Compile Data Set for Download or QSAR

Found 68 hits with Last Name = 'villadsen' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor corepressor 1 (Homo sapiens (Human))	BDBM50354086 (FK-228 | Istodax | ROMIDEPSIN) Show SMILES C\C=C1/NC(=O)[C@@H](CS)NC(=O)[C@H](CC(=O)C[C@H](OC(=O)[C@@H](NC1=O)C(C)C)\C=C\CCS)C(C)C |r| Show InChI InChI=1S/C25H39N3O6S2/c1-6-19-23(31)28-21(15(4)5)25(33)34-17(9-7-8-10-35)11-16(29)12-18(14(2)3)22(30)27-20(13-36)24(32)26-19/h6-7,9,14-15,17-18,20-21,35-36H,8,10-13H2,1-5H3,(H,26,32)(H,27,30)(H,28,31)/b9-7+,19-6-/t17-,18-,20-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins				J Med Chem 56: 6512-20 (2013) Article DOI: 10.1021/jm4008449 BindingDB Entry DOI: 10.7270/Q27S7Q6R
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 3 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Nuclear receptor corepressor 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins				J Med Chem 56: 6512-20 (2013) Article DOI: 10.1021/jm4008449 BindingDB Entry DOI: 10.7270/Q27S7Q6R
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Nuclear receptor corepressor 1 (Homo sapiens (Human))	BDBM50377384 (AZUMAMIDE C) Show SMILES CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](CC=CCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |w:11.10| Show InChI InChI=1S/C27H38N4O7/c1-15(2)23-27(38)28-17(4)25(36)30-21(14-18-10-12-19(32)13-11-18)26(37)29-20(16(3)24(35)31-23)8-6-5-7-9-22(33)34/h5-6,10-13,15-17,20-21,23,32H,7-9,14H2,1-4H3,(H,28,38)(H,29,37)(H,30,36)(H,31,35)(H,33,34)/t16-,17+,20+,21+,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins				J Med Chem 56: 6512-20 (2013) Article DOI: 10.1021/jm4008449 BindingDB Entry DOI: 10.7270/Q27S7Q6R
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Nuclear receptor corepressor 1 (Homo sapiens (Human))	BDBM50372469 (AZUMAMIDE E) Show SMILES CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](CC=CCCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |w:11.10| Show InChI InChI=1S/C27H38N4O6/c1-16(2)23-27(37)28-18(4)25(35)30-21(15-19-11-7-5-8-12-19)26(36)29-20(17(3)24(34)31-23)13-9-6-10-14-22(32)33/h5-9,11-12,16-18,20-21,23H,10,13-15H2,1-4H3,(H,28,37)(H,29,36)(H,30,35)(H,31,34)(H,32,33)/t17-,18+,20+,21+,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human HDAC3/NcoR1 enzyme using flurogenic Ac-LeuGlyLys (Ac)-AMC as substrate after 15 to 30 mins				J Med Chem 56: 6512-20 (2013) Article DOI: 10.1021/jm4008449 BindingDB Entry DOI: 10.7270/Q27S7Q6R
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032270 (CHEMBL3352995) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H39N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h7-8,10-11,15-17,19,22,25,29H,4-6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/t17-,19-,22-,25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032267 (CHEMBL3352997) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h4-5,7-8,10-11,15-17,19,22,25,29H,6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b5-4-/t17-,19-,22-,25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032272 (CHEMBL3352994) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h9-12,15-16,18,20,23,31H,4-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t16-,18-,20-,23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032267 (CHEMBL3352997) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h4-5,7-8,10-11,15-17,19,22,25,29H,6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b5-4-/t17-,19-,22-,25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032272 (CHEMBL3352994) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h9-12,15-16,18,20,23,31H,4-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t16-,18-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032270 (CHEMBL3352995) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H39N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h7-8,10-11,15-17,19,22,25,29H,4-6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/t17-,19-,22-,25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50032270 (CHEMBL3352995) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H39N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h7-8,10-11,15-17,19,22,25,29H,4-6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/t17-,19-,22-,25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032266 (CHEMBL3352823) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h4-5,9-12,15-16,18,20,23,31H,6-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b5-4-/t16-,18-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032267 (CHEMBL3352997) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h4-5,7-8,10-11,15-17,19,22,25,29H,6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b5-4-/t17-,19-,22-,25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032266 (CHEMBL3352823) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h4-5,9-12,15-16,18,20,23,31H,6-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b5-4-/t16-,18-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032272 (CHEMBL3352994) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h9-12,15-16,18,20,23,31H,4-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t16-,18-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032266 (CHEMBL3352823) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h4-5,9-12,15-16,18,20,23,31H,6-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b5-4-/t16-,18-,20-,23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032266 (CHEMBL3352823) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h4-5,9-12,15-16,18,20,23,31H,6-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b5-4-/t16-,18-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032269 (CHEMBL3352992) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h5,7-11,15-17,19,22,25,29H,4,6,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b9-5+/t17-,19-,22-,25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032269 (CHEMBL3352992) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h5,7-11,15-17,19,22,25,29H,4,6,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b9-5+/t17-,19-,22-,25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032267 (CHEMBL3352997) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h4-5,7-8,10-11,15-17,19,22,25,29H,6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b5-4-/t17-,19-,22-,25-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032270 (CHEMBL3352995) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H39N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h7-8,10-11,15-17,19,22,25,29H,4-6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/t17-,19-,22-,25-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032271 (CHEMBL3352991) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h5,7,9-12,15-16,18,20,23,31H,4,6,8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b7-5+/t16-,18-,20-,23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032274 (CHEMBL3352996) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4-8,10-11,16-17,19-20,23H,9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/b8-5-/t17-,19-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032271 (CHEMBL3352991) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h5,7,9-12,15-16,18,20,23,31H,4,6,8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b7-5+/t16-,18-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032269 (CHEMBL3352992) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h5,7-11,15-17,19,22,25,29H,4,6,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b9-5+/t17-,19-,22-,25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032269 (CHEMBL3352992) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h5,7-11,15-17,19,22,25,29H,4,6,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b9-5+/t17-,19-,22-,25-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032271 (CHEMBL3352991) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h5,7,9-12,15-16,18,20,23,31H,4,6,8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b7-5+/t16-,18-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032274 (CHEMBL3352996) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4-8,10-11,16-17,19-20,23H,9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/b8-5-/t17-,19-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032273 (CHEMBL3352993) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4,6-7,10-11,16-17,19-20,23H,5,8-9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/t17-,19-,20-,23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032271 (CHEMBL3352991) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h5,7,9-12,15-16,18,20,23,31H,4,6,8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b7-5+/t16-,18-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50032266 (CHEMBL3352823) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h4-5,9-12,15-16,18,20,23,31H,6-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b5-4-/t16-,18-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50032274 (CHEMBL3352996) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4-8,10-11,16-17,19-20,23H,9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/b8-5-/t17-,19-,20-,23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032273 (CHEMBL3352993) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4,6-7,10-11,16-17,19-20,23H,5,8-9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/t17-,19-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032273 (CHEMBL3352993) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4,6-7,10-11,16-17,19-20,23H,5,8-9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/t17-,19-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50032267 (CHEMBL3352997) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h4-5,7-8,10-11,15-17,19,22,25,29H,6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b5-4-/t17-,19-,22-,25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032270 (CHEMBL3352995) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C28H39N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h7-8,10-11,15-17,19,22,25,29H,4-6,9,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/t17-,19-,22-,25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50032274 (CHEMBL3352996) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](C\C=C/CCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H36N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4-8,10-11,16-17,19-20,23H,9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/b8-5-/t17-,19-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50032272 (CHEMBL3352994) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h9-12,15-16,18,20,23,31H,4-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t16-,18-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032272 (CHEMBL3352994) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h9-12,15-16,18,20,23,31H,4-8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t16-,18-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50032273 (CHEMBL3352993) Show SMILES CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O |r| Show InChI InChI=1S/C26H38N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4,6-7,10-11,16-17,19-20,23H,5,8-9,12-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/t17-,19-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50032269 (CHEMBL3352992) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C28H37N5O6/c1-16(2)25-28(39)30-17(3)26(37)32-22(13-18-15-29-21-11-8-7-10-20(18)21)27(38)31-19(14-23(34)33-25)9-5-4-6-12-24(35)36/h5,7-11,15-17,19,22,25,29H,4,6,12-14H2,1-3H3,(H,30,39)(H,31,38)(H,32,37)(H,33,34)(H,35,36)/b9-5+/t17-,19-,22-,25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50032268 (CHEMBL3352990) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C26H36N4O6/c1-16(2)23-26(36)27-17(3)24(34)29-20(14-18-10-6-4-7-11-18)25(35)28-19(15-21(31)30-23)12-8-5-9-13-22(32)33/h4,6-8,10-12,16-17,19-20,23H,5,9,13-15H2,1-3H3,(H,27,36)(H,28,35)(H,29,34)(H,30,31)(H,32,33)/b12-8+/t17-,19-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50032271 (CHEMBL3352991) Show SMILES CC(C)[C@H]1NC(=O)C[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O)\C=C\CCCC(O)=O |r| Show InChI InChI=1S/C26H36N4O7/c1-15(2)23-26(37)27-16(3)24(35)29-20(13-17-9-11-19(31)12-10-17)25(36)28-18(14-21(32)30-23)7-5-4-6-8-22(33)34/h5,7,9-12,15-16,18,20,23,31H,4,6,8,13-14H2,1-3H3,(H,27,37)(H,28,36)(H,29,35)(H,30,32)(H,33,34)/b7-5+/t16-,18-,20-,23-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Denmark Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 mins				J Med Chem 57: 9644-57 (2014) Article DOI: 10.1021/jm501399d BindingDB Entry DOI: 10.7270/Q2FJ2JCG
					More data for this Ligand-Target Pair

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