Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 4 (RAT) | BDBM85027 (1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 0.000400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM85027 (1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 0.000480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM85027 (1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 0.000580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM85027 (1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 0.000630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem Patents | Article PubMed | 0.000870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MCE PC cid PC sid UniChem Patents | Article PubMed | 0.000910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM85026 (N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.00560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MCE PC cid PC sid UniChem Patents | Article PubMed | 0.00890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM85026 (N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320811 ((R)- or (S)-1-(1-(4-(1,1-Difluoroethyl)-3- fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320710 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3-fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (Homo sapiens (Human)) | BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem Patents | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320946 ((R)- or (S)-1- (Cyclopropyl(4-(1,1- difluoroethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320813 ((R)- or (S)-1-(1-(4-(1,1-Difluoroethyl)-3- fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320712 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-2-fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320710 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3-fluorop...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320811 ((R)- or (S)-1-(1-(4-(1,1-Difluoroethyl)-3- fluorop...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320813 ((R)- or (S)-1-(1-(4-(1,1-Difluoroethyl)-3- fluorop...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320944 ((R)- or (S)-1-(1-(4- (difluoromethyl)-2- fluorophe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UPR 9023 Curated by PDSP Ki Database | Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320801 ((R)- or (S)-l-(1-(4-(1,1- Difluoroethyl)phenyl)-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320712 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-2-fluorop...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320799 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)phenyl)pro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320732 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)phenyl)-2-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320726 ((R)- or (S)-6-(Dimethylamino)- 1-(1-(2-fluoro-4- (...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320795 ((R)- or (S)-6-(Dimethylamino)-1-(1-(2- fluoro-4-(t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320797 ((R)- or (S)-1-(Cyclopropyl(2-fluoro-4- (trifluorom...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320801 ((R)- or (S)-l-(1-(4-(1,1- Difluoroethyl)phenyl)-2-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320670 ((R)- or (S)-6-(Dimethylamino)-3- (hydroxymethyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320817 ((R)- or (S)-6-(Dimethylamino)-1-(1-(3- fluoro-4-(t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320809 ((R)- or (S)-1-(1-(4-(1,1-Difluoroethyl)-2- fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320815 ((R)- or (S)-6-(Dimethylamino)-1-(1-(3- fluoro-4-(t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320770 ((R)- or (S)-6-(Dimethylamino)-3- (fluoromethyl)-1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320728 ((R)- or (S)-1-(Cyclopropyl(2- fluoro-4- (trifluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320789 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)phenyl)eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320793 ((R)- or (S)-6-(Dimethylamino)-1-(1-(2- fluoro-4-(t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320809 ((R)- or (S)-1-(1-(4-(1,1-Difluoroethyl)-2- fluorop...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320948 ((R)- or (S)-1- (Cyclopropyl(4-(1,1- difluoroethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | CHEMBL5268404 | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL UniChem | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320728 ((R)- or (S)-1-(Cyclopropyl(2- fluoro-4- (trifluoro...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320807 ((R)- or (S)-1-(Cyclopropyl(4-(1,1- difluoroethyl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320670 ((R)- or (S)-6-(Dimethylamino)-3- (hydroxymethyl)-1...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320706 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3- fluoro...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320756 (US10174037, Example 162 | US10174037, Example 163) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320706 ((R)- or (S)-1-(1-(4-(1,1- Difluoroethyl)-3- fluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320797 ((R)- or (S)-1-(Cyclopropyl(2-fluoro-4- (trifluorom...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM320774 ((R)- or (S)-1-(Cyclopropyl(3-fluoro-4- (trifluorom...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Macaca mulatta (Rhesus macaque)) | BDBM320770 ((R)- or (S)-6-(Dimethylamino)-3- (fluoromethyl)-1-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor... | US Patent US10174037 (2019) BindingDB Entry DOI: 10.7270/Q29K4DB7 | |||||||||||
More data for this Ligand-Target Pair |
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