BindingDB PrimarySearch

Found 1044 hits with Last Name = 'wroblewski' and Initial = 'jt'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50181745 (3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile \| CH...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain membranes				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181745 (3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile \| CH...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cells				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50181753 (3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine ...) Show SMILES Cc1nc(cs1)C#Cc1cncc(C=C)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain membranes				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143073 ((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181753 (3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine ...) Show SMILES Cc1nc(cs1)C#Cc1cncc(C=C)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cells				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid \| 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160633 (2-methyl-6-[(5-phenylpyridin-3-yl)ethynyl]pyridine...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143074 ((S)-2-[3-((S)-Carboxy-phenyl-methyl)-ureido]-penta...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143078 ((S)-2-{3-[(S)-1-Carboxy-2-(4-hydroxy-phenyl)-ethyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143070 ((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143080 ((S)-2-{3-[(S)-Carboxy-(4-hydroxy-phenyl)-methyl]-u...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160627 (2-{[5-(2-furyl)pyridin-3-yl]ethynyl}-6-methylpyrid...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)-c1ccco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50102258 ((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143069 ((S)-2-[3-((S)-1-Carboxy-2-phenyl-ethyl)-ureido]-pe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160624 (6-Methyl-5''-(6-methyl-pyridin-2-ylethynyl)-[2,3''...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)-c1cccc(C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143066 ((2S,5S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-urei...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143068 ((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160640 (2-(3-Furan-2-yl-phenylethynyl)-6-methyl-pyridine \|...) Show SMILES Cc1cccc(n1)C#Cc1cccc(c1)-c1ccco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160631 (2-{[5-(3-methoxyphenyl)pyridin-3-yl]ethynyl}-6-met...) Show SMILES COc1cccc(c1)-c1cncc(c1)C#Cc1cccc(C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143064 ((2S,5R)-2-Benzyl-4-[3-((S)-3-carboxy-1-carboxy-pro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	95.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160622 (2-Methyl-6-(3-thiophen-2-yl-phenylethynyl)-pyridin...) Show SMILES Cc1cccc(n1)C#Cc1cccc(c1)-c1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	147	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160623 (2-methyl-6-[(5-thien-2-ylpyridin-3-yl)ethynyl]pyri...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)-c1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143077 ((S)-2-{3-[(S)-3-Carboxy-1-(1H-tetrazol-5-yl)-propy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	335	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143075 ((2S,5R)-2-[3-((S)-3-Carboxy-1-carboxy-4-phenyl-but...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	392	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50004051 (2-Amino-4-phosphono-butyric acid \| 2-Amino-4-phosp...) Show SMILES NC(CCP(O)(O)=O)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50004051 (2-Amino-4-phosphono-butyric acid \| 2-Amino-4-phosp...) Show SMILES NC(CCP(O)(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143072 ((S)-2-[3-((S)-1,3-Dicarboxy-1-methyl-propyl)-ureid...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	939	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160621 (2-Biphenyl-3-ylethynyl-6-methyl-pyridine \| CHEMBL1...) Show SMILES Cc1cccc(n1)C#Cc1cccc(c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	993	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50398813 (CHEMBL2114987) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50004051 (2-Amino-4-phosphono-butyric acid \| 2-Amino-4-phosp...) Show SMILES NC(CCP(O)(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50398814 (CHEMBL2115435) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160630 (2-(3''-Methoxy-biphenyl-3-ylethynyl)-6-methyl-pyri...) Show SMILES COc1cccc(c1)-c1cccc(c1)C#Cc1cccc(C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143067 ((S)-2-(3-{(S)-3-Carboxy-1-[1-(2-cyano-ethyl)-1H-te...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM86199 (CAS_595 \| CAS_67678 \| D-cystine \| L-cystine \| NSC_...) Show SMILES NC(CSSCC(N)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143065 ((S)-4-{3-[(S)-3-Carboxy-1-(1H-tetrazol-5-yl)-propy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
N-acetylated-alpha-linked acidic dipeptidase 2 (Homo sapiens (Human))	BDBM50143079 ((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM86201 (L-homocysteine sulfinic acid) Show SMILES N[C@@H](CCS(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM86201 (L-homocysteine sulfinic acid) Show SMILES N[C@@H](CCS(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	6.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50220147 ((S)-2-amino-4-sulfobutanoic acid \| CHEMBL230951 \| ...) Show SMILES N[C@@H](CCS(O)(=O)=O)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50220147 ((S)-2-amino-4-sulfobutanoic acid \| CHEMBL230951 \| ...) Show SMILES N[C@@H](CCS(O)(=O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86196 (D-homocysteic acid) Show SMILES N[C@H](CCS(O)(=O)=O)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86197 (D-homocysteine sulfinic acid) Show SMILES N[C@H](CCS(O)=O)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86205 (D-homocysteine thiolactone) Show SMILES N[C@@H]1CCSC1=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86195 (CAS_6137 \| CAS_84815 \| D-methionine \| L-methionine...) Show SMILES CSCCC(N)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86202 (CAS_778 \| DL-homocysteine \| NSC_778) Show SMILES NC(CCS)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM85473 (L-Cysteic acid, 8 \| L-cysteic acid) Show SMILES NC(CS(O)(=O)=O)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86203 (CAS_5862 \| L-cysteine \| NSC_5862) Show SMILES NC(CS)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM86199 (CAS_595 \| CAS_67678 \| D-cystine \| L-cystine \| NSC_...) Show SMILES NC(CSSCC(N)C(O)=O)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 131-42 (2003) Article DOI: 10.1124/jpet.102.047092 BindingDB Entry DOI: 10.7270/Q2VT1QN7
					More data for this Ligand-Target Pair

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