Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'p53 binding protein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p53 binding protein (Homo sapiens (Human))	BDBM81636 (BZD Scaffold, 6) Show SMILES [O-]C(=O)C(N1C(c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H15Cl2IN2O4/c24-14-5-1-12(2-6-14)19-21(29)27-18-10-9-16(26)11-17(18)22(30)28(19)20(23(31)32)13-3-7-15(25)8-4-13/h1-11,19-20H,(H,27,29)(H,31,32)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development					Assay Description Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.				Chem Biol Drug Des 67: 201-5 (2006) Article DOI: 10.1111/j.1747-0285.2006.00365.x BindingDB Entry DOI: 10.7270/Q2BP018M
					More data for this Ligand-Target Pair
p53 binding protein (Homo sapiens (Human))	BDBM81632 (BZD Scaffold, 2) Show SMILES CC(C)c1ccc2NC(=O)C(N(C(C([O-])=O)c3ccc(Cl)cc3)C(=O)c2c1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22Cl2N2O4/c1-14(2)17-7-12-21-20(13-17)25(32)30(23(26(33)34)16-5-10-19(28)11-6-16)22(24(31)29-21)15-3-8-18(27)9-4-15/h3-14,22-23H,1-2H3,(H,29,31)(H,33,34)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development					Assay Description Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.				Chem Biol Drug Des 67: 201-5 (2006) Article DOI: 10.1111/j.1747-0285.2006.00365.x BindingDB Entry DOI: 10.7270/Q2BP018M
					More data for this Ligand-Target Pair
p53 binding protein (Homo sapiens (Human))	BDBM81635 (BZD Scaffold, 5) Show SMILES [O-]C(=O)C(N1C(c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1 Show InChI InChI=1S/C23H16ClIN2O4/c24-15-8-6-14(7-9-15)19-21(28)26-18-11-10-16(25)12-17(18)22(29)27(19)20(23(30)31)13-4-2-1-3-5-13/h1-12,19-20H,(H,26,28)(H,30,31)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development					Assay Description Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.				Chem Biol Drug Des 67: 201-5 (2006) Article DOI: 10.1111/j.1747-0285.2006.00365.x BindingDB Entry DOI: 10.7270/Q2BP018M
					More data for this Ligand-Target Pair
p53 binding protein (Homo sapiens (Human))	BDBM81634 (BZD Scaffold, 4) Show SMILES [O-]C(=O)C(N1C(c2ccc(cc2)C(F)(F)F)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1 Show InChI InChI=1S/C24H16F3IN2O4/c25-24(26,27)15-8-6-14(7-9-15)19-21(31)29-18-11-10-16(28)12-17(18)22(32)30(19)20(23(33)34)13-4-2-1-3-5-13/h1-12,19-20H,(H,29,31)(H,33,34)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development					Assay Description Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.				Chem Biol Drug Des 67: 201-5 (2006) Article DOI: 10.1111/j.1747-0285.2006.00365.x BindingDB Entry DOI: 10.7270/Q2BP018M
					More data for this Ligand-Target Pair
p53 binding protein (Homo sapiens (Human))	BDBM81633 (BZD Scaffold, 3) Show SMILES [O-]C(=O)C(N1C(c2ccccc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1 Show InChI InChI=1S/C23H17IN2O4/c24-16-11-12-18-17(13-16)22(28)26(20(23(29)30)15-9-5-2-6-10-15)19(21(27)25-18)14-7-3-1-4-8-14/h1-13,19-20H,(H,25,27)(H,29,30)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development					Assay Description Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.				Chem Biol Drug Des 67: 201-5 (2006) Article DOI: 10.1111/j.1747-0285.2006.00365.x BindingDB Entry DOI: 10.7270/Q2BP018M
					More data for this Ligand-Target Pair
p53 binding protein (Homo sapiens (Human))	BDBM81631 (BZD Scaffold, 1) Show SMILES [O-]C(=O)C(N1C(c2ccccc2)C(=O)Nc2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C23H18N2O4/c26-21-19(15-9-3-1-4-10-15)25(20(23(28)29)16-11-5-2-6-12-16)22(27)17-13-7-8-14-18(17)24-21/h1-14,19-20H,(H,24,26)(H,28,29)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development					Assay Description Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.				Chem Biol Drug Des 67: 201-5 (2006) Article DOI: 10.1111/j.1747-0285.2006.00365.x BindingDB Entry DOI: 10.7270/Q2BP018M
					More data for this Ligand-Target Pair