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There are 167 purchasable compounds for target: Kallikrein 7

Wt: 310.2
BDBM29681
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Wt: 279.2
BDBM32709
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Wt: 352.3
BDBM33200
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Wt: 299.7
BDBM33882
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Wt: 324.3
BDBM33437
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Wt: 218.2
BDBM33453
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Wt: 345.3
BDBM38923
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Wt: 468.5
BDBM42369
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Wt: 442.4
BDBM50549
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Wt: 263.2
BDBM49521
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Wt: 364.4
BDBM52678
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Wt: 378.4
BDBM52680
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Wt: 367.4
BDBM51528
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Wt: 465.4
BDBM52033
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Wt: 397.2
BDBM51549
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Displayed 1 to 15 (of 167 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 29681,32709,33200,33882,33437,33453,38923,42369,50549,49521,52678,52680,51528,52033,51549   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 7


(Homo sapiens (Human))
BDBM33453
PNG
((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Show SMILES COc1ccc(cc1)C(=O)n1cnnc1N
Show InChI InChI=1S/C10H10N4O2/c1-16-8-4-2-7(3-5-8)9(15)14-6-12-13-10(14)11/h2-6H,1H3,(H2,11,13)
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n/an/a 610n/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assay


Bioorg Med Chem Lett 23: 4547-51 (2013)

More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM42369
PNG
(1-(3-ethoxypropyl)-2-imino-10-methyl-N-(2-morpholi...)
Show SMILES CCOCCCn1c2nc3c(C)cccn3c(=O)c2cc(C(=O)NCCN2CCOCC2)c1=N
Show InChI InChI=1S/C24H32N6O4/c1-3-33-13-5-9-29-20(25)18(23(31)26-7-10-28-11-14-34-15-12-28)16-19-22(29)27-21-17(2)6-4-8-30(21)24(19)32/h4,6,8,16,25H,3,5,7,9-15H2,1-2H3,(H,26,31)
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n/an/an/an/a>6.95E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM33882
PNG
((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Show SMILES Nc1nc(nn1C(=O)c1ccc(Cl)cc1)-c1cccnc1
Show InChI InChI=1S/C14H10ClN5O/c15-11-5-3-9(4-6-11)13(21)20-14(16)18-12(19-20)10-2-1-7-17-8-10/h1-8H,(H2,16,18,19)
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n/an/a 220n/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assay


Bioorg Med Chem Lett 23: 4547-51 (2013)

More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM32709
PNG
((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Show SMILES Cc1ccc(cc1)C(=O)n1nc(nc1N)-c1cccnc1
Show InChI InChI=1S/C15H13N5O/c1-10-4-6-11(7-5-10)14(21)20-15(16)18-13(19-20)12-3-2-8-17-9-12/h2-9H,1H3,(H2,16,18,19)
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n/an/a 40n/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assay


Bioorg Med Chem Lett 23: 4547-51 (2013)

More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM49521
PNG
(4-methyl-N-(6-quinoxalinyl)benzamide | 4-methyl-N-...)
Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc2nccnc2c1
Show InChI InChI=1S/C16H13N3O/c1-11-2-4-12(5-3-11)16(20)19-13-6-7-14-15(10-13)18-9-8-17-14/h2-10H,1H3,(H,19,20)
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n/an/an/an/a 9.72E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM29681
PNG
(2-[(1,2,3,4-tetrafluoro-9-acridinyl)amino]ethanol ...)
Show SMILES OCCNc1c2ccccc2nc2c(F)c(F)c(F)c(F)c12
Show InChI InChI=1S/C15H10F4N2O/c16-10-9-14(20-5-6-22)7-3-1-2-4-8(7)21-15(9)13(19)12(18)11(10)17/h1-4,22H,5-6H2,(H,20,21)
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n/an/an/an/a>6.95E+4n/an/an/an/a



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Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM52678
PNG
((2Z)-2-[(4-methylphenyl)methylidene]-7-[(4-methylp...)
Show SMILES CN1CCN(Cc2c3O\C(=C/c4ccc(C)cc4)C(=O)c3ccc2O)CC1
Show InChI InChI=1S/C22H24N2O3/c1-15-3-5-16(6-4-15)13-20-21(26)17-7-8-19(25)18(22(17)27-20)14-24-11-9-23(2)10-12-24/h3-8,13,25H,9-12,14H2,1-2H3/b20-13-
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n/an/an/an/a 1.25E+4n/an/an/an/a



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Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM52680
PNG
((2Z)-7-[(4-ethyl-1-piperazinyl)methyl]-6-hydroxy-2...)
Show SMILES CCN1CCN(Cc2c3O\C(=C/c4ccc(C)cc4)C(=O)c3ccc2O)CC1
Show InChI InChI=1S/C23H26N2O3/c1-3-24-10-12-25(13-11-24)15-19-20(26)9-8-18-22(27)21(28-23(18)19)14-17-6-4-16(2)5-7-17/h4-9,14,26H,3,10-13,15H2,1-2H3/b21-14-
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n/an/an/an/a 2.39E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM50549
PNG
(2-(5-methyl-2-furanyl)-4-quinolinecarboxylic acid ...)
Show SMILES CN(C1CCS(=O)(=O)C1)C(=O)COC(=O)c1cc(nc2ccccc12)-c1ccc(C)o1
Show InChI InChI=1S/C22H22N2O6S/c1-14-7-8-20(30-14)19-11-17(16-5-3-4-6-18(16)23-19)22(26)29-12-21(25)24(2)15-9-10-31(27,28)13-15/h3-8,11,15H,9-10,12-13H2,1-2H3
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n/an/an/an/a 6.97E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM33200
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid [2-(dieth...)
Show SMILES CCN(CC)C(=O)COC(=O)c1cc(nc2ccccc12)-c1ccco1
Show InChI InChI=1S/C20H20N2O4/c1-3-22(4-2)19(23)13-26-20(24)15-12-17(18-10-7-11-25-18)21-16-9-6-5-8-14(15)16/h5-12H,3-4,13H2,1-2H3
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n/an/an/an/a 2.30E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM52033
PNG
((2S)-2-[[1-oxo-2-[(4,8,8-trimethyl-2-oxo-9,10-dihy...)
Show SMILES Cc1cc(=O)oc2c3CCC(C)(C)Oc3cc(OCC(=O)N[C@@H](Cc3ccccc3)C(O)=O)c12
Show InChI InChI=1S/C26H27NO7/c1-15-11-22(29)33-24-17-9-10-26(2,3)34-19(17)13-20(23(15)24)32-14-21(28)27-18(25(30)31)12-16-7-5-4-6-8-16/h4-8,11,13,18H,9-10,12,14H2,1-3H3,(H,27,28)(H,30,31)/t18-/m0/s1
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n/an/an/an/a 4.90E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM51549
PNG
(5-bromanyl-N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-met...)
Show SMILES Cc1ccc(cc1NC(=O)c1ccc(Br)o1)-c1cn2cccnc2n1
Show InChI InChI=1S/C18H13BrN4O2/c1-11-3-4-12(14-10-23-8-2-7-20-18(23)22-14)9-13(11)21-17(24)15-5-6-16(19)25-15/h2-10H,1H3,(H,21,24)
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Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM38923
PNG
((2-oxidanylideneoxolan-3-yl) 5-(1,3-benzothiazol-2...)
Show SMILES O=C(OC1CCOC1=O)c1ccc(s1)-c1nc2ccccc2s1
Show InChI InChI=1S/C16H11NO4S2/c18-15-10(7-8-20-15)21-16(19)13-6-5-12(22-13)14-17-9-3-1-2-4-11(9)23-14/h1-6,10H,7-8H2
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The Scripps Research Institute Molecular Screening Center

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Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM51528
PNG
(2-amino-1-(2-piperidinoethyl)pyrrolo[3,2-b]quinoxa...)
Show SMILES CCOC(=O)c1c(N)n(CCN2CCCCC2)c2nc3ccccc3nc12
Show InChI InChI=1S/C20H25N5O2/c1-2-27-20(26)16-17-19(23-15-9-5-4-8-14(15)22-17)25(18(16)21)13-12-24-10-6-3-7-11-24/h4-5,8-9H,2-3,6-7,10-13,21H2,1H3
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n/an/an/an/a 3.62E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM33437
PNG
((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)
Show SMILES COc1ccc(cc1OC)C(=O)n1nc(nc1N)-c1ccccc1
Show InChI InChI=1S/C17H16N4O3/c1-23-13-9-8-12(10-14(13)24-2)16(22)21-17(18)19-15(20-21)11-6-4-3-5-7-11/h3-10H,1-2H3,(H2,18,19,20)
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n/an/a 230n/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assay


Bioorg Med Chem Lett 23: 4547-51 (2013)

More data for this
Ligand-Target Pair