Compile Data Set for Download or QSAR

Found 794 hits with Last Name = 'zheng' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Menin (Homo sapiens (Human))	BDBM50516582 (CHEMBL4449381) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)NC)[C@@]1(CN(C)Cc2ccccc12)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 |r| Show InChI InChI=1S/C37H47N5O4S/c1-38-36(43)46-35-9-5-8-34(35)37(26-40(2)25-28-6-3-4-7-33(28)37)29-16-20-41(21-17-29)22-27-23-42(24-27)30-10-12-31(13-11-30)47(44,45)32-14-18-39-19-15-32/h3-4,6-7,10-15,18-19,27,29,34-35H,5,8-9,16-17,20-26H2,1-2H3,(H,38,43)/t34-,35-,37-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Menin (Homo sapiens (Human))	BDBM50516569 (CHEMBL4585198 | US10899738, Cpd. No 148) Show SMILES CCN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 Show InChI InChI=1S/C36H46N4O2S/c1-2-38-26-29-7-3-6-10-35(29)36(27-38,30-8-4-5-9-30)31-17-21-39(22-18-31)23-28-24-40(25-28)32-11-13-33(14-12-32)43(41,42)34-15-19-37-20-16-34/h3,6-7,10-16,19-20,28,30-31H,2,4-5,8-9,17-18,21-27H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516570 (CHEMBL4551865 | US10899738, Cpd. No 48) Show SMILES CC(C)N1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 Show InChI InChI=1S/C37H48N4O2S/c1-28(2)41-26-30-7-3-6-10-36(30)37(27-41,31-8-4-5-9-31)32-17-21-39(22-18-32)23-29-24-40(25-29)33-11-13-34(14-12-33)44(42,43)35-15-19-38-20-16-35/h3,6-7,10-16,19-20,28-29,31-32H,4-5,8-9,17-18,21-27H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516571 (CHEMBL4592636 | US10899738, Cpd. No 50) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CC3CC3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C38H48N4O2S/c43-45(44,36-15-19-39-20-16-36)35-13-11-34(12-14-35)42-25-30(26-42)24-40-21-17-33(18-22-40)38(32-6-2-3-7-32)28-41(23-29-9-10-29)27-31-5-1-4-8-37(31)38/h1,4-5,8,11-16,19-20,29-30,32-33H,2-3,6-7,9-10,17-18,21-28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516567 (CHEMBL4449199 | US10899738, Cpd. No 51) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CNCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C34H42N4O2S/c39-41(40,32-13-17-35-18-14-32)31-11-9-30(10-12-31)38-23-26(24-38)22-37-19-15-29(16-20-37)34(28-6-2-3-7-28)25-36-21-27-5-1-4-8-33(27)34/h1,4-5,8-14,17-18,26,28-29,36H,2-3,6-7,15-16,19-25H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516554 (CHEMBL4522767 | US10899738, Cpd. No 49) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(Cc3ccccc23)C2CCC2)C2CCCC2)C1 Show InChI InChI=1S/C38H48N4O2S/c43-45(44,36-16-20-39-21-17-36)35-14-12-34(13-15-35)41-25-29(26-41)24-40-22-18-32(19-23-40)38(31-7-2-3-8-31)28-42(33-9-5-10-33)27-30-6-1-4-11-37(30)38/h1,4,6,11-17,20-21,29,31-33H,2-3,5,7-10,18-19,22-28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516568 (CHEMBL4516680) Show SMILES CN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 Show InChI InChI=1S/C35H44N4O2S/c1-37-25-28-6-2-5-9-34(28)35(26-37,29-7-3-4-8-29)30-16-20-38(21-17-30)22-27-23-39(24-27)31-10-12-32(13-11-31)42(40,41)33-14-18-36-19-15-33/h2,5-6,9-15,18-19,27,29-30H,3-4,7-8,16-17,20-26H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516565 (CHEMBL4578509 | US10899738, Cpd. No 92) Show SMILES O=S(=O)(C1CCCCC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C35H49N3O2S/c39-41(40,32-11-2-1-3-12-32)33-16-14-31(15-17-33)38-25-27(26-38)24-37-22-19-30(20-23-37)35(29-9-5-6-10-29)34-13-7-4-8-28(34)18-21-36-35/h4,7-8,13-17,27,29-30,32,36H,1-3,5-6,9-12,18-26H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516581 (CHEMBL4458829) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)NC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H37N5O2/c1-34-30(37)38-29-9-5-8-28(29)31(22-33,25-6-3-2-4-7-25)26-14-16-35(17-15-26)19-24-20-36(21-24)27-12-10-23(18-32)11-13-27/h2-4,6-7,10-13,24,26,28-29H,5,8-9,14-17,19-21H2,1H3,(H,34,37)/t28-,29-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516574 (CHEMBL4444304 | US10899738, Cpd. No 54) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CCN3CCOCC3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C40H53N5O3S/c46-49(47,38-13-17-41-18-14-38)37-11-9-36(10-12-37)45-28-32(29-45)27-43-19-15-35(16-20-43)40(34-6-2-3-7-34)31-44(22-21-42-23-25-48-26-24-42)30-33-5-1-4-8-39(33)40/h1,4-5,8-14,17-18,32,34-35H,2-3,6-7,15-16,19-31H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516564 (CHEMBL4459554 | US10899738, Cpd. No 146) Show SMILES O=S(=O)(C1CCCC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C34H47N3O2S/c38-40(39,31-10-4-5-11-31)32-15-13-30(14-16-32)37-24-26(25-37)23-36-21-18-29(19-22-36)34(28-8-2-3-9-28)33-12-6-1-7-27(33)17-20-35-34/h1,6-7,12-16,26,28-29,31,35H,2-5,8-11,17-25H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516553 (CHEMBL4476073 | US10899738, Cpd. No 151) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C34H42N4O2S/c39-41(40,32-14-18-35-19-15-32)31-11-9-30(10-12-31)38-24-26(25-38)23-37-21-16-29(17-22-37)34(28-6-2-3-7-28)33-8-4-1-5-27(33)13-20-36-34/h1,4-5,8-12,14-15,18-19,26,28-29,36H,2-3,6-7,13,16-17,20-25H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516566 (CHEMBL4436641 | US10899738, Cpd. No 149) Show SMILES O=S(=O)(c1ccccc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C35H43N3O2S/c39-41(40,32-11-2-1-3-12-32)33-16-14-31(15-17-33)38-25-27(26-38)24-37-22-19-30(20-23-37)35(29-9-5-6-10-29)34-13-7-4-8-28(34)18-21-36-35/h1-4,7-8,11-17,27,29-30,36H,5-6,9-10,18-26H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516572 (CHEMBL4532417 | US10899738, Cpd. No 52) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CC3COC3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C38H48N4O3S/c43-46(44,36-13-17-39-18-14-36)35-11-9-34(10-12-35)42-23-29(24-42)21-40-19-15-33(16-20-40)38(32-6-2-3-7-32)28-41(22-30-26-45-27-30)25-31-5-1-4-8-37(31)38/h1,4-5,8-14,17-18,29-30,32-33H,2-3,6-7,15-16,19-28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516549 (CHEMBL4470192 | US10899738, Cpd. No 135) Show SMILES O=S(=O)(C1CC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C32H43N3O2S/c36-38(37,30-13-14-30)29-11-9-28(10-12-29)35-22-24(23-35)21-34-19-16-27(17-20-34)32(26-6-2-3-7-26)31-8-4-1-5-25(31)15-18-33-32/h1,4-5,8-12,24,26-27,30,33H,2-3,6-7,13-23H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516583 (CHEMBL4568235) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H37N5O2/c1-38-30(37)34-29-9-5-8-28(29)31(22-33,25-6-3-2-4-7-25)26-14-16-35(17-15-26)19-24-20-36(21-24)27-12-10-23(18-32)11-13-27/h2-4,6-7,10-13,24,26,28-29H,5,8-9,14-17,19-21H2,1H3,(H,34,37)/t28-,29-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516579 (CHEMBL4452253) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)CC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C32H38N4O2/c1-2-31(37)38-30-10-6-9-29(30)32(23-34,26-7-4-3-5-8-26)27-15-17-35(18-16-27)20-25-21-36(22-25)28-13-11-24(19-33)12-14-28/h3-5,7-8,11-14,25,27,29-30H,2,6,9-10,15-18,20-22H2,1H3/t29-,30-,32+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516561 (CHEMBL4460234 | US10899738, Cpd. No 133) Show SMILES CCS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C31H43N3O2S/c1-2-37(35,36)29-13-11-28(12-14-29)34-22-24(23-34)21-33-19-16-27(17-20-33)31(26-8-4-5-9-26)30-10-6-3-7-25(30)15-18-32-31/h3,6-7,10-14,24,26-27,32H,2,4-5,8-9,15-23H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516559 (CHEMBL4446177 | US10899738, Cpd. No 129) Show SMILES N#Cc1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H38N4/c31-19-23-9-11-28(12-10-23)34-21-24(22-34)20-33-17-14-27(15-18-33)30(26-6-2-3-7-26)29-8-4-1-5-25(29)13-16-32-30/h1,4-5,8-12,24,26-27,32H,2-3,6-7,13-18,20-22H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516563 (CHEMBL4581439 | US10899738, Cpd. No 85) Show SMILES O=S(=O)(C1CCC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C33H45N3O2S/c37-39(38,30-9-5-10-30)31-14-12-29(13-15-31)36-23-25(24-36)22-35-20-17-28(18-21-35)33(27-7-2-3-8-27)32-11-4-1-6-26(32)16-19-34-33/h1,4,6,11-15,25,27-28,30,34H,2-3,5,7-10,16-24H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516578 (CHEMBL4453006) Show SMILES [H][C@@]1(CCC[C@@H]1OC(C)=O)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H36N4O2/c1-23(36)37-30-9-5-8-29(30)31(22-33,26-6-3-2-4-7-26)27-14-16-34(17-15-27)19-25-20-35(21-25)28-12-10-24(18-32)11-13-28/h2-4,6-7,10-13,25,27,29-30H,5,8-9,14-17,19-21H2,1H3/t29-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516562 (CHEMBL4467100 | US10899738, Cpd. No 134) Show SMILES CC(C)S(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C32H45N3O2S/c1-24(2)38(36,37)30-13-11-29(12-14-30)35-22-25(23-35)21-34-19-16-28(17-20-34)32(27-8-4-5-9-27)31-10-6-3-7-26(31)15-18-33-32/h3,6-7,10-14,24-25,27-28,33H,4-5,8-9,15-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516547 (CHEMBL4448045 | US10899738, Cpd. No 27) Show SMILES N#Cc1ccc(OCCCN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)cc1 Show InChI InChI=1S/C29H37N3O/c30-22-23-10-12-27(13-11-23)33-21-5-18-32-19-15-26(16-20-32)29(25-7-2-3-8-25)28-9-4-1-6-24(28)14-17-31-29/h1,4,6,9-13,25-26,31H,2-3,5,7-8,14-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516548 (CHEMBL4466955 | US10899738, Cpd. No 113) Show SMILES N#Cc1ccc(cc1)N1CCC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C31H40N4/c32-21-24-9-11-29(12-10-24)35-20-14-25(23-35)22-34-18-15-28(16-19-34)31(27-6-2-3-7-27)30-8-4-1-5-26(30)13-17-33-31/h1,4-5,8-12,25,27-28,33H,2-3,6-7,13-20,22-23H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516552 (CHEMBL4565646) Show SMILES [H][C@@]1(CCC[C@@H]1NC(C)=O)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H37N5O/c1-23(37)34-30-9-5-8-29(30)31(22-33,26-6-3-2-4-7-26)27-14-16-35(17-15-27)19-25-20-36(21-25)28-12-10-24(18-32)11-13-28/h2-4,6-7,10-13,25,27,29-30H,5,8-9,14-17,19-21H2,1H3,(H,34,37)/t29-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516560 (CHEMBL4592512 | US10899738, Cpd. No 132) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H41N3O2S/c1-36(34,35)28-12-10-27(11-13-28)33-21-23(22-33)20-32-18-15-26(16-19-32)30(25-7-3-4-8-25)29-9-5-2-6-24(29)14-17-31-30/h2,5-6,9-13,23,25-26,31H,3-4,7-8,14-22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50496346 (CHEMBL3126196) Show SMILES NC(C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1 Show InChI InChI=1S/C27H35N3O/c28-21-22-11-13-26(14-12-22)31-20-6-17-30-18-15-25(16-19-30)27(29,24-9-4-5-10-24)23-7-2-1-3-8-23/h1-3,7-8,11-14,24-25H,4-6,9-10,15-20,29H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Menin (Homo sapiens (Human))	BDBM50516557 (CHEMBL4537683 | US10899738, Cpd. No 55) Show SMILES N#Cc1ccc(cc1)N1CCC(CC1)N1CCC(CC1)C1(NCCc2ccccc12)C1CCCC1 Show InChI InChI=1S/C31H40N4/c32-23-24-9-11-28(12-10-24)35-21-16-29(17-22-35)34-19-14-27(15-20-34)31(26-6-2-3-7-26)30-8-4-1-5-25(30)13-18-33-31/h1,4-5,8-12,26-27,29,33H,2-3,6-7,13-22H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	207	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516580 (CHEMBL4453547) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)CCC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C33H40N4O2/c1-2-7-32(38)39-31-11-6-10-30(31)33(24-35,27-8-4-3-5-9-27)28-16-18-36(19-17-28)21-26-22-37(23-26)29-14-12-25(20-34)13-15-29/h3-5,8-9,12-15,26,28,30-31H,2,6-7,10-11,16-19,21-23H2,1H3/t30-,31-,33+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516573 (CHEMBL4448156 | US10899738, Cpd. No 53) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(Cc3ccncc3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C40H47N5O2S/c46-48(47,38-15-21-42-22-16-38)37-11-9-36(10-12-37)45-27-32(28-45)26-43-23-17-35(18-24-43)40(34-6-2-3-7-34)30-44(25-31-13-19-41-20-14-31)29-33-5-1-4-8-39(33)40/h1,4-5,8-16,19-22,32,34-35H,2-3,6-7,17-18,23-30H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	361	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516550 (CHEMBL4533602) Show SMILES N#Cc1ccc(cc1)N1CC(CN2CCC(CC2)C(C#N)(C2CCCC2)c2ccccc2)C1 Show InChI InChI=1S/C29H34N4/c30-18-23-10-12-28(13-11-23)33-20-24(21-33)19-32-16-14-27(15-17-32)29(22-31,26-8-4-5-9-26)25-6-2-1-3-7-25/h1-3,6-7,10-13,24,26-27H,4-5,8-9,14-17,19-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516551 (CHEMBL4462347) Show SMILES [H][C@]1(CCC[C@H]1OC(C)=O)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H36N4O2/c1-23(36)37-30-9-5-8-29(30)31(22-33,26-6-3-2-4-7-26)27-14-16-34(17-15-27)19-25-20-35(21-25)28-12-10-24(18-32)11-13-28/h2-4,6-7,10-13,25,27,29-30H,5,8-9,14-17,19-21H2,1H3/t29-,30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516556 (CHEMBL4576593) Show SMILES N#Cc1ccc(OCCCCN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)cc1 Show InChI InChI=1S/C30H39N3O/c31-23-24-11-13-28(14-12-24)34-22-6-5-19-33-20-16-27(17-21-33)30(26-8-2-3-9-26)29-10-4-1-7-25(29)15-18-32-30/h1,4,7,10-14,26-27,32H,2-3,5-6,8-9,15-22H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516577 (CHEMBL4457683) Show SMILES [H][C@@]1(CCC[C@@H]1OCC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H38N4O/c1-2-36-30-10-6-9-29(30)31(23-33,26-7-4-3-5-8-26)27-15-17-34(18-16-27)20-25-21-35(22-25)28-13-11-24(19-32)12-14-28/h3-5,7-8,11-14,25,27,29-30H,2,6,9-10,15-18,20-22H2,1H3/t29-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516558 (CHEMBL4528850 | US10899738, Cpd. No 115) Show SMILES N#Cc1ccc(cc1)N1CCCC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C32H42N4/c33-22-25-11-13-30(14-12-25)36-19-5-6-26(24-36)23-35-20-16-29(17-21-35)32(28-8-2-3-9-28)31-10-4-1-7-27(31)15-18-34-32/h1,4,7,10-14,26,28-29,34H,2-3,5-6,8-9,15-21,23-24H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516575 (CHEMBL4515980) Show SMILES [H][C@@]1(CCC[C@@H]1OC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C30H36N4O/c1-35-29-9-5-8-28(29)30(22-32,25-6-3-2-4-7-25)26-14-16-33(17-15-26)19-24-20-34(21-24)27-12-10-23(18-31)11-13-27/h2-4,6-7,10-13,24,26,28-29H,5,8-9,14-17,19-21H2,1H3/t28-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516555 (CHEMBL4570651) Show SMILES N#Cc1ccc(OCCN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)cc1 Show InChI InChI=1S/C28H35N3O/c29-21-22-9-11-26(12-10-22)32-20-19-31-17-14-25(15-18-31)28(24-6-2-3-7-24)27-8-4-1-5-23(27)13-16-30-28/h1,4-5,8-12,24-25,30H,2-3,6-7,13-20H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516576 (CHEMBL4474336) Show SMILES [H][C@]1(CCC[C@H]1OC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C30H36N4O/c1-35-29-9-5-8-28(29)30(22-32,25-6-3-2-4-7-25)26-14-16-33(17-15-26)19-24-20-34(21-24)27-12-10-23(18-31)11-13-27/h2-4,6-7,10-13,24,26,28-29H,5,8-9,14-17,19-21H2,1H3/t28-,29-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331094 (4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O Show InChI InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...				Eur J Med Chem 175: 349-356 (2019) Article DOI: 10.1016/j.ejmech.2019.04.015 BindingDB Entry DOI: 10.7270/Q21V5JC0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50524583 (CHEMBL4455006 | US10980809, Example 70) Show SMILES Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ncnc3cc(OCCCN4CCOCC4)c4OCCOc4c23)cc1F)C(F)(F)F Show InChI InChI=1S/C31H28F5N5O6/c32-20-4-2-18(31(34,35)36)14-23(20)40-30(42)39-22-5-3-19(15-21(22)33)47-29-26-24(37-17-38-29)16-25(27-28(26)46-13-12-45-27)44-9-1-6-41-7-10-43-11-8-41/h2-5,14-17H,1,6-13H2,(H2,39,40,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...				Eur J Med Chem 175: 349-356 (2019) Article DOI: 10.1016/j.ejmech.2019.04.015 BindingDB Entry DOI: 10.7270/Q21V5JC0
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50511905 (CHEMBL4530300) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN1CCC1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN2CC(F)(F)C2)CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C43H57F3N6O5S/c1-57-41(54)47-39-9-3-8-38(39)43(30-49-18-5-19-49,33-6-2-7-34(44)22-33)32-15-20-48(21-16-32)23-31-24-51(25-31)35-11-13-36(14-12-35)58(55,56)37-26-52(27-37)40(53)10-4-17-50-28-42(45,46)29-50/h2,4,6-7,10-14,22,31-32,37-39H,3,5,8-9,15-21,23-30H2,1H3,(H,47,54)/b10-4+/t38-,39-,43-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay				J Med Chem 63: 4997-5010 (2020) Article DOI: 10.1021/acs.jmedchem.0c00547 BindingDB Entry DOI: 10.7270/Q2QR51G9
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50032821 (CHEMBL3355178) Show SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)Nc1cnn(c1)C1CCNC1 Show InChI InChI=1S/C24H23ClN8O2/c25-21-6-1-2-7-22(21)31-24(35)30-18-12-27-32(15-18)19-5-3-4-16(10-19)23(34)29-17-11-28-33(14-17)20-8-9-26-13-20/h1-7,10-12,14-15,20,26H,8-9,13H2,(H,29,34)(H2,30,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50524586 (CHEMBL4449250 | US10980809, Example 65) Show SMILES Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ncnc3cc(OCCCN4CCOCC4)c4OCCOc4c23)cc1)C(F)(F)F Show InChI InChI=1S/C31H29F4N5O6/c32-22-7-2-19(31(33,34)35)16-23(22)39-30(41)38-20-3-5-21(6-4-20)46-29-26-24(36-18-37-29)17-25(27-28(26)45-15-14-44-27)43-11-1-8-40-9-12-42-13-10-40/h2-7,16-18H,1,8-15H2,(H2,38,39,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...				Eur J Med Chem 175: 349-356 (2019) Article DOI: 10.1016/j.ejmech.2019.04.015 BindingDB Entry DOI: 10.7270/Q21V5JC0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50524587 (CHEMBL4466426 | US10980809, Example 20) Show SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c2c2OCCOc12 Show InChI InChI=1S/C25H18F4N4O5/c1-35-19-11-18-20(22-21(19)36-8-9-37-22)23(31-12-30-18)38-15-5-3-14(4-6-15)32-24(34)33-17-10-13(25(27,28)29)2-7-16(17)26/h2-7,10-12H,8-9H2,1H3,(H2,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...				Eur J Med Chem 175: 349-356 (2019) Article DOI: 10.1016/j.ejmech.2019.04.015 BindingDB Entry DOI: 10.7270/Q21V5JC0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50524588 (CHEMBL4528373 | US10980809, Example 47) Show SMILES COCCOc1cc2ncnc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c2c2OCCOc12 Show InChI InChI=1S/C27H22F4N4O6/c1-37-8-9-38-21-13-20-22(24-23(21)39-10-11-40-24)25(33-14-32-20)41-17-5-3-16(4-6-17)34-26(36)35-19-12-15(27(29,30)31)2-7-18(19)28/h2-7,12-14H,8-11H2,1H3,(H2,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...				Eur J Med Chem 175: 349-356 (2019) Article DOI: 10.1016/j.ejmech.2019.04.015 BindingDB Entry DOI: 10.7270/Q21V5JC0
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50511899 (CHEMBL4457657 | US11045448, Cpd. No. 67) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](Cn1ccnc1CC)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C44H60FN7O5S/c1-5-41-46-20-24-50(41)31-44(34-9-6-10-35(45)25-34,39-11-7-12-40(39)47-43(54)57-4)33-18-22-49(23-19-33)26-32-27-51(28-32)36-14-16-37(17-15-36)58(55,56)38-29-52(30-38)42(53)13-8-21-48(2)3/h6,8-10,13-17,20,24-25,32-33,38-40H,5,7,11-12,18-19,21-23,26-31H2,1-4H3,(H,47,54)/b13-8+/t39-,40-,44-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay				J Med Chem 63: 4997-5010 (2020) Article DOI: 10.1021/acs.jmedchem.0c00547 BindingDB Entry DOI: 10.7270/Q2QR51G9
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50511901 (CHEMBL4528467) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN1CCCC1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C43H61FN6O5S/c1-46(2)20-8-13-41(51)50-29-38(30-50)56(53,54)37-16-14-36(15-17-37)49-27-32(28-49)26-47-23-18-33(19-24-47)43(31-48-21-4-5-22-48,34-9-6-10-35(44)25-34)39-11-7-12-40(39)45-42(52)55-3/h6,8-10,13-17,25,32-33,38-40H,4-5,7,11-12,18-24,26-31H2,1-3H3,(H,45,52)/b13-8+/t39-,40-,43-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay				J Med Chem 63: 4997-5010 (2020) Article DOI: 10.1021/acs.jmedchem.0c00547 BindingDB Entry DOI: 10.7270/Q2QR51G9
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50511912 (CHEMBL4571451) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN1CCCCC1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C44H63FN6O5S/c1-47(2)21-9-14-42(52)51-30-39(31-51)57(54,55)38-17-15-37(16-18-38)50-28-33(29-50)27-48-24-19-34(20-25-48)44(32-49-22-5-4-6-23-49,35-10-7-11-36(45)26-35)40-12-8-13-41(40)46-43(53)56-3/h7,9-11,14-18,26,33-34,39-41H,4-6,8,12-13,19-25,27-32H2,1-3H3,(H,46,53)/b14-9+/t40-,41-,44-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay				J Med Chem 63: 4997-5010 (2020) Article DOI: 10.1021/acs.jmedchem.0c00547 BindingDB Entry DOI: 10.7270/Q2QR51G9
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50511900 (CHEMBL4454017 | US11045448, Cpd. No. 72) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](Cn1ccnn1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C41H55FN8O5S/c1-46(2)19-6-11-39(51)49-27-36(28-49)56(53,54)35-14-12-34(13-15-35)48-25-30(26-48)24-47-20-16-31(17-21-47)41(29-50-22-18-43-45-50,32-7-4-8-33(42)23-32)37-9-5-10-38(37)44-40(52)55-3/h4,6-8,11-15,18,22-23,30-31,36-38H,5,9-10,16-17,19-21,24-29H2,1-3H3,(H,44,52)/b11-6+/t37-,38-,41-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay				J Med Chem 63: 4997-5010 (2020) Article DOI: 10.1021/acs.jmedchem.0c00547 BindingDB Entry DOI: 10.7270/Q2QR51G9
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50511902 (CHEMBL4553102) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN1CCC1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)C=C)CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C39H52FN5O5S/c1-3-37(46)45-25-34(26-45)51(48,49)33-13-11-32(12-14-33)44-23-28(24-44)22-42-19-15-29(16-20-42)39(27-43-17-6-18-43,30-7-4-8-31(40)21-30)35-9-5-10-36(35)41-38(47)50-2/h3-4,7-8,11-14,21,28-29,34-36H,1,5-6,9-10,15-20,22-27H2,2H3,(H,41,47)/t35-,36-,39-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay				J Med Chem 63: 4997-5010 (2020) Article DOI: 10.1021/acs.jmedchem.0c00547 BindingDB Entry DOI: 10.7270/Q2QR51G9
					More data for this Ligand-Target Pair

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