Found 143 hits with Last Name = 'zhao' and Initial = 'ds' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185726
(CHEMBL3823385)Show InChI InChI=1S/C14H11N3O3/c1-19-11-4-2-10(3-5-11)12-6-7-13(20-12)14(18)17-9-15-8-16-17/h2-9H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466937
(CHEMBL4170548)Show InChI InChI=1S/C21H19NO3/c1-24-17-10-8-16(9-11-17)19-12-13-20(25-19)21(23)22-14-4-6-15-5-2-3-7-18(15)22/h2-3,5,7-13H,4,6,14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231313
(CHEMBL4085883)Show InChI InChI=1S/C16H15N3O3/c1-10-8-11(2)19(18-10)16(20)14-9-22-15(17-14)12-4-6-13(21-3)7-5-12/h4-9H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466922
(CHEMBL4292472)Show InChI InChI=1S/C17H16N2O3/c1-11-10-12(2)19(18-11)17(20)16-9-8-15(22-16)13-4-6-14(21-3)7-5-13/h4-10H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466958
(CHEMBL4167454)Show InChI InChI=1S/C21H19NO3/c1-24-18-8-6-16(7-9-18)19-10-11-20(25-19)21(23)22-13-12-15-4-2-3-5-17(15)14-22/h2-11H,12-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466951
(CHEMBL4167824)Show SMILES Fc1ccc(-c2ccc(o2)C(=O)N2CCCc3ccccc23)c(F)c1 Show InChI InChI=1S/C20H15F2NO2/c21-14-7-8-15(16(22)12-14)18-9-10-19(25-18)20(24)23-11-3-5-13-4-1-2-6-17(13)23/h1-2,4,6-10,12H,3,5,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185739
(CHEMBL3823670)Show InChI InChI=1S/C15H12N2O3/c1-19-12-5-3-11(4-6-12)13-7-8-14(20-13)15(18)17-10-2-9-16-17/h2-10H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466945
(CHEMBL4176569)Show SMILES Fc1ccc(-c2ccc(o2)C(=O)N2CCc3ccccc3C2)c(F)c1 Show InChI InChI=1S/C20H15F2NO2/c21-15-5-6-16(17(22)11-15)18-7-8-19(25-18)20(24)23-10-9-13-3-1-2-4-14(13)12-23/h1-8,11H,9-10,12H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231320
(CHEMBL4084152)Show InChI InChI=1S/C14H11N3O3/c1-19-11-5-3-10(4-6-11)13-16-12(9-20-13)14(18)17-8-2-7-15-17/h2-9H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466925
(CHEMBL4294394)Show InChI InChI=1S/C16H12F2N2O2/c1-9-7-10(2)20(19-9)16(21)15-6-5-14(22-15)12-4-3-11(17)8-13(12)18/h3-8H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466957
(CHEMBL4172687)Show InChI InChI=1S/C20H16ClNO2/c21-16-9-7-15(8-10-16)18-11-12-19(24-18)20(23)22-13-3-5-14-4-1-2-6-17(14)22/h1-2,4,6-12H,3,5,13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185736
(CHEMBL3823501)Show InChI InChI=1S/C13H8ClN3O2/c14-10-3-1-9(2-4-10)11-5-6-12(19-11)13(18)17-8-15-7-16-17/h1-8H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466924
(CHEMBL4285675)Show InChI InChI=1S/C16H13ClN2O2/c1-10-9-11(2)19(18-10)16(20)15-8-7-14(21-15)12-3-5-13(17)6-4-12/h3-9H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466935
(CHEMBL4171991)Show InChI InChI=1S/C20H16ClNO2/c21-17-7-5-15(6-8-17)18-9-10-19(24-18)20(23)22-12-11-14-3-1-2-4-16(14)13-22/h1-10H,11-13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231312
(CHEMBL4104696)Show InChI InChI=1S/C15H12ClN3O2/c1-9-7-10(2)19(18-9)15(20)13-8-21-14(17-13)11-3-5-12(16)6-4-11/h3-8H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231324
(CHEMBL4098616)Show InChI InChI=1S/C16H15N3O3/c1-10-7-11(2)19(18-10)16(20)14-9-22-15(17-14)12-5-4-6-13(8-12)21-3/h4-9H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185730
(CHEMBL3823761)Show InChI InChI=1S/C13H7F2N3O2/c14-8-1-2-9(10(15)5-8)11-3-4-12(20-11)13(19)18-7-16-6-17-18/h1-7H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231224
(CHEMBL4091911)Show InChI InChI=1S/C13H8ClN3O2/c14-10-4-2-9(3-5-10)12-16-11(8-19-12)13(18)17-7-1-6-15-17/h1-8H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185727
(CHEMBL3823288)Show InChI InChI=1S/C14H11N3O2/c1-10-2-4-11(5-3-10)12-6-7-13(19-12)14(18)17-9-15-8-16-17/h2-9H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185749
(CHEMBL3823140)Show InChI InChI=1S/C14H9ClN2O2/c15-11-4-2-10(3-5-11)12-6-7-13(19-12)14(18)17-9-1-8-16-17/h1-9H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231289
(CHEMBL4096292)Show InChI InChI=1S/C14H11N3O3/c1-19-11-5-2-4-10(8-11)13-16-12(9-20-13)14(18)17-7-3-6-15-17/h2-9H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466941
(CHEMBL4168223)Show InChI InChI=1S/C20H16FNO2/c21-16-9-7-15(8-10-16)18-11-12-19(24-18)20(23)22-13-3-5-14-4-1-2-6-17(14)22/h1-2,4,6-12H,3,5,13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185743
(CHEMBL3823585)Show InChI InChI=1S/C14H8F2N2O2/c15-9-2-3-10(11(16)8-9)12-4-5-13(20-12)14(19)18-7-1-6-17-18/h1-8H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231314
(CHEMBL4064343)Show InChI InChI=1S/C16H15N3O2/c1-10-4-6-13(7-5-10)15-17-14(9-21-15)16(20)19-12(3)8-11(2)18-19/h4-9H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
ATP-dependent translocase ABCB1
(Homo sapiens (Human)) | BDBM50569169
(CHEMBL4852792)Show SMILES COc1cccc(c1)-c1ccc(o1)C(=O)N1CCc2cc(OC)c(OC)cc2C1 | PDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113336 BindingDB Entry DOI: 10.7270/Q2QF8XMW |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466923
(CHEMBL4277735)Show InChI InChI=1S/C16H13FN2O2/c1-10-9-11(2)19(18-10)16(20)15-8-7-14(21-15)12-3-5-13(17)6-4-12/h3-9H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466949
(CHEMBL4170840)Show InChI InChI=1S/C20H16FNO2/c21-17-7-5-15(6-8-17)18-9-10-19(24-18)20(23)22-12-11-14-3-1-2-4-16(14)13-22/h1-10H,11-13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
ATP-dependent translocase ABCB1
(Homo sapiens (Human)) | BDBM50569185
(CHEMBL4856166)Show SMILES COc1cc2CCN(Cc2cc1OC)C(=O)c1ccc(o1)-c1ccc2OCOc2c1 | PDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113336 BindingDB Entry DOI: 10.7270/Q2QF8XMW |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50231320
(CHEMBL4084152)Show InChI InChI=1S/C14H11N3O3/c1-19-11-5-3-10(4-6-11)13-16-12(9-20-13)14(18)17-8-2-7-15-17/h2-9H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231317
(CHEMBL4082110)Show InChI InChI=1S/C15H12FN3O2/c1-9-7-10(2)19(18-9)15(20)13-8-21-14(17-13)11-3-5-12(16)6-4-11/h3-8H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466917
(CHEMBL4281168)Show InChI InChI=1S/C17H16N2O2/c1-11-4-6-14(7-5-11)15-8-9-16(21-15)17(20)19-13(3)10-12(2)18-19/h4-10H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185731
(CHEMBL3823865)Show InChI InChI=1S/C13H8FN3O2/c14-10-3-1-9(2-4-10)11-5-6-12(19-11)13(18)17-8-15-7-16-17/h1-8H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
ATP-dependent translocase ABCB1
(Homo sapiens (Human)) | BDBM50032260
(CHEMBL3352974)Show SMILES COc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2cc(OC)c(OC)cc2C1 Show InChI InChI=1S/C23H23NO5/c1-26-18-6-4-15(5-7-18)19-8-9-20(29-19)23(25)24-11-10-16-12-21(27-2)22(28-3)13-17(16)14-24/h4-9,12-13H,10-11,14H2,1-3H3 | PDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113336 BindingDB Entry DOI: 10.7270/Q2QF8XMW |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466933
(CHEMBL4167151)Show InChI InChI=1S/C21H19NO2/c1-15-8-10-17(11-9-15)19-12-13-20(24-19)21(23)22-14-4-6-16-5-2-3-7-18(16)22/h2-3,5,7-13H,4,6,14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50466946
(CHEMBL4164011)Show InChI InChI=1S/C21H19NO2/c1-15-6-8-17(9-7-15)19-10-11-20(24-19)21(23)22-13-12-16-4-2-3-5-18(16)14-22/h2-11H,12-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50466922
(CHEMBL4292472)Show InChI InChI=1S/C17H16N2O3/c1-11-10-12(2)19(18-11)17(20)16-9-8-15(22-16)13-4-6-14(21-3)7-5-13/h4-10H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate measured after 30 mins |
Bioorg Med Chem Lett 28: 3276-3280 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3 |
More data for this Ligand-Target Pair | |
ATP-dependent translocase ABCB1
(Homo sapiens (Human)) | BDBM50569171
(CHEMBL4850552)Show SMILES COc1ccc(cc1OC)-c1ccc(o1)C(=O)N1CCc2cc(OC)c(OC)cc2C1 | PDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113336 BindingDB Entry DOI: 10.7270/Q2QF8XMW |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50231309
(CHEMBL4078947)Show InChI InChI=1S/C13H8FN3O2/c14-10-4-2-9(3-5-10)12-16-11(8-19-12)13(18)17-7-1-6-15-17/h1-8H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50466958
(CHEMBL4167454)Show InChI InChI=1S/C21H19NO3/c1-24-18-8-6-16(7-9-18)19-10-11-20(25-19)21(23)22-13-12-15-4-2-3-5-17(15)14-22/h2-11H,12-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50185744
(CHEMBL3822601)Show InChI InChI=1S/C14H9FN2O2/c15-11-4-2-10(3-5-11)12-6-7-13(19-12)14(18)17-9-1-8-16-17/h1-9H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 26: 3632-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.002 BindingDB Entry DOI: 10.7270/Q27946MZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50466937
(CHEMBL4170548)Show InChI InChI=1S/C21H19NO3/c1-24-17-10-8-16(9-11-17)19-12-13-20(25-19)21(23)22-14-4-6-15-5-2-3-7-18(15)22/h2-3,5,7-13H,4,6,14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins |
Bioorg Med Chem Lett 28: 3271-3275 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50231313
(CHEMBL4085883)Show InChI InChI=1S/C16H15N3O3/c1-10-8-11(2)19(18-10)16(20)14-9-22-15(17-14)12-4-6-13(21-3)7-5-12/h4-9H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University
Curated by ChEMBL
| Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]cAMP as substrate after 30 mins |
Bioorg Med Chem 25: 1852-1859 (2017)
Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3 |
More data for this Ligand-Target Pair | |
ATP-dependent translocase ABCB1
(Homo sapiens (Human)) | BDBM50569183
(CHEMBL4856561)Show SMILES COc1cc2CCN(Cc2cc1OC)C(=O)c1ccc(o1)-c1ccc(OC(F)(F)F)cc1 | PDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113336 BindingDB Entry DOI: 10.7270/Q2QF8XMW |
More data for this Ligand-Target Pair | |