Found 25 hits for monomerid = 50113118,50113126,50113130,50113131,50113138,50113144,50121347,50228108,50228105,50228106,50228100,50228089,50228090,50228091,50228092 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50113130
(1-Benzenesulfonyl-piperidine-2-carboxylic acid phe...)Show InChI InChI=1S/C20H24N2O3S/c23-20(21-15-14-17-9-3-1-4-10-17)19-13-7-8-16-22(19)26(24,25)18-11-5-2-6-12-18/h1-6,9-12,19H,7-8,13-16H2,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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| PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12 |
Bioorg Med Chem Lett 12: 1429-33 (2002)
BindingDB Entry DOI: 10.7270/Q23J3C9S |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50113126
(1-Benzenesulfonyl-piperidine-2-carboxylic acid ben...)Show InChI InChI=1S/C19H22N2O3S/c22-19(20-15-16-9-3-1-4-10-16)18-13-7-8-14-21(18)25(23,24)17-11-5-2-6-12-17/h1-6,9-12,18H,7-8,13-15H2,(H,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12 |
Bioorg Med Chem Lett 12: 1429-33 (2002)
BindingDB Entry DOI: 10.7270/Q23J3C9S |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50113144
(1-Benzenesulfonyl-piperidine-2-carboxylic acid but...)Show InChI InChI=1S/C16H24N2O3S/c1-2-3-12-17-16(19)15-11-7-8-13-18(15)22(20,21)14-9-5-4-6-10-14/h4-6,9-10,15H,2-3,7-8,11-13H2,1H3,(H,17,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12 |
Bioorg Med Chem Lett 12: 1429-33 (2002)
BindingDB Entry DOI: 10.7270/Q23J3C9S |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50113138
(1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic ac...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCCC1C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O3S/c1-17-11-13-19(14-12-17)27(25,26)23-16-6-10-20(23)21(24)22-15-5-9-18-7-3-2-4-8-18/h2-4,7-8,11-14,20H,5-6,9-10,15-16H2,1H3,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
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| PubMed
| 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12 |
Bioorg Med Chem Lett 12: 1429-33 (2002)
BindingDB Entry DOI: 10.7270/Q23J3C9S |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50113131
(CHEMBL33413 | Pyrrolidine-1,2-dicarboxylic acid 2-...)Show InChI InChI=1S/C20H23N3O2/c24-19(21-14-13-16-8-3-1-4-9-16)18-12-7-15-23(18)20(25)22-17-10-5-2-6-11-17/h1-6,8-11,18H,7,12-15H2,(H,21,24)(H,22,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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| PubMed
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12 |
Bioorg Med Chem Lett 12: 1429-33 (2002)
BindingDB Entry DOI: 10.7270/Q23J3C9S |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50113118
(1-Benzenesulfonyl-pyrrolidine-2-carboxylic acid ph...)Show InChI InChI=1S/C19H22N2O3S/c22-19(20-14-13-16-8-3-1-4-9-16)18-12-7-15-21(18)25(23,24)17-10-5-2-6-11-17/h1-6,8-11,18H,7,12-15H2,(H,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
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| PubMed
| 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12 |
Bioorg Med Chem Lett 12: 1429-33 (2002)
BindingDB Entry DOI: 10.7270/Q23J3C9S |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| 2.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D
Curated by ChEMBL
| Assay Description Binding affinity towards cytochrome P450 2C9 |
J Med Chem 47: 907-14 (2004)
Article DOI: 10.1021/jm030972s BindingDB Entry DOI: 10.7270/Q2ZK5HF3 |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228106
(4-(2-(4-isopropylphenylthio)acetyl)morpholine-3-ca...)Show SMILES CC(C)c1ccc(SCC(=O)N2CCOCC2C(O)=O)cc1 |w:16.17| Show InChI InChI=1S/C16H21NO4S/c1-11(2)12-3-5-13(6-4-12)22-10-15(18)17-7-8-21-9-14(17)16(19)20/h3-6,11,14H,7-10H2,1-2H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
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Similars
| Article PubMed
| n/a | n/a | n/a | 4.26E+5 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228105
(2-(2-methyl-4-(pyrrolidin-1-ylsulfonyl)phenoxy)-1-...)Show InChI InChI=1S/C17H24N2O5S/c1-14-12-15(25(21,22)19-6-2-3-7-19)4-5-16(14)24-13-17(20)18-8-10-23-11-9-18/h4-5,12H,2-3,6-11,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 5.76E+5 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228108
(CHEMBL235927 | N-isopropyl-4-(2-morpholino-2-oxoet...)Show InChI InChI=1S/C15H22N2O5S/c1-12(2)16-23(19,20)14-5-3-13(4-6-14)22-11-15(18)17-7-9-21-10-8-17/h3-6,12,16H,7-11H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+ |
J Med Chem 56: 3996-4016 (2013)
Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Zn2+ |
J Med Chem 56: 3996-4016 (2013)
Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Mn2+ |
J Med Chem 56: 3996-4016 (2013)
Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z |
More data for this Ligand-Target Pair | |
Multidrug and toxin extrusion protein 1
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay |
J Med Chem 56: 781-95 (2013)
Article DOI: 10.1021/jm301302s BindingDB Entry DOI: 10.7270/Q2F76DWZ |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Heidelberg
Curated by ChEMBL
| Assay Description Inhibition of human MetAP1 |
Bioorg Med Chem Lett 20: 4038-44 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.093 BindingDB Entry DOI: 10.7270/Q2RF5W0K |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Heidelberg
Curated by ChEMBL
| Assay Description Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells |
Bioorg Med Chem Lett 20: 4038-44 (2010)
Article DOI: 10.1016/j.bmcl.2010.05.093 BindingDB Entry DOI: 10.7270/Q2RF5W0K |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| n/a | n/a | 5.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... |
Drug Metab Dispos 40: 2332-41 (2012)
Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228091
(2-(4'-methyl-biphenyl-4-yloxy)-1-morpholin-4-yl-et...)Show InChI InChI=1S/C19H21NO3/c1-15-2-4-16(5-3-15)17-6-8-18(9-7-17)23-14-19(21)20-10-12-22-13-11-20/h2-9H,10-14H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 7.55E+5 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228092
(1-(3-(trifluoromethyl)benzyl)-2-(thiazol-4-yl)-1H-...)Show InChI InChI=1S/C18H12F3N3S/c19-18(20,21)13-5-3-4-12(8-13)9-24-16-7-2-1-6-14(16)23-17(24)15-10-25-11-22-15/h1-8,10-11H,9H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | >3.00E+6 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228090
(1-morpholino-2-(p-tolylthio)ethanone | CHEMBL23638...)Show InChI InChI=1S/C13H17NO2S/c1-11-2-4-12(5-3-11)17-10-13(15)14-6-8-16-9-7-14/h2-5H,6-10H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228089
(CHEMBL393271 | N-(4-fluorophenyl)piperidine-1-sulf...)Show InChI InChI=1S/C11H15FN2O2S/c12-10-4-6-11(7-5-10)13-17(15,16)14-8-2-1-3-9-14/h4-7,13H,1-3,8-9H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 3.19E+5 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase
(Escherichia coli (strain K12)) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 472 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University
Curated by ChEMBL
| Assay Description Inhibition of Co2+ loaded MetAP expressed in Escherichia coli |
J Med Chem 49: 511-22 (2006)
Article DOI: 10.1021/jm050476z BindingDB Entry DOI: 10.7270/Q2N58KXD |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Reverse transcriptase/RNaseH
(Human immunodeficiency virus 1) | BDBM50121347
(CHEMBL625 | THIABENDAZOLE)Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Messina
Curated by ChEMBL
| Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP |
J Med Chem 45: 5410-3 (2002)
BindingDB Entry DOI: 10.7270/Q2TT4Q9K |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50228100
(1-(2,6-dimethylmorpholino)-2-(phenylthio)ethanone ...)Show InChI InChI=1S/C14H19NO2S/c1-11-8-15(9-12(2)17-11)14(16)10-18-13-6-4-3-5-7-13/h3-7,11-12H,8-10H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 7.26E+5 | n/a | n/a | n/a | n/a | n/a |
and University of California at San Diego
Curated by ChEMBL
| Assay Description Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry |
J Med Chem 50: 6607-17 (2007)
Article DOI: 10.1021/jm0707424 BindingDB Entry DOI: 10.7270/Q2TT4QPH |
More data for this Ligand-Target Pair | |