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There are 3 purchasable compounds for target: Carnitine palmitoyltransferase 1A

Wt: 543.5
BDBM22984
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Wt: 277.4
BDBM61402
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Wt: 186.2
BDBM50025259
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22984,61402,50025259   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carnitine palmitoyltransferase 1A


(Sus scrofa)
BDBM50025259
PNG
(2-Hexyl-oxirane-2-carboxylic acid methyl ester | C...)
Show SMILES CCCCCCC1(CO1)C(=O)OC
Show InChI InChI=1S/C10H18O3/c1-3-4-5-6-7-10(8-13-10)9(11)12-2/h3-8H2,1-2H3
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.36E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for its inhibitory activity against carnitine palmitoyl transferase-A (CPT-A)


Citation and Details
More data for this
Ligand-Target Pair
Carnitine palmitoyltransferase 1A


(Rattus norvegicus)
BDBM61402
PNG
((Z)-2-butenedioic acid;2-(2,2-dicyclohexylethyl)pi...)
Show SMILES C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1
Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2
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KEGG

UniProtKB/SwissProt

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CHEMBL
DrugBank
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.70E+4n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of CPT1 in rat cardiac mitochondria using [3H]carnitine by radiometric method


J Med Chem 54: 3109-52 (2011)

More data for this
Ligand-Target Pair
Carnitine palmitoyltransferase 1A


(Rattus norvegicus)
BDBM61402
PNG
((Z)-2-butenedioic acid;2-(2,2-dicyclohexylethyl)pi...)
Show SMILES C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1
Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2
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KEGG

UniProtKB/SwissProt

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CHEMBL
DrugBank
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.48E+5n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of CPT1 in rat liver mitochondria using [3H]carnitine by radiometric method


J Med Chem 54: 3109-52 (2011)

More data for this
Ligand-Target Pair
Carnitine palmitoyltransferase 1A


(Rattus norvegicus)
BDBM22984
PNG
((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
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KEGG

UniProtKB/SwissProt

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CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Article
PubMed
n/an/a 2.50E+5n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat CPT1 in rat mitochondria


J Med Chem 54: 3109-52 (2011)

More data for this
Ligand-Target Pair