Compile Data Set for Download or QSAR

Found 210 hits Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase-like protein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190690 (US9181233, 67) Show SMILES COc1ccc(SCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc1OC Show InChI InChI=1S/C18H16N4O2S2/c1-23-15-6-4-12(8-16(15)24-2)25-9-17-21-22-18(26-17)11-3-5-13-14(7-11)20-10-19-13/h3-8,10H,9H2,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10	-46.4	80	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM124974 (US8772508, 8) Show SMILES Cc1cncn1CCCCN\C(NC1CCCCC1)=C/[N+]([O-])=O Show InChI InChI=1S/C16H27N5O2/c1-14-11-17-13-20(14)10-6-5-9-18-16(12-21(22)23)19-15-7-3-2-4-8-15/h11,13,15H,2-10,12H2,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	n/a	580	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM50299866 (CHEMBL578153 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...) Show SMILES Cc1cncn1CCCN=C(C[N+]([O-])=O)Nc1ccc(cc1)C(F)(F)F |w:9.9| Show InChI InChI=1S/C16H18F3N5O2/c1-12-9-20-11-23(12)8-2-7-21-15(10-24(25)26)22-14-5-3-13(4-6-14)16(17,18)19/h3-6,9,11H,2,7-8,10H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	34	n/a	430	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190685 (US9181233, 60) Show SMILES COc1cccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c1 Show InChI InChI=1S/C18H16N4OS/c1-23-14-4-2-3-12(9-14)5-8-17-21-22-18(24-17)13-6-7-15-16(10-13)20-11-19-15/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	40	-42.9	450	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM50299867 (CHEMBL565907 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...) Show SMILES Cc1cncn1CCCN=C(C[N+]([O-])=O)Nc1cccc2ccccc12 |w:9.9| Show InChI InChI=1S/C19H21N5O2/c1-15-12-20-14-23(15)11-5-10-21-19(13-24(25)26)22-18-9-4-7-16-6-2-3-8-17(16)18/h2-4,6-9,12,14H,5,10-11,13H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	41	n/a	230	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190679 (US9181233, 52) Show SMILES COc1ccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc1Cl Show InChI InChI=1S/C18H15ClN4OS/c1-24-16-6-2-11(8-13(16)19)3-7-17-22-23-18(25-17)12-4-5-14-15(9-12)21-10-20-14/h2,4-6,8-10H,3,7H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50	-42.4	680	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM50299865 (CHEMBL567406 | N-(-1-(3-(5-Methyl-1H-imidazol-1-yl...) Show SMILES Cc1cncn1CCCN=C(C[N+]([O-])=O)Nc1ccc(Cl)cc1 |w:9.9| Show InChI InChI=1S/C15H18ClN5O2/c1-12-9-17-11-20(12)8-2-7-18-15(10-21(22)23)19-14-5-3-13(16)4-6-14/h3-6,9,11H,2,7-8,10H2,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	51	n/a	320	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM124971 (US8772508, 2) Show SMILES COc1ccc(N\C(NCCCn2cncc2C)=C\[N+]([O-])=O)c(OC)c1 Show InChI InChI=1S/C17H23N5O4/c1-13-10-18-12-21(13)8-4-7-19-17(11-22(23)24)20-15-6-5-14(25-2)9-16(15)26-3/h5-6,9-10,12H,4,7-8,11H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	55	n/a	530	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190676 (US9181233, 47) Show SMILES COc1ccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc1OC Show InChI InChI=1S/C19H18N4O2S/c1-24-16-7-3-12(9-17(16)25-2)4-8-18-22-23-19(26-18)13-5-6-14-15(10-13)21-11-20-14/h3,5-7,9-11H,4,8H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	60	-41.9	400	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190680 (US9181233, 54) Show SMILES C(Cc1ccc2OCOc2c1)c1nnc(s1)-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C18H14N4O2S/c1-5-15-16(24-10-23-15)7-11(1)2-6-17-21-22-18(25-17)12-3-4-13-14(8-12)20-9-19-13/h1,3-5,7-9H,2,6,10H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	60	-41.9	590	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM124975 (US8772508, 9) Show SMILES Cc1cncn1CCCN\C(Nc1ccc2OCOc2c1)=C/[N+]([O-])=O Show InChI InChI=1S/C16H19N5O4/c1-12-8-17-10-20(12)6-2-5-18-16(9-21(22)23)19-13-3-4-14-15(7-13)25-11-24-14/h3-4,7-8,10H,2,5-6,9,11H2,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	67	n/a	340	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM50299868 (CHEMBL565908 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...) Show SMILES Cc1cncn1CCCN=C(C[N+]([O-])=O)Nc1ccc2OCCOc2c1 |w:9.9| Show InChI InChI=1S/C17H21N5O4/c1-13-10-18-12-21(13)6-2-5-19-17(11-22(23)24)20-14-3-4-15-16(9-14)26-8-7-25-15/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	67	n/a	460	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM124973 (US8772508, 4) Show SMILES COc1ccc(N\C(NCCCn2cncc2C)=C\[N+]([O-])=O)cc1OC Show InChI InChI=1S/C17H23N5O4/c1-13-10-18-12-21(13)8-4-7-19-17(11-22(23)24)20-14-5-6-15(25-2)16(9-14)26-3/h5-6,9-10,12H,4,7-8,11H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	76	n/a	730	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190695 (US9181233, 86) Show SMILES COc1ccc(CCn2cc(nn2)-c2ccc3[nH]cnc3c2)cc1 Show InChI InChI=1S/C18H17N5O/c1-24-15-5-2-13(3-6-15)8-9-23-11-18(21-22-23)14-4-7-16-17(10-14)20-12-19-16/h2-7,10-12H,8-9H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	-41.2	290	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM50299864 (CHEMBL574357 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...) Show SMILES Cc1cncn1CCCN=C(C[N+]([O-])=O)NC1CCCCC1 |w:9.9| Show InChI InChI=1S/C15H25N5O2/c1-13-10-16-12-19(13)9-5-8-17-15(11-20(21)22)18-14-6-3-2-4-7-14/h10,12,14H,2-9,11H2,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	80	n/a	340	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190687 (US9181233, 62) Show SMILES COc1ccc(OC)c(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c1 Show InChI InChI=1S/C19H18N4O2S/c1-24-14-5-7-17(25-2)12(9-14)4-8-18-22-23-19(26-18)13-3-6-15-16(10-13)21-11-20-15/h3,5-7,9-11H,4,8H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	-41.2	480	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190671 (US9181233, 10) Show SMILES C(c1ccc(Oc2ccccc2)cc1)n1cnnc1-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C22H17N5O/c1-2-4-18(5-3-1)28-19-9-6-16(7-10-19)13-27-15-25-26-22(27)17-8-11-20-21(12-17)24-14-23-20/h1-12,14-15H,13H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	-41.2	480	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190681 (US9181233, 55) Show SMILES COc1cc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc(OC)c1OC Show InChI InChI=1S/C20H20N4O3S/c1-25-16-8-12(9-17(26-2)19(16)27-3)4-7-18-23-24-20(28-18)13-5-6-14-15(10-13)22-11-21-14/h5-6,8-11H,4,7H2,1-3H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	-41.2	490	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190678 (US9181233, 50) Show SMILES CSc1ccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc1 Show InChI InChI=1S/C18H16N4S2/c1-23-14-6-2-12(3-7-14)4-9-17-21-22-18(24-17)13-5-8-15-16(10-13)20-11-19-15/h2-3,5-8,10-11H,4,9H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	-41.2	760	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190677 (US9181233, 49) Show SMILES COc1cccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c1OC Show InChI InChI=1S/C19H18N4O2S/c1-24-16-5-3-4-12(18(16)25-2)7-9-17-22-23-19(26-17)13-6-8-14-15(10-13)21-11-20-14/h3-6,8,10-11H,7,9H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	90	-40.9	360	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM124972 (US8772508, 3) Show SMILES COc1cc(N\C(NCCCn2cncc2C)=C\[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C18H25N5O5/c1-13-10-19-12-22(13)7-5-6-20-17(11-23(24)25)21-14-8-15(26-2)18(28-4)16(9-14)27-3/h8-10,12H,5-7,11H2,1-4H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	96	n/a	620	n/a	n/a	n/a	n/a	8.0	n/a
Probiodrug AG US Patent					Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...				US Patent US8772508 (2014) BindingDB Entry DOI: 10.7270/Q2R78CW3
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190688 (US9181233, 63) Show SMILES COc1cccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c1Cl Show InChI InChI=1S/C18H15ClN4OS/c1-24-15-4-2-3-11(17(15)19)6-8-16-22-23-18(25-16)12-5-7-13-14(9-12)21-10-20-13/h2-5,7,9-10H,6,8H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	100	-40.6	220	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190694 (US9181233, 85) Show SMILES COc1ccc(CCn2cc(nn2)-c2ccc3[nH]cnc3c2)cc1OC Show InChI InChI=1S/C19H19N5O2/c1-25-18-6-3-13(9-19(18)26-2)7-8-24-11-17(22-23-24)14-4-5-15-16(10-14)21-12-20-15/h3-6,9-12H,7-8H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	100	-40.6	470	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190669 (US9181233, 8) Show SMILES COc1ccc(Cn2cnnc2-c2ccc3[nH]cnc3c2)cc1 Show InChI InChI=1S/C17H15N5O/c1-23-14-5-2-12(3-6-14)9-22-11-20-21-17(22)13-4-7-15-16(8-13)19-10-18-15/h2-8,10-11H,9H2,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	110	-40.4	640	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190672 (US9181233, 22) Show SMILES Clc1cccc(Cn2cnnc2-c2ccc3[nH]cnc3c2)c1Cl Show InChI InChI=1S/C16H11Cl2N5/c17-12-3-1-2-11(15(12)18)7-23-9-21-22-16(23)10-4-5-13-14(6-10)20-8-19-13/h1-6,8-9H,7H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	120	-40.2	520	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190689 (US9181233, 65) Show SMILES C(Sc1ccccc1)c1nnc(s1)-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C16H12N4S2/c1-2-4-12(5-3-1)21-9-15-19-20-16(22-15)11-6-7-13-14(8-11)18-10-17-13/h1-8,10H,9H2,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	120	-40.2	530	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190696 (US9181233, 87) Show SMILES COc1cccc(CCn2cc(nn2)-c2ccc3[nH]cnc3c2)c1 Show InChI InChI=1S/C18H17N5O/c1-24-15-4-2-3-13(9-15)7-8-23-11-18(21-22-23)14-5-6-16-17(10-14)20-12-19-16/h2-6,9-12H,7-8H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	120	-40.2	550	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190684 (US9181233, 59) Show SMILES Fc1cccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c1 Show InChI InChI=1S/C17H13FN4S/c18-13-3-1-2-11(8-13)4-7-16-21-22-17(23-16)12-5-6-14-15(9-12)20-10-19-14/h1-3,5-6,8-10H,4,7H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	120	-40.2	560	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190693 (US9181233, 84) Show SMILES C(Sc1ccccc1)n1cc(nn1)-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C16H13N5S/c1-2-4-13(5-3-1)22-11-21-9-16(19-20-21)12-6-7-14-15(8-12)18-10-17-14/h1-10H,11H2,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	120	-40.2	570	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190674 (US9181233, 39) Show SMILES COc1ccc(CCc2nnc(o2)-c2ccc3[nH]cnc3c2)cc1Cl Show InChI InChI=1S/C18H15ClN4O2/c1-24-16-6-2-11(8-13(16)19)3-7-17-22-23-18(25-17)12-4-5-14-15(9-12)21-10-20-14/h2,4-6,8-10H,3,7H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	130	-40.0	800	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190682 (US9181233, 57) Show SMILES Fc1ccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c(F)c1 Show InChI InChI=1S/C17H12F2N4S/c18-12-4-1-10(13(19)8-12)3-6-16-22-23-17(24-16)11-2-5-14-15(7-11)21-9-20-14/h1-2,4-5,7-9H,3,6H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	130	-40.0	830	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190692 (US9181233, 83) Show SMILES C(Cn1cc(nn1)-c1ccc2[nH]cnc2c1)c1ccccc1 Show InChI InChI=1S/C17H15N5/c1-2-4-13(5-3-1)8-9-22-11-17(20-21-22)14-6-7-15-16(10-14)19-12-18-15/h1-7,10-12H,8-9H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	140	-39.8	570	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190683 (US9181233, 58) Show SMILES Fc1ccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc1F Show InChI InChI=1S/C17H12F2N4S/c18-12-4-1-10(7-13(12)19)2-6-16-22-23-17(24-16)11-3-5-14-15(8-11)21-9-20-14/h1,3-5,7-9H,2,6H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	140	-39.8	720	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190691 (US9181233, 68) Show SMILES COc1ccc(cc1OC)S(=O)(=O)Cc1nnc(s1)-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C18H16N4O4S2/c1-25-15-6-4-12(8-16(15)26-2)28(23,24)9-17-21-22-18(27-17)11-3-5-13-14(7-11)20-10-19-13/h3-8,10H,9H2,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	150	-39.6	410	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190686 (US9181233, 61) Show SMILES COc1ccccc1CCc1nnc(s1)-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C18H16N4OS/c1-23-16-5-3-2-4-12(16)7-9-17-21-22-18(24-17)13-6-8-14-15(10-13)20-11-19-14/h2-6,8,10-11H,7,9H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	170	-39.3	760	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190675 (US9181233, 46) Show SMILES C(Cc1ccccc1)c1nnc(s1)-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C17H14N4S/c1-2-4-12(5-3-1)6-9-16-20-21-17(22-16)13-7-8-14-15(10-13)19-11-18-14/h1-5,7-8,10-11H,6,9H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	180	-39.1	640	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190670 (US9181233, 9) Show SMILES Clc1ccccc1Cn1cnnc1-c1ccc2[nH]cnc2c1 Show InChI InChI=1S/C16H12ClN5/c17-13-4-2-1-3-12(13)8-22-10-20-21-16(22)11-5-6-14-15(7-11)19-9-18-14/h1-7,9-10H,8H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	200	-38.9	760	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM190673 (US9181233, 24) Show SMILES COc1ccc(Cn2cnnc2-c2ccc3[nH]cnc3c2)cc1Cl Show InChI InChI=1S/C17H14ClN5O/c1-24-16-5-2-11(6-13(16)18)8-23-10-21-22-17(23)12-3-4-14-15(7-12)20-9-19-14/h2-7,9-10H,8H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	230	-38.5	850	n/a	n/a	n/a	n/a	n/a	30
PROBIODRUG AG US Patent					Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...				US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 15 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 16 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 21 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 26 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 8 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 4 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 32 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	US20240059675, Example 13 Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM637843 (US11834440, Compound 44B) Show SMILES FC(F)CCOc1cc(F)c([C@H]2[C@@H](C3COC3)C(=O)N2c2ccc3[nH]cnc3c2)c(F)c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM637845 (US11834440, Compound 45B) Show SMILES FC(F)CCOc1ccc(cn1)[C@H]1[C@@H](C2CC2)C(=O)N1c1ccc2[nH]cnc2c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM637847 (US11834440, Compound 46B) Show SMILES FC(F)(F)n1cc(cn1)-c1ccc(nc1)[C@H]1[C@@H](C2CC2)C(=O)N1c1ccc2[nH]cnc2c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human))	BDBM637848 (US11834440, Compound 47B) Show SMILES Fc1cc(cc(F)c1[C@H]1[C@@H](C2CC2)C(=O)N1c1ccc2[nH]cnc2c1)-c1ccn(n1)C(F)(F)F |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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