Compile Data Set for Download or QSAR

Found 98 hits with Last Name = 'waldmeier' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311052 (CHEMBL1079870 | ethyl 3-fluoro-9H-benzo[f]imidazo[...) Show SMILES CCOC(=O)c1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C15H12FN5O2/c1-2-23-15(22)13-12-6-21-14(17-7-19-21)10-5-9(16)3-4-11(10)20(12)8-18-13/h3-5,7-8H,2,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311061 (3-(3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazo...) Show SMILES Cc1nc(no1)-c1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C15H10FN7O/c1-8-20-14(21-24-8)13-12-5-23-15(17-6-19-23)10-4-9(16)2-3-11(10)22(12)7-18-13/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311048 (10-chloro-3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Fc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C12H7ClFN5/c13-11-10-4-19-12(15-5-17-19)8-3-7(14)1-2-9(8)18(10)6-16-11/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311049 (10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1ccccc-21 Show InChI InChI=1S/C12H8ClN5/c13-11-10-5-18-12(14-6-16-18)8-3-1-2-4-9(8)17(10)7-15-11/h1-4,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311074 (4-fluoro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1c(F)cccc-21 Show InChI InChI=1S/C13H10FN5/c1-8-11-5-19-13(15-6-17-19)12-9(14)3-2-4-10(12)18(11)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86998 ((2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,3]...) Show SMILES Fc1ccc(c(F)c1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCCCC1)c1ccc(F)cc1F Show InChI InChI=1S/C25H18F5NO3/c26-14-4-6-17(20(29)10-14)25(18-7-5-15(27)11-21(18)30)33-22-12-16(19(28)13-23(22)34-25)24(32)31-8-2-1-3-9-31/h4-7,10-13H,1-3,8-9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311036 (10-chloro-3-(difluoromethyl)-9H-benzo[f]imidazo[1,...) Show SMILES FC(F)c1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C13H8ClF2N5/c14-11-10-4-21-13(17-5-19-21)8-3-7(12(15)16)1-2-9(8)20(10)6-18-11/h1-3,5-6,12H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311037 (10-chloro-3-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C1CC1 Show InChI InChI=1S/C15H12ClN5/c16-14-13-6-21-15(17-7-19-21)11-5-10(9-1-2-9)3-4-12(11)20(13)8-18-14/h3-5,7-9H,1-2,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311075 (4-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1c(Cl)cccc-21 Show InChI InChI=1S/C13H10ClN5/c1-8-11-5-19-13(15-6-17-19)12-9(14)3-2-4-10(12)18(11)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311033 (3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C12H7BrClN5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311057 (3-chloro-10-propyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES CCCc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H14ClN5/c1-2-3-12-14-7-21-15(17-8-19-21)11-6-10(16)4-5-13(11)20(14)9-18-12/h4-6,8-9H,2-3,7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311071 (3-(difluoromethoxy)-10-methyl-9H-benzo[f]imidazo[1...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(OC(F)F)ccc-21 Show InChI InChI=1S/C14H11F2N5O/c1-8-12-5-21-13(17-6-19-21)10-4-9(22-14(15)16)2-3-11(10)20(12)7-18-8/h2-4,6-7,14H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311035 (10-chloro-3-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C13H10ClN5/c1-8-2-3-10-9(4-8)13-15-6-17-19(13)5-11-12(14)16-7-18(10)11/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM87007 ((2-(2,4-dichlorophenyl)-6-fluoro-2-(4-methoxypheny...) Show SMILES COc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCCCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2FNO4/c1-32-18-8-5-16(6-9-18)26(20-10-7-17(27)13-21(20)28)33-23-14-19(22(29)15-24(23)34-26)25(31)30-11-3-2-4-12-30/h5-10,13-15H,2-4,11-12H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311047 (3,10-dichloro-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C12H7Cl2N5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311039 (10-chloro-N-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(NC3CC3)ccc-21 Show InChI InChI=1S/C15H13ClN6/c16-14-13-6-22-15(17-7-19-22)11-5-10(20-9-1-2-9)3-4-12(11)21(13)8-18-14/h3-5,7-9,20H,1-2,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311068 (3-(difluoromethyl)-10-methyl-9H-benzo[f]imidazo[1,...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C(F)F Show InChI InChI=1S/C14H11F2N5/c1-8-12-5-21-14(17-6-19-21)10-4-9(13(15)16)2-3-11(10)20(12)7-18-8/h2-4,6-7,13H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311034 (10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C#N Show InChI InChI=1S/C13H7ClN6/c14-12-11-5-20-13(16-6-18-20)9-3-8(4-15)1-2-10(9)19(11)7-17-12/h1-3,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311064 (10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1ccccc-21 Show InChI InChI=1S/C13H11N5/c1-9-12-6-18-13(14-7-16-18)10-4-2-3-5-11(10)17(12)8-15-9/h2-5,7-8H,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311054 (1-(3-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazo...) Show SMILES CCC(=O)c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H12ClN5O/c1-2-13(22)14-12-6-21-15(17-7-19-21)10-5-9(16)3-4-11(10)20(12)8-18-14/h3-5,7-8H,2,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311040 (CHEMBL1081493 | N-(10-chloro-9H-benzo[f]imidazo[1,...) Show SMILES CC(=O)Nc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C14H11ClN6O/c1-8(22)19-9-2-3-11-10(4-9)14-16-6-18-21(14)5-12-13(15)17-7-20(11)12/h2-4,6-7H,5H2,1H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM86984 ((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...) Show SMILES Fc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCOCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H17Cl2F2NO4/c25-15-3-6-18(19(26)11-15)24(14-1-4-16(27)5-2-14)32-21-12-17(20(28)13-22(21)33-24)23(30)29-7-9-31-10-8-29/h1-6,11-13H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86989 (1-(2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,...) Show SMILES Fc1ccc(c(F)c1)C1(Oc2cc(F)c(cc2O1)S(=O)(=O)N1CCC(F)(F)CC1)c1ccc(F)cc1F Show InChI InChI=1S/C24H16F7NO4S/c25-13-1-3-15(17(27)9-13)24(16-4-2-14(26)10-18(16)28)35-20-11-19(29)22(12-21(20)36-24)37(33,34)32-7-5-23(30,31)6-8-32/h1-4,9-12H,5-8H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311046 (3-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H10ClN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311065 (3-fluoro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C13H10FN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311056 (10-(1,1-difluoropropyl)-3-fluoro-9H-benzo[f]imidaz...) Show SMILES CCC(F)(F)c1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C15H12F3N5/c1-2-15(17,18)13-12-6-23-14(19-7-21-23)10-5-9(16)3-4-11(10)22(12)8-20-13/h3-5,7-8H,2,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86984 ((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...) Show SMILES Fc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCOCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H17Cl2F2NO4/c25-15-3-6-18(19(26)11-15)24(14-1-4-16(27)5-2-14)32-21-12-17(20(28)13-22(21)33-24)23(30)29-7-9-31-10-8-29/h1-6,11-13H,7-10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM87003 ((2-(2,4-dichlorophenyl)-6-fluoro-2-(4-fluorophenyl...) Show SMILES Fc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCCCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C25H19Cl2F2NO3/c26-16-6-9-19(20(27)12-16)25(15-4-7-17(28)8-5-15)32-22-13-18(21(29)14-23(22)33-25)24(31)30-10-2-1-3-11-30/h4-9,12-14H,1-3,10-11H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311062 (3-bromo-10-(thiophen-2-yl)-9H-benzo[f]imidazo[1,5-...) Show SMILES Brc1ccc-2c(c1)-c1ncnn1Cc1c(ncn-21)-c1cccs1 Show InChI InChI=1S/C16H10BrN5S/c17-10-3-4-12-11(6-10)16-18-8-20-22(16)7-13-15(19-9-21(12)13)14-2-1-5-23-14/h1-6,8-9H,7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86984 ((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...) Show SMILES Fc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCOCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H17Cl2F2NO4/c25-15-3-6-18(19(26)11-15)24(14-1-4-16(27)5-2-14)32-21-12-17(20(28)13-22(21)33-24)23(30)29-7-9-31-10-8-29/h1-6,11-13H,7-10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86995 ((2-(2,4-dichlorophenyl)-6-fluoro-2-(2-fluorophenyl...) Show SMILES Fc1ccccc1C1(Oc2cc(F)c(cc2O1)C(=O)N1CCOCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H17Cl2F2NO4/c25-14-5-6-16(18(26)11-14)24(17-3-1-2-4-19(17)27)32-21-12-15(20(28)13-22(21)33-24)23(30)29-7-9-31-10-8-29/h1-6,11-13H,7-10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311066 (3-iodo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]t...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(I)ccc-21 Show InChI InChI=1S/C13H10IN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311045 (3-bromo-10-(difluoromethyl)-9H-benzo[f]imidazo[1,5...) Show SMILES FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C13H8BrF2N5/c14-7-1-2-9-8(3-7)13-17-5-19-21(13)4-10-11(12(15)16)18-6-20(9)10/h1-3,5-6,12H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair				3D Structure (crystal)
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311044 (3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...) Show SMILES FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H8ClF2N5/c14-7-1-2-9-8(3-7)13-17-5-19-21(13)4-10-11(12(15)16)18-6-20(9)10/h1-3,5-6,12H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50310939 (3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C13H10BrN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311038 (10-chloro-3-phenyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)-c1ccccc1 Show InChI InChI=1S/C18H12ClN5/c19-17-16-9-24-18(20-10-22-24)14-8-13(12-4-2-1-3-5-12)6-7-15(14)23(16)11-21-17/h1-8,10-11H,9H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311050 (9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,...) Show SMILES C1c2cncn2-c2ccccc2-c2ncnn12 Show InChI InChI=1S/C12H9N5/c1-2-4-11-10(3-1)12-14-7-15-17(12)6-9-5-13-8-16(9)11/h1-5,7-8H,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311059 (3-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[...) Show SMILES Clc1ccc-2c(c1)-c1ncnn1Cc1c(ncn-21)C#N Show InChI InChI=1S/C13H7ClN6/c14-8-1-2-11-9(3-8)13-16-6-18-20(13)5-12-10(4-15)17-7-19(11)12/h1-3,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86992 ((2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,3]...) Show SMILES Fc1ccc(c(F)c1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCOCC1)c1ccc(F)cc1F Show InChI InChI=1S/C24H16F5NO4/c25-13-1-3-16(19(28)9-13)24(17-4-2-14(26)10-20(17)29)33-21-11-15(18(27)12-22(21)34-24)23(31)30-5-7-32-8-6-30/h1-4,9-12H,5-8H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86997 ((6-fluoro-2,2-bis(4-fluorophenyl)benzo[d][1,3]diox...) Show SMILES Fc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)C(=O)N1CCCCC1)c1ccc(F)cc1 Show InChI InChI=1S/C25H20F3NO3/c26-18-8-4-16(5-9-18)25(17-6-10-19(27)11-7-17)31-22-14-20(21(28)15-23(22)32-25)24(30)29-12-2-1-3-13-29/h4-11,14-15H,1-3,12-13H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311070 (3-methoxy-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,...) Show SMILES COc1ccc-2c(c1)-c1ncnn1Cc1c(C)ncn-21 Show InChI InChI=1S/C14H13N5O/c1-9-13-6-19-14(15-7-17-19)11-5-10(20-2)3-4-12(11)18(13)8-16-9/h3-5,7-8H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM29094 ((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...) Show SMILES CN=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1 |w:1.0,c:18| Show InChI InChI=1S/C23H20Cl2N4O2S/c1-26-23(28-32(30,31)20-13-11-19(25)12-14-20)29-15-21(16-5-3-2-4-6-16)22(27-29)17-7-9-18(24)10-8-17/h2-14,21H,15H2,1H3,(H,26,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311033 (3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C12H7BrClN5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha3beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM87009 (4-(2-(2,4-dichlorophenyl)-6-fluoro-2-(4-fluorophen...) Show SMILES Fc1ccc(cc1)C1(Oc2cc(F)c(cc2O1)S(=O)(=O)N1CCOCC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H17Cl2F2NO5S/c24-15-3-6-17(18(25)11-15)23(14-1-4-16(26)5-2-14)32-20-12-19(27)22(13-21(20)33-23)34(29,30)28-7-9-31-10-8-28/h1-6,11-13H,7-10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311067 (3,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(C)ccc-21 Show InChI InChI=1S/C14H13N5/c1-9-3-4-12-11(5-9)14-15-7-17-19(14)6-13-10(2)16-8-18(12)13/h3-5,7-8H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311058 (3-chloro-10-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...) Show SMILES Clc1ccc-2c(c1)-c1ncnn1Cc1c(ncn-21)C1CC1 Show InChI InChI=1S/C15H12ClN5/c16-10-3-4-12-11(5-10)15-17-7-19-21(15)6-13-14(9-1-2-9)18-8-20(12)13/h3-5,7-9H,1-2,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311063 (3-bromo-10-(1-methyl-1H-pyrazol-5-yl)-9H-benzo[f]i...) Show SMILES Cn1nccc1-c1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C16H12BrN7/c1-22-13(4-5-20-22)15-14-7-24-16(18-8-21-24)11-6-10(17)2-3-12(11)23(14)9-19-15/h2-6,8-9H,7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311051 (3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[...) Show SMILES Fc1ccc-2c(c1)-c1ncnn1Cc1cncn-21 Show InChI InChI=1S/C12H8FN5/c13-8-1-2-11-10(3-8)12-15-6-16-18(12)5-9-4-14-7-17(9)11/h1-4,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM86986 ((6-fluoro-2,2-diphenylbenzo[d][1,3]dioxol-5-yl)(pi...) Show SMILES Fc1cc2OC(Oc2cc1C(=O)N1CCCCC1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H22FNO3/c26-21-17-23-22(16-20(21)24(28)27-14-8-3-9-15-27)29-25(30-23,18-10-4-1-5-11-18)19-12-6-2-7-13-19/h1-2,4-7,10-13,16-17H,3,8-9,14-15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Med Chem 51: 2115-27 (2008) Article DOI: 10.1021/jm701487t BindingDB Entry DOI: 10.7270/Q26H4G0Z
					More data for this Ligand-Target Pair

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