Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM223314 (YPYSCWARHVRIREN | piHA-D1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
The University of Tokyo | Assay Description The release of 2-chloro-4-nitrophenol resulting from the HPA-catalyzed hydrolysis of 2-chloro-4-nitrophenyl a-maltotrioside (CNPG3) was monitored at ... | Cell Chem Biol 24: 381-390 (2017) Article DOI: 10.1016/j.chembiol.2017.02.001 BindingDB Entry DOI: 10.7270/Q27D2T0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM223315 (YPYSCWVRHSDPHKF | piHA-D3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
The University of Tokyo | Assay Description The release of 2-chloro-4-nitrophenol resulting from the HPA-catalyzed hydrolysis of 2-chloro-4-nitrophenyl a-maltotrioside (CNPG3) was monitored at ... | Cell Chem Biol 24: 381-390 (2017) Article DOI: 10.1016/j.chembiol.2017.02.001 BindingDB Entry DOI: 10.7270/Q27D2T0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM223316 (YPYSCWVRH | piHA-Dm) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
The University of Tokyo | Assay Description The release of 2-chloro-4-nitrophenol resulting from the HPA-catalyzed hydrolysis of 2-chloro-4-nitrophenyl a-maltotrioside (CNPG3) was monitored at ... | Cell Chem Biol 24: 381-390 (2017) Article DOI: 10.1016/j.chembiol.2017.02.001 BindingDB Entry DOI: 10.7270/Q27D2T0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120854 (CHEMBL3618493) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Competitive inhibition of human pancreatic alpha-amylase by double reciprocal plot analysis | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163646 (Montbretin A (MbA)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.10 | -47.0 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163647 (MbA-G (1)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 9.10 | -46.7 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120850 (CHEMBL3618491) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120851 (CHEMBL1233515) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120843 (CHEMBL3616594) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed... | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120842 (CHEMBL3618489) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed... | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163648 (MbA-R (2)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 21.3 | -44.5 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120844 (CHEMBL3616595) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed... | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163649 (MbA-RX (3)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 42.4 | -42.8 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120852 (CHEMBL1230193) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163650 (MbA-GR (4)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 79.3 | -41.2 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163651 (MbA-GRX (5) | mini-MbA) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 93.3 | -40.8 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163652 (MbA-C (6)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 730 | -35.6 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120848 (CHEMBL3618488) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed... | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163653 (MbA-CG (7)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.24E+3 | -32.8 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120855 (CHEMBL3618494) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Competitive inhibition of human pancreatic alpha-amylase by double reciprocal plot analysis | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120856 (CHEMBL3618495) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Competitive inhibition of human pancreatic alpha-amylase by double reciprocal plot analysis | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM50499987 (CHEMBL3742315) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National University of Singapore Curated by ChEMBL | Assay Description Non-competitive inhibition of porcine pancreatic alpha-amylase by Lineweaver-Burk plot analysis | Bioorg Med Chem 23: 7641-9 (2015) Article DOI: 10.1016/j.bmc.2015.11.008 BindingDB Entry DOI: 10.7270/Q2TH8QPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163656 (3-O-(6-(4-(Caffeamidomethyl)-triazolyl)hexyl)querc...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.39E+4 | -28.2 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120839 (CHEMBL1234040) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysis | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM92367 (GPESB15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.36E+4 | -26.6 | 3.58E+4 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Yonsei University | Assay Description To test whether GCTs share a common binding pocket on PPA with acarbose, we performed an experiment according to the method of Yonetani and Theorell. | Chembiochem 13: 1584-93 (2012) Article DOI: 10.1002/cbic.201200272 BindingDB Entry DOI: 10.7270/Q2ST7NFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50451094 (Ascorbyl Palmitate | Ascorbyl palmitate (E5) | E30...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | PubMed | <4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Canterbury Curated by ChEMBL | Assay Description Inhibitory constant against Alpha-amylase | Bioorg Med Chem Lett 10: 1575-6 (2000) BindingDB Entry DOI: 10.7270/Q2R49R9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50090254 ((R)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,4-di...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | <4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Canterbury Curated by ChEMBL | Assay Description Inhibitory constant against Alpha-amylase | Bioorg Med Chem Lett 10: 1575-6 (2000) BindingDB Entry DOI: 10.7270/Q2R49R9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50351096 (ASCORBIC ACID) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | PubMed | 4.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Canterbury Curated by ChEMBL | Assay Description Inhibitory constant against Alpha-amylase | Bioorg Med Chem Lett 10: 1575-6 (2000) BindingDB Entry DOI: 10.7270/Q2R49R9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163654 (MbA-CR (8)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.68E+4 | -25.1 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM29143 (CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic alpha-amylase using soluble starch as substrate after 30 mins by Bernfeld method | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM163655 (MbA-CGR (9)) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.28E+5 | -22.6 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of British Columbia | Assay Description Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor... | Nat Chem Biol 11: 691-6 (2015) Article DOI: 10.1038/nchembio.1865 BindingDB Entry DOI: 10.7270/Q2KD1WP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM92366 (GPESB14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.04E+5 | -21.9 | 8.89E+4 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Yonsei University | Assay Description To test whether GCTs share a common binding pocket on PPA with acarbose, we performed an experiment according to the method of Yonetani and Theorell. | Chembiochem 13: 1584-93 (2012) Article DOI: 10.1002/cbic.201200272 BindingDB Entry DOI: 10.7270/Q2ST7NFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM92365 (GPESB11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.34E+5 | -21.6 | 1.25E+5 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Yonsei University | Assay Description To test whether GCTs share a common binding pocket on PPA with acarbose, we performed an experiment according to the method of Yonetani and Theorell. | Chembiochem 13: 1584-93 (2012) Article DOI: 10.1002/cbic.201200272 BindingDB Entry DOI: 10.7270/Q2ST7NFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM92363 (GPESB02) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.42E+5 | -20.6 | 1.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Yonsei University | Assay Description To test whether GCTs share a common binding pocket on PPA with acarbose, we performed an experiment according to the method of Yonetani and Theorell. | Chembiochem 13: 1584-93 (2012) Article DOI: 10.1002/cbic.201200272 BindingDB Entry DOI: 10.7270/Q2ST7NFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM92362 (GPESB01) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7.80E+5 | -18.5 | 3.61E+5 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Yonsei University | Assay Description To test whether GCTs share a common binding pocket on PPA with acarbose, we performed an experiment according to the method of Yonetani and Theorell. | Chembiochem 13: 1584-93 (2012) Article DOI: 10.1002/cbic.201200272 BindingDB Entry DOI: 10.7270/Q2ST7NFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM92364 (GPESB07) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.01E+6 | -17.8 | 3.56E+5 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Yonsei University | Assay Description To test whether GCTs share a common binding pocket on PPA with acarbose, we performed an experiment according to the method of Yonetani and Theorell. | Chembiochem 13: 1584-93 (2012) Article DOI: 10.1002/cbic.201200272 BindingDB Entry DOI: 10.7270/Q2ST7NFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120838 (CHEMBL1233953) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.80E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysis | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM50120841 (CHEMBL3616593) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | <1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic alpha-amylase using DP17 amylose as substrate preincubated for 5 mins followed by substrate addition by copper-bicin... | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50120840 (CHEMBL1213470) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysis | Bioorg Med Chem 23: 6725-32 (2015) Article DOI: 10.1016/j.bmc.2015.09.007 BindingDB Entry DOI: 10.7270/Q21G0P2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50033631 (2-{2-[2-(2-{2-[2-tert-Butoxycarbonylamino-3-(4-sul...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
EP CNRS 51 Curated by ChEMBL | Assay Description Tested in vitro for inhibition of amylase release from rat pancreatic acini | J Med Chem 36: 3021-8 (1993) BindingDB Entry DOI: 10.7270/Q2PZ57VG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50033632 (3-{2-[2-(2-{2-[2-tert-Butoxycarbonylamino-3-(4-sul...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
EP CNRS 51 Curated by ChEMBL | Assay Description Tested in vitro for inhibition of amylase release from rat pancreatic acini | J Med Chem 36: 3021-8 (1993) BindingDB Entry DOI: 10.7270/Q2PZ57VG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50033636 (3-{2-[2-(2-{2-[2-tert-Butoxycarbonylamino-3-(4-sul...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
EP CNRS 51 Curated by ChEMBL | Assay Description Tested in vitro for inhibition of amylase release from rat pancreatic acini | J Med Chem 36: 3021-8 (1993) BindingDB Entry DOI: 10.7270/Q2PZ57VG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Homo sapiens (Human)) | BDBM50033636 (3-{2-[2-(2-{2-[2-tert-Butoxycarbonylamino-3-(4-sul...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
EP CNRS 51 Curated by ChEMBL | Assay Description Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from jurkat Tcells | J Med Chem 36: 3021-8 (1993) BindingDB Entry DOI: 10.7270/Q2PZ57VG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Sus scrofa (Pig)) | BDBM223316 (YPYSCWVRH | piHA-Dm) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
The University of Tokyo | Assay Description After kinetic analysis with HPA, piHA-Dm was tested as an inhibitor of ten additional enzymes. The conditions are listed as follows: Agrobacterium fa... | Cell Chem Biol 24: 381-390 (2017) Article DOI: 10.1016/j.chembiol.2017.02.001 BindingDB Entry DOI: 10.7270/Q27D2T0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005681 (2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005684 (2-Cyclohexyl-2-phenyl-propionic acid 3-diethylamin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005685 (2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005686 (2-Cyclohexyl-2-phenyl-propionic acid 2-diethylamin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005682 (2-Cyclohexyl-2-phenyl-propionic acid 4-dimethylami...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic alpha-amylase (Rattus norvegicus) | BDBM50005683 (2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells. | J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0 | |||||||||||
More data for this Ligand-Target Pair |
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