Compile Data Set for Download or QSAR

Found 84 hits with Last Name = 'wong' and Initial = 'jk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (RAT)	BDBM22868 (11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-b...) Show SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM35938 (1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...) Show SMILES CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1 Show InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM35938 (1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...) Show SMILES CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1 Show InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50063449 (8-Chloro-11-piperazin-1-yl-6,11-dihydro-5H-benzo[5...) Show SMILES Clc1ccc2C(N3CCNCC3)c3ncccc3CCc2c1 Show InChI InChI=1S/C18H20ClN3/c19-15-5-6-16-14(12-15)4-3-13-2-1-7-21-17(13)18(16)22-10-8-20-9-11-22/h1-2,5-7,12,18,20H,3-4,8-11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073184 (8-Chloro-11-(4-methyl-piperazin-1-yl)-6,11-dihydro...) Show SMILES CN1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12 Show InChI InChI=1S/C19H22ClN3/c1-22-9-11-23(12-10-22)19-17-7-6-16(20)13-15(17)5-4-14-3-2-8-21-18(14)19/h2-3,6-8,13,19H,4-5,9-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281832 (1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(Br)cnc-12 Show InChI InChI=1S/C21H20BrClN2O/c1-13(26)25-8-6-14(7-9-25)20-19-5-4-18(23)11-15(19)2-3-16-10-17(22)12-24-21(16)20/h4-5,10-12H,2-3,6-9H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50061467 (1-[4-(8-Chloro-3-hydroxymethyl-5,6-dihydro-benzo[5...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(-[#6]-[#8])cnc-12 Show InChI InChI=1S/C22H23ClN2O2/c1-14(27)25-8-6-16(7-9-25)21-20-5-4-19(23)11-17(20)2-3-18-10-15(13-26)12-24-22(18)21/h4-5,10-12,26H,2-3,6-9,13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007464 (4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b...) Show SMILES Clc1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6]=O)c1 Show InChI InChI=1S/C20H19ClN2O/c21-17-5-6-18-16(12-17)4-3-15-2-1-9-22-20(15)19(18)14-7-10-23(13-24)11-8-14/h1-2,5-6,9,12-13H,3-4,7-8,10-11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281836 (1-{4-[8-Chloro-3-(1-hydroxy-ethyl)-5,6-dihydro-ben...) Show SMILES [#6]-[#6](-[#8])-c1cnc2c(-[#6]-[#6]-c3cc(Cl)ccc3\[#6]-2=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](-[#6])=O)c1 Show InChI InChI=1S/C23H25ClN2O2/c1-14(27)19-11-18-4-3-17-12-20(24)5-6-21(17)22(23(18)25-13-19)16-7-9-26(10-8-16)15(2)28/h5-6,11-14,27H,3-4,7-10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007461 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C22H23ClN2O/c1-2-20(26)25-12-9-15(10-13-25)21-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-22(16)21/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073186 (4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1...) Show SMILES CN1CCN(CC1=O)C1c2ccc(Cl)cc2CCc2cccnc12 Show InChI InChI=1S/C19H20ClN3O/c1-22-9-10-23(12-17(22)24)19-16-7-6-15(20)11-14(16)5-4-13-3-2-8-21-18(13)19/h2-3,6-8,11,19H,4-5,9-10,12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007465 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C23H25ClN2O/c1-2-4-21(27)26-13-10-16(11-14-26)22-20-9-8-19(24)15-18(20)7-6-17-5-3-12-25-23(17)22/h3,5,8-9,12,15H,2,4,6-7,10-11,13-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281829 (1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cycl...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(-[#6])cnc-12 Show InChI InChI=1S/C22H23ClN2O/c1-14-11-18-4-3-17-12-19(23)5-6-20(17)21(22(18)24-13-14)16-7-9-25(10-8-16)15(2)26/h5-6,11-13H,3-4,7-10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007454 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]C([#6])([#6])[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C24H27ClN2O/c1-24(2,3)23(28)27-13-10-16(11-14-27)21-20-9-8-19(25)15-18(20)7-6-17-5-4-12-26-22(17)21/h4-5,8-9,12,15H,6-7,10-11,13-14H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281834 (1-[4-(3,8-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(Cl)cnc-12 Show InChI InChI=1S/C21H20Cl2N2O/c1-13(26)25-8-6-14(7-9-25)20-19-5-4-17(22)10-15(19)2-3-16-11-18(23)12-24-21(16)20/h4-5,10-12H,2-3,6-9H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073172 (4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1...) Show SMILES Clc1ccc2C(N3CCNC(=O)C3)c3ncccc3CCc2c1 Show InChI InChI=1S/C18H18ClN3O/c19-14-5-6-15-13(10-14)4-3-12-2-1-7-21-17(12)18(15)22-9-8-20-16(23)11-22/h1-2,5-7,10,18H,3-4,8-9,11H2,(H,20,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007466 (CHEMBL140924 | [4-(8-Chloro-5,6-dihydro-benzo[5,6]...) Show SMILES Clc1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-c2ccccc2)c1 Show InChI InChI=1S/C26H23ClN2O/c27-22-10-11-23-21(17-22)9-8-19-7-4-14-28-25(19)24(23)18-12-15-29(16-13-18)26(30)20-5-2-1-3-6-20/h1-7,10-11,14,17H,8-9,12-13,15-16H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007470 (1-[4-(8-Methyl-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(-[#6])cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C22H24N2O/c1-15-5-8-20-19(14-15)7-6-18-4-3-11-23-22(18)21(20)17-9-12-24(13-10-17)16(2)25/h3-5,8,11,14H,6-7,9-10,12-13H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281835 (1-[4-(8-Chloro-3-methylsulfanyl-5,6-dihydro-benzo[...) Show SMILES [#6]-[#16]-c1cnc2c(-[#6]-[#6]-c3cc(Cl)ccc3\[#6]-2=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](-[#6])=O)c1 Show InChI InChI=1S/C22H23ClN2OS/c1-14(26)25-9-7-15(8-10-25)21-20-6-5-18(23)11-16(20)3-4-17-12-19(27-2)13-24-22(17)21/h5-6,11-13H,3-4,7-10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281840 (1-[4-(8-Chloro-3-phenyl-5,6-dihydro-benzo[5,6]cycl...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(cnc-12)-c1ccccc1 Show InChI InChI=1S/C27H25ClN2O/c1-18(31)30-13-11-20(12-14-30)26-25-10-9-24(28)16-21(25)7-8-22-15-23(17-29-27(22)26)19-5-3-2-4-6-19/h2-6,9-10,15-17H,7-8,11-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281841 (1-[4-(8-Chloro-4-methyl-5,6-dihydro-benzo[5,6]cycl...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2c(-[#6])ccnc-12 Show InChI InChI=1S/C22H23ClN2O/c1-14-7-10-24-22-19(14)5-3-17-13-18(23)4-6-20(17)21(22)16-8-11-25(12-9-16)15(2)26/h4,6-7,10,13H,3,5,8-9,11-12H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281830 (1-[4-(4,8-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2c(Cl)ccnc-12 Show InChI InChI=1S/C21H20Cl2N2O/c1-13(26)25-10-7-14(8-11-25)20-17-5-3-16(22)12-15(17)2-4-18-19(23)6-9-24-21(18)20/h3,5-6,9,12H,2,4,7-8,10-11H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073180 (4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1...) Show SMILES Clc1ccc2C(N3CCN(CC3)C=O)c3ncccc3CCc2c1 Show InChI InChI=1S/C19H20ClN3O/c20-16-5-6-17-15(12-16)4-3-14-2-1-7-21-18(14)19(17)23-10-8-22(13-24)9-11-23/h1-2,5-7,12-13,19H,3-4,8-11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007463 (CHEMBL124466 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...) Show SMILES CN(CC\C=C1/c2ccc(Cl)cc2CCc2cccnc12)C(C)=O Show InChI InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007473 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007473 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007473 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM22876 (CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...) Show SMILES [#6]-[#6]-[#8]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281825 (1-[4-(8-Chloro-3-methoxy-5,6-dihydro-benzo[5,6]cyc...) Show SMILES [#6]-[#8]-c1cnc2c(-[#6]-[#6]-c3cc(Cl)ccc3\[#6]-2=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](-[#6])=O)c1 Show InChI InChI=1S/C22H23ClN2O2/c1-14(26)25-9-7-15(8-10-25)21-20-6-5-18(23)11-16(20)3-4-17-12-19(27-2)13-24-22(17)21/h5-6,11-13H,3-4,7-10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281842 (11-(1-Acetyl-piperidin-4-ylidene)-8-chloro-6,11-di...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(-[#6]=O)cnc-12 Show InChI InChI=1S/C22H21ClN2O2/c1-14(27)25-8-6-16(7-9-25)21-20-5-4-19(23)11-17(20)2-3-18-10-15(13-26)12-24-22(18)21/h4-5,10-13H,2-3,6-9H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007462 (1-[4-(8-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(F)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007474 (CHEMBL141432 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...) Show SMILES CN(CC\C=C1\c2ccc(Cl)cc2CCc2cccnc12)C(C)=O Show InChI InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073176 (1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...) Show SMILES CC(=O)N1CCCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12 Show InChI InChI=1S/C21H24ClN3O/c1-15(26)24-10-3-11-25(13-12-24)21-19-8-7-18(22)14-17(19)6-5-16-4-2-9-23-20(16)21/h2,4,7-9,14,21H,3,5-6,10-13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281837 (1-[4-(8-Chloro-2-methyl-5,6-dihydro-benzo[5,6]cycl...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2ccc(-[#6])nc-12 Show InChI InChI=1S/C22H23ClN2O/c1-14-3-4-17-5-6-18-13-19(23)7-8-20(18)21(22(17)24-14)16-9-11-25(12-10-16)15(2)26/h3-4,7-8,13H,5-6,9-12H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281827 (1-[4-(3-Acetyl-8-chloro-5,6-dihydro-benzo[5,6]cycl...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccc(Cl)cc2-[#6]-[#6]-c2cc(cnc-12)-[#6](-[#6])=O Show InChI InChI=1S/C23H23ClN2O2/c1-14(27)19-11-18-4-3-17-12-20(24)5-6-21(17)22(23(18)25-13-19)16-7-9-26(10-8-16)15(2)28/h5-6,11-13H,3-4,7-10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007472 (1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES CC(=O)C1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12 |(9.33,-15.2,;8.01,-14.43,;6.66,-15.18,;8.01,-12.89,;9.36,-12.16,;9.4,-10.62,;8.08,-9.84,;6.75,-10.57,;6.72,-12.09,;8.11,-8.3,;9.61,-7.63,;10.74,-8.72,;12.26,-8.29,;12.61,-6.76,;14.11,-6.34,;11.48,-5.67,;9.99,-6.12,;9.09,-5.01,;7.55,-5.01,;6.47,-6.11,;5.02,-5.62,;3.89,-6.62,;4.18,-8.13,;5.62,-8.62,;6.78,-7.62,)| Show InChI InChI=1S/C22H22ClNO/c1-14(25)15-4-6-16(7-5-15)21-20-11-10-19(23)13-18(20)9-8-17-3-2-12-24-22(17)21/h2-3,10-13,15H,4-9H2,1H3/b21-16-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281839 (1-[4-(2,8-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2ccc(Cl)nc-12 Show InChI InChI=1S/C21H20Cl2N2O/c1-13(26)25-10-8-14(9-11-25)20-18-6-5-17(22)12-16(18)3-2-15-4-7-19(23)24-21(15)20/h4-7,12H,2-3,8-11H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007460 (1-[4-(9-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2cc(Cl)ccc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50281838 (1-[4-(8-Chloro-3-hydroxy-5,6-dihydro-benzo[5,6]cyc...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(-[#8])cnc-12 Show InChI InChI=1S/C21H21ClN2O2/c1-13(25)24-8-6-14(7-9-24)20-19-5-4-17(22)10-15(19)2-3-16-11-18(26)12-23-21(16)20/h4-5,10-12,26H,2-3,6-9H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.				Bioorg Med Chem Lett 3: 1073-1078 (1993) Article DOI: 10.1016/S0960-894X(00)80290-5 BindingDB Entry DOI: 10.7270/Q2445MDZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007456 (1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1...) Show SMILES [#6]-[#8]-c1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](-[#6])=O)c1 Show InChI InChI=1S/C22H24N2O2/c1-15(25)24-12-9-16(10-13-24)21-20-8-7-19(26-2)14-18(20)6-5-17-4-3-11-23-22(17)21/h3-4,7-8,11,14H,5-6,9-10,12-13H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007467 (1-[4-(5,6-Dihydro-benzo[5,6]cyclohepta[1,2-b]pyrid...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H22N2O/c1-15(24)23-13-10-17(11-14-23)20-19-7-3-2-5-16(19)8-9-18-6-4-12-22-21(18)20/h2-7,12H,8-11,13-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073182 (1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...) Show SMILES CCC(=O)N1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12 Show InChI InChI=1S/C21H24ClN3O/c1-2-19(26)24-10-12-25(13-11-24)21-18-8-7-17(22)14-16(18)6-5-15-4-3-9-23-20(15)21/h3-4,7-9,14,21H,2,5-6,10-13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007458 (1-[4-(9-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2cc(F)ccc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50007459 (1-[4-(8,9-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2cc(Cl)c(Cl)cc2-[#6]-[#6]-c2cccnc-12 Show InChI InChI=1S/C21H20Cl2N2O/c1-13(26)25-9-6-14(7-10-25)20-17-12-19(23)18(22)11-16(17)5-4-15-3-2-8-24-21(15)20/h2-3,8,11-12H,4-7,9-10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073175 (1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...) Show SMILES CCCC(=O)N1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12 Show InChI InChI=1S/C22H26ClN3O/c1-2-4-20(27)25-11-13-26(14-12-25)22-19-9-8-18(23)15-17(19)7-6-16-5-3-10-24-21(16)22/h3,5,8-10,15,22H,2,4,6-7,11-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50403681 (CHEMBL2111767) Show SMILES CC(=O)N1CCN(CC1)[C@@H]1c2ccc(Cl)cc2CCc2cccnc12 |r| Show InChI InChI=1S/C20H22ClN3O/c1-14(25)23-9-11-24(12-10-23)20-18-7-6-17(21)13-16(18)5-4-15-3-2-8-22-19(15)20/h2-3,6-8,13,20H,4-5,9-12H2,1H3/t20-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073185 (2-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1...) Show SMILES Clc1ccc2C(N3CCN4C(CCC4=O)C3)c3ncccc3CCc2c1 Show InChI InChI=1S/C21H22ClN3O/c22-16-5-7-18-15(12-16)4-3-14-2-1-9-23-20(14)21(18)24-10-11-25-17(13-24)6-8-19(25)26/h1-2,5,7,9,12,17,21H,3-4,6,8,10-11,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073181 (1-[4-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-y...) Show SMILES CC(=O)N1CCN(CC1)C1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C21H24N2O/c1-16(24)22-12-14-23(15-13-22)21-19-8-4-2-6-17(19)10-11-18-7-3-5-9-20(18)21/h2-9,21H,10-15H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50406423 (CHEMBL334318) Show SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]-[#6]-c2ccccc-12 Show InChI InChI=1S/C22H23NO/c1-16(24)23-14-12-19(13-15-23)22-20-8-4-2-6-17(20)10-11-18-7-3-5-9-21(18)22/h2-9H,10-15H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50073173 (1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...) Show SMILES CC(=O)N1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12 Show InChI InChI=1S/C20H22ClN3O/c1-14(25)23-9-11-24(12-10-23)20-18-7-6-17(21)13-16(18)5-4-15-3-2-8-22-19(15)20/h2-3,6-8,13,20H,4-5,9-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes				Bioorg Med Chem Lett 8: 3469-74 (1999) BindingDB Entry DOI: 10.7270/Q21J98X8
					More data for this Ligand-Target Pair

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