Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'Deoxyuridine triphosphatase, putative'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186267 (2'-deoxy-5'-uridylic acid | CHEMBL211312 | dUMP) Show SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H13N2O8P/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186257 ((S)-5-amino-2-((S)-2-(2-(2,4-dioxo-3,4-dihydropyri...) Show SMILES C[C@H](NC(=O)Cn1ccc(=O)[nH]c1=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O Show InChI InChI=1S/C14H19N5O7/c1-7(12(23)17-8(13(24)25)2-3-9(15)20)16-11(22)6-19-5-4-10(21)18-14(19)26/h4-5,7-8H,2-3,6H2,1H3,(H2,15,20)(H,16,22)(H,17,23)(H,24,25)(H,18,21,26)/t7-,8-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186259 ((S)-6-amino-2-(2-(2-(2,4-dioxo-3,4-dihydropyrimidi...) Show SMILES NCCCC[C@H](NC(=O)CNC(=O)Cn1ccc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C14H21N5O6/c15-5-2-1-3-9(13(23)24)17-11(21)7-16-12(22)8-19-6-4-10(20)18-14(19)25/h4,6,9H,1-3,5,7-8,15H2,(H,16,22)(H,17,21)(H,23,24)(H,18,20,25)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186260 ((2S,3R)-2-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(...) Show SMILES CC(O)[C@H](NC(=O)CNC(=O)Cn1ccc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C12H16N4O7/c1-6(17)10(11(21)22)14-8(19)4-13-9(20)5-16-3-2-7(18)15-12(16)23/h2-3,6,10,17H,4-5H2,1H3,(H,13,20)(H,14,19)(H,21,22)(H,15,18,23)/t6?,10-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186261 ((S)-6-amino-2-((S)-2-(2-(2,4-dioxo-3,4-dihydropyri...) Show SMILES C[C@H](NC(=O)Cn1ccc(=O)[nH]c1=O)C(=O)N[C@@H](CCCCN)C(O)=O Show InChI InChI=1S/C15H23N5O6/c1-9(13(23)18-10(14(24)25)4-2-3-6-16)17-12(22)8-20-7-5-11(21)19-15(20)26/h5,7,9-10H,2-4,6,8,16H2,1H3,(H,17,22)(H,18,23)(H,24,25)(H,19,21,26)/t9-,10-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186265 ((S)-2-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-...) Show SMILES C[C@H](NC(=O)Cn1ccc(=O)[nH]c1=O)C(=O)NCC(O)=O Show InChI InChI=1S/C11H14N4O6/c1-6(10(20)12-4-9(18)19)13-8(17)5-15-3-2-7(16)14-11(15)21/h2-3,6H,4-5H2,1H3,(H,12,20)(H,13,17)(H,18,19)(H,14,16,21)/t6-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186262 ((S)-2-((S)-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(...) Show SMILES C[C@H](NC(=O)Cn1ccc(=O)[nH]c1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C14H18N4O8/c1-7(12(23)16-8(13(24)25)2-3-11(21)22)15-10(20)6-18-5-4-9(19)17-14(18)26/h4-5,7-8H,2-3,6H2,1H3,(H,15,20)(H,16,23)(H,21,22)(H,24,25)(H,17,19,26)/t7-,8-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186266 ((2S,3R)-2-((S)-2-(2-(2,4-dioxo-3,4-dihydropyrimidi...) Show SMILES CC(O)[C@H](NC(=O)[C@H](C)NC(=O)Cn1ccc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C13H18N4O7/c1-6(11(21)16-10(7(2)18)12(22)23)14-9(20)5-17-4-3-8(19)15-13(17)24/h3-4,6-7,10,18H,5H2,1-2H3,(H,14,20)(H,16,21)(H,22,23)(H,15,19,24)/t6-,7?,10-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186258 ((S)-2-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-...) Show SMILES OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)Cn1ccc(=O)[nH]c1=O Show InChI InChI=1S/C17H18N4O7/c22-11-3-1-10(2-4-11)7-12(16(26)27)19-14(24)8-18-15(25)9-21-6-5-13(23)20-17(21)28/h1-6,12,22H,7-9H2,(H,18,25)(H,19,24)(H,26,27)(H,20,23,28)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186263 ((S)-2-((S)-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(...) Show SMILES C[C@H](NC(=O)Cn1ccc(=O)[nH]c1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C18H20N4O7/c1-10(19-15(25)9-22-7-6-14(24)21-18(22)29)16(26)20-13(17(27)28)8-11-2-4-12(23)5-3-11/h2-7,10,13,23H,8-9H2,1H3,(H,19,25)(H,20,26)(H,27,28)(H,21,24,29)/t10-,13-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186256 ((S)-2-((S)-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(...) Show SMILES C[C@H](NC(=O)Cn1ccc(=O)[nH]c1=O)C(=O)N[C@@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C13H16N4O8/c1-6(11(22)15-7(12(23)24)4-10(20)21)14-9(19)5-17-3-2-8(18)16-13(17)25/h2-3,6-7H,4-5H2,1H3,(H,14,19)(H,15,22)(H,20,21)(H,23,24)(H,16,18,25)/t6-,7-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair
Deoxyuridine triphosphatase, putative (Trypanosoma cruzi)	BDBM50186264 (2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acet...) Show SMILES OC(=O)CNC(=O)Cn1ccc(=O)[nH]c1=O Show InChI InChI=1S/C8H9N3O5/c12-5-1-2-11(8(16)10-5)4-6(13)9-3-7(14)15/h1-2H,3-4H2,(H,9,13)(H,14,15)(H,10,12,16)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi dUTPase at 1 mM				Bioorg Med Chem Lett 16: 3809-12 (2006) Article DOI: 10.1016/j.bmcl.2006.04.027 BindingDB Entry DOI: 10.7270/Q21C1WG4
					More data for this Ligand-Target Pair