Compile Data Set for Download or QSAR

Found 94 hits with Last Name = 'theaker' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50296345 ((1R,2R,4S,5R,7S)-7-(2-hydroxy-2,2-di-thiophen-2-yl...) Show SMILES C[N+]1(C)[C@@H]2C[C@H](C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 |TLB:11:5:1:8.10| Show InChI InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13-,16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0316	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50296345 ((1R,2R,4S,5R,7S)-7-(2-hydroxy-2,2-di-thiophen-2-yl...) Show SMILES C[N+]1(C)[C@@H]2C[C@H](C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 |TLB:11:5:1:8.10| Show InChI InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13-,16-,17+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0316	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50296345 ((1R,2R,4S,5R,7S)-7-(2-hydroxy-2,2-di-thiophen-2-yl...) Show SMILES C[N+]1(C)[C@@H]2C[C@H](C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 |TLB:11:5:1:8.10| Show InChI InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13-,16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0398	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50296345 ((1R,2R,4S,5R,7S)-7-(2-hydroxy-2,2-di-thiophen-2-yl...) Show SMILES C[N+]1(C)[C@@H]2C[C@H](C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 |TLB:11:5:1:8.10| Show InChI InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13-,16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0501	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50296345 ((1R,2R,4S,5R,7S)-7-(2-hydroxy-2,2-di-thiophen-2-yl...) Show SMILES C[N+]1(C)[C@@H]2C[C@H](C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 |TLB:11:5:1:8.10| Show InChI InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13-,16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50296331 ((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...) Show SMILES OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1 |r,wD:5.4,(-4.87,-33.87,;-5.96,-34.96,;-4.62,-35.72,;-4.61,-37.26,;-3.29,-34.95,;-1.95,-35.72,;-1.95,-37.26,;-.62,-38.02,;-.64,-39.56,;.69,-40.34,;2.03,-39.58,;3.36,-40.37,;4.7,-39.61,;6.02,-40.39,;7.36,-39.64,;7.37,-38.1,;6.04,-37.31,;4.7,-38.07,;.71,-37.26,;.71,-35.72,;-.62,-34.94,;-.2,-36.18,;-1.25,-36.53,;-5.96,-33.42,;-7.21,-32.51,;-6.74,-31.04,;-5.2,-31.04,;-4.72,-32.5,;-7.29,-35.73,;-8.7,-35.11,;-9.73,-36.25,;-8.96,-37.59,;-7.45,-37.26,)| Show InChI InChI=1S/C26H30NO4S2/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2/q+1/t20?,22-,27?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50296331 ((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...) Show SMILES OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1 |r,wD:5.4,(-4.87,-33.87,;-5.96,-34.96,;-4.62,-35.72,;-4.61,-37.26,;-3.29,-34.95,;-1.95,-35.72,;-1.95,-37.26,;-.62,-38.02,;-.64,-39.56,;.69,-40.34,;2.03,-39.58,;3.36,-40.37,;4.7,-39.61,;6.02,-40.39,;7.36,-39.64,;7.37,-38.1,;6.04,-37.31,;4.7,-38.07,;.71,-37.26,;.71,-35.72,;-.62,-34.94,;-.2,-36.18,;-1.25,-36.53,;-5.96,-33.42,;-7.21,-32.51,;-6.74,-31.04,;-5.2,-31.04,;-4.72,-32.5,;-7.29,-35.73,;-8.7,-35.11,;-9.73,-36.25,;-8.96,-37.59,;-7.45,-37.26,)| Show InChI InChI=1S/C26H30NO4S2/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2/q+1/t20?,22-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	0.126	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50296331 ((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...) Show SMILES OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1 |r,wD:5.4,(-4.87,-33.87,;-5.96,-34.96,;-4.62,-35.72,;-4.61,-37.26,;-3.29,-34.95,;-1.95,-35.72,;-1.95,-37.26,;-.62,-38.02,;-.64,-39.56,;.69,-40.34,;2.03,-39.58,;3.36,-40.37,;4.7,-39.61,;6.02,-40.39,;7.36,-39.64,;7.37,-38.1,;6.04,-37.31,;4.7,-38.07,;.71,-37.26,;.71,-35.72,;-.62,-34.94,;-.2,-36.18,;-1.25,-36.53,;-5.96,-33.42,;-7.21,-32.51,;-6.74,-31.04,;-5.2,-31.04,;-4.72,-32.5,;-7.29,-35.73,;-8.7,-35.11,;-9.73,-36.25,;-8.96,-37.59,;-7.45,-37.26,)| Show InChI InChI=1S/C26H30NO4S2/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2/q+1/t20?,22-,27?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.126	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50417445 (AHR-504 | CUVPOSA | GLYCOPYRROLATE) Show SMILES C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.126	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50296331 ((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...) Show SMILES OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1 |r,wD:5.4,(-4.87,-33.87,;-5.96,-34.96,;-4.62,-35.72,;-4.61,-37.26,;-3.29,-34.95,;-1.95,-35.72,;-1.95,-37.26,;-.62,-38.02,;-.64,-39.56,;.69,-40.34,;2.03,-39.58,;3.36,-40.37,;4.7,-39.61,;6.02,-40.39,;7.36,-39.64,;7.37,-38.1,;6.04,-37.31,;4.7,-38.07,;.71,-37.26,;.71,-35.72,;-.62,-34.94,;-.2,-36.18,;-1.25,-36.53,;-5.96,-33.42,;-7.21,-32.51,;-6.74,-31.04,;-5.2,-31.04,;-4.72,-32.5,;-7.29,-35.73,;-8.7,-35.11,;-9.73,-36.25,;-8.96,-37.59,;-7.45,-37.26,)| Show InChI InChI=1S/C26H30NO4S2/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2/q+1/t20?,22-,27?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	0.158	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50417445 (AHR-504 | CUVPOSA | GLYCOPYRROLATE) Show SMILES C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.158	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50417445 (AHR-504 | CUVPOSA | GLYCOPYRROLATE) Show SMILES C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50296331 ((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...) Show SMILES OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1 |r,wD:5.4,(-4.87,-33.87,;-5.96,-34.96,;-4.62,-35.72,;-4.61,-37.26,;-3.29,-34.95,;-1.95,-35.72,;-1.95,-37.26,;-.62,-38.02,;-.64,-39.56,;.69,-40.34,;2.03,-39.58,;3.36,-40.37,;4.7,-39.61,;6.02,-40.39,;7.36,-39.64,;7.37,-38.1,;6.04,-37.31,;4.7,-38.07,;.71,-37.26,;.71,-35.72,;-.62,-34.94,;-.2,-36.18,;-1.25,-36.53,;-5.96,-33.42,;-7.21,-32.51,;-6.74,-31.04,;-5.2,-31.04,;-4.72,-32.5,;-7.29,-35.73,;-8.7,-35.11,;-9.73,-36.25,;-8.96,-37.59,;-7.45,-37.26,)| Show InChI InChI=1S/C26H30NO4S2/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2/q+1/t20?,22-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417445 (AHR-504 | CUVPOSA | GLYCOPYRROLATE) Show SMILES C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	0.251	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417445 (AHR-504 | CUVPOSA | GLYCOPYRROLATE) Show SMILES C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.501	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417438 (CHEMBL1289653) Show SMILES Cc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3cccc(Cl)c3)CC2)C1 Show InChI InChI=1S/C20H24ClN3O2S/c1-15-22-18(13-27-15)19(25)24-9-10-26-20(14-24)5-7-23(8-6-20)12-16-3-2-4-17(21)11-16/h2-4,11,13H,5-10,12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417438 (CHEMBL1289653) Show SMILES Cc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3cccc(Cl)c3)CC2)C1 Show InChI InChI=1S/C20H24ClN3O2S/c1-15-22-18(13-27-15)19(25)24-9-10-26-20(14-24)5-7-23(8-6-20)12-16-3-2-4-17(21)11-16/h2-4,11,13H,5-10,12,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417428 (CHEMBL1290184) Show SMILES Cc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C24H30N2O/c1-20-6-5-7-21(18-20)19-25-14-10-24(11-15-25)12-16-26(17-13-24)23(27)22-8-3-2-4-9-22/h2-9,18H,10-17,19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417450 (CHEMBL1289545) Show SMILES Cc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C20H24ClN3O2S/c1-15-22-18(13-27-15)19(25)24-10-11-26-20(14-24)6-8-23(9-7-20)12-16-2-4-17(21)5-3-16/h2-5,13H,6-12,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417457 (CHEMBL1289654) Show SMILES Cc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccccc3Cl)CC2)C1 Show InChI InChI=1S/C20H24ClN3O2S/c1-15-22-18(13-27-15)19(25)24-10-11-26-20(14-24)6-8-23(9-7-20)12-16-4-2-3-5-17(16)21/h2-5,13H,6-12,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417452 (CHEMBL1290183) Show SMILES Clc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C23H27ClN2O/c24-21-8-4-5-19(17-21)18-25-13-9-23(10-14-25)11-15-26(16-12-23)22(27)20-6-2-1-3-7-20/h1-8,17H,9-16,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417441 (CHEMBL1289866) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccccc3)CC2)C1 Show InChI InChI=1S/C22H29N3O2S/c1-17(2)20-23-19(15-28-20)21(26)25-12-13-27-22(16-25)8-10-24(11-9-22)14-18-6-4-3-5-7-18/h3-7,15,17H,8-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417459 (CHEMBL1289983) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3cccc(Cl)c3)CC2)C1 Show InChI InChI=1S/C22H28ClN3O2S/c1-16(2)20-24-19(14-29-20)21(27)26-10-11-28-22(15-26)6-8-25(9-7-22)13-17-4-3-5-18(23)12-17/h3-5,12,14,16H,6-11,13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417429 (CHEMBL1290294) Show SMILES O=C(N1CCC2(CCN(Cc3ccccc3)CC2)CC1)c1ccccc1 Show InChI InChI=1S/C23H28N2O/c26-22(21-9-5-2-6-10-21)25-17-13-23(14-18-25)11-15-24(16-12-23)19-20-7-3-1-4-8-20/h1-10H,11-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417457 (CHEMBL1289654) Show SMILES Cc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccccc3Cl)CC2)C1 Show InChI InChI=1S/C20H24ClN3O2S/c1-15-22-18(13-27-15)19(25)24-10-11-26-20(14-24)6-8-23(9-7-20)12-16-4-2-3-5-17(16)21/h2-5,13H,6-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417459 (CHEMBL1289983) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3cccc(Cl)c3)CC2)C1 Show InChI InChI=1S/C22H28ClN3O2S/c1-16(2)20-24-19(14-29-20)21(27)26-10-11-28-22(15-26)6-8-25(9-7-22)13-17-4-3-5-18(23)12-17/h3-5,12,14,16H,6-11,13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417450 (CHEMBL1289545) Show SMILES Cc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C20H24ClN3O2S/c1-15-22-18(13-27-15)19(25)24-10-11-26-20(14-24)6-8-23(9-7-20)12-16-2-4-17(21)5-3-16/h2-5,13H,6-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417439 (CHEMBL1289758) Show SMILES CCc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C21H26ClN3O2S/c1-2-19-23-18(14-28-19)20(26)25-11-12-27-21(15-25)7-9-24(10-8-21)13-16-3-5-17(22)6-4-16/h3-6,14H,2,7-13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417431 (CHEMBL1290410) Show SMILES O=C(N1CCC2(CCN(Cc3ccccc3)CC2)CC1)c1ccsc1 Show InChI InChI=1S/C21H26N2OS/c24-20(19-6-15-25-17-19)23-13-9-21(10-14-23)7-11-22(12-8-21)16-18-4-2-1-3-5-18/h1-6,15,17H,7-14,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417441 (CHEMBL1289866) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccccc3)CC2)C1 Show InChI InChI=1S/C22H29N3O2S/c1-17(2)20-23-19(15-28-20)21(26)25-12-13-27-22(16-25)8-10-24(11-9-22)14-18-6-4-3-5-7-18/h3-7,15,17H,8-14,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417458 (CHEMBL1289865) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C22H28ClN3O2S/c1-16(2)20-24-19(14-29-20)21(27)26-11-12-28-22(15-26)7-9-25(10-8-22)13-17-3-5-18(23)6-4-17/h3-6,14,16H,7-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417439 (CHEMBL1289758) Show SMILES CCc1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C21H26ClN3O2S/c1-2-19-23-18(14-28-19)20(26)25-11-12-27-21(15-25)7-9-24(10-8-21)13-16-3-5-17(22)6-4-16/h3-6,14H,2,7-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417442 (CHEMBL1289982) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccccc3Cl)CC2)C1 Show InChI InChI=1S/C22H28ClN3O2S/c1-16(2)20-24-19(14-29-20)21(27)26-11-12-28-22(15-26)7-9-25(10-8-22)13-17-5-3-4-6-18(17)23/h3-6,14,16H,7-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417434 (CHEMBL1289082) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2cccs2)cc1 Show InChI InChI=1S/C20H23ClN2O2S/c21-17-5-3-16(4-6-17)14-22-9-7-20(8-10-22)15-23(11-12-25-20)19(24)18-2-1-13-26-18/h1-6,13H,7-12,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417442 (CHEMBL1289982) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccccc3Cl)CC2)C1 Show InChI InChI=1S/C22H28ClN3O2S/c1-16(2)20-24-19(14-29-20)21(27)26-11-12-28-22(15-26)7-9-25(10-8-22)13-17-5-3-4-6-18(17)23/h3-6,14,16H,7-13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417447 (CHEMBL1289081) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2ccco2)cc1 Show InChI InChI=1S/C20H23ClN2O3/c21-17-5-3-16(4-6-17)14-22-9-7-20(8-10-22)15-23(11-13-26-20)19(24)18-2-1-12-25-18/h1-6,12H,7-11,13-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417433 (CHEMBL1290752) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2ccc3occc3c2)cc1 Show InChI InChI=1S/C24H25ClN2O3/c25-21-4-1-18(2-5-21)16-26-10-8-24(9-11-26)17-27(12-14-30-24)23(28)20-3-6-22-19(15-20)7-13-29-22/h1-7,13,15H,8-12,14,16-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417433 (CHEMBL1290752) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2ccc3occc3c2)cc1 Show InChI InChI=1S/C24H25ClN2O3/c25-21-4-1-18(2-5-21)16-26-10-8-24(9-11-26)17-27(12-14-30-24)23(28)20-3-6-22-19(15-20)7-13-29-22/h1-7,13,15H,8-12,14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417458 (CHEMBL1289865) Show SMILES CC(C)c1nc(cs1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C22H28ClN3O2S/c1-16(2)20-24-19(14-29-20)21(27)26-11-12-28-22(15-26)7-9-25(10-8-22)13-17-3-5-18(23)6-4-17/h3-6,14,16H,7-13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50225551 (CHEMBL392378 | N-adamantan-1-ylmethyl-2-chloro-5-(...) Show SMILES Clc1ccc(NC2CCCNC2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2 |w:6.5,TLB:17:18:21:25.23.24,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C23H32ClN3O/c24-21-4-3-18(27-19-2-1-5-25-13-19)9-20(21)22(28)26-14-23-10-15-6-16(11-23)8-17(7-15)12-23/h3-4,9,15-17,19,25,27H,1-2,5-8,10-14H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...				J Med Chem 50: 5882-5 (2007) Article DOI: 10.1021/jm700949w BindingDB Entry DOI: 10.7270/Q2HQ3ZM9
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50225550 (CHEMBL392558 | N-adamantan-1-ylmethyl-2-chloro-5-p...) Show SMILES Clc1ccc(CC2CCCNC2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2 |w:6.5,TLB:17:18:21:25.23.24,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H33ClN2O/c25-22-4-3-16(6-17-2-1-5-26-14-17)10-21(22)23(28)27-15-24-11-18-7-19(12-24)9-20(8-18)13-24/h3-4,10,17-20,26H,1-2,5-9,11-15H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...				J Med Chem 50: 5882-5 (2007) Article DOI: 10.1021/jm700949w BindingDB Entry DOI: 10.7270/Q2HQ3ZM9
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417435 (CHEMBL1289314) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2cnsn2)cc1 Show InChI InChI=1S/C18H21ClN4O2S/c19-15-3-1-14(2-4-15)12-22-7-5-18(6-8-22)13-23(9-10-25-18)17(24)16-11-20-26-21-16/h1-4,11H,5-10,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417455 (CHEMBL1290753) Show SMILES Cc1ccc(o1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C21H25ClN2O3/c1-16-2-7-19(27-16)20(25)24-12-13-26-21(15-24)8-10-23(11-9-21)14-17-3-5-18(22)6-4-17/h2-7H,8-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417455 (CHEMBL1290753) Show SMILES Cc1ccc(o1)C(=O)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 Show InChI InChI=1S/C21H25ClN2O3/c1-16-2-7-19(27-16)20(25)24-12-13-26-21(15-24)8-10-23(11-9-21)14-17-3-5-18(22)6-4-17/h2-7H,8-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417437 (CHEMBL1289544) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2cscn2)cc1 Show InChI InChI=1S/C19H22ClN3O2S/c20-16-3-1-15(2-4-16)11-22-7-5-19(6-8-22)13-23(9-10-25-19)18(24)17-12-26-14-21-17/h1-4,12,14H,5-11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50411436 (CHEMBL235581) Show SMILES Clc1ccc(CC2CCNCC2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.23.24,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24| Show InChI InChI=1S/C24H33ClN2O/c25-22-2-1-17(7-16-3-5-26-6-4-16)11-21(22)23(28)27-15-24-12-18-8-19(13-24)10-20(9-18)14-24/h1-2,11,16,18-20,26H,3-10,12-15H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...				J Med Chem 50: 5882-5 (2007) Article DOI: 10.1021/jm700949w BindingDB Entry DOI: 10.7270/Q2HQ3ZM9
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417434 (CHEMBL1289082) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2cccs2)cc1 Show InChI InChI=1S/C20H23ClN2O2S/c21-17-5-3-16(4-6-17)14-22-9-7-20(8-10-22)15-23(11-12-25-20)19(24)18-2-1-13-26-18/h1-6,13H,7-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417448 (CHEMBL1289202) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2ccoc2)cc1 Show InChI InChI=1S/C20H23ClN2O3/c21-18-3-1-16(2-4-18)13-22-8-6-20(7-9-22)15-23(10-12-26-20)19(24)17-5-11-25-14-17/h1-5,11,14H,6-10,12-13,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417447 (CHEMBL1289081) Show SMILES Clc1ccc(CN2CCC3(CC2)CN(CCO3)C(=O)c2ccco2)cc1 Show InChI InChI=1S/C20H23ClN2O3/c21-17-5-3-16(4-6-17)14-22-9-7-20(8-10-22)15-23(11-13-26-20)19(24)18-2-1-12-25-18/h1-6,12H,7-11,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417454 (CHEMBL1290634) Show SMILES CCOc1ccccc1C(=O)N1CCC2(CCN(Cc3ccccc3)CC2)CC1 Show InChI InChI=1S/C25H32N2O2/c1-2-29-23-11-7-6-10-22(23)24(28)27-18-14-25(15-19-27)12-16-26(17-13-25)20-21-8-4-3-5-9-21/h3-11H,2,12-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 94 total )  |  Next  |  Last  >>

Jump to: