Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H2 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50036754 ((1Z)-N'-(aminosulfonyl)-3-[({2-[(diaminomethylene)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Company Curated by ChEMBL | Assay Description Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atrium | J Med Chem 37: 57-66 (1994) BindingDB Entry DOI: 10.7270/Q2FN16TT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50036755 (CHEMBL556048 | N-[6-(2-Guanidino-thiazol-4-yl)-pyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Company Curated by ChEMBL | Assay Description Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atrium | J Med Chem 37: 57-66 (1994) BindingDB Entry DOI: 10.7270/Q2FN16TT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Cavia porcellus (domestic guinea pig)) | BDBM22893 (CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujisawa Pharmaceutical Company Curated by ChEMBL | Assay Description Compound was tested for H2 receptor antagonistic activity against histamine stimulated chronotropic response in isolated guinea pig right atrium | J Med Chem 37: 57-66 (1994) BindingDB Entry DOI: 10.7270/Q2FN16TT | |||||||||||
More data for this Ligand-Target Pair |