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There are 13 purchasable compounds for target: PACAP type II receptor

Wt: 282.3
BDBM50241256
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Wt: 220.2
BDBM50365987
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Wt: 234.3
BDBM50365988
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Wt: 248.3
BDBM50365989
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Wt: 262.3
BDBM50365990
Wt: 246.3
BDBM50365991
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Wt: 274.3
BDBM50365993
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Wt: 288.4
BDBM50365994
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Wt: 296.3
BDBM50365995
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Wt: 310.4
BDBM50365996
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Wt: 324.4
BDBM50365999
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Wt: 340.4
BDBM50366001
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Wt: 312.3
BDBM50366008
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50241256,50365987,50365988,50365989,50365990,50365991,50365993,50365994,50365995,50365996,50365999,50366001,50366008   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365987
PNG
(CHEMBL1412798)
Show SMILES CC(=O)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C11H12N2OS/c1-7(14)13-11-9(6-12)8-4-2-3-5-10(8)15-11/h2-5H2,1H3,(H,13,14)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365988
PNG
(CHEMBL1956428)
Show SMILES CCC(=O)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C12H14N2OS/c1-2-11(15)14-12-9(7-13)8-5-3-4-6-10(8)16-12/h2-6H2,1H3,(H,14,15)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365989
PNG
(CHEMBL1632048)
Show SMILES CC(C)C(=O)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C13H16N2OS/c1-8(2)12(16)15-13-10(7-14)9-5-3-4-6-11(9)17-13/h8H,3-6H2,1-2H3,(H,15,16)
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n/an/a 3.40E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365990
PNG
(CHEMBL1956429)
Show SMILES CC(C)CC(=O)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C14H18N2OS/c1-9(2)7-13(17)16-14-11(8-15)10-5-3-4-6-12(10)18-14/h9H,3-7H2,1-2H3,(H,16,17)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365991
PNG
(CHEMBL1956430)
Show SMILES O=C(Nc1sc2CCCCc2c1C#N)C1CC1
Show InChI InChI=1S/C13H14N2OS/c14-7-10-9-3-1-2-4-11(9)17-13(10)15-12(16)8-5-6-8/h8H,1-6H2,(H,15,16)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365993
PNG
(CHEMBL1956432)
Show SMILES O=C(Nc1sc2CCCCc2c1C#N)C1CCCC1
Show InChI InChI=1S/C15H18N2OS/c16-9-12-11-7-3-4-8-13(11)19-15(12)17-14(18)10-5-1-2-6-10/h10H,1-8H2,(H,17,18)
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PC cid
PC sid
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Article
PubMed
n/an/a 470n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50366008
PNG
(CHEMBL1956445)
Show SMILES O=C(COc1ccccc1)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C17H16N2O2S/c18-10-14-13-8-4-5-9-15(13)22-17(14)19-16(20)11-21-12-6-2-1-3-7-12/h1-3,6-7H,4-5,8-9,11H2,(H,19,20)
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n/an/a 9.10E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50241256
PNG
(CHEMBL233000 | N-(3-cyano-4,5,6,7-tetrahydrobenzo[...)
Show SMILES O=C(Nc1sc2CCCCc2c1C#N)c1ccccc1
Show InChI InChI=1S/C16H14N2OS/c17-10-13-12-8-4-5-9-14(12)20-16(13)18-15(19)11-6-2-1-3-7-11/h1-3,6-7H,4-5,8-9H2,(H,18,19)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365995
PNG
(CHEMBL397167)
Show SMILES O=C(Cc1ccccc1)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C17H16N2OS/c18-11-14-13-8-4-5-9-15(13)21-17(14)19-16(20)10-12-6-2-1-3-7-12/h1-3,6-7H,4-5,8-10H2,(H,19,20)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365996
PNG
(CHEMBL1956433)
Show SMILES O=C(CCc1ccccc1)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C18H18N2OS/c19-12-15-14-8-4-5-9-16(14)22-18(15)20-17(21)11-10-13-6-2-1-3-7-13/h1-3,6-7H,4-5,8-11H2,(H,20,21)
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n/an/a 290n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365999
PNG
(CHEMBL1956436)
Show SMILES Cc1ccc(CCC(=O)Nc2sc3CCCCc3c2C#N)cc1
Show InChI InChI=1S/C19H20N2OS/c1-13-6-8-14(9-7-13)10-11-18(22)21-19-16(12-20)15-4-2-3-5-17(15)23-19/h6-9H,2-5,10-11H2,1H3,(H,21,22)
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n/an/a 480n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50366001
PNG
(CHEMBL1956438)
Show SMILES COc1ccc(CCC(=O)Nc2sc3CCCCc3c2C#N)cc1
Show InChI InChI=1S/C19H20N2O2S/c1-23-14-9-6-13(7-10-14)8-11-18(22)21-19-16(12-20)15-4-2-3-5-17(15)24-19/h6-7,9-10H,2-5,8,11H2,1H3,(H,21,22)
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n/an/a 410n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair
Vasoactive intestinal polypeptide receptor 1


(Rattus norvegicus)
BDBM50365994
PNG
(CHEMBL396627)
Show SMILES O=C(Nc1sc2CCCCc2c1C#N)C1CCCCC1
Show InChI InChI=1S/C16H20N2OS/c17-10-13-12-8-4-5-9-14(12)20-16(13)18-15(19)11-6-2-1-3-7-11/h11H,1-9H2,(H,18,19)
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PubMed
n/an/a 470n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...


Bioorg Med Chem Lett 22: 2287-90 (2012)

More data for this
Ligand-Target Pair