BindingDB PrimarySearch

Found 1398 hits with Last Name = 'xue' and Initial = 'l'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174361 (CHEMBL370606 \| L-888607 \| [(S)-9-(4-Chloro-phenyls...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	CHEMBL5291138 Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL CHEMBL PC cid PC sid UniChem Similars		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mean functional activity against human H3 receptor				Citation and Details
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174354 (CHEMBL373294 \| [1-(2,5-Dichloro-benzenesulfonyl)-5...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174357 (CHEMBL199040 \| [1-(4-Chloro-benzenesulfonyl)-5-flu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346870 (CHEMBL1797647) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)				Citation and Details
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity (agonistic) towards human CRTH2 receptor expressed in CHO cells; range 15 to 25 nM				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	BDBM50346870 (CHEMBL1797647) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mean functional activity against human H3 receptor				Citation and Details
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174351 (CHEMBL196707 \| [5-Fluoro-1-(4-methanesulfonyl-benz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Cocaine esterase (Homo sapiens (Human))	BDBM50552232 (CHEMBL4776624) Show SMILES Show InChI	NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112856 BindingDB Entry DOI: 10.7270/Q2NZ8CB7
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174352 (CHEMBL370257 \| [5-Fluoro-1-(4-fluoro-benzenesulfon...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	BDBM50586363 (CHEMBL5079374) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)				Citation and Details
TBA					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	CHEMBL5281080 Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL CHEMBL PC cid PC sid UniChem Similars		157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mean functional activity against human H3 receptor				Citation and Details
TBA					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	CHEMBL1255711 Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL CHEMBL PC cid PC sid UniChem Similars		193	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mean functional activity against human H3 receptor				Citation and Details
TBA					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	CHEMBL5287743 Show SMILES Cc1cc(NC(=O)Nc2ccc3sccc3c2)sn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL CHEMBL PC cid PC sid UniChem		210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)				Citation and Details
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151161 (5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174353 (CHEMBL196617 \| [5-Fluoro-1-(3-fluoro-benzenesulfon...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174358 ((1-Benzenesulfonyl-5-fluoro-2-methyl-1H-indol-3-yl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151159 (5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174360 (CHEMBL364299 \| [5-Fluoro-1-(4-methoxy-benzenesulfo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	299	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50568522 (CHEMBL4864352) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174356 (CHEMBL193753 \| [5-Fluoro-2-methyl-1-(toluene-4-sul...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	457	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50181669 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ChemBridge Research Laboratories and ChemBridge Corporation Curated by ChEMBL					Assay Description Inhibitory activity against ALK				J Med Chem 49: 1006-15 (2006) Article DOI: 10.1021/jm050824x BindingDB Entry DOI: 10.7270/Q2H994T6
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 \| US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50568521 (CHEMBL4878787) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346585 (CHEMBL1795980 \| S2101) Show SMILES NC1CC1c1cc(F)cc(F)c1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174359 (CHEMBL194918 \| [1-(Butane-1-sulfonyl)-5-fluoro-2-m...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	634	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151163 (5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346585 (CHEMBL1795980 \| S2101) Show SMILES NC1CC1c1cc(F)cc(F)c1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151168 (5-Phenyl-1H-pyrrole-2-carboxylic acid (cyclohexylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50181675 (5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ChemBridge Research Laboratories and ChemBridge Corporation Curated by ChEMBL					Assay Description Inhibitory activity against ALK				J Med Chem 49: 1006-15 (2006) Article DOI: 10.1021/jm050824x BindingDB Entry DOI: 10.7270/Q2H994T6
					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	BDBM50346863 (CHEMBL1797640 \| US8765820, 5b) Show SMILES NC1CC1c1ccc(NC(=O)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151160 (5-Phenyl-1H-pyrrole-2-carboxylic acid (3-diethylam...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151169 (5-Phenyl-1H-pyrrole-2-carboxylic acid [1-cyclohexy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151158 (5-Phenyl-1H-pyrrole-2-carboxylic acid (1-tert-buty...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50346864 (CHEMBL1797641 \| CHEMBL3104337 \| US8765820, 8) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151167 (5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	BDBM50346864 (CHEMBL1797641 \| CHEMBL3104337 \| US8765820, 8) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151164 (5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151157 (5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cocaine esterase (Homo sapiens (Human))	BDBM50017698 (4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...) Show SMILES Show InChI	NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CES2A using 4-methylumbelliferone as a substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112856 BindingDB Entry DOI: 10.7270/Q2NZ8CB7
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50158869 (CHEMBL3786182 \| US10836743, Compound GSK-2879552 \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4(diMe) peptide as substrate measured after 60 mins by amplex red dye based HRP-coupled assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50174354 (CHEMBL373294 \| [1-(2,5-Dichloro-benzenesulfonyl)-5...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human DP receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
REST corepressor 1 (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 \| US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151165 (5-Phenyl-1H-pyrrole-2-carboxylic acid (1-cyclohexy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151170 (CHEMBL185887 \| N-[Cyclohexylcarbamoyl-(4-fluoro-ph...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	CHEMBL5274037 Show SMILES Cc1cc(NC(=O)Nc2ccc3sccc3c2)on1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL CHEMBL PC cid PC sid UniChem		2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mean functional activity against human H3 receptor				Citation and Details
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50346863 (CHEMBL1797640 \| US8765820, 5b) Show SMILES NC1CC1c1ccc(NC(=O)c2ccccc2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346866 (CHEMBL1797643 \| S1201) Show SMILES NC1CC1c1cccc(F)c1OCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50151166 (5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylc...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
Institute for Life Science Research Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50174355 (CHEMBL194019 \| [1-(1,2-Dimethyl-1H-imidazole-4-sul...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oxagen Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human CRTH2 receptor expressed in CHO cells				J Med Chem 48: 6174-7 (2005) Article DOI: 10.1021/jm050519b BindingDB Entry DOI: 10.7270/Q2KK9B9B
Oxagen Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1398 total ) | Next | Last >>