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There are 2 purchasable compounds for target: Peptidylglycine alpha-hydroxylating monooxygenase

Wt: 118.0
BDBM82195
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Wt: 194.2
BDBM50288771
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82195,50288771   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptidyl-glycine alpha-amidating monooxygenase


(Homo sapiens (Human))
BDBM50288771
PNG
(((E)-Styrylsulfanyl)-acetic acid | CHEMBL127222)
Show SMILES OC(=O)CS\C=C\c1ccccc1
Show InChI InChI=1S/C10H10O2S/c11-10(12)8-13-7-6-9-4-2-1-3-5-9/h1-7H,8H2,(H,11,12)/b7-6+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
0.100n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for inhibition of peptidylglycine alpha hydroxylating monooxygenase (PHM) was determined


Bioorg Med Chem Lett 6: 393-396 (1996)

More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Homo sapiens (Human))
BDBM82195
PNG
(Substrate analogue, 13)
Show SMILES CC(=O)OCC(O)=O
Show InChI InChI=1S/C4H6O4/c1-3(5)8-2-4(6)7/h2H2,1H3,(H,6,7)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.10E+6n/an/an/an/an/an/a



Australian National University

Curated by ChEMBL


Assay Description
Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysis


Bioorg Med Chem Lett 22: 7015-8 (2012)

More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Homo sapiens (Human))
BDBM82195
PNG
(Substrate analogue, 13)
Show SMILES CC(=O)OCC(O)=O
Show InChI InChI=1S/C4H6O4/c1-3(5)8-2-4(6)7/h2H2,1H3,(H,6,7)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.10E+6n/an/an/an/an/an/a



Australian National University

Curated by ChEMBL


Assay Description
Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysis


Bioorg Med Chem Lett 22: 7015-8 (2012)

More data for this
Ligand-Target Pair