Compile Data Set for Download or QSAR

Found 209 hits with Last Name = 'yudt' and Initial = 'mr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor by cellular reporter gene assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at cloned glucocorticoid receptor-ligand binding domain expressed in african green monkey COS7 cells by GAL4 luciferase reporter ...				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor ligand binding domain by two hybrid assay				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor by Gal4-DNA binding domain-hormone receptor LBD one-hybrid assay				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50401606 (CHEMBL2203825) Show SMILES CC(C)S(=O)(=O)Nc1ccc(cc1)-c1ccc(C#N)n1C Show InChI InChI=1S/C15H17N3O2S/c1-11(2)21(19,20)17-13-6-4-12(5-7-13)15-9-8-14(10-16)18(15)3/h4-9,11,17H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50228080 (2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrof...) Show SMILES CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12 |r,t:6| Show InChI InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at mineralocorticoid receptor ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by ...				J Nat Prod 72: 1944-8 (2009) Article DOI: 10.1021/np9004882 BindingDB Entry DOI: 10.7270/Q2R49RQR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50264285 (1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(C)(c3cccs3)c2c1)C#N Show InChI InChI=1S/C20H17N3O2S/c1-20(18-4-3-9-26-18)15-10-13(17-8-6-14(11-21)23(17)2)5-7-16(15)22-19(24)12-25-20/h3-10H,12H2,1-2H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from progesterone receptor in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50323591 (5-(4-(1-(hydroxyimino)-2,2-dimethylpropyl)phenyl)-...) Show SMILES Cn1c(ccc1-c1ccc(cc1)C(N=O)C(C)(C)C)C#N Show InChI InChI=1S/C17H19N3O/c1-17(2,3)16(19-21)13-7-5-12(6-8-13)15-10-9-14(11-18)20(15)4/h5-10,16H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50299880 (5-(1-hydroxy-3,3-dimethyl-1-(prop-2-ynyl)-2,3-dihy...) Show SMILES Cn1c(ccc1-c1ccc2c(c1)C(C)(C)CC2(O)CC#C)C#N Show InChI InChI=1S/C20H20N2O/c1-5-10-20(23)13-19(2,3)17-11-14(6-8-16(17)20)18-9-7-15(12-21)22(18)4/h1,6-9,11,23H,10,13H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor in human T47D cells assessed as progesteron-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 6666-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.008 BindingDB Entry DOI: 10.7270/Q2FJ2GVX
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50323590 (1-methyl-5-(4-pivaloylphenyl)-1H-pyrrole-2-carboni...) Show SMILES Cn1c(ccc1-c1ccc(cc1)C(=O)C(C)(C)C)C#N Show InChI InChI=1S/C17H18N2O/c1-17(2,3)16(20)13-7-5-12(6-8-13)15-10-9-14(11-18)19(15)4/h5-10H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luc...				J Nat Prod 72: 1944-8 (2009) Article DOI: 10.1021/np9004882 BindingDB Entry DOI: 10.7270/Q2R49RQR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50264310 (1-methyl-5-(5-methyl-2-oxo-5-(thiophen-3-yl)-1,2,3...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(C)(c3ccsc3)c2c1)C#N Show InChI InChI=1S/C20H17N3O2S/c1-20(14-7-8-26-12-14)16-9-13(18-6-4-15(10-21)23(18)2)3-5-17(16)22-19(24)11-25-20/h3-9,12H,11H2,1-2H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from progesterone receptor in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50169743 ((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...) Show SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc1cc(O)ccc31 |r| Show InChI InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor beta ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luci...				J Nat Prod 72: 1944-8 (2009) Article DOI: 10.1021/np9004882 BindingDB Entry DOI: 10.7270/Q2R49RQR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264284 (5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrah...) Show SMILES CC1(OCC(=O)Nc2ccc(cc12)-c1ccc([nH]1)C#N)c1cccs1 Show InChI InChI=1S/C19H15N3O2S/c1-19(17-3-2-8-25-17)14-9-12(15-7-5-13(10-20)21-15)4-6-16(14)22-18(23)11-24-19/h2-9,21H,11H2,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from progesterone receptor in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50169743 ((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...) Show SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc1cc(O)ccc31 |r| Show InChI InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luc...				J Nat Prod 72: 1944-8 (2009) Article DOI: 10.1021/np9004882 BindingDB Entry DOI: 10.7270/Q2R49RQR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50312006 (CHEMBL1076438 | Lecanindole D) Show SMILES C[C@@]12[C@H](Cc3c1[nH]c1ccccc31)CC[C@@]1(O)C(C)(C)[C@H](O)CC[C@]21C |r| Show InChI InChI=1S/C23H31NO2/c1-20(2)18(25)10-11-21(3)22(4)14(9-12-23(20,21)26)13-16-15-7-5-6-8-17(15)24-19(16)22/h5-8,14,18,24-26H,9-13H2,1-4H3/t14-,18+,21+,22+,23+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of progesterone from progesterone receptor in human T47D cells after 3 hrs				J Nat Prod 72: 1944-8 (2009) Article DOI: 10.1021/np9004882 BindingDB Entry DOI: 10.7270/Q2R49RQR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401601 (CHEMBL2203832) Show SMILES CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)c(F)c1 Show InChI InChI=1S/C14H14FN3O2S/c1-3-21(19,20)17-10-4-6-12(13(15)8-10)14-7-5-11(9-16)18(14)2/h4-8,17H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50323595 (5-(5-hydroxy-5-methyl-5,6,7,8-tetrahydronaphthalen...) Show SMILES Cn1c(ccc1-c1ccc2c(CCCC2(C)O)c1)C#N Show InChI InChI=1S/C17H18N2O/c1-17(20)9-3-4-12-10-13(5-7-15(12)17)16-8-6-14(11-18)19(16)2/h5-8,10,20H,3-4,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264352 (5-(5,5-di(furan-2-yl)-2-oxo-1,2,3,5-tetrahydrobenz...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(c3ccco3)(c3ccco3)c2c1)C#N Show InChI InChI=1S/C23H17N3O4/c1-26-16(13-24)7-9-19(26)15-6-8-18-17(12-15)23(20-4-2-10-28-20,21-5-3-11-29-21)30-14-22(27)25-18/h2-12H,14H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at androgen receptor ligand binding domain by two hybrid assay				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at androgen receptor by Gal4-DNA binding domain-hormone receptor LBD one-hybrid assay				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at cloned androgen receptor-ligand binding domain expressed in african green monkey COS7 cells by two hybrid luciferase assay				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50323594 (5-(5-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-1-...) Show SMILES Cn1c(ccc1-c1ccc2C(O)CCCc2c1)C#N Show InChI InChI=1S/C16H16N2O/c1-18-13(10-17)6-8-15(18)12-5-7-14-11(9-12)3-2-4-16(14)19/h5-9,16,19H,2-4H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401612 (CHEMBL2203819) Show SMILES Cn1c(ccc1-c1ccc(NS(C)(=O)=O)cc1)C#N Show InChI InChI=1S/C13H13N3O2S/c1-16-12(9-14)7-8-13(16)10-3-5-11(6-4-10)15-19(2,17)18/h3-8,15H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401600 (CHEMBL2203833) Show SMILES Cn1c(ccc1-c1ccc(NS(C)(=O)=O)cc1F)C#N Show InChI InChI=1S/C13H12FN3O2S/c1-17-10(8-15)4-6-13(17)11-5-3-9(7-12(11)14)16-20(2,18)19/h3-7,16H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401610 (CHEMBL2203821) Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1ccc(C#N)n1C Show InChI InChI=1S/C14H15N3O2S/c1-3-20(18,19)16-12-6-4-11(5-7-12)14-9-8-13(10-15)17(14)2/h4-9,16H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at androgen receptor by cellular reporter gene assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401608 (CHEMBL2203823) Show SMILES CCCS(=O)(=O)Nc1ccc(cc1)-c1ccc(C#N)n1C Show InChI InChI=1S/C15H17N3O2S/c1-3-10-21(19,20)17-13-6-4-12(5-7-13)15-9-8-14(11-16)18(15)2/h4-9,17H,3,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50299878 (5-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)-1-methyl-1...) Show SMILES Cn1c(ccc1-c1ccc2C(O)CCc2c1)C#N Show InChI InChI=1S/C15H14N2O/c1-17-12(9-16)4-6-14(17)11-2-5-13-10(8-11)3-7-15(13)18/h2,4-6,8,15,18H,3,7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor in human T47D cells assessed as progesteron-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 6666-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.008 BindingDB Entry DOI: 10.7270/Q2FJ2GVX
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50323596 (5-(5-hydroxy-5-(prop-1-ynyl)-5,6,7,8-tetrahydronap...) Show SMILES CC#CC1(O)CCCc2cc(ccc12)-c1ccc(C#N)n1C Show InChI InChI=1S/C19H18N2O/c1-3-10-19(22)11-4-5-14-12-15(6-8-17(14)19)18-9-7-16(13-20)21(18)2/h6-9,12,22H,4-5,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264432 (5-((5R)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-te...) Show SMILES CC[C@]1(OCC(=O)Nc2ccc(cc12)-c1ccc([nH]1)C#N)c1cccs1 |r| Show InChI InChI=1S/C20H17N3O2S/c1-2-20(18-4-3-9-26-18)15-10-13(16-8-6-14(11-21)22-16)5-7-17(15)23-19(24)12-25-20/h3-10,22H,2,12H2,1H3,(H,23,24)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264251 (5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1...) Show SMILES CC1(C)OCC(=O)Nc2ccc(cc12)-c1ccc([nH]1)C#N Show InChI InChI=1S/C16H15N3O2/c1-16(2)12-7-10(13-6-4-11(8-17)18-13)3-5-14(12)19-15(20)9-21-16/h3-7,18H,9H2,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from progesterone receptor in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264351 (1-methyl-5-(2-oxo-5,5-di(thiophen-2-yl)-1,2,3,5-te...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(c3cccs3)(c3cccs3)c2c1)C#N Show InChI InChI=1S/C23H17N3O2S2/c1-26-16(13-24)7-9-19(26)15-6-8-18-17(12-15)23(20-4-2-10-29-20,21-5-3-11-30-21)28-14-22(27)25-18/h2-12H,14H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401596 (CHEMBL2203836) Show SMILES CCS(=O)(=O)Nc1cc(F)c(-c2ccc(C#N)n2C)c(F)c1 |(36.99,-28.77,;35.66,-29.54,;34.32,-28.76,;33.54,-27.42,;35.08,-27.42,;32.99,-29.54,;31.65,-28.77,;31.65,-27.22,;30.31,-26.46,;30.31,-24.92,;28.99,-27.23,;27.66,-26.46,;27.69,-24.92,;26.24,-24.41,;25.31,-25.64,;23.77,-25.61,;22.23,-25.57,;26.19,-26.91,;25.68,-28.36,;28.98,-28.77,;27.65,-29.54,;30.32,-29.54,)| Show InChI InChI=1S/C14H13F2N3O2S/c1-3-22(20,21)18-9-6-11(15)14(12(16)7-9)13-5-4-10(8-17)19(13)2/h4-7,18H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor by cellular reporter gene assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50270630 (3-[5-Ethyl-5-(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,...) Show SMILES CCC1(OCC(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)C#N)c1ccco1 Show InChI InChI=1S/C22H17FN2O3/c1-2-22(20-4-3-7-27-20)18-11-15(5-6-19(18)25-21(26)13-28-22)16-8-14(12-24)9-17(23)10-16/h3-11H,2,13H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.8	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401599 (CHEMBL2203834) Show SMILES CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)c(c1)C(F)(F)F Show InChI InChI=1S/C15H14F3N3O2S/c1-3-24(22,23)20-10-4-6-12(13(8-10)15(16,17)18)14-7-5-11(9-19)21(14)2/h4-8,20H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50401596 (CHEMBL2203836) Show SMILES CCS(=O)(=O)Nc1cc(F)c(-c2ccc(C#N)n2C)c(F)c1 |(36.99,-28.77,;35.66,-29.54,;34.32,-28.76,;33.54,-27.42,;35.08,-27.42,;32.99,-29.54,;31.65,-28.77,;31.65,-27.22,;30.31,-26.46,;30.31,-24.92,;28.99,-27.23,;27.66,-26.46,;27.69,-24.92,;26.24,-24.41,;25.31,-25.64,;23.77,-25.61,;22.23,-25.57,;26.19,-26.91,;25.68,-28.36,;28.98,-28.77,;27.65,-29.54,;30.32,-29.54,)| Show InChI InChI=1S/C14H13F2N3O2S/c1-3-22(20,21)18-9-6-11(15)14(12(16)7-9)13-5-4-10(8-17)19(13)2/h4-7,18H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assay				Bioorg Med Chem Lett 22: 7119-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.077 BindingDB Entry DOI: 10.7270/Q2S183NW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50121165 (3-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-5...) Show SMILES CC1(C)C(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C17H13FN2O/c1-17(2)14-8-11(3-4-15(14)20-16(17)21)12-5-10(9-19)6-13(18)7-12/h3-8H,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50270631 (3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-be...) Show SMILES Fc1cc(cc(c1)-c1ccc2NC(=O)COC(c3ccco3)(c3ccco3)c2c1)C#N Show InChI InChI=1S/C24H15FN2O4/c25-18-10-15(13-26)9-17(11-18)16-5-6-20-19(12-16)24(21-3-1-7-29-21,22-4-2-8-30-22)31-14-23(28)27-20/h1-12H,14H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50299877 (5-(1-(hydroxyimino)-3,3-dimethyl-2,3-dihydro-1H-in...) Show SMILES Cn1c(ccc1-c1ccc2C(CC(C)(C)c2c1)N=O)C#N Show InChI InChI=1S/C17H17N3O/c1-17(2)9-15(19-21)13-6-4-11(8-14(13)17)16-7-5-12(10-18)20(16)3/h4-8,15H,9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor in human T47D cells assessed as progesteron-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 6666-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.008 BindingDB Entry DOI: 10.7270/Q2FJ2GVX
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264353 (1-methyl-5-(2-oxo-5,5-diphenyl-1,2,3,5-tetrahydrob...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(c3ccccc3)(c3ccccc3)c2c1)C#N Show InChI InChI=1S/C27H21N3O2/c1-30-22(17-28)13-15-25(30)19-12-14-24-23(16-19)27(32-18-26(31)29-24,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-16H,18H2,1H3,(H,29,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264312 (5-(5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahy...) Show SMILES CCC1(OCC(=O)Nc2ccc(cc12)-c1ccc(C#N)n1C)c1cccs1 Show InChI InChI=1S/C21H19N3O2S/c1-3-21(19-5-4-10-27-19)16-11-14(18-9-7-15(12-22)24(18)2)6-8-17(16)23-20(25)13-26-21/h4-11H,3,13H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50270622 (7-(3-Fluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-be...) Show SMILES CC1(C)OCC(=O)Nc2ccc(cc12)-c1cccc(F)c1 Show InChI InChI=1S/C17H16FNO2/c1-17(2)14-9-12(11-4-3-5-13(18)8-11)6-7-15(14)19-16(20)10-21-17/h3-9H,10H2,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.9	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50270573 (7-(3-Chloro-5-fluorophenyl)-5,5-dimethyl-1,5-dihyd...) Show SMILES CC1(C)OCC(=O)Nc2ccc(cc12)-c1cc(F)cc(Cl)c1 Show InChI InChI=1S/C17H15ClFNO2/c1-17(2)14-7-10(11-5-12(18)8-13(19)6-11)3-4-15(14)20-16(21)9-22-17/h3-8H,9H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50270624 (7-(2,3-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,...) Show SMILES CC1(C)OCC(=O)Nc2ccc(cc12)-c1cccc(F)c1F Show InChI InChI=1S/C17H15F2NO2/c1-17(2)12-8-10(11-4-3-5-13(18)16(11)19)6-7-14(12)20-15(21)9-22-17/h3-8H,9H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50323603 (5-(4-(1-(hydroxyimino)propyl)phenyl)-1-methyl-1H-p...) Show SMILES CCC(N=O)c1ccc(cc1)-c1ccc(C#N)n1C Show InChI InChI=1S/C15H15N3O/c1-3-14(17-19)11-4-6-12(7-5-11)15-9-8-13(10-16)18(15)2/h4-9,14H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 20: 4816-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.109 BindingDB Entry DOI: 10.7270/Q2ZW1MX6
					More data for this Ligand-Target Pair

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