Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with Target = 'Glucose-6-phosphatase catalytic subunit 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103118 (CHEMBL66059 | N,N-Dibenzyl-N'-[1-(5-chloro-thiophe...) Show SMILES Clc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)s1 Show InChI InChI=1S/C19H17ClN2S/c20-19-12-11-18(23-19)13-21-22(14-16-7-3-1-4-8-16)15-17-9-5-2-6-10-17/h1-13H,14-15H2/b21-13+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103125 (CHEMBL69115 | N,N-Dibenzyl-N'-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)cc1 Show InChI InChI=1S/C22H22N2O/c1-25-22-14-12-19(13-15-22)16-23-24(17-20-8-4-2-5-9-20)18-21-10-6-3-7-11-21/h2-16H,17-18H2,1H3/b23-16+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103111 (CHEMBL69665 | N,N-Dibenzyl-N'-[1-(4-chloro-phenyl)...) Show SMILES Clc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)cc1 Show InChI InChI=1S/C21H19ClN2/c22-21-13-11-18(12-14-21)15-23-24(16-19-7-3-1-4-8-19)17-20-9-5-2-6-10-20/h1-15H,16-17H2/b23-15+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103119 (CHEMBL302504 | N,N-Dibenzyl-N'-[1-(5-ethyl-furan-2...) Show SMILES CCc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)o1 Show InChI InChI=1S/C21H22N2O/c1-2-20-13-14-21(24-20)15-22-23(16-18-9-5-3-6-10-18)17-19-11-7-4-8-12-19/h3-15H,2,16-17H2,1H3/b22-15+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103107 (CHEMBL65842 | N,N-Dibenzyl-N'-[1-(3-methoxy-phenyl...) Show SMILES COc1cccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)c1 Show InChI InChI=1S/C22H22N2O/c1-25-22-14-8-13-21(15-22)16-23-24(17-19-9-4-2-5-10-19)18-20-11-6-3-7-12-20/h2-16H,17-18H2,1H3/b23-16+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103128 (CHEMBL68984 | N,N-Dibenzyl-N'-[1-furan-2-yl-meth-(...) Show SMILES C(N(Cc1ccccc1)\N=C\c1ccco1)c1ccccc1 Show InChI InChI=1S/C19H18N2O/c1-3-8-17(9-4-1)15-21(16-18-10-5-2-6-11-18)20-14-19-12-7-13-22-19/h1-14H,15-16H2/b20-14+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103106 (CHEMBL69480 | N,N-Dibenzyl-N'-[1-thiophen-2-yl-met...) Show SMILES C(N(Cc1ccccc1)\N=C\c1cccs1)c1ccccc1 Show InChI InChI=1S/C19H18N2S/c1-3-8-17(9-4-1)15-21(16-18-10-5-2-6-11-18)20-14-19-12-7-13-22-19/h1-14H,15-16H2/b20-14+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103122 (CHEMBL69334 | N,N-Dibenzyl-N'-[1-phenyl-meth-(E)-y...) Show SMILES C(N(Cc1ccccc1)\N=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H20N2/c1-4-10-19(11-5-1)16-22-23(17-20-12-6-2-7-13-20)18-21-14-8-3-9-15-21/h1-16H,17-18H2/b22-16+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103110 (CHEMBL305258 | N,N-Dibenzyl-N'-[1-(3,4-dichloro-ph...) Show SMILES Clc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)cc1Cl Show InChI InChI=1S/C21H18Cl2N2/c22-20-12-11-19(13-21(20)23)14-24-25(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14H,15-16H2/b24-14+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103114 (CHEMBL69541 | N,N-Dibenzyl-N'-[1-cyclohexyl-meth-(...) Show SMILES C(N(Cc1ccccc1)N=CC1CCCCC1)c1ccccc1 |w:10.11| Show InChI InChI=1S/C21H26N2/c1-4-10-19(11-5-1)16-22-23(17-20-12-6-2-7-13-20)18-21-14-8-3-9-15-21/h2-3,6-9,12-16,19H,1,4-5,10-11,17-18H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103115 (4-(Dibenzyl-hydrazonomethyl)-phenol | CHEMBL70032) Show SMILES Oc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)cc1 Show InChI InChI=1S/C21H20N2O/c24-21-13-11-18(12-14-21)15-22-23(16-19-7-3-1-4-8-19)17-20-9-5-2-6-10-20/h1-15,24H,16-17H2/b22-15+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103126 (CHEMBL68011 | N,N-Dibenzyl-N'-[1-pyridin-3-yl-meth...) Show SMILES C(N(Cc1ccccc1)\N=C\c1cccnc1)c1ccccc1 Show InChI InChI=1S/C20H19N3/c1-3-8-18(9-4-1)16-23(17-19-10-5-2-6-11-19)22-15-20-12-7-13-21-14-20/h1-15H,16-17H2/b22-15+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus)	BDBM50529620 (CHEMBL4558600) Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@](C)(O)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)C[C@@H](OC(C)=O)[C@H](OC(=O)\C=C\c1ccc(O)c(OC)c1)C2(C)C |r,t:9| Show InChI InChI=1S/C42H58O9/c1-24-16-19-42(36(46)47)21-20-39(6)27(34(42)41(24,8)48)12-14-32-38(5)23-30(50-25(2)43)35(37(3,4)31(38)17-18-40(32,39)7)51-33(45)15-11-26-10-13-28(44)29(22-26)49-9/h10-13,15,22,24,30-32,34-35,44,48H,14,16-21,23H2,1-9H3,(H,46,47)/b15-11+/t24-,30-,31+,32-,34-,35+,38+,39-,40-,41-,42+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Laval Curated by ChEMBL					Assay Description Inhibition of glucose-6-phosphatase in rat H42E cells using glucose-6-phosphate as substrate preincubated overnight followed by substrate addition an...				J Nat Prod 81: 2169-2176 (2018) Article DOI: 10.1021/acs.jnatprod.8b00079 BindingDB Entry DOI: 10.7270/Q2VM4GRR
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus)	BDBM50529620 (CHEMBL4558600) Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@](C)(O)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)C[C@@H](OC(C)=O)[C@H](OC(=O)\C=C\c1ccc(O)c(OC)c1)C2(C)C |r,t:9| Show InChI InChI=1S/C42H58O9/c1-24-16-19-42(36(46)47)21-20-39(6)27(34(42)41(24,8)48)12-14-32-38(5)23-30(50-25(2)43)35(37(3,4)31(38)17-18-40(32,39)7)51-33(45)15-11-26-10-13-28(44)29(22-26)49-9/h10-13,15,22,24,30-32,34-35,44,48H,14,16-21,23H2,1-9H3,(H,46,47)/b15-11+/t24-,30-,31+,32-,34-,35+,38+,39-,40-,41-,42+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Laval Curated by ChEMBL					Assay Description Inhibition of glucose-6-phosphatase in rat H42E cells using glucose-6-phosphate as substrate preincubated overnight followed by substrate addition an...				J Nat Prod 81: 2169-2176 (2018) Article DOI: 10.1021/acs.jnatprod.8b00079 BindingDB Entry DOI: 10.7270/Q2VM4GRR
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103120 (CHEMBL69497 | N,N-Dibenzyl-N'-[1-pyridin-2-yl-meth...) Show SMILES C(N(Cc1ccccc1)\N=C\c1ccccn1)c1ccccc1 Show InChI InChI=1S/C20H19N3/c1-3-9-18(10-4-1)16-23(17-19-11-5-2-6-12-19)22-15-20-13-7-8-14-21-20/h1-15H,16-17H2/b22-15+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus)	BDBM50389999 (CHEMBL2071306) Show SMILES O[C@@H]1[C@@H](COC(=O)\C=C\c2ccc(O)c(O)c2)O[C@@H](O[C@@H]2COC(=O)C2)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C19H22O11/c20-11-3-1-9(5-12(11)21)2-4-14(22)28-8-13-16(24)17(25)18(26)19(30-13)29-10-6-15(23)27-7-10/h1-5,10,13,16-21,24-26H,6-8H2/b4-2+/t10-,13+,16+,17-,18+,19+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ottawa Curated by ChEMBL					Assay Description Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assay				J Nat Prod 75: 1284-8 (2012) Article DOI: 10.1021/np3001317 BindingDB Entry DOI: 10.7270/Q2VM4DBJ
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103124 (CHEMBL67272 | [5-(Dibenzyl-hydrazonomethyl)-furan-...) Show SMILES OCc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)o1 Show InChI InChI=1S/C20H20N2O2/c23-16-20-12-11-19(24-20)13-21-22(14-17-7-3-1-4-8-17)15-18-9-5-2-6-10-18/h1-13,23H,14-16H2/b21-13+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103112 (CHEMBL71650 | N,N-Dibenzyl-N'-[1-pyridin-4-yl-meth...) Show SMILES C(N(Cc1ccccc1)\N=C\c1ccncc1)c1ccccc1 Show InChI InChI=1S/C20H19N3/c1-3-7-19(8-4-1)16-23(17-20-9-5-2-6-10-20)22-15-18-11-13-21-14-12-18/h1-15H,16-17H2/b22-15+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103121 (CHEMBL419070 | N,N-Dibenzyl-N'-[1-phenyl-eth-(E)-y...) Show SMILES CC(=NN(Cc1ccccc1)Cc1ccccc1)c1ccccc1 |w:2.2| Show InChI InChI=1S/C22H22N2/c1-19(22-15-9-4-10-16-22)23-24(17-20-11-5-2-6-12-20)18-21-13-7-3-8-14-21/h2-16H,17-18H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103109 (CHEMBL66774 | N,N-Dibenzyl-N'-[3,4-dihydro-2H-naph...) Show SMILES C(N(Cc1ccccc1)N=C1CCCc2ccccc12)c1ccccc1 |w:9.9| Show InChI InChI=1S/C24H24N2/c1-3-10-20(11-4-1)18-26(19-21-12-5-2-6-13-21)25-24-17-9-15-22-14-7-8-16-23(22)24/h1-8,10-14,16H,9,15,17-19H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103116 (CHEMBL68981 | N,N-Dibenzyl-N'-[6-methoxy-3,4-dihyd...) Show SMILES COc1ccc2C(CCCc2c1)=NN(Cc1ccccc1)Cc1ccccc1 |w:12.14| Show InChI InChI=1S/C25H26N2O/c1-28-23-15-16-24-22(17-23)13-8-14-25(24)26-27(18-20-9-4-2-5-10-20)19-21-11-6-3-7-12-21/h2-7,9-12,15-17H,8,13-14,18-19H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50277824 (4'-Amino-4-fluoro-2'',4''-dimethoxy-6'-methylsulfa...) Show SMILES COc1ccc(c(OC)c1)-c1c(C#N)c(N)c(C#N)c(SC)c1-c1ccc(F)cc1 |(18.9,-.54,;20.24,-1.31,;21.57,-.54,;21.57,1.01,;22.9,1.77,;24.24,1,;24.24,-.53,;25.57,-1.3,;25.58,-2.84,;22.91,-1.31,;25.57,1.77,;26.9,1,;26.9,-.54,;26.89,-2.08,;28.24,1.77,;29.58,1,;28.23,3.32,;29.57,4.1,;30.89,4.88,;26.9,4.08,;26.89,5.62,;28.23,6.4,;25.57,3.31,;24.24,4.08,;24.24,5.62,;22.91,6.39,;21.58,5.62,;20.24,6.39,;21.58,4.08,;22.91,3.31,)| Show InChI InChI=1S/C23H18FN3O2S/c1-28-15-8-9-16(19(10-15)29-2)21-17(11-25)22(27)18(12-26)23(30-3)20(21)13-4-6-14(24)7-5-13/h4-10H,27H2,1-3H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of glucose-6-phosphatase (unknown origin)				Bioorg Med Chem Lett 19: 2158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.02.118 BindingDB Entry DOI: 10.7270/Q28G8KKM
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus)	BDBM50294478 ((E)-4-phenyl-1-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-...) Show SMILES OC[C@H]1O[C@@H](CC(=O)C=Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O |r,w:8.7| Show InChI InChI=1S/C16H20O6/c17-9-13-15(20)16(21)14(19)12(22-13)8-11(18)7-6-10-4-2-1-3-5-10/h1-7,12-17,19-21H,8-9H2/t12-,13+,14-,15+,16+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of rat liver glucose-6-phosphatase				Bioorg Med Chem Lett 19: 2699-703 (2009) Article DOI: 10.1016/j.bmcl.2009.03.136 BindingDB Entry DOI: 10.7270/Q20V8CTK
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus)	BDBM50294477 ((E)-1-(beta-D-glucopyranosyl)-4-(4'-chlorophenyl)b...) Show SMILES OC[C@H]1O[C@@H](CC(=O)C=Cc2ccc(Cl)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r,w:8.7| Show InChI InChI=1S/C16H19ClO6/c17-10-4-1-9(2-5-10)3-6-11(19)7-12-14(20)16(22)15(21)13(8-18)23-12/h1-6,12-16,18,20-22H,7-8H2/t12-,13+,14-,15+,16+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of rat liver glucose-6-phosphatase				Bioorg Med Chem Lett 19: 2699-703 (2009) Article DOI: 10.1016/j.bmcl.2009.03.136 BindingDB Entry DOI: 10.7270/Q20V8CTK
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103113 (CHEMBL69758 | [4-(Dibenzyl-hydrazonomethyl)-phenyl...) Show SMILES CN(C)c1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)cc1 Show InChI InChI=1S/C23H25N3/c1-25(2)23-15-13-20(14-16-23)17-24-26(18-21-9-5-3-6-10-21)19-22-11-7-4-8-12-22/h3-17H,18-19H2,1-2H3/b24-17+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103123 (CHEMBL68153 | N,N-Dibenzyl-N'-[2-phenyl-eth-(E)-yl...) Show SMILES C(C=NN(Cc1ccccc1)Cc1ccccc1)c1ccccc1 |w:1.0| Show InChI InChI=1S/C22H22N2/c1-4-10-20(11-5-1)16-17-23-24(18-21-12-6-2-7-13-21)19-22-14-8-3-9-15-22/h1-15,17H,16,18-19H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103117 (CHEMBL302496 | N,N-Dibenzyl-N'-[1-(3,5-dichloro-ph...) Show SMILES Clc1cc(Cl)cc(\C=N\N(Cc2ccccc2)Cc2ccccc2)c1 Show InChI InChI=1S/C21H18Cl2N2/c22-20-11-19(12-21(23)13-20)14-24-25(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14H,15-16H2/b24-14+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103127 (CHEMBL69742 | N,N-Dibenzyl-N'-[1-(5-nitro-furan-2-...) Show SMILES [#8-]-[#7+](=O)-c1ccc(-[#6-]\[#7]=[#7+](/[#6]-c2ccccc2)-[#6]-c2ccccc2)o1 Show InChI InChI=1S/C19H17N3O3/c23-22(24)19-12-11-18(25-19)13-20-21(14-16-7-3-1-4-8-16)15-17-9-5-2-6-10-17/h1-13H,14-15H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50103108 (CHEMBL304503 | N,N-Dibenzyl-N'-[1-(2-methoxy-pheny...) Show SMILES COc1ccccc1\C=N\N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C22H22N2O/c1-25-22-15-9-8-14-21(22)16-23-24(17-19-10-4-2-5-11-19)18-20-12-6-3-7-13-20/h2-16H,17-18H2,1H3/b23-16+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.				Bioorg Med Chem Lett 11: 2165-7 (2001) BindingDB Entry DOI: 10.7270/Q2M61JJF
					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus)	BDBM50390000 (CHEMBL2071309) Show SMILES OC[C@H]1O[C@@H](O[C@@H]2COC(=O)C2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C10H16O8/c11-2-5-7(13)8(14)9(15)10(18-5)17-4-1-6(12)16-3-4/h4-5,7-11,13-15H,1-3H2/t4-,5+,7+,8-,9+,10+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.91E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ottawa Curated by ChEMBL					Assay Description Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assay				J Nat Prod 75: 1284-8 (2012) Article DOI: 10.1021/np3001317 BindingDB Entry DOI: 10.7270/Q2VM4DBJ
					More data for this Ligand-Target Pair