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Compile Data Set for Download or QSAR

Found 3 hits with Last Name = 'tomishi' and Initial = 't'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50036754
PNG
((1Z)-N'-(aminosulfonyl)-3-[({2-[(diaminomethylene)...)
Show SMILES [#7]\[#6](-[#7])=[#7]/c1nc(-[#6]-[#16]-[#6]-[#6]-[#6](=[#7])-[#7]S([#7])(=O)=O)cs1
Show InChI InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
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PC cid
PC sid
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PubMed
n/an/a 300n/an/an/an/an/an/a



Fujisawa Pharmaceutical Company

Curated by ChEMBL


Assay Description
Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atrium


J Med Chem 37: 57-66 (1994)


BindingDB Entry DOI: 10.7270/Q2FN16TT
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50036755
PNG
(CHEMBL556048 | N-[6-(2-Guanidino-thiazol-4-yl)-pyr...)
Show SMILES [#6]-[#6](=O)-[#7]-[#6]-c1cccc(n1)-c1csc(\[#7]=[#6](/[#7])-[#7])n1
Show InChI InChI=1S/C12H14N6OS/c1-7(19)15-5-8-3-2-4-9(16-8)10-6-20-12(17-10)18-11(13)14/h2-4,6H,5H2,1H3,(H,15,19)(H4,13,14,17,18)
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PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Company

Curated by ChEMBL


Assay Description
Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atrium


J Med Chem 37: 57-66 (1994)


BindingDB Entry DOI: 10.7270/Q2FN16TT
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM22893
PNG
(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Show SMILES CN\C([CH-][N+]([O-])=O)=[NH+]/CCSCc1ccc(CN(C)C)o1
Show InChI InChI=1S/C13H21N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9H,6-8,10H2,1-3H3,(H,14,15)/q-1/p+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Company

Curated by ChEMBL


Assay Description
Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atrium


J Med Chem 37: 57-66 (1994)


BindingDB Entry DOI: 10.7270/Q2FN16TT
More data for this
Ligand-Target Pair