Compile Data Set for Download or QSAR

Found 81 hits with Last Name = 'winssinger' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557999 (CHEMBL4786214) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(N)=O |t:5| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557998 (CHEMBL4796866) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:5| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557984 (CHEMBL4744734) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557985 (CHEMBL4759705) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557997 (CHEMBL4786563) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1ccccc1NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(N)=O |t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557996 (CHEMBL4778692) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1ccccc1NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557995 (CHEMBL4800222) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557994 (CHEMBL4793855) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557988 (CHEMBL4786891) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1(CC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557989 (CHEMBL4779255) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1(CC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557987 (CHEMBL4777832) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)CC1(CCCCC1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(N)=O |t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557986 (CHEMBL4746426) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)CC1(CCCCC1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557981 (CHEMBL4796812) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)COCCOCCNC(=O)C(C1CC1)n1cc(nn1)-c1cccc(OC)c1)C(N)=O |t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557980 (CHEMBL4741877) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)COCCOCCNC(=O)C(C1CC1)n1cc(nn1)-c1cccc(OC)c1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557983 (CHEMBL4793211) Show SMILES NC(=O)C(CNC(=O)CCCCCNC1=NS(=O)(=O)c2ccccc12)NC(=O)Cc1ccc(CNC(=O)[C@H](C2CC2)n2cc(CC3CCCCC3)nn2)cc1 |r,t:14| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557982 (CHEMBL4762824) Show SMILES NC(=O)C(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)NC(=O)C(CNC(=O)CCCCCNC1=NS(=O)(=O)c2ccccc12)NC(=O)Cc1ccc(CNC(=O)[C@H](C2CC2)n2cc(CC3CCCCC3)nn2)cc1 |r,t:40| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557990 (CHEMBL4752726) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557991 (CHEMBL4754600) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557985 (CHEMBL4759705) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557984 (CHEMBL4744734) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557992 (CHEMBL4762078) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:5| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557993 (CHEMBL4740579) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:5| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557992 (CHEMBL4762078) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:5| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557993 (CHEMBL4740579) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:5| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557983 (CHEMBL4793211) Show SMILES NC(=O)C(CNC(=O)CCCCCNC1=NS(=O)(=O)c2ccccc12)NC(=O)Cc1ccc(CNC(=O)[C@H](C2CC2)n2cc(CC3CCCCC3)nn2)cc1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557982 (CHEMBL4762824) Show SMILES NC(=O)C(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)NC(=O)C(CNC(=O)CCCCCNC1=NS(=O)(=O)c2ccccc12)NC(=O)Cc1ccc(CNC(=O)[C@H](C2CC2)n2cc(CC3CCCCC3)nn2)cc1 |r,t:40| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557980 (CHEMBL4741877) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)COCCOCCNC(=O)C(C1CC1)n1cc(nn1)-c1cccc(OC)c1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557981 (CHEMBL4796812) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)COCCOCCNC(=O)C(C1CC1)n1cc(nn1)-c1cccc(OC)c1)C(N)=O |t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557988 (CHEMBL4786891) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1(CC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557989 (CHEMBL4779255) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1(CC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557990 (CHEMBL4752726) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557991 (CHEMBL4754600) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)C1CCCC(C1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557987 (CHEMBL4777832) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)CC1(CCCCC1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(N)=O |t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50557986 (CHEMBL4746426) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)CC1(CCCCC1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557998 (CHEMBL4796866) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:5| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557999 (CHEMBL4786214) Show SMILES CC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(N)=O |t:5| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557997 (CHEMBL4786563) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1ccccc1NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(N)=O |t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557996 (CHEMBL4778692) Show SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)c1ccccc1NC(=O)c1n[nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557995 (CHEMBL4800222) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50557994 (CHEMBL4793855) Show SMILES CCC(C)C(NC1=NS(=O)(=O)c2ccccc12)C(=O)NC[C@@H](NC(=O)CC1(CCCCC1)NC(=O)[C@H](CC(C)(C)C)n1cc(CC2CCCCC2)nn1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12)C(N)=O |r,t:6| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...				Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.102 BindingDB Entry DOI: 10.7270/Q2KK9GHP
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50341234 (4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)py...) Show SMILES Cc1ccc(NC(=O)c2ccc(CCl)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C24H20ClN5O/c1-16-4-9-20(28-23(31)18-7-5-17(14-25)6-8-18)13-22(16)30-24-27-12-10-21(29-24)19-3-2-11-26-15-19/h2-13,15H,14H2,1H3,(H,28,31)(H,27,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into polyAlaGluLsTyr after 60 mins by microplate scintillation count...				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into polyAlaGluLsTyr after 60 mins by microplate scintillation count...				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50341234 (4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)py...) Show SMILES Cc1ccc(NC(=O)c2ccc(CCl)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C24H20ClN5O/c1-16-4-9-20(28-23(31)18-7-5-17(14-25)6-8-18)13-22(16)30-24-27-12-10-21(29-24)19-3-2-11-26-15-19/h2-13,15H,14H2,1H3,(H,28,31)(H,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation counting				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation counting				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50341235 (4-(aminomethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyr...) Show SMILES Cc1ccc(NC(=O)c2ccc(CN)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C24H22N6O/c1-16-4-9-20(28-23(31)18-7-5-17(14-25)6-8-18)13-22(16)30-24-27-12-10-21(29-24)19-3-2-11-26-15-19/h2-13,15H,14,25H2,1H3,(H,28,31)(H,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	788	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation counting				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50341236 (4-((2-chloroacetamido)methyl)-N-(4-methyl-3-(4-(py...) Show SMILES Cc1ccc(NC(=O)c2ccc(CNC(=O)CCl)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C26H23ClN6O2/c1-17-4-9-21(31-25(35)19-7-5-18(6-8-19)15-30-24(34)14-27)13-23(17)33-26-29-12-10-22(32-26)20-3-2-11-28-16-20/h2-13,16H,14-15H2,1H3,(H,30,34)(H,31,35)(H,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	788	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation counting				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50341236 (4-((2-chloroacetamido)methyl)-N-(4-methyl-3-(4-(py...) Show SMILES Cc1ccc(NC(=O)c2ccc(CNC(=O)CCl)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C26H23ClN6O2/c1-17-4-9-21(31-25(35)19-7-5-18(6-8-19)15-30-24(34)14-27)13-23(17)33-26-29-12-10-22(32-26)20-3-2-11-28-16-20/h2-13,16H,14-15H2,1H3,(H,30,34)(H,31,35)(H,29,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into polyAlaGluLsTyr after 60 mins by microplate scintillation count...				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50341235 (4-(aminomethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyr...) Show SMILES Cc1ccc(NC(=O)c2ccc(CN)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C24H22N6O/c1-16-4-9-20(28-23(31)18-7-5-17(14-25)6-8-18)13-22(16)30-24-27-12-10-21(29-24)19-3-2-11-26-15-19/h2-13,15H,14,25H2,1H3,(H,28,31)(H,27,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into polyAlaGluLsTyr after 60 mins by microplate scintillation count...				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into polyAlaGluLsTyr after 60 mins by microplate scintillation counting				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50341238 (4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...) Show SMILES CC(=C)C(=O)NCc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C28H26N6O2/c1-18(2)26(35)31-16-20-7-9-21(10-8-20)27(36)32-23-11-6-19(3)25(15-23)34-28-30-14-12-24(33-28)22-5-4-13-29-17-22/h4-15,17H,1,16H2,2-3H3,(H,31,35)(H,32,36)(H,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation counting				J Med Chem 54: 1347-55 (2011) Article DOI: 10.1021/jm101396q BindingDB Entry DOI: 10.7270/Q2NC61J5
					More data for this Ligand-Target Pair

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