Compile Data Set for Download or QSAR

Found 272 hits with Last Name = 'trivedi' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434486 (CHEMBL2385548) Show SMILES O=C1N(Cc2ccccc2-c2cncnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C34H28N6O2/c35-18-23-5-7-24(8-6-23)32-17-27-15-26-16-29(39-13-11-36-12-14-39)9-10-31(26)40(34(41)33(27)42-32)21-25-3-1-2-4-30(25)28-19-37-22-38-20-28/h1-10,16-17,19-20,22,36H,11-15,21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50276903 (CHEMBL4171764) Show SMILES Brc1cccc(Nc2ncnc3sc4CCCCc4c23)c1 Show InChI InChI=1S/C16H14BrN3S/c17-10-4-3-5-11(8-10)20-15-14-12-6-1-2-7-13(12)21-16(14)19-9-18-15/h3-5,8-9H,1-2,6-7H2,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Inhibition of EGFR1 (unknown origin) after 1 hr in presence of adenosine 5'[gamma-33P]triphosphate by microbeta microplate counting method				Eur J Med Chem 138: 1053-1065 (2017) Article DOI: 10.1016/j.ejmech.2017.07.028 BindingDB Entry DOI: 10.7270/Q2794760
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362173 (CHEMBL1938685) Show SMILES N#Cc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1 Show InChI InChI=1S/C25H21N5O/c26-16-17-1-3-18(4-2-17)23-15-20-13-19-14-21(29-10-7-27-8-11-29)5-6-22(19)30-12-9-28-25(30)24(20)31-23/h1-6,9,12,14-15,27H,7-8,10-11,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434488 (CHEMBL2385549) Show SMILES O=C1N(Cc2ccccc2-c2cncnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)C1CCNCC1 Show InChI InChI=1S/C35H29N5O2/c36-18-23-5-7-25(8-6-23)33-17-29-16-28-15-26(24-11-13-37-14-12-24)9-10-32(28)40(35(41)34(29)42-33)21-27-3-1-2-4-31(27)30-19-38-22-39-20-30/h1-10,15,17,19-20,22,24,37H,11-14,16,21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362175 (CHEMBL1938687) Show SMILES N#Cc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1 Show InChI InChI=1S/C24H20N6O/c25-14-16-1-3-17(4-2-16)22-13-19-11-18-12-20(29-9-7-26-8-10-29)5-6-21(18)30-15-27-28-24(30)23(19)31-22/h1-6,12-13,15,26H,7-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434494 (CHEMBL2385542) Show SMILES COc1cncc(c1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C36H31N5O3/c1-43-31-18-29(21-39-22-31)32-5-3-2-4-26(32)23-41-33-11-10-30(40-14-12-38-13-15-40)17-27(33)16-28-19-34(44-35(28)36(41)42)25-8-6-24(20-37)7-9-25/h2-11,17-19,21-22,38H,12-16,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434489 (CHEMBL2385547) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cncnc3)C(=O)c2o1)N1CCNCC1 Show InChI InChI=1S/C33H28ClN5O2/c34-27-7-5-22(6-8-27)31-17-25-15-24-16-28(38-13-11-35-12-14-38)9-10-30(24)39(33(40)32(25)41-31)20-23-3-1-2-4-29(23)26-18-36-21-37-19-26/h1-10,16-19,21,35H,11-15,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434489 (CHEMBL2385547) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cncnc3)C(=O)c2o1)N1CCNCC1 Show InChI InChI=1S/C33H28ClN5O2/c34-27-7-5-22(6-8-27)31-17-25-15-24-16-28(38-13-11-35-12-14-38)9-10-30(24)39(33(40)32(25)41-31)20-23-3-1-2-4-29(23)26-18-36-21-37-19-26/h1-10,16-19,21,35H,11-15,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434490 (CHEMBL2385546) Show SMILES COc1ccncc1-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C36H31N5O3/c1-43-33-12-13-39-22-31(33)30-5-3-2-4-26(30)23-41-32-11-10-29(40-16-14-38-15-17-40)19-27(32)18-28-20-34(44-35(28)36(41)42)25-8-6-24(21-37)7-9-25/h2-13,19-20,22,38H,14-18,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362172 (CHEMBL1938684) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1 Show InChI InChI=1S/C24H21ClN4O/c25-19-3-1-16(2-4-19)22-15-18-13-17-14-20(28-10-7-26-8-11-28)5-6-21(17)29-12-9-27-24(29)23(18)30-22/h1-6,9,12,14-15,26H,7-8,10-11,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045412 (CHEMBL3314153) Show SMILES Clc1cc(ccc1N1CCNCC1)-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H20ClN5O/c25-20-15-19(5-6-21(20)29-12-9-27-10-13-29)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362131 (CHEMBL1940652) Show SMILES COc1ccncc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C35H31N5O3/c1-42-33-16-17-38-23-31(33)30-5-3-2-4-27(30)24-40(29-12-10-28(11-13-29)39-20-18-37-19-21-39)35(41)34-15-14-32(43-34)26-8-6-25(22-36)7-9-26/h2-17,23,37H,18-21,24H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362124 (CHEMBL1940645) Show SMILES O=C(N(Cc1ccccc1-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C36H29N5O2/c37-23-26-5-9-28(10-6-26)33-4-2-1-3-30(33)25-41(32-15-13-31(14-16-32)40-21-19-39-20-22-40)36(42)35-18-17-34(43-35)29-11-7-27(24-38)8-12-29/h1-18,39H,19-22,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434491 (CHEMBL2385545) Show SMILES COc1ncccc1-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C36H31N5O3/c1-43-35-31(7-4-14-39-35)30-6-3-2-5-26(30)23-41-32-13-12-29(40-17-15-38-16-18-40)20-27(32)19-28-21-33(44-34(28)36(41)42)25-10-8-24(22-37)9-11-25/h2-14,20-21,38H,15-19,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434487 (CHEMBL2385550) Show SMILES FC1(F)c2cc(oc2C(=O)N(Cc2ccccc2-c2cncnc2)c2ccc(cc12)C1CCNCC1)-c1ccc(cc1)C#N Show InChI InChI=1S/C35H27F2N5O2/c36-35(37)29-15-25(23-11-13-39-14-12-23)9-10-31(29)42(20-26-3-1-2-4-28(26)27-18-40-21-41-19-27)34(43)33-30(35)16-32(44-33)24-7-5-22(17-38)6-8-24/h1-10,15-16,18-19,21,23,39H,11-14,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362114 (CHEMBL1940518) Show SMILES O=C(N(Cc1ccccc1-c1ccccc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C35H30N4O2/c36-24-26-10-12-28(13-11-26)33-18-19-34(41-33)35(40)39(31-16-14-30(15-17-31)38-22-20-37-21-23-38)25-29-8-4-5-9-32(29)27-6-2-1-3-7-27/h1-19,37H,20-23,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362137 (CHEMBL1940658) Show SMILES COc1ccncc1-c1ncccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C34H30N6O3/c1-42-31-14-16-37-22-29(31)33-26(3-2-15-38-33)23-40(28-10-8-27(9-11-28)39-19-17-36-18-20-39)34(41)32-13-12-30(43-32)25-6-4-24(21-35)5-7-25/h2-16,22,36H,17-20,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362127 (CHEMBL1940648) Show SMILES O=C(N(Cc1ccccc1-c1cccnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C34H29N5O2/c35-22-25-7-9-26(10-8-25)32-15-16-33(41-32)34(40)39(30-13-11-29(12-14-30)38-20-18-36-19-21-38)24-28-4-1-2-6-31(28)27-5-3-17-37-23-27/h1-17,23,36H,18-21,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362177 (CHEMBL1938689) Show SMILES Cc1cnc2-c3oc(cc3Cc3cc(ccc3-n12)N1CCNCC1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN4O/c1-16-15-28-25-24-19(14-23(31-24)17-2-4-20(26)5-3-17)12-18-13-21(6-7-22(18)30(16)25)29-10-8-27-9-11-29/h2-7,13-15,27H,8-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362174 (CHEMBL1938686) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1 Show InChI InChI=1S/C23H20ClN5O/c24-18-3-1-15(2-4-18)21-13-17-11-16-12-19(28-9-7-25-8-10-28)5-6-20(16)29-14-26-27-23(29)22(17)30-21/h1-6,12-14,25H,7-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434504 (CHEMBL2385532) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(CC=C)C(=O)c2o1)N1CCNCC1 Show InChI InChI=1S/C25H24ClN3O2/c1-2-11-29-22-8-7-21(28-12-9-27-10-13-28)15-18(22)14-19-16-23(31-24(19)25(29)30)17-3-5-20(26)6-4-17/h2-8,15-16,27H,1,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362117 (CHEMBL1940521) Show SMILES Fc1ccccc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C35H29FN4O2/c36-32-8-4-3-7-31(32)30-6-2-1-5-27(30)24-40(29-15-13-28(14-16-29)39-21-19-38-20-22-39)35(41)34-18-17-33(42-34)26-11-9-25(23-37)10-12-26/h1-18,38H,19-22,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362136 (CHEMBL1940657) Show SMILES COc1ccccc1-c1ncccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C35H31N5O3/c1-42-32-7-3-2-6-30(32)34-27(5-4-18-38-34)24-40(29-14-12-28(13-15-29)39-21-19-37-20-22-39)35(41)33-17-16-31(43-33)26-10-8-25(23-36)9-11-26/h2-18,37H,19-22,24H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362126 (CHEMBL1940647) Show SMILES COc1cccc(c1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C36H32N4O3/c1-42-32-7-4-6-28(23-32)33-8-3-2-5-29(33)25-40(31-15-13-30(14-16-31)39-21-19-38-20-22-39)36(41)35-18-17-34(43-35)27-11-9-26(24-37)10-12-27/h2-18,23,38H,19-22,25H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362120 (CHEMBL1940524) Show SMILES O=C(N(Cc1ccccc1-c1ccncc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C34H29N5O2/c35-23-25-5-7-27(8-6-25)32-13-14-33(41-32)34(40)39(30-11-9-29(10-12-30)38-21-19-37-20-22-38)24-28-3-1-2-4-31(28)26-15-17-36-18-16-26/h1-18,37H,19-22,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045417 (CHEMBL3314148) Show SMILES Clc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C24H20ClN5O/c25-20-15-19(29-12-9-27-10-13-29)5-6-21(20)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362128 (CHEMBL1940649) Show SMILES O=C(N(Cc1ccccc1-c1ccccn1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C34H29N5O2/c35-23-25-8-10-26(11-9-25)32-16-17-33(41-32)34(40)39(29-14-12-28(13-15-29)38-21-19-36-20-22-38)24-27-5-1-2-6-30(27)31-7-3-4-18-37-31/h1-18,36H,19-22,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045423 (CHEMBL3314142) Show SMILES Clc1ccc(cc1)-c1ccc(o1)-c1nncn1-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C22H20ClN5O/c23-17-3-1-16(2-4-17)20-9-10-21(29-20)22-26-25-15-28(22)19-7-5-18(6-8-19)27-13-11-24-12-14-27/h1-10,15,24H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434496 (CHEMBL2385540) Show SMILES Fc1cncc(c1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C35H28FN5O2/c36-29-16-28(20-39-21-29)31-4-2-1-3-25(31)22-41-32-10-9-30(40-13-11-38-12-14-40)17-26(32)15-27-18-33(43-34(27)35(41)42)24-7-5-23(19-37)6-8-24/h1-10,16-18,20-21,38H,11-15,22H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434499 (CHEMBL2385537) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3NC(=O)c2o1)C1CCNCC1 Show InChI InChI=1S/C23H21ClN2O2/c24-19-4-1-15(2-5-19)21-13-18-12-17-11-16(14-7-9-25-10-8-14)3-6-20(17)26-23(27)22(18)28-21/h1-6,11,13-14,25H,7-10,12H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362176 (CHEMBL1938688) Show SMILES Fc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1 Show InChI InChI=1S/C23H20FN5O/c24-18-3-1-15(2-4-18)21-13-17-11-16-12-19(28-9-7-25-8-10-28)5-6-20(16)29-14-26-27-23(29)22(17)30-21/h1-6,12-14,25H,7-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045418 (CHEMBL3314147) Show SMILES Fc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C24H20FN5O/c25-20-15-19(29-12-9-27-10-13-29)5-6-21(20)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50470576 (CHEMBL4294949) Show SMILES Nc1ccccc1NC(=O)c1ccc(CN2CC(=C)c3ccccc3C2=O)cc1 Show InChI InChI=1S/C24H21N3O2/c1-16-14-27(24(29)20-7-3-2-6-19(16)20)15-17-10-12-18(13-11-17)23(28)26-22-9-5-4-8-21(22)25/h2-13H,1,14-15,25H2,(H,26,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				Eur J Med Chem 157: 1127-1142 (2018) Article DOI: 10.1016/j.ejmech.2018.08.081 BindingDB Entry DOI: 10.7270/Q2KW5JQS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045416 (CHEMBL3314149) Show SMILES Cc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C25H23N5O/c1-18-16-21(29-13-10-27-11-14-29)6-7-22(18)30-15-12-28-25(30)24-9-8-23(31-24)20-4-2-19(17-26)3-5-20/h2-9,12,15-16,27H,10-11,13-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362179 (CHEMBL1938691) Show SMILES Clc1ccc(cc1)-c1cc2COc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1 Show InChI InChI=1S/C24H21ClN4O2/c25-18-3-1-16(2-4-18)21-13-17-15-30-22-14-19(28-10-7-26-8-11-28)5-6-20(22)29-12-9-27-24(29)23(17)31-21/h1-6,9,12-14,26H,7-8,10-11,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...				Bioorg Med Chem Lett 22: 1068-72 (2012) Article DOI: 10.1016/j.bmcl.2011.11.113 BindingDB Entry DOI: 10.7270/Q23J3DDJ
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362125 (CHEMBL1940646) Show SMILES O=C(N(Cc1ccccc1-c1cccc(c1)C#N)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C36H29N5O2/c37-23-26-8-10-28(11-9-26)34-16-17-35(43-34)36(42)41(32-14-12-31(13-15-32)40-20-18-39-19-21-40)25-30-5-1-2-7-33(30)29-6-3-4-27(22-29)24-38/h1-17,22,39H,18-21,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362135 (CHEMBL1940656) Show SMILES COc1ccccc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C36H32N4O3/c1-42-34-9-5-4-8-32(34)31-7-3-2-6-28(31)25-40(30-16-14-29(15-17-30)39-22-20-38-21-23-39)36(41)35-19-18-33(43-35)27-12-10-26(24-37)11-13-27/h2-19,38H,20-23,25H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362130 (CHEMBL1940651) Show SMILES COc1cncc(c1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C35H31N5O3/c1-42-31-20-28(22-38-23-31)32-5-3-2-4-27(32)24-40(30-12-10-29(11-13-30)39-18-16-37-17-19-39)35(41)34-15-14-33(43-34)26-8-6-25(21-36)7-9-26/h2-15,20,22-23,37H,16-19,24H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434495 (CHEMBL2385541) Show SMILES COc1cc(ccn1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(Cl)cc1)N1CCNCC1 Show InChI InChI=1S/C35H31ClN4O3/c1-42-33-21-24(12-13-38-33)30-5-3-2-4-25(30)22-40-31-11-10-29(39-16-14-37-15-17-39)19-26(31)18-27-20-32(43-34(27)35(40)41)23-6-8-28(36)9-7-23/h2-13,19-21,37H,14-18,22H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50470578 (CHEMBL4282111) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C14H21N3O3/c15-11-7-5-6-8-12(11)16-13(18)9-3-1-2-4-10-14(19)17-20/h5-8,20H,1-4,9-10,15H2,(H,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of His6-tagged HDAC3/SMRT (395 to 489 residues) (unknown origin) co-expressed in baculovirus infected sf9 cells using (FAM)-labeled acetyl...				Eur J Med Chem 157: 1127-1142 (2018) Article DOI: 10.1016/j.ejmech.2018.08.081 BindingDB Entry DOI: 10.7270/Q2KW5JQS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362123 (CHEMBL1940644) Show SMILES Cc1noc(C)c1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 |(5.23,-8.04,;5.69,-9.51,;4.77,-10.74,;5.66,-12,;7.14,-11.54,;8.37,-12.46,;7.15,-9.99,;8.41,-9.1,;9.75,-9.86,;11.08,-9.07,;11.05,-7.52,;9.71,-6.78,;8.4,-7.56,;7.06,-6.8,;7.04,-5.26,;5.7,-4.51,;5.69,-2.97,;4.38,-5.29,;3.9,-6.76,;2.35,-6.76,;1.87,-5.29,;3.13,-4.39,;.52,-4.57,;.47,-3.03,;-.88,-2.3,;-2.2,-3.11,;-2.14,-4.66,;-.79,-5.38,;-3.55,-2.39,;-4.91,-1.66,;8.37,-4.48,;9.71,-5.24,;11.03,-4.46,;11.02,-2.92,;9.66,-2.16,;8.35,-2.95,;12.34,-2.14,;13.68,-2.9,;15,-2.12,;14.99,-.58,;13.65,.18,;12.32,-.6,)| Show InChI InChI=1S/C34H31N5O3/c1-23-33(24(2)42-37-23)30-6-4-3-5-27(30)22-39(29-13-11-28(12-14-29)38-19-17-36-18-20-38)34(40)32-16-15-31(41-32)26-9-7-25(21-35)8-10-26/h3-16,36H,17-20,22H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434492 (CHEMBL2385544) Show SMILES O=C1N(Cc2ccccc2-c2cccnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C35H29N5O2/c36-21-24-7-9-25(10-8-24)33-20-29-18-28-19-30(39-16-14-37-15-17-39)11-12-32(28)40(35(41)34(29)42-33)23-27-4-1-2-6-31(27)26-5-3-13-38-22-26/h1-13,19-20,22,37H,14-18,23H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50434485 (CHEMBL2385543) Show SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cccnc3)C(=O)c2o1)N1CCNCC1 Show InChI InChI=1S/C34H29ClN4O2/c35-28-9-7-23(8-10-28)32-20-27-18-26-19-29(38-16-14-36-15-17-38)11-12-31(26)39(34(40)33(27)41-32)22-25-4-1-2-6-30(25)24-5-3-13-37-21-24/h1-13,19-21,36H,14-18,22H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...				Bioorg Med Chem Lett 23: 3262-6 (2013) Article DOI: 10.1016/j.bmcl.2013.03.109 BindingDB Entry DOI: 10.7270/Q2ZS2XX8
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045415 (CHEMBL3314150) Show SMILES Brc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1 Show InChI InChI=1S/C24H20BrN5O/c25-20-15-19(29-12-9-27-10-13-29)5-6-21(20)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045422 (CHEMBL3314143) Show SMILES N#Cc1ccc(cc1)-c1ccc(o1)-c1nncn1-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C23H20N6O/c24-15-17-1-3-18(4-2-17)21-9-10-22(30-21)23-27-26-16-29(23)20-7-5-19(6-8-20)28-13-11-25-12-14-28/h1-10,16,25H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50362133 (CHEMBL1940654) Show SMILES COc1cc(ccn1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C35H31N5O3/c1-42-34-22-27(16-17-38-34)31-5-3-2-4-28(31)24-40(30-12-10-29(11-13-30)39-20-18-37-19-21-39)35(41)33-15-14-32(43-33)26-8-6-25(23-36)7-9-26/h2-17,22,37H,18-21,24H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MK2				Bioorg Med Chem Lett 22: 65-70 (2011) Article DOI: 10.1016/j.bmcl.2011.11.074 BindingDB Entry DOI: 10.7270/Q2R78FNS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045373 (CHEMBL3315291) Show SMILES FC1(CCNCC1)c1ccc(cc1)-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C25H21FN4O/c26-25(11-13-28-14-12-25)20-5-7-21(8-6-20)30-16-15-29-24(30)23-10-9-22(31-23)19-3-1-18(17-27)2-4-19/h1-10,15-16,28H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045409 (CHEMBL3314156) Show SMILES Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)C1CCCNC1 Show InChI InChI=1S/C24H22ClN3O/c25-20-7-3-18(4-8-20)22-11-12-23(29-22)24-27-14-15-28(24)21-9-5-17(6-10-21)19-2-1-13-26-16-19/h3-12,14-15,19,26H,1-2,13,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045370 (CHEMBL3314140) Show SMILES Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C23H21ClN4O/c24-18-3-1-17(2-4-18)21-9-10-22(29-21)23-26-13-16-28(23)20-7-5-19(6-8-20)27-14-11-25-12-15-27/h1-10,13,16,25H,11-12,14-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045374 (CHEMBL3315290) Show SMILES OC1(CCNCC1)c1ccc(cc1)-n1ccnc1-c1ccc(o1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H22ClN3O2/c25-19-5-1-17(2-6-19)21-9-10-22(30-21)23-27-15-16-28(23)20-7-3-18(4-8-20)24(29)11-13-26-14-12-24/h1-10,15-16,26,29H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair

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