Compile Data Set for Download or QSAR

Found 1253 hits with Last Name = 'terreni' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus (rat))	BDBM50308250 ((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...) Show SMILES CCOC[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2NO/c1-2-18-7-11-10-6-17-8-14(10,11)9-3-4-12(15)13(16)5-9/h3-5,10-11,17H,2,6-8H2,1H3/t10-,11-,14+/m1/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [N-methyl-3H]nisoxetine from rat hippocampus NET by filtration binding assay				J Med Chem 53: 2534-51 (2010) Article DOI: 10.1021/jm901818u BindingDB Entry DOI: 10.7270/Q2ST7PX2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002630 (CHEMBL377174) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1ccc(C)cc1 |c:21| Show InChI InChI=1S/C25H30N2O3/c1-19-6-8-20(9-7-19)22-12-15-27(25(22)28)21-10-11-23(29-2)24(18-21)30-17-16-26-13-4-3-5-14-26/h6-12,18H,3-5,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476485 (CHEMBL234739) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(F)cc(c2C1=O)C(F)(F)F Show InChI InChI=1S/C24H26F4N2O3/c1-15-5-7-29(8-6-15)9-10-33-21-13-18(3-4-20(21)32-2)30-14-16-11-17(25)12-19(24(26,27)28)22(16)23(30)31/h3-4,11-13,15H,5-10,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50312271 ((1S,5R)-3-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-y...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2C[C@@H]3C[C@@]3(C2)c2ccc(cc2)C(F)(F)F)n1C |r| Show InChI InChI=1S/C22H24F3N5OS/c1-14-18(31-13-26-14)19-27-28-20(29(19)2)32-9-3-8-30-11-17-10-21(17,12-30)15-4-6-16(7-5-15)22(23,24)25/h4-7,13,17H,3,8-12H2,1-2H3/t17-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at dopamine D3 receptor by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 5491-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.073 BindingDB Entry DOI: 10.7270/Q2R78GFH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002642 (CHEMBL213987) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1ccc(Cl)c(Cl)c1 |c:21| Show InChI InChI=1S/C24H26Cl2N2O3/c1-30-22-8-6-18(16-23(22)31-14-13-27-10-3-2-4-11-27)28-12-9-19(24(28)29)17-5-7-20(25)21(26)15-17/h5-9,15-16H,2-4,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002616 (CHEMBL213839) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1cccc(F)c1 |c:21| Show InChI InChI=1S/C24H27FN2O3/c1-29-22-9-8-20(17-23(22)30-15-14-26-11-3-2-4-12-26)27-13-10-21(24(27)28)18-6-5-7-19(25)16-18/h5-10,16-17H,2-4,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50331549 (CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1 Show InChI InChI=1S/C18H21F3N4O/c19-18(20,21)15-4-6-23(7-5-15)8-9-24-10-11-25(17(24)26)16-3-1-2-14(12-16)13-22/h1-3,12,15H,4-11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to dopamine D3 receptor in rat native tissue by filtration binding assay				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50331549 (CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1 Show InChI InChI=1S/C18H21F3N4O/c19-18(20,21)15-4-6-23(7-5-15)8-9-24-10-11-25(17(24)26)16-3-1-2-14(12-16)13-22/h1-3,12,15H,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to human dopamine D3 receptor by filtration binding assay				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411716 (CHEMBL429132) Show SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(C)(C)C)n1C Show InChI InChI=1S/C31H36N6OS/c1-20-10-11-23-24(8-6-9-25(23)32-20)28-34-35-30(36(28)5)39-17-7-14-37-15-12-21-18-26-27(19-22(21)13-16-37)38-29(33-26)31(2,3)4/h6,8-11,18-19H,7,12-17H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476478 (CHEMBL234109) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(Br)c2C1=O Show InChI InChI=1S/C23H27BrN2O3/c1-16-8-10-25(11-9-16)12-13-29-21-14-18(6-7-20(21)28-2)26-15-17-4-3-5-19(24)22(17)23(26)27/h3-7,14,16H,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (MOUSE)	BDBM50308250 ((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...) Show SMILES CCOC[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2NO/c1-2-18-7-11-10-6-17-8-14(10,11)9-3-4-12(15)13(16)5-9/h3-5,10-11,17H,2,6-8H2,1H3/t10-,11-,14+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from mouse cortex SERT by filtration binding assay				J Med Chem 53: 2534-51 (2010) Article DOI: 10.1021/jm901818u BindingDB Entry DOI: 10.7270/Q2ST7PX2
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411713 (CHEMBL255620) Show SMILES CN(C)c1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2o1 Show InChI InChI=1S/C29H33N7OS/c1-19-9-10-22-23(7-5-8-24(22)30-19)27-32-33-29(35(27)4)38-16-6-13-36-14-11-20-17-25-26(18-21(20)12-15-36)37-28(31-25)34(2)3/h5,7-10,17-18H,6,11-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476492 (CHEMBL234533) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2ccc(Cl)c(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-7-9-26(10-8-15)11-12-30-20-13-17(4-6-19(20)29-2)27-14-16-3-5-18(24)22(25)21(16)23(27)28/h3-6,13,15H,7-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414436 (CHEMBL560574) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(I)c2)CC1 Show InChI InChI=1S/C17H21F3IN3O/c18-17(19,20)13-4-6-22(7-5-13)8-9-23-10-11-24(16(23)25)15-3-1-2-14(21)12-15/h1-3,12-13H,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50331549 (CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1 Show InChI InChI=1S/C18H21F3N4O/c19-18(20,21)15-4-6-23(7-5-15)8-9-24-10-11-25(17(24)26)16-3-1-2-14(12-16)13-22/h1-3,12,15H,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50416717 (CHEMBL1224699) Show SMILES COc1cc(ccc1NS(=O)(=O)c1ccc(cc1)C(C)C)[C@@]12C[C@@H]1CNC2 |r| Show InChI InChI=1S/C21H26N2O3S/c1-14(2)15-4-7-18(8-5-15)27(24,25)23-19-9-6-16(10-20(19)26-3)21-11-17(21)12-22-13-21/h4-10,14,17,22-23H,11-13H2,1-3H3/t17-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at dopamine D3 receptor by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 5491-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.073 BindingDB Entry DOI: 10.7270/Q2R78GFH
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414406 (CHEMBL561512) Show SMILES Clc1cc(Cl)cc(c1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C19H19Cl2N3O/c20-16-9-17(21)11-18(10-16)24-8-7-23(19(24)25)6-5-22-12-14-3-1-2-4-15(14)13-22/h1-4,9-11H,5-8,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414435 (CHEMBL569846) Show SMILES Oc1cccc(c1)N1CCN(CCN2CCC(CC2)C(F)(F)F)C1=O Show InChI InChI=1S/C17H22F3N3O2/c18-17(19,20)13-4-6-21(7-5-13)8-9-22-10-11-23(16(22)25)14-2-1-3-15(24)12-14/h1-3,12-13,24H,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476481 (CHEMBL395059) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1C(C)c2cccc(Cl)c2C1=O Show InChI InChI=1S/C24H29ClN2O3/c1-16-9-11-26(12-10-16)13-14-30-22-15-18(7-8-21(22)29-3)27-17(2)19-5-4-6-20(25)23(19)24(27)28/h4-8,15-17H,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002678 (CHEMBL210053) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1ccc(Br)cc1 |c:21| Show InChI InChI=1S/C24H27BrN2O3/c1-29-22-10-9-20(17-23(22)30-16-15-26-12-3-2-4-13-26)27-14-11-21(24(27)28)18-5-7-19(25)8-6-18/h5-11,17H,2-4,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476486 (CHEMBL395298) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)c(C)c(Cl)c2C1=O Show InChI InChI=1S/C24H28Cl2N2O3/c1-15-6-8-27(9-7-15)10-11-31-21-13-18(4-5-20(21)30-3)28-14-17-12-19(25)16(2)23(26)22(17)24(28)29/h4-5,12-13,15H,6-11,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (MOUSE)	BDBM50322698 (rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...) Show SMILES COC[C@]12C[C@]1(CCNC2)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2NO/c1-18-9-13-7-14(13,4-5-17-8-13)10-2-3-11(15)12(16)6-10/h2-3,6,17H,4-5,7-9H2,1H3/t13-,14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET in mouse brain				J Med Chem 53: 4989-5001 (2010) Article DOI: 10.1021/jm100481d BindingDB Entry DOI: 10.7270/Q20V8DR3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (MOUSE)	BDBM50322698 (rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...) Show SMILES COC[C@]12C[C@]1(CCNC2)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2NO/c1-18-9-13-7-14(13,4-5-17-8-13)10-2-3-11(15)12(16)6-10/h2-3,6,17H,4-5,7-9H2,1H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]-citalopram from SERT in mouse cortex after 2 hrs by liquid scintillation counting				J Med Chem 53: 4989-5001 (2010) Article DOI: 10.1021/jm100481d BindingDB Entry DOI: 10.7270/Q20V8DR3
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414437 (CHEMBL562624) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C17H21ClF3N3O/c18-14-2-1-3-15(12-14)24-11-10-23(16(24)25)9-8-22-6-4-13(5-7-22)17(19,20)21/h1-3,12-13H,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414413 (CHEMBL556272) Show SMILES Fc1cc(Cl)cc(c1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C19H19ClFN3O/c20-16-9-17(21)11-18(10-16)24-8-7-23(19(24)25)6-5-22-12-14-3-1-2-4-15(14)13-22/h1-4,9-11H,5-8,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414409 (CHEMBL565017) Show SMILES FC(F)(F)Oc1cccc(c1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)28-18-7-3-6-17(12-18)26-11-10-25(19(26)27)9-8-24-13-15-4-1-2-5-16(15)14-24/h1-7,12H,8-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411678 (CHEMBL273199) Show SMILES Cc1cc(-c2ccc3CCN(CCCSc4nnc(-c5cccc6cnc(C)cc56)n4C)CCc3c2)n(C)n1 Show InChI InChI=1S/C31H35N7S/c1-21-17-28-26(20-32-21)7-5-8-27(28)30-33-34-31(36(30)3)39-16-6-13-38-14-11-23-9-10-25(19-24(23)12-15-38)29-18-22(2)35-37(29)4/h5,7-10,17-20H,6,11-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002663 (CHEMBL386332) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1CC=C(C1=O)c1ccc(C)cc1 |c:22| Show InChI InChI=1S/C26H32N2O3/c1-19-4-6-21(7-5-19)23-12-15-28(26(23)29)22-8-9-24(30-3)25(18-22)31-17-16-27-13-10-20(2)11-14-27/h4-9,12,18,20H,10-11,13-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476467 (CHEMBL396747) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(Cl)c2C1=O Show InChI InChI=1S/C23H27ClN2O3/c1-16-8-10-25(11-9-16)12-13-29-21-14-18(6-7-20(21)28-2)26-15-17-4-3-5-19(24)22(17)23(26)27/h3-7,14,16H,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476474 (CHEMBL234532) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-5-7-26(8-6-15)9-10-30-21-13-18(3-4-20(21)29-2)27-14-16-11-17(24)12-19(25)22(16)23(27)28/h3-4,11-13,15H,5-10,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476462 (CHEMBL396748) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(c2C1=O)C(F)(F)F Show InChI InChI=1S/C24H27F3N2O3/c1-16-8-10-28(11-9-16)12-13-32-21-14-18(6-7-20(21)31-2)29-15-17-4-3-5-19(24(25,26)27)22(17)23(29)30/h3-7,14,16H,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476504 (CHEMBL388882) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2sc3ccccc3c2C1=O Show InChI InChI=1S/C25H28N2O3S/c1-17-9-11-26(12-10-17)13-14-30-21-15-18(7-8-20(21)29-2)27-16-23-24(25(27)28)19-5-3-4-6-22(19)31-23/h3-8,15,17H,9-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476479 (CHEMBL234494) Show SMILES COc1ccc(cc1OCCN1CCC(C)(C)CC1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C24H28Cl2N2O3/c1-24(2)6-8-27(9-7-24)10-11-31-21-14-18(4-5-20(21)30-3)28-15-16-12-17(25)13-19(26)22(16)23(28)29/h4-5,12-14H,6-11,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476488 (CHEMBL234531) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c(Cl)cc(F)c2F Show InChI InChI=1S/C23H25ClF2N2O3/c1-14-5-7-27(8-6-14)9-10-31-20-11-15(3-4-19(20)30-2)28-13-16-21(23(28)29)17(24)12-18(25)22(16)26/h3-4,11-12,14H,5-10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476494 (CHEMBL234948) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1Cc2c(C1=O)c1cc(Cl)ccc1n2C Show InChI InChI=1S/C25H28ClN3O3/c1-27-20-8-6-17(26)14-19(20)24-21(27)16-29(25(24)30)18-7-9-22(31-2)23(15-18)32-13-12-28-10-4-3-5-11-28/h6-9,14-15H,3-5,10-13,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476480 (CHEMBL234006) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(C)c2C1=O Show InChI InChI=1S/C24H30N2O3/c1-17-9-11-25(12-10-17)13-14-29-22-15-20(7-8-21(22)28-3)26-16-19-6-4-5-18(2)23(19)24(26)27/h4-8,15,17H,9-14,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476503 (CHEMBL395098) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c1cccc(F)c1n2C Show InChI InChI=1S/C26H30FN3O3/c1-17-9-11-29(12-10-17)13-14-33-23-15-18(7-8-22(23)32-3)30-16-21-24(26(30)31)19-5-4-6-20(27)25(19)28(21)2/h4-8,15,17H,9-14,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476499 (CHEMBL232254) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c1cc(F)ccc1n2C Show InChI InChI=1S/C26H30FN3O3/c1-17-8-10-29(11-9-17)12-13-33-24-15-19(5-7-23(24)32-3)30-16-22-25(26(30)31)20-14-18(27)4-6-21(20)28(22)2/h4-7,14-15,17H,8-13,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476473 (CHEMBL234738) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)c(Cl)c(C)c2C1=O Show InChI InChI=1S/C24H28Cl2N2O3/c1-15-6-8-27(9-7-15)10-11-31-21-13-18(4-5-20(21)30-3)28-14-17-12-19(25)23(26)16(2)22(17)24(28)29/h4-5,12-13,15H,6-11,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002664 (CHEMBL212270) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1cccc(Cl)c1 |c:21| Show InChI InChI=1S/C24H27ClN2O3/c1-29-22-9-8-20(17-23(22)30-15-14-26-11-3-2-4-12-26)27-13-10-21(24(27)28)18-6-5-7-19(25)16-18/h5-10,16-17H,2-4,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476463 (CHEMBL234492) Show SMILES COc1ccc(cc1OCCN1CCCC(C)C1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-4-3-7-26(13-15)8-9-30-21-12-18(5-6-20(21)29-2)27-14-16-10-17(24)11-19(25)22(16)23(27)28/h5-6,10-12,15H,3-4,7-9,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476464 (CHEMBL395072) Show SMILES COc1ccc(cc1OCCN1CCCCCC1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-29-20-7-6-18(14-21(20)30-11-10-26-8-4-2-3-5-9-26)27-15-16-12-17(24)13-19(25)22(16)23(27)28/h6-7,12-14H,2-5,8-11,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414412 (CHEMBL559856) Show SMILES O=C1N(CCN2Cc3ccccc3C2)CCN1c1cccc(c1)C#N Show InChI InChI=1S/C20H20N4O/c21-13-16-4-3-7-19(12-16)24-11-10-23(20(24)25)9-8-22-14-17-5-1-2-6-18(17)15-22/h1-7,12H,8-11,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414404 (CHEMBL559029) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C20H20F3N3O/c21-20(22,23)17-6-3-7-18(12-17)26-11-10-25(19(26)27)9-8-24-13-15-4-1-2-5-16(15)14-24/h1-7,12H,8-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414403 (CHEMBL560177) Show SMILES Clc1cccc(c1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C19H20ClN3O/c20-17-6-3-7-18(12-17)23-11-10-22(19(23)24)9-8-21-13-15-4-1-2-5-16(15)14-21/h1-7,12H,8-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411672 (CHEMBL256477) Show SMILES CCc1nn(C)c2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc12 Show InChI InChI=1S/C30H35N7S/c1-5-26-25-18-21-12-15-37(16-13-22(21)19-28(25)36(4)34-26)14-7-17-38-30-33-32-29(35(30)3)24-8-6-9-27-23(24)11-10-20(2)31-27/h6,8-11,18-19H,5,7,12-17H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411669 (CHEMBL271631) Show SMILES CCc1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2s1 Show InChI InChI=1S/C29H32N6S2/c1-4-27-31-25-17-20-11-14-35(15-12-21(20)18-26(25)37-27)13-6-16-36-29-33-32-28(34(29)3)23-7-5-8-24-22(23)10-9-19(2)30-24/h5,7-10,17-18H,4,6,11-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50416716 (CHEMBL1224698) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)[C@@]12C[C@@H]1CN(CC=C)C2 |r| Show InChI InChI=1S/C23H28N2O2S/c1-4-13-25-15-20-14-23(20,16-25)19-7-9-21(10-8-19)24-28(26,27)22-11-5-18(6-12-22)17(2)3/h4-12,17,20,24H,1,13-16H2,2-3H3/t20-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at dopamine D3 receptor by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 5491-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.073 BindingDB Entry DOI: 10.7270/Q2R78GFH
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414434 (CHEMBL551914) Show SMILES CC1CCN(CCN2CCN(C2=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C17H24ClN3O/c1-14-5-7-19(8-6-14)9-10-20-11-12-21(17(20)22)16-4-2-3-15(18)13-16/h2-4,13-14H,5-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM50322698 (rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...) Show SMILES COC[C@]12C[C@]1(CCNC2)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2NO/c1-18-9-13-7-14(13,4-5-17-8-13)10-2-3-11(15)12(16)6-10/h2-3,6,17H,4-5,7-9H2,1H3/t13-,14-/m1/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET in rat hippocampus after 2 hrs by liquid scintillation counting				J Med Chem 53: 4989-5001 (2010) Article DOI: 10.1021/jm100481d BindingDB Entry DOI: 10.7270/Q20V8DR3
					More data for this Ligand-Target Pair

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