Found 31 hits with Last Name = 'tirelli' and Initial = 'n' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309775
(5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)Show InChI InChI=1S/C18H18N4O/c1-11(2)9-10-19-13-7-8-14-17-16(13)18(23)12-5-3-4-6-15(12)22(17)21-20-14/h3-8,11,19H,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309777
(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1ccccc31 Show InChI InChI=1S/C17H17N5O2/c1-22(2,24)10-9-18-12-7-8-13-16-15(12)17(23)11-5-3-4-6-14(11)21(16)20-19-13/h3-8,18H,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309780
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3nnn2c13 Show InChI InChI=1S/C18H19N5O3/c1-23(2,25)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(26-3)4-7-15(12)22(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309779
(5-(4-methoxyphenylamino)-6H-[1,2,3]triazolo[4,5,1-...)Show InChI InChI=1S/C20H14N4O2/c1-26-13-8-6-12(7-9-13)21-15-10-11-16-19-18(15)20(25)14-4-2-3-5-17(14)24(19)23-22-16/h2-11,21H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309771
(8-bromo-5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,...)Show InChI InChI=1S/C18H17BrN4O/c1-10(2)7-8-20-13-4-5-14-17-16(13)18(24)12-9-11(19)3-6-15(12)23(17)22-21-14/h3-6,9-10,20H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309766
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show InChI InChI=1S/C18H19N5O2/c1-22(2)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(25-3)4-7-15(12)23(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309778
(5-(2-(dimethylamino)ethylamino)-8-bromo-6H-[1,2,3]...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1cc(Br)ccc31 Show InChI InChI=1S/C17H16BrN5O2/c1-23(2,25)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)22(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309774
(5-(3-hydroxypropylamino)-8-bromo-6H-[1,2,3]triazol...)Show InChI InChI=1S/C16H13BrN4O2/c17-9-2-5-13-10(8-9)16(23)14-11(18-6-1-7-22)3-4-12-15(14)21(13)20-19-12/h2-5,8,18,22H,1,6-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309777
(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1ccccc31 Show InChI InChI=1S/C17H17N5O2/c1-22(2,24)10-9-18-12-7-8-13-16-15(12)17(23)11-5-3-4-6-14(11)21(16)20-19-13/h3-8,18H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 167 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309768
(5-(2-(dimethylamino)ethylamino)-8-fluoro-6H-[1,2,3...)Show InChI InChI=1S/C17H16FN5O/c1-22(2)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)23(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309776
(5-(3-hydroxypropylamino)-6H-[1,2,3]triazolo[4,5,1-...)Show InChI InChI=1S/C16H14N4O2/c21-9-3-8-17-11-6-7-12-15-14(11)16(22)10-4-1-2-5-13(10)20(15)19-18-12/h1-2,4-7,17,21H,3,8-9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 203 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309773
(5-(3-hydroxypropylamino)-8-methoxy-6H-[1,2,3]triaz...)Show InChI InChI=1S/C17H16N4O3/c1-24-10-3-6-14-11(9-10)17(23)15-12(18-7-2-8-22)4-5-13-16(15)21(14)20-19-13/h3-6,9,18,22H,2,7-8H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309780
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3nnn2c13 Show InChI InChI=1S/C18H19N5O3/c1-23(2,25)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(26-3)4-7-15(12)22(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 328 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309772
(8-methoxy-5-(phenethylamino)-6H-[1,2,3]triazolo[4,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCCc3ccccc3)ccc3nnn2c13 Show InChI InChI=1S/C22H18N4O2/c1-28-15-7-10-19-16(13-15)22(27)20-17(8-9-18-21(20)26(19)25-24-18)23-12-11-14-5-3-2-4-6-14/h2-10,13,23H,11-12H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309775
(5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)Show InChI InChI=1S/C18H18N4O/c1-11(2)9-10-19-13-7-8-14-17-16(13)18(23)12-5-3-4-6-15(12)22(17)21-20-14/h3-8,11,19H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309776
(5-(3-hydroxypropylamino)-6H-[1,2,3]triazolo[4,5,1-...)Show InChI InChI=1S/C16H14N4O2/c21-9-3-8-17-11-6-7-12-15-14(11)16(22)10-4-1-2-5-13(10)20(15)19-18-12/h1-2,4-7,17,21H,3,8-9H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 483 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309778
(5-(2-(dimethylamino)ethylamino)-8-bromo-6H-[1,2,3]...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1cc(Br)ccc31 Show InChI InChI=1S/C17H16BrN5O2/c1-23(2,25)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)22(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 507 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309773
(5-(3-hydroxypropylamino)-8-methoxy-6H-[1,2,3]triaz...)Show InChI InChI=1S/C17H16N4O3/c1-24-10-3-6-14-11(9-10)17(23)15-12(18-7-2-8-22)4-5-13-16(15)21(14)20-19-13/h3-6,9,18,22H,2,7-8H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 517 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309770
(5-(phenethylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)Show InChI InChI=1S/C21H16N4O/c26-21-15-8-4-5-9-18(15)25-20-17(23-24-25)11-10-16(19(20)21)22-13-12-14-6-2-1-3-7-14/h1-11,22H,12-13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 567 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309771
(8-bromo-5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,...)Show InChI InChI=1S/C18H17BrN4O/c1-10(2)7-8-20-13-4-5-14-17-16(13)18(24)12-9-11(19)3-6-15(12)23(17)22-21-14/h3-6,9-10,20H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 767 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309767
(5-(2-(dimethylamino)ethylamino)-8-bromo-6H-[1,2,3]...)Show InChI InChI=1S/C17H16BrN5O/c1-22(2)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)23(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309768
(5-(2-(dimethylamino)ethylamino)-8-fluoro-6H-[1,2,3...)Show InChI InChI=1S/C17H16FN5O/c1-22(2)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)23(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 783 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309779
(5-(4-methoxyphenylamino)-6H-[1,2,3]triazolo[4,5,1-...)Show InChI InChI=1S/C20H14N4O2/c1-26-13-8-6-12(7-9-13)21-15-10-11-16-19-18(15)20(25)14-4-2-3-5-17(14)24(19)23-22-16/h2-11,21H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 808 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309774
(5-(3-hydroxypropylamino)-8-bromo-6H-[1,2,3]triazol...)Show InChI InChI=1S/C16H13BrN4O2/c17-9-2-5-13-10(8-9)16(23)14-11(18-6-1-7-22)3-4-12-15(14)21(13)20-19-12/h2-5,8,18,22H,1,6-7H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 987 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309766
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show InChI InChI=1S/C18H19N5O2/c1-22(2)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(25-3)4-7-15(12)23(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309767
(5-(2-(dimethylamino)ethylamino)-8-bromo-6H-[1,2,3]...)Show InChI InChI=1S/C17H16BrN5O/c1-22(2)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)23(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309769
(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)Show InChI InChI=1S/C17H17N5O/c1-21(2)10-9-18-12-7-8-13-16-15(12)17(23)11-5-3-4-6-14(11)22(16)20-19-13/h3-8,18H,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309769
(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)Show InChI InChI=1S/C17H17N5O/c1-21(2)10-9-18-12-7-8-13-16-15(12)17(23)11-5-3-4-6-14(11)22(16)20-19-13/h3-8,18H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309770
(5-(phenethylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)Show InChI InChI=1S/C21H16N4O/c26-21-15-8-4-5-9-18(15)25-20-17(23-24-25)11-10-16(19(20)21)22-13-12-14-6-2-1-3-7-14/h1-11,22H,12-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309772
(8-methoxy-5-(phenethylamino)-6H-[1,2,3]triazolo[4,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCCc3ccccc3)ccc3nnn2c13 Show InChI InChI=1S/C22H18N4O2/c1-28-15-7-10-19-16(13-15)22(27)20-17(8-9-18-21(20)26(19)25-24-18)23-12-11-14-5-3-2-4-6-14/h2-10,13,23H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |