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There are 4 purchasable compounds for target: p53-induced protein phosphatase 1

Wt: 326.3
BDBM50046578
Purchase
Wt: 308.3
BDBM50046583
Purchase
Wt: 294.3
BDBM50046668
Purchase
Wt: 312.3
BDBM50046669
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046578,50046583,50046668,50046669   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein phosphatase 1D


(Homo sapiens (Human))
BDBM50046578
PNG
(CHEMBL3314464)
Show SMILES Cc1cc(ccc1F)-c1nc(cs1)-c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C17H11FN2O2S/c1-9-6-11(2-4-12(9)18)16-19-14(8-23-16)10-3-5-13-15(7-10)22-17(21)20-13/h2-8H,1H3,(H,20,21)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a<2.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PPM1D (unknown origin) phosphatase activity using peptide substrate TDDEMT*GY*VAT by malachite green/molybdate based assay


Bioorg Med Chem Lett 24: 3469-74 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.067
More data for this
Ligand-Target Pair
Protein phosphatase 1D


(Homo sapiens (Human))
BDBM50046669
PNG
(CHEMBL3314456)
Show SMILES Fc1ccc(cc1)-c1nc(cs1)-c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C16H9FN2O2S/c17-11-4-1-9(2-5-11)15-18-13(8-22-15)10-3-6-12-14(7-10)21-16(20)19-12/h1-8H,(H,19,20)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PPM1D (unknown origin) phosphatase activity using peptide substrate TDDEMT*GY*VAT by malachite green/molybdate based assay


Bioorg Med Chem Lett 24: 3469-74 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.067
More data for this
Ligand-Target Pair
Protein phosphatase 1D


(Homo sapiens (Human))
BDBM50046668
PNG
(CHEMBL3314457)
Show SMILES O=c1[nH]c2ccc(cc2o1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C16H10N2O2S/c19-16-18-12-7-6-11(8-14(12)20-16)13-9-21-15(17-13)10-4-2-1-3-5-10/h1-9H,(H,18,19)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a<2.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PPM1D (unknown origin) phosphatase activity using peptide substrate TDDEMT*GY*VAT by malachite green/molybdate based assay


Bioorg Med Chem Lett 24: 3469-74 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.067
More data for this
Ligand-Target Pair
Protein phosphatase 1D


(Homo sapiens (Human))
BDBM50046583
PNG
(CHEMBL3314459)
Show SMILES Cc1ccc(cc1)-c1nc(cs1)-c1ccc2[nH]c(=O)oc2c1
Show InChI InChI=1S/C17H12N2O2S/c1-10-2-4-11(5-3-10)16-18-14(9-22-16)12-6-7-13-15(8-12)21-17(20)19-13/h2-9H,1H3,(H,19,20)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a<2.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PPM1D (unknown origin) phosphatase activity using peptide substrate TDDEMT*GY*VAT by malachite green/molybdate based assay


Bioorg Med Chem Lett 24: 3469-74 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.067
More data for this
Ligand-Target Pair