1ccccc1C)C(C)=O |t:14| Show InChI InChI=1S/C19H19N3O5S/c1-12-6-4-5-7-17(12)19-22(14(3)24)20-18(27-19)15-8-10-16(11-9-15)28(25,26)21-13(2)23/h4-11,19H,1-3H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50492873 (CHEMBL2414067) Show SMILES COc1ccc(cc1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H12N4O3S2/c1-20-10-4-2-9(3-5-10)17-8-11(15-16-17)12-6-7-13(21-12)22(14,18)19/h2-8H,1H3,(H2,14,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50492873 (CHEMBL2414067) Show SMILES COc1ccc(cc1)-n1cc(nn1)-c1ccc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H12N4O3S2/c1-20-10-4-2-9(3-5-10)17-8-11(15-16-17)12-6-7-13(21-12)22(14,18)19/h2-8H,1H3,(H2,14,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50492880 (CHEMBL2414072) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C12H8ClFN4O2S2/c13-8-5-7(1-2-9(8)14)18-6-10(16-17-18)11-3-4-12(21-11)22(15,19)20/h1-6H,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271198 (CHEMBL4126627) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=NN(C(O1)c1cccc(c1)[N+]([O-])=O)C(C)=O |t:14| Show InChI InChI=1S/C18H16N4O7S/c1-11(23)20-30(27,28)16-8-6-13(7-9-16)17-19-21(12(2)24)18(29-17)14-4-3-5-15(10-14)22(25)26/h3-10,18H,1-2H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271196 (CHEMBL4126396) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=NN(C(O1)c1ccc(F)cc1)C(C)=O |t:14| Show InChI InChI=1S/C18H16FN3O5S/c1-11(23)21-28(25,26)16-9-5-13(6-10-16)17-20-22(12(2)24)18(27-17)14-3-7-15(19)8-4-14/h3-10,18H,1-2H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50271202 (CHEMBL4126466) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=NN(C(O1)c1ccc(F)cc1F)C(C)=O |t:14| Show InChI InChI=1S/C18H15F2N3O5S/c1-10(24)22-29(26,27)14-6-3-12(4-7-14)17-21-23(11(2)25)18(28-17)15-8-5-13(19)9-16(15)20/h3-9,18H,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 12 assessed as reduction in CO2 hydration pretreated for 15 mins followed by CO2 addition measured...				ACS Med Chem Lett 8: 792-796 (2017) Article DOI: 10.1021/acsmedchemlett.7b00205 BindingDB Entry DOI: 10.7270/Q2FN18PV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50207736 (CHEMBL3947437) Show SMILES NS(=O)(=O)c1ccc(SCc2ccc(Cl)cc2)s1 Show InChI InChI=1S/C11H10ClNO2S3/c12-9-3-1-8(2-4-9)7-16-10-5-6-11(17-10)18(13,14)15/h1-6H,7H2,(H2,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Riga Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 9 preincubated for 10 mins prior to testing by stopped-flow CO2 hyd...				Bioorg Med Chem 25: 857-863 (2017) Article DOI: 10.1016/j.bmc.2016.11.045 BindingDB Entry DOI: 10.7270/Q2M61N7N
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50426698 (CHEMBL2326518) Show SMILES CCN(CC)Cc1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1 |c:20| Show InChI InChI=1S/C15H18N4O3S/c1-3-18(4-2)10-13-11-19(17-16-13)14-5-6-15-12(9-14)7-8-23(20,21)22-15/h5-9,11H,3-4,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane CA12 catalytic domain after 6 hrs by stopped-flow CO2 hydration method				J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50492875 (CHEMBL2414077) Show SMILES NS(=O)(=O)c1ccc(s1)-c1cn(nn1)-c1ccccc1 Show InChI InChI=1S/C12H10N4O2S2/c13-20(17,18)12-7-6-11(19-12)10-8-16(15-14-10)9-4-2-1-3-5-9/h1-8H,(H2,13,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 21: 5130-8 (2013) Article DOI: 10.1016/j.bmc.2013.06.041 BindingDB Entry DOI: 10.7270/Q2417108
					More data for this Ligand-Target Pair

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