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There are 7 purchasable compounds for target: HCV NS3 Helicase

Wt: 550.6
BDBM29331
Wt: 617.9
BDBM29332
Purchase
Wt: 424.5
BDBM29334
Purchase
Wt: 306.3
BDBM29335
Purchase
Wt: 289.3
BDBM29336
Purchase
Wt: 290.3
BDBM29337
Purchase
Wt: 346.4
BDBM29338
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 29331,29332,29334,29335,29336,29337,29338   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29331
PNG
(triphenylmethane derivative, 3)
Show SMILES Cc1cc(ccc1N)C(O)(c1ccc(Nc2ccccc2)cc1)c1ccc(Nc2ccc(cc2)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C32H29N3O4S/c1-22-21-25(11-20-31(22)33)32(36,23-7-12-27(13-8-23)34-26-5-3-2-4-6-26)24-9-14-28(15-10-24)35-29-16-18-30(19-17-29)40(37,38)39/h2-21,34-36H,33H2,1H3,(H,37,38,39)/p-1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.26E+4n/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29332
PNG
(triphenylmethane derivative, 4)
Show SMILES OC(=O)c1cc(Nc2ccc(cc2)C(Cl)(c2ccccc2)c2ccc(Nc3ccc(Cl)c(c3)C(O)=O)cc2)ccc1Cl
Show InChI InChI=1S/C33H23Cl3N2O4/c34-29-16-14-25(18-27(29)31(39)40)37-23-10-6-21(7-11-23)33(36,20-4-2-1-3-5-20)22-8-12-24(13-9-22)38-26-15-17-30(35)28(19-26)32(41)42/h1-19,37-38H,(H,39,40)(H,41,42)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.97E+4n/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29334
PNG
(triphenylmethane derivative, 6)
Show SMILES CC(C)(c1ccc(O)cc1)c1ccc(cc1)C(C)(c1ccc(O)cc1)c1ccc(O)cc1
Show InChI InChI=1S/C29H28O3/c1-28(2,21-8-14-25(30)15-9-21)20-4-6-22(7-5-20)29(3,23-10-16-26(31)17-11-23)24-12-18-27(32)19-13-24/h4-19,30-32H,1-3H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.39E+4n/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29338
PNG
(diphenol | diphenol derivative, 10)
Show SMILES CC(C)(c1ccc(O)cc1)c1ccc(cc1)C(C)(C)c1ccc(O)cc1
Show InChI InChI=1S/C24H26O2/c1-23(2,19-9-13-21(25)14-10-19)17-5-7-18(8-6-17)24(3,4)20-11-15-22(26)16-12-20/h5-16,25-26H,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 6.07E+4n/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29336
PNG
(triphenylmethane derivative, 8)
Show SMILES Nc1ccc(cc1)C(c1ccc(N)cc1)c1ccc(N)cc1
Show InChI InChI=1S/C19H19N3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,19H,20-22H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29337
PNG
(US9688816, D | triphenylmethane derivative, 9)
Show SMILES CC(c1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1
Show InChI InChI=1S/C20H18O2/c1-20(15-5-3-2-4-6-15,16-7-11-18(21)12-8-16)17-9-13-19(22)14-10-17/h2-14,21-22H,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair
HCV NS3 Helicase


(Hepatitis C virus genotype 1b (isolate Taiwan))
BDBM29335
PNG
(triphenylmethane derivative, 7)
Show SMILES CC(c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(O)cc1
Show InChI InChI=1S/C20H18O3/c1-20(14-2-8-17(21)9-3-14,15-4-10-18(22)11-5-15)16-6-12-19(23)13-7-16/h2-13,21-23H,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...


J Med Chem 52: 2716-23 (2009)

More data for this
Ligand-Target Pair