Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090529 (2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090516 (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090517 (5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090519 (CHEMBL300519 | [2-(5-Isopropyl-1H-indol-3-yl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090523 (2-(5-tert-Butyl-1-methyl-1H-indol-3-yl)-ethylamine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090527 (1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090527 (1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50060429 ((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090522 (5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50098549 ((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090530 (6-(1,2,3,5,8,8a-Hexahydro-indolizin-7-yl)-1-(napht...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28583 (5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136466 (CHEMBL343492 | Dimethyl-[2-(6-pyridin-3-yl-indol-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090533 (2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136469 (4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116963 (2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090521 (5-tert-Butyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090532 (2-[1-(Naphthalene-2-sulfonyl)-1H-indol-6-yl]-octah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116967 (2-[2-(6-Bromo-indol-1-yl)-ethyl]-decahydro-pyrido[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090536 (2-[1-(Toluene-4-sulfonyl)-1H-indol-6-yl]-octahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136462 (4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090515 (5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090535 (2-[1-(2,4-Difluoro-benzenesulfonyl)-1H-indol-6-yl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136465 (CHEMBL343105 | Dimethyl-{2-[6-(tetrahydro-pyran-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136471 ((S)-1-{2-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090531 (7-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090534 (2-[1-(Toluene-4-sulfonyl)-1H-indol-6-yl]-octahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090518 (5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136464 (CHEMBL138873 | Dimethyl-{2-[6-(tetrahydro-thiopyra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090526 (2-(1-Benzenesulfonyl-1H-indol-6-yl)-octahydro-pyri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116960 (2-[2-(6-Trifluoromethyl-indol-1-yl)-ethyl]-decahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136468 (CHEMBL138821 | Dimethyl-[2-(6-thiophen-3-yl-indol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116971 (6-Bromo-1-[2-(4-cyclopropylmethyl-[1,4]diazepan-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50090517 (5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116970 (6-Bromo-1-[2-(4-cyclopentyl-[1,4]diazepan-1-yl)-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116951 (2-[2-(6-Chloro-indol-1-yl)-ethyl]-decahydro-pyrido...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50090524 (4-Amino-N-(2,6-bis-methylamino-pyridin-4-yl)-benze...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50090519 (CHEMBL300519 | [2-(5-Isopropyl-1H-indol-3-yl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116943 (6-Bromo-1-[2-(4-isopropyl-[1,4]diazepan-1-yl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50090516 (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50049099 (CHEMBL50492 | [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116964 (6-Bromo-1-[2-(4-cyclopropyl-[1,4]diazepan-1-yl)-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116944 (6-Bromo-1-[2-(4-cyclohexyl-[1,4]diazepan-1-yl)-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50395922 (CHEMBL2164552) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [3H]AZD9272 from human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter | Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50136467 (CHEMBL343712 | {2-[6-(3,6-Dihydro-2H-thiopyran-4-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells) | Bioorg Med Chem Lett 13: 4409-13 (2003) BindingDB Entry DOI: 10.7270/Q2HT2NR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116966 (1-[2-(4-Methyl-[1,4]diazepan-1-yl)-ethyl]-6-triflu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50395922 (CHEMBL2164552) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [3H]MPEP from human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter | Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50116958 (6-Bromo-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSD | Bioorg Med Chem Lett 12: 2451-4 (2002) BindingDB Entry DOI: 10.7270/Q25T3JTZ | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 767 total ) | Next | Last >> |