Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Glutamate--cysteine ligase catalytic subunit'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human))	BDBM50366432 (CHEMBL1627263) Show SMILES CCC(CS(=N)(=O)CCC(=N)C(O)=O)C(O)=O Show InChI InChI=1S/C9H18N2O5S/c1-2-6(8(12)13)5-17(11,16)4-3-7(10)9(14)15/h6,10,17H,2-5H2,1H3,(H2,11,16)(H,12,13)(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.1 uM				Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4
					More data for this Ligand-Target Pair
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human))	BDBM50287274 ((2S)-2-ammonio-4-[(2-carboxylatobutyl)phosphinato]...) Show SMILES CCC(CP([O-])(=O)CC[C@H]([NH3+])C([O-])=O)C([O-])=O Show InChI InChI=1S/C9H18NO6P/c1-2-6(8(11)12)5-17(15,16)4-3-7(10)9(13)14/h6-7H,2-5,10H2,1H3,(H,11,12)(H,13,14)(H,15,16)/p-2/t6?,7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	4.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.7 uM				Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4
					More data for this Ligand-Target Pair
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human))	BDBM50287275 (2-ammonio-4-[(2-carboxylatobutyl)sulfonyl]butanoat...) Show SMILES CCC(CS(=O)(=O)CCC([NH3+])C([O-])=O)C([O-])=O Show InChI InChI=1S/C9H17NO6S/c1-2-6(8(11)12)5-17(15,16)4-3-7(10)9(13)14/h6-7H,2-5,10H2,1H3,(H,11,12)(H,13,14)/p-1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	9.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 16.3 uM				Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4
					More data for this Ligand-Target Pair
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human))	BDBM50366433 (CHEMBL1609891) Show SMILES CCCCS(=N)(=O)CCC(=N)C(O)=O Show InChI InChI=1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h9,14H,2-6H2,1H3,(H2,10,13)(H,11,12)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4.93E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 25.0 uM				Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4
					More data for this Ligand-Target Pair
Glutamate--cysteine ligase catalytic subunit (Rattus norvegicus)	BDBM50487312 (BUTHIONINE SULFOXIME) Show SMILES CCCCS(=N)(=O)CC[C@H](N)C(O)=O Show InChI InChI=1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	Article	1.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Rattus norvegicus Wistar (rat) rat glutamate cysteine ligase using glutamate as substrate incubated for 10 min prior to substrate addit...				Citation and Details Article DOI: 10.1007/s00044-004-0112-9 BindingDB Entry DOI: 10.7270/Q28S4STT
					More data for this Ligand-Target Pair