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There are 2 purchasable compounds for target: HIV-1 Integrase

Wt: 258.2
BDBM50056898
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Wt: 410.3
BDBM50055689
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056898,50055689   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Integrase


(Human immunodeficiency virus type 1)
BDBM50055689
PNG
(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Show SMILES Oc1c(C2c3ccccc3Oc3c2c(=O)oc2ccccc32)c(=O)oc2ccccc12
Show InChI InChI=1S/C25H14O6/c26-22-14-8-2-5-11-17(14)30-24(27)20(22)19-13-7-1-4-10-16(13)29-23-15-9-3-6-12-18(15)31-25(28)21(19)23/h1-12,19,26H
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.22E+5n/an/an/an/an/an/a



Institute of Pharmacy, Nirma University, Ahmedabad, 382 481, India.



Assay Description
HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.


Chem Biol Drug Des 83: 154-66 (2014)

More data for this
Ligand-Target Pair
HIV-1 Integrase


(Human immunodeficiency virus type 1)
BDBM50056898
PNG
(2-Hydroxy-benzoic acid N'-(2-hydroxy-benzyl)-hydra...)
Show SMILES Oc1ccccc1CNNC(=O)c1ccccc1O
Show InChI InChI=1S/C14H14N2O3/c17-12-7-3-1-5-10(12)9-15-16-14(19)11-6-2-4-8-13(11)18/h1-8,15,17-18H,9H2,(H,16,19)
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Institute of Pharmacy, Nirma University, Ahmedabad, 382 481, India.



Assay Description
HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.


Chem Biol Drug Des 83: 154-66 (2014)

More data for this
Ligand-Target Pair