Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'CviR transcriptional regulator'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50351516 (CHEMBL1823953) Show SMILES Clc1ccc(OCCCC(=O)NC2CCOC2=O)cc1 Show InChI InChI=1S/C14H16ClNO4/c15-10-3-5-11(6-4-10)19-8-1-2-13(17)16-12-7-9-20-14(12)18/h3-6,12H,1-2,7-9H2,(H,16,17)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Chromobacterium violaceum CviR-dependent GFP fluorescence in Escherichia coli				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair				3D Structure (crystal)
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50136221 (CHEMBL3754734) Show SMILES O=C(COc1ccc(cc1)C1=NCCN1)Nc1ccccc1 |t:11| Show InChI InChI=1S/C17H17N3O2/c21-16(20-14-4-2-1-3-5-14)12-22-15-8-6-13(7-9-15)17-18-10-11-19-17/h1-9H,10-12H2,(H,18,19)(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Polit£cnico Nacional Curated by ChEMBL					Assay Description Inhibition of CviR in Chromobacterium violaceum CV026 assessed as reduction of violacein production after 15 hrs				Bioorg Med Chem 23: 7565-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.046 BindingDB Entry DOI: 10.7270/Q2RF5WVS
					More data for this Ligand-Target Pair
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50136219 (CHEMBL3753564) Show SMILES CCCCCCOc1ccc(cc1)C1=NCCN1 |t:14| Show InChI InChI=1S/C15H22N2O/c1-2-3-4-5-12-18-14-8-6-13(7-9-14)15-16-10-11-17-15/h6-9H,2-5,10-12H2,1H3,(H,16,17)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Polit£cnico Nacional Curated by ChEMBL					Assay Description Inhibition of CviR in Chromobacterium violaceum CV026 assessed as reduction of violacein production after 15 hrs				Bioorg Med Chem 23: 7565-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.046 BindingDB Entry DOI: 10.7270/Q2RF5WVS
					More data for this Ligand-Target Pair
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50136296 (CHEMBL3754531) Show SMILES CCCCCCOc1ccc(cc1)C1=NCCO1 |t:14| Show InChI InChI=1S/C15H21NO2/c1-2-3-4-5-11-17-14-8-6-13(7-9-14)15-16-10-12-18-15/h6-9H,2-5,10-12H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Polit£cnico Nacional Curated by ChEMBL					Assay Description Inhibition of CviR in Chromobacterium violaceum CV026 assessed as reduction of violacein production after 15 hrs				Bioorg Med Chem 23: 7565-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.046 BindingDB Entry DOI: 10.7270/Q2RF5WVS
					More data for this Ligand-Target Pair
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50136220 (CHEMBL3752577) Show SMILES COc1ccc(NC(=O)COc2ccc(cc2)C2=NCCN2)cc1 |t:18| Show InChI InChI=1S/C18H19N3O3/c1-23-15-8-4-14(5-9-15)21-17(22)12-24-16-6-2-13(3-7-16)18-19-10-11-20-18/h2-9H,10-12H2,1H3,(H,19,20)(H,21,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Polit£cnico Nacional Curated by ChEMBL					Assay Description Inhibition of CviR in Chromobacterium violaceum CV026 assessed as reduction of violacein production after 15 hrs				Bioorg Med Chem 23: 7565-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.046 BindingDB Entry DOI: 10.7270/Q2RF5WVS
					More data for this Ligand-Target Pair
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50136222 (CHEMBL3754036) Show SMILES O=C(Cc1ccccc1)NC1=NCCS1 |t:11| Show InChI InChI=1S/C11H12N2OS/c14-10(13-11-12-6-7-15-11)8-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,13,14)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Polit£cnico Nacional Curated by ChEMBL					Assay Description Inhibition of CviR in Chromobacterium violaceum CV026 assessed as reduction of violacein production after 15 hrs				Bioorg Med Chem 23: 7565-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.046 BindingDB Entry DOI: 10.7270/Q2RF5WVS
					More data for this Ligand-Target Pair