Compile Data Set for Download or QSAR

Found 154 hits with Last Name = 'wang' and Initial = 'dy'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4552 (4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6113 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-{5-[(4-h...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2csc(CN3CCC(O)CC3)c2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H24Cl2N4O2S/c1-35-26-11-25(22(28)10-23(26)29)32-27-18(12-30)13-31-24-9-16(2-3-21(24)27)17-8-20(36-15-17)14-33-6-4-19(34)5-7-33/h2-3,8-11,13,15,19,34H,4-7,14H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6115 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-{5-[(4-h...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCC(O)CC3)s2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H24Cl2N4O2S/c1-35-25-12-24(21(28)11-22(25)29)32-27-17(13-30)14-31-23-10-16(2-4-20(23)27)26-5-3-19(36-26)15-33-8-6-18(34)7-9-33/h2-5,10-12,14,18,34H,6-9,15H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6108 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[5-(morp...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCOCC3)s2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4O2S/c1-33-24-12-23(20(27)11-21(24)28)31-26-17(13-29)14-30-22-10-16(2-4-19(22)26)25-5-3-18(35-25)15-32-6-8-34-9-7-32/h2-5,10-12,14H,6-9,15H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6107 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[5-(morp...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2csc(CN3CCOCC3)c2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4O2S/c1-33-25-11-24(21(27)10-22(25)28)31-26-18(12-29)13-30-23-9-16(2-3-20(23)26)17-8-19(35-15-17)14-32-4-6-34-7-5-32/h2-3,8-11,13,15H,4-7,14H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6112 (3-quinolinecarbonitrile analog 2a | 4-[(2,4-dichlo...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2csc(CN3CCN(C)CC3)c2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H25Cl2N5OS/c1-33-5-7-34(8-6-33)15-20-9-18(16-36-20)17-3-4-21-24(10-17)31-14-19(13-30)27(21)32-25-12-26(35-2)23(29)11-22(25)28/h3-4,9-12,14,16H,5-8,15H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6114 (3-quinolinecarbonitrile analog 2b | 4-[(2,4-dichlo...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCN(C)CC3)s2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H25Cl2N5OS/c1-33-7-9-34(10-8-33)16-19-4-6-26(36-19)17-3-5-20-23(11-17)31-15-18(14-30)27(20)32-24-13-25(35-2)22(29)12-21(24)28/h3-6,11-13,15H,7-10,16H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6116 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[5-(pipe...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCCCC3)s2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H24Cl2N4OS/c1-34-25-13-24(21(28)12-22(25)29)32-27-18(14-30)15-31-23-11-17(5-7-20(23)27)26-8-6-19(35-26)16-33-9-3-2-4-10-33/h5-8,11-13,15H,2-4,9-10,16H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6117 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[5-(thio...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCSCC3)s2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4OS2/c1-33-24-12-23(20(27)11-21(24)28)31-26-17(13-29)14-30-22-10-16(2-4-19(22)26)25-5-3-18(35-25)15-32-6-8-34-9-7-32/h2-5,10-12,14H,6-9,15H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6109 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[4-(morp...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2cc(CN3CCOCC3)cs2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4O2S/c1-33-24-11-23(20(27)10-21(24)28)31-26-18(12-29)13-30-22-9-17(2-3-19(22)26)25-8-16(15-35-25)14-32-4-6-34-7-5-32/h2-3,8-11,13,15H,4-7,14H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254432 (1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-ph...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H19N3O5S/c1-12-14(18-16(20)17-13-5-3-2-4-6-13)11-15(24-12)25(21,22)19-7-9-23-10-8-19/h2-6,11H,7-10H2,1H3,(H2,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254434 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) Show SMILES COCCN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1 Show InChI InChI=1S/C16H21N3O5S/c1-12-14(18-16(20)17-13-7-5-4-6-8-13)11-15(24-12)25(21,22)19(2)9-10-23-3/h4-8,11H,9-10H2,1-3H3,(H2,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271950 (CHEMBL4127821) Show SMILES OC(=O)C(\S)=C\c1c(F)cccc1Cl Show InChI InChI=1S/C9H6ClFO2S/c10-6-2-1-3-7(11)5(6)4-8(14)9(12)13/h1-4,14H,(H,12,13)/b8-4-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254343 ((S)-1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-...) Show SMILES C[C@H](NC(=O)Nc1cc(oc1C)S(=O)(=O)N1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C19H25N3O4S/c1-14(16-9-5-3-6-10-16)20-19(23)21-17-13-18(26-15(17)2)27(24,25)22-11-7-4-8-12-22/h3,5-6,9-10,13-14H,4,7-8,11-12H2,1-2H3,(H2,20,21,23)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271847 (CHEMBL4127736) Show SMILES OC(=O)C(\S)=C\c1c(Cl)cccc1Cl Show InChI InChI=1S/C9H6Cl2O2S/c10-6-2-1-3-7(11)5(6)4-8(14)9(12)13/h1-4,14H,(H,12,13)/b8-4-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271833 (CHEMBL3792857) Show SMILES OC(=O)C(\S)=C\c1c(Cl)ccc(Cl)c1Cl Show InChI InChI=1S/C9H5Cl3O2S/c10-5-1-2-6(11)8(12)4(5)3-7(15)9(13)14/h1-3,15H,(H,13,14)/b7-3-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lipoprotein lipase (Rattus norvegicus)	BDBM50254290 (1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H21N3O4S/c1-13-15(19-17(21)18-14-8-4-2-5-9-14)12-16(24-13)25(22,23)20-10-6-3-7-11-20/h2,4-5,8-9,12H,3,6-7,10-11H2,1H3,(H2,18,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271834 (CHEMBL3234727) Show SMILES OC(=O)C(S)c1ccccc1 Show InChI InChI=1S/C8H8O2S/c9-8(10)7(11)6-4-2-1-3-5-6/h1-5,7,11H,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271878 (CHEMBL4125829) Show SMILES OC(=O)C(\S)=C\c1c(F)cccc1F Show InChI InChI=1S/C9H6F2O2S/c10-6-2-1-3-7(11)5(6)4-8(14)9(12)13/h1-4,14H,(H,12,13)/b8-4-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254436 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1 Show InChI InChI=1S/C14H17N3O4S/c1-10-12(9-13(21-10)22(19,20)17(2)3)16-14(18)15-11-7-5-4-6-8-11/h4-9H,1-3H3,(H2,15,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254339 (1-(4-methoxyphenyl)-3-(2-methyl-5-(piperidin-1-yls...) Show SMILES COc1ccc(NC(=O)Nc2cc(oc2C)S(=O)(=O)N2CCCCC2)cc1 Show InChI InChI=1S/C18H23N3O5S/c1-13-16(20-18(22)19-14-6-8-15(25-2)9-7-14)12-17(26-13)27(23,24)21-10-4-3-5-11-21/h6-9,12H,3-5,10-11H2,1-2H3,(H2,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254432 (1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-ph...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H19N3O5S/c1-12-14(18-16(20)17-13-5-3-2-4-6-13)11-15(24-12)25(21,22)19-7-9-23-10-8-19/h2-6,11H,7-10H2,1H3,(H2,17,18,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254340 (1-(4-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccc(Cl)cc1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H20ClN3O4S/c1-12-15(20-17(22)19-14-7-5-13(18)6-8-14)11-16(25-12)26(23,24)21-9-3-2-4-10-21/h5-8,11H,2-4,9-10H2,1H3,(H2,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254339 (1-(4-methoxyphenyl)-3-(2-methyl-5-(piperidin-1-yls...) Show SMILES COc1ccc(NC(=O)Nc2cc(oc2C)S(=O)(=O)N2CCCCC2)cc1 Show InChI InChI=1S/C18H23N3O5S/c1-13-16(20-18(22)19-14-6-8-15(25-2)9-7-14)12-17(26-13)27(23,24)21-10-4-3-5-11-21/h6-9,12H,3-5,10-11H2,1-2H3,(H2,19,20,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254341 (1-(2-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1Cl)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H20ClN3O4S/c1-12-15(20-17(22)19-14-8-4-3-7-13(14)18)11-16(25-12)26(23,24)21-9-5-2-6-10-21/h3-4,7-8,11H,2,5-6,9-10H2,1H3,(H2,19,20,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254290 (1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H21N3O4S/c1-13-15(19-17(21)18-14-8-4-2-5-9-14)12-16(24-13)25(22,23)20-10-6-3-7-11-20/h2,4-5,8-9,12H,3,6-7,10-11H2,1H3,(H2,18,19,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254393 (1-benzhydryl-3-(2-methyl-5-(piperidin-1-ylsulfonyl...) Show SMILES Cc1oc(cc1NC(=O)NC(c1ccccc1)c1ccccc1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C24H27N3O4S/c1-18-21(17-22(31-18)32(29,30)27-15-9-4-10-16-27)25-24(28)26-23(19-11-5-2-6-12-19)20-13-7-3-8-14-20/h2-3,5-8,11-14,17,23H,4,9-10,15-16H2,1H3,(H2,25,26,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254340 (1-(4-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccc(Cl)cc1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H20ClN3O4S/c1-12-15(20-17(22)19-14-7-5-13(18)6-8-14)11-16(25-12)26(23,24)21-9-3-2-4-10-21/h5-8,11H,2-4,9-10H2,1H3,(H2,19,20,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271893 (CHEMBL4128221) Show SMILES OC(=O)C(\S)=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2S/c21-20(22)19(23)13-18-8-4-3-7-17(18)12-14-9-10-15-5-1-2-6-16(15)11-14/h1-11,13,23H,12H2,(H,21,22)/b19-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271889 (CHEMBL4129411) Show SMILES Cc1cccc(C)c1\C=C(/S)C(O)=O Show InChI InChI=1S/C11H12O2S/c1-7-4-3-5-8(2)9(7)6-10(14)11(12)13/h3-6,14H,1-2H3,(H,12,13)/b10-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271963 (CHEMBL1559342) Show SMILES CN1CCN(CC1)NC(=O)CN1C(=S)S\C(=C/c2c(Cl)cccc2Cl)C1=O Show InChI InChI=1S/C17H18Cl2N4O2S2/c1-21-5-7-22(8-6-21)20-15(24)10-23-16(25)14(27-17(23)26)9-11-12(18)3-2-4-13(11)19/h2-4,9H,5-8,10H2,1H3,(H,20,24)/b14-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Aeromonas hydrophila)	BDBM50271833 (CHEMBL3792857) Show SMILES OC(=O)C(\S)=C\c1c(Cl)ccc(Cl)c1Cl Show InChI InChI=1S/C9H5Cl3O2S/c10-5-1-2-6(11)8(12)4(5)3-7(15)9(13)14/h1-3,15H,(H,13,14)/b7-3-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Aeromonas hydrophila CphA using fluorogenic cephalosporin as substrate				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6111 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[4-(morp...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2cscc2CN2CCOCC2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4O2S/c1-33-25-10-24(21(27)9-22(25)28)31-26-17(11-29)12-30-23-8-16(2-3-19(23)26)20-15-35-14-18(20)13-32-4-6-34-7-5-32/h2-3,8-10,12,14-15H,4-7,13H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254434 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) Show SMILES COCCN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1 Show InChI InChI=1S/C16H21N3O5S/c1-12-14(18-16(20)17-13-7-5-4-6-8-13)11-15(24-12)25(21,22)19(2)9-10-23-3/h4-8,11H,9-10H2,1-3H3,(H2,17,18,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6118 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-[5-(morp...) Show SMILES COc1cc(Nc2c(cnc3ccc(cc23)-c2csc(CN3CCOCC3)c2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4O2S/c1-33-25-11-24(21(27)10-22(25)28)31-26-18(12-29)13-30-23-3-2-16(9-20(23)26)17-8-19(35-15-17)14-32-4-6-34-7-5-32/h2-3,8-11,13,15H,4-7,14H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254436 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1 Show InChI InChI=1S/C14H17N3O4S/c1-10-12(9-13(21-10)22(19,20)17(2)3)16-14(18)15-11-7-5-4-6-8-11/h4-9H,1-3H3,(H2,15,16,18)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271952 (CHEMBL4126465) Show SMILES OC(=O)C(\S)=C\c1c(F)ccc(F)c1F Show InChI InChI=1S/C9H5F3O2S/c10-5-1-2-6(11)8(12)4(5)3-7(15)9(13)14/h1-3,15H,(H,13,14)/b7-3-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50247639 (CHEMBL4068716) Show SMILES CN1CCN(CC1)NC(=O)CN1C(=S)S\C(=C/c2c(Cl)ccc(Cl)c2Cl)C1=O Show InChI InChI=1S/C17H17Cl3N4O2S2/c1-22-4-6-23(7-5-22)21-14(25)9-24-16(26)13(28-17(24)27)8-10-11(18)2-3-12(19)15(10)20/h2-3,8H,4-7,9H2,1H3,(H,21,25)/b13-8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254341 (1-(2-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1Cl)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H20ClN3O4S/c1-12-15(20-17(22)19-14-8-4-3-7-13(14)18)11-16(25-12)26(23,24)21-9-5-2-6-10-21/h3-4,7-8,11H,2,5-6,9-10H2,1H3,(H2,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254343 ((S)-1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-...) Show SMILES C[C@H](NC(=O)Nc1cc(oc1C)S(=O)(=O)N1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C19H25N3O4S/c1-14(16-9-5-3-6-10-16)20-19(23)21-17-13-18(26-15(17)2)27(24,25)22-11-7-4-8-12-22/h3,5-6,9-10,13-14H,4,7-8,11-12H2,1-2H3,(H2,20,21,23)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254435 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C18H17N3O4S/c1-13-16(20-18(22)19-14-8-4-2-5-9-14)12-17(25-13)26(23,24)21-15-10-6-3-7-11-15/h2-12,21H,1H3,(H2,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6110 (4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[2-(morp...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccsc2CN2CCOCC2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H22Cl2N4O2S/c1-33-24-12-23(20(27)11-21(24)28)31-26-17(13-29)14-30-22-10-16(2-3-19(22)26)18-4-9-35-25(18)15-32-5-7-34-8-6-32/h2-4,9-12,14H,5-8,15H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2011-4 (2002) Article DOI: 10.1016/s0960-894x(02)00302-5 BindingDB Entry DOI: 10.7270/Q2PC30KC
					More data for this Ligand-Target Pair
Lipoprotein lipase (Rattus norvegicus)	BDBM50254433 (1-(2-methyl-5-(4-methylpiperazin-1-ylsulfonyl)fura...) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1 Show InChI InChI=1S/C17H22N4O4S/c1-13-15(19-17(22)18-14-6-4-3-5-7-14)12-16(25-13)26(23,24)21-10-8-20(2)9-11-21/h3-7,12H,8-11H2,1-2H3,(H2,18,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Lipoprotein lipase from adipose tissue of rat				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271891 (CHEMBL4129450) Show SMILES CN1CCN(CC1)NC(=O)CN1C(=O)S\C(=C/c2c(Cl)ccc(Cl)c2Cl)C1=O Show InChI InChI=1S/C17H17Cl3N4O3S/c1-22-4-6-23(7-5-22)21-14(25)9-24-16(26)13(28-17(24)27)8-10-11(18)2-3-12(19)15(10)20/h2-3,8H,4-7,9H2,1H3,(H,21,25)/b13-8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271824 (CHEMBL4129233) Show SMILES Cc1ccc(\C=C(/S)C(O)=O)cc1 Show InChI InChI=1S/C10H10O2S/c1-7-2-4-8(5-3-7)6-9(13)10(11)12/h2-6,13H,1H3,(H,11,12)/b9-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271835 (CHEMBL4095898) Show SMILES OC(=O)C(\S)=C\c1ccccc1 Show InChI InChI=1S/C9H8O2S/c10-9(11)8(12)6-7-4-2-1-3-5-7/h1-6,12H,(H,10,11)/b8-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271798 (CHEMBL3221923) Show SMILES OC(=O)C(\S)=C\c1ccccc1Cl Show InChI InChI=1S/C9H7ClO2S/c10-7-4-2-1-3-6(7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271868 (CHEMBL4125695) Show SMILES OC(=O)C(\S)=C\c1cccc(Cl)c1Cl Show InChI InChI=1S/C9H6Cl2O2S/c10-6-3-1-2-5(8(6)11)4-7(14)9(12)13/h1-4,14H,(H,12,13)/b7-4-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50254435 (5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...) Show SMILES Cc1oc(cc1NC(=O)Nc1ccccc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C18H17N3O4S/c1-13-16(20-18(22)19-14-8-4-2-5-9-14)12-17(25-13)26(23,24)21-15-10-6-3-7-11-15/h2-12,21H,1H3,(H2,19,20,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of endothelial lipase (unknown origin)				Bioorg Med Chem Lett 19: 27-30 (2008) Article DOI: 10.1016/j.bmcl.2008.11.033 BindingDB Entry DOI: 10.7270/Q2BP02NZ
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacillus cereus)	BDBM50271867 (CHEMBL4128976) Show SMILES CN1CCN(CC1)NC(=O)CN1C(=S)S\C(=C/c2cccc(Cl)c2Cl)C1=O Show InChI InChI=1S/C17H18Cl2N4O2S2/c1-21-5-7-22(8-6-21)20-14(24)10-23-16(25)13(27-17(23)26)9-11-3-2-4-12(18)15(11)19/h2-4,9H,5-8,10H2,1H3,(H,20,24)/b13-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay				Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC
					More data for this Ligand-Target Pair

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