Compile Data Set for Download or QSAR

Found 752 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4-kinase beta'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200009 (CHEMBL3923414) Show SMILES COc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C22H27ClN6O5S/c1-14-21(29-22(26-14)17(13-20(23)27-29)25-7-6-24-15(2)30)16-4-5-18(33-3)19(12-16)35(31,32)28-8-10-34-11-9-28/h4-5,12-13,25H,6-11H2,1-3H3,(H,24,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457851 (CHEMBL4205416) Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2cccnc2)cc1 Show InChI InChI=1S/C22H22N8O2S/c1-32-16-6-4-15(5-7-16)25-22(31)30-11-9-29(10-12-30)18-17-20(28-21(23)27-18)33-19(26-17)14-3-2-8-24-13-14/h2-8,13H,9-12H2,1H3,(H,25,31)(H2,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200098 (CHEMBL3930509) Show SMILES COc1ccc(cc1S(=O)(=O)N(C)C)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C20H25ClN6O4S/c1-12-19(14-6-7-16(31-5)17(10-14)32(29,30)26(3)4)27-20(24-12)15(11-18(21)25-27)23-9-8-22-13(2)28/h6-7,10-11,23H,8-9H2,1-5H3,(H,22,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457886 (CHEMBL4211696) Show SMILES CNC(=O)c1cc(ccc1Cl)-c1ccnc(c1)C(=O)NCc1cccc(c1)-n1cccn1 Show InChI InChI=1S/C24H20ClN5O2/c1-26-23(31)20-13-17(6-7-21(20)25)18-8-10-27-22(14-18)24(32)28-15-16-4-2-5-19(12-16)30-11-3-9-29-30/h2-14H,15H2,1H3,(H,26,31)(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457851 (CHEMBL4205416) Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2cccnc2)cc1 Show InChI InChI=1S/C22H22N8O2S/c1-32-16-6-4-15(5-7-16)25-22(31)30-11-9-29(10-12-30)18-17-20(28-21(23)27-18)33-19(26-17)14-3-2-8-24-13-14/h2-8,13H,9-12H2,1H3,(H,25,31)(H2,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457853 (CHEMBL4215340) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3scnc23)c(C)c1 |r| Show InChI InChI=1S/C19H23N7O2S/c1-11-8-13(28-3)4-5-14(11)22-19(27)25-6-7-26(12(2)9-25)16-15-17(29-10-21-15)24-18(20)23-16/h4-5,8,10,12H,6-7,9H2,1-3H3,(H,22,27)(H2,20,23,24)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457854 (CHEMBL4206816) Show SMILES Cc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2cccnc2)cc1 Show InChI InChI=1S/C22H22N8OS/c1-14-4-6-16(7-5-14)25-22(31)30-11-9-29(10-12-30)18-17-20(28-21(23)27-18)32-19(26-17)15-3-2-8-24-13-15/h2-8,13H,9-12H2,1H3,(H,25,31)(H2,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457855 (CHEMBL4211181) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)ncc23)c(C)c1 |r| Show InChI InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-16(12)23-20(29)27-7-8-28(13(2)11-27)18-15-10-22-26(3)17(15)24-19(21)25-18/h5-6,9-10,13H,7-8,11H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200012 (CHEMBL3958915) Show SMILES CCC(CO)NS(=O)(=O)c1cc(ccc1OC)-c1c(C)nc2c(NCc3ccnc(CC)c3)cc(Cl)nn12 Show InChI InChI=1S/C26H31ClN6O4S/c1-5-19-11-17(9-10-28-19)14-29-21-13-24(27)31-33-25(16(3)30-26(21)33)18-7-8-22(37-4)23(12-18)38(35,36)32-20(6-2)15-34/h7-13,20,29,32,34H,5-6,14-15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50492527 (CHEMBL2407818) Show SMILES Cc1nc2c(NCc3cccc(c3)S(C)(=O)=O)nccn2c1-c1ccc(O)c(F)c1 Show InChI InChI=1S/C21H19FN4O3S/c1-13-19(15-6-7-18(27)17(22)11-15)26-9-8-23-20(21(26)25-13)24-12-14-4-3-5-16(10-14)30(2,28)29/h3-11,27H,12H2,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
BioFocus Curated by ChEMBL					Assay Description Inhibition of recombinant PI4K3beta (unknown origin) using PI:PS as substrate after 75 to 90 mins by scintillation counting analysis in presence of [...				ACS Med Chem Lett 4: 585-9 (2013) Article DOI: 10.1021/ml400095m BindingDB Entry DOI: 10.7270/Q2N58Q8J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50492527 (CHEMBL2407818) Show SMILES Cc1nc2c(NCc3cccc(c3)S(C)(=O)=O)nccn2c1-c1ccc(O)c(F)c1 Show InChI InChI=1S/C21H19FN4O3S/c1-13-19(15-6-7-18(27)17(22)11-15)26-9-8-23-20(21(26)25-13)24-12-14-4-3-5-16(10-14)30(2,28)29/h3-11,27H,12H2,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01467 BindingDB Entry DOI: 10.7270/Q24Q801K
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199888 (CHEMBL3976651) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCCO)ccn1 Show InChI InChI=1S/C24H27ClN6O4S/c1-4-18-11-16(7-8-26-18)14-27-19-13-22(25)30-31-23(15(2)29-24(19)31)17-5-6-20(35-3)21(12-17)36(33,34)28-9-10-32/h5-8,11-13,27-28,32H,4,9-10,14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50595930 (CHEMBL5188324) Show SMILES CCNS(=O)(=O)c1cc(ccc1OO)-c1c(C)nc2c(NCc3ccnc(CC)c3)cc(Cl)nn12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01467 BindingDB Entry DOI: 10.7270/Q24Q801K
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199891 (CHEMBL3920652) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)N2CCC(O)CC2)ccn1 Show InChI InChI=1S/C27H31ClN6O4S/c1-4-20-13-18(7-10-29-20)16-30-22-15-25(28)32-34-26(17(2)31-27(22)34)19-5-6-23(38-3)24(14-19)39(36,37)33-11-8-21(35)9-12-33/h5-7,10,13-15,21,30,35H,4,8-9,11-12,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457848 (CHEMBL4215244) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3sccc23)c(C)c1 |r| Show InChI InChI=1S/C20H24N6O2S/c1-12-10-14(28-3)4-5-16(12)22-20(27)25-7-8-26(13(2)11-25)17-15-6-9-29-18(15)24-19(21)23-17/h4-6,9-10,13H,7-8,11H2,1-3H3,(H,22,27)(H2,21,23,24)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457867 (CHEMBL4203566) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3sncc23)c(C)c1 |r| Show InChI InChI=1S/C19H23N7O2S/c1-11-8-13(28-3)4-5-15(11)22-19(27)25-6-7-26(12(2)10-25)16-14-9-21-29-17(14)24-18(20)23-16/h4-5,8-9,12H,6-7,10H2,1-3H3,(H,22,27)(H2,20,23,24)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200000 (CHEMBL3911522) Show SMILES CCC(CO)NS(=O)(=O)c1cc(ccc1OC)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C22H29ClN6O5S/c1-5-16(12-30)28-35(32,33)19-10-15(6-7-18(19)34-4)21-13(2)26-22-17(11-20(23)27-29(21)22)25-9-8-24-14(3)31/h6-7,10-11,16,25,28,30H,5,8-9,12H2,1-4H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457850 (CHEMBL4203041) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3scnc23)cc1 |r| Show InChI InChI=1S/C18H21N7O2S/c1-11-9-24(18(26)21-12-3-5-13(27-2)6-4-12)7-8-25(11)15-14-16(28-10-20-14)23-17(19)22-15/h3-6,10-11H,7-9H2,1-2H3,(H,21,26)(H2,19,22,23)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50005005 (CHEMBL2397317) Show SMILES COc1ccc(cc1OC)-c1c(C)nn2c(NCCN3CCOCC3)cc(C)nc12 Show InChI InChI=1S/C22H29N5O3/c1-15-13-20(23-7-8-26-9-11-30-12-10-26)27-22(24-15)21(16(2)25-27)17-5-6-18(28-3)19(14-17)29-4/h5-6,13-14,23H,7-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457876 (CHEMBL4209793) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)cnc23)c(C)c1 |r| Show InChI InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-15(12)23-20(29)27-7-8-28(13(2)10-27)18-16-17(24-19(21)25-18)26(3)11-22-16/h5-6,9,11,13H,7-8,10H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457868 (CHEMBL4202450) Show SMILES Cc1nn2c(NCc3ccnc(C)c3)cc(C)nc2c1-c1ccc(Cl)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C22H23ClN6O2S/c1-13-9-16(7-8-24-13)12-25-20-10-14(2)26-22-21(15(3)27-29(20)22)17-5-6-18(23)19(11-17)28-32(4,30)31/h5-11,25,28H,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457853 (CHEMBL4215340) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3scnc23)c(C)c1 |r| Show InChI InChI=1S/C19H23N7O2S/c1-11-8-13(28-3)4-5-14(11)22-19(27)25-6-7-26(12(2)9-25)16-15-17(29-10-21-15)24-18(20)23-16/h4-5,8,10,12H,6-7,9H2,1-3H3,(H,22,27)(H2,20,23,24)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200097 (CHEMBL3939697) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCC=C)ccn1 Show InChI InChI=1S/C25H27ClN6O3S/c1-5-10-29-36(33,34)22-13-18(7-8-21(22)35-4)24-16(3)30-25-20(14-23(26)31-32(24)25)28-15-17-9-11-27-19(6-2)12-17/h5,7-9,11-14,28-29H,1,6,10,15H2,2-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199889 (CHEMBL3957128) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCCN(C)C)ccn1 Show InChI InChI=1S/C26H32ClN7O3S/c1-6-20-13-18(9-10-28-20)16-29-21-15-24(27)32-34-25(17(2)31-26(21)34)19-7-8-22(37-5)23(14-19)38(35,36)30-11-12-33(3)4/h7-10,13-15,29-30H,6,11-12,16H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457860 (CHEMBL4207851) Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3scnc23)c(C)c1 Show InChI InChI=1S/C18H21N7O2S/c1-11-9-12(27-2)3-4-13(11)21-18(26)25-7-5-24(6-8-25)15-14-16(28-10-20-14)23-17(19)22-15/h3-4,9-10H,5-8H2,1-2H3,(H,21,26)(H2,19,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description GRAC: human Y1 selective antagonist				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457870 (CHEMBL1652677) Show SMILES Nc1nc(N2CCN(CC2)C(=O)COc2ccc(Cl)cc2)c2nc(sc2n1)-c1cccnc1 Show InChI InChI=1S/C22H20ClN7O2S/c23-15-3-5-16(6-4-15)32-13-17(31)29-8-10-30(11-9-29)19-18-21(28-22(24)27-19)33-20(26-18)14-2-1-7-25-12-14/h1-7,12H,8-11,13H2,(H2,24,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457855 (CHEMBL4211181) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)ncc23)c(C)c1 |r| Show InChI InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-16(12)23-20(29)27-7-8-28(13(2)11-27)18-15-10-22-26(3)17(15)24-19(21)25-18/h5-6,9-10,13H,7-8,11H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457871 (CHEMBL4210308) Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2ccccc2)cc1 Show InChI InChI=1S/C23H23N7O2S/c1-32-17-9-7-16(8-10-17)25-23(31)30-13-11-29(12-14-30)19-18-21(28-22(24)27-19)33-20(26-18)15-5-3-2-4-6-15/h2-10H,11-14H2,1H3,(H,25,31)(H2,24,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200004 (CHEMBL3959713) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2cccc(c2)S(=O)(=O)N(C)C)ccn1 Show InChI InChI=1S/C23H25ClN6O2S/c1-5-18-11-16(9-10-25-18)14-26-20-13-21(24)28-30-22(15(2)27-23(20)30)17-7-6-8-19(12-17)33(31,32)29(3)4/h6-13,26H,5,14H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200109 (CHEMBL3974986) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCC#C)ccn1 Show InChI InChI=1S/C25H25ClN6O3S/c1-5-10-29-36(33,34)22-13-18(7-8-21(22)35-4)24-16(3)30-25-20(14-23(26)31-32(24)25)28-15-17-9-11-27-19(6-2)12-17/h1,7-9,11-14,28-29H,6,10,15H2,2-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of 6xHisGB1 tagged PI4KB (unknown origin) expressed in Escherichia coli BL21 Star				J Med Chem 60: 119-127 (2017) Article DOI: 10.1021/acs.jmedchem.6b01466 BindingDB Entry DOI: 10.7270/Q2474CVJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457848 (CHEMBL4215244) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3sccc23)c(C)c1 |r| Show InChI InChI=1S/C20H24N6O2S/c1-12-10-14(28-3)4-5-16(12)22-20(27)25-7-8-26(13(2)11-25)17-15-6-9-29-18(15)24-19(21)23-17/h4-6,9-10,13H,7-8,11H2,1-3H3,(H,22,27)(H2,21,23,24)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199998 (CHEMBL3902513) Show SMILES COc1ccc(cc1S(=O)(=O)N1CCC(CO)CC1)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C24H31ClN6O5S/c1-15-23(31-24(28-15)19(13-22(25)29-31)27-9-8-26-16(2)33)18-4-5-20(36-3)21(12-18)37(34,35)30-10-6-17(14-32)7-11-30/h4-5,12-13,17,27,32H,6-11,14H2,1-3H3,(H,26,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200101 (CHEMBL3947384) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NC2CCC(N)CC2)ccn1 |(11.1,-17.02,;11.1,-18.55,;9.77,-19.32,;9.77,-20.86,;8.43,-21.63,;8.43,-23.17,;9.77,-23.94,;9.77,-25.48,;8.43,-26.25,;8.43,-27.79,;7.1,-28.56,;9.77,-28.56,;11.1,-27.79,;12.56,-28.27,;13.48,-27.02,;15.02,-27.02,;12.56,-25.77,;11.1,-26.25,;13.04,-29.73,;12.01,-30.88,;12.48,-32.34,;13.99,-32.66,;14.47,-34.12,;13.44,-35.27,;15.03,-31.52,;14.55,-30.05,;16.53,-31.83,;16.92,-30.34,;18.02,-31.43,;17.22,-33.21,;18.76,-33.29,;19.46,-34.66,;21,-34.74,;21.84,-33.45,;23.38,-33.53,;21.14,-32.07,;19.6,-32,;7.1,-20.86,;7.1,-19.32,;8.43,-18.55,)| Show InChI InChI=1S/C28H34ClN7O3S/c1-4-21-13-18(11-12-31-21)16-32-23-15-26(29)34-36-27(17(2)33-28(23)36)19-5-10-24(39-3)25(14-19)40(37,38)35-22-8-6-20(30)7-9-22/h5,10-15,20,22,32,35H,4,6-9,16,30H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457870 (CHEMBL1652677) Show SMILES Nc1nc(N2CCN(CC2)C(=O)COc2ccc(Cl)cc2)c2nc(sc2n1)-c1cccnc1 Show InChI InChI=1S/C22H20ClN7O2S/c23-15-3-5-16(6-4-15)32-13-17(31)29-8-10-30(11-9-29)19-18-21(28-22(24)27-19)33-20(26-18)14-2-1-7-25-12-14/h1-7,12H,8-11,13H2,(H2,24,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200005 (CHEMBL3929556) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCCOC)ccn1 Show InChI InChI=1S/C25H29ClN6O4S/c1-5-19-12-17(8-9-27-19)15-28-20-14-23(26)31-32-24(16(2)30-25(20)32)18-6-7-21(36-4)22(13-18)37(33,34)29-10-11-35-3/h6-9,12-14,28-29H,5,10-11,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457886 (CHEMBL4211696) Show SMILES CNC(=O)c1cc(ccc1Cl)-c1ccnc(c1)C(=O)NCc1cccc(c1)-n1cccn1 Show InChI InChI=1S/C24H20ClN5O2/c1-26-23(31)20-13-17(6-7-21(20)25)18-8-10-27-22(14-18)24(32)28-15-16-4-2-5-19(12-16)30-11-3-9-29-30/h2-14H,15H2,1H3,(H,26,31)(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200105 (CHEMBL3894217) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)N2CCOCC2)ccn1 Show InChI InChI=1S/C26H29ClN6O4S/c1-4-20-13-18(7-8-28-20)16-29-21-15-24(27)31-33-25(17(2)30-26(21)33)19-5-6-22(36-3)23(14-19)38(34,35)32-9-11-37-12-10-32/h5-8,13-15,29H,4,9-12,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50341209 (9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...) Show SMILES Nc1ccc(cn1)-c1ccc2ncc3ccc(=O)n(-c4cccc(c4)C(F)(F)F)c3c2c1 Show InChI InChI=1S/C24H15F3N4O/c25-24(26,27)17-2-1-3-18(11-17)31-22(32)9-6-16-13-29-20-7-4-14(10-19(20)23(16)31)15-5-8-21(28)30-12-15/h1-13H,(H2,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Dana Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of PI4K beta				J Med Chem 54: 1473-80 (2011) Article DOI: 10.1021/jm101520v BindingDB Entry DOI: 10.7270/Q2S46S8H
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457862 (CHEMBL4204100) Show SMILES COc1ccc(NC(=O)N2CCN(C(C)C2)c2nc(N)nc3scnc23)cc1 Show InChI InChI=1S/C18H21N7O2S/c1-11-9-24(18(26)21-12-3-5-13(27-2)6-4-12)7-8-25(11)15-14-16(28-10-20-14)23-17(19)22-15/h3-6,10-11H,7-9H2,1-2H3,(H,21,26)(H2,19,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50042924 (CHEMBL1229535) Show SMILES CC(=O)\N=c1\[nH]c(C)c(s1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO Show InChI InChI=1S/C14H16ClN3O4S2/c1-8-13(23-14(17-8)18-9(2)20)10-3-4-11(15)12(7-10)24(21,22)16-5-6-19/h3-4,7,16,19H,5-6H2,1-2H3,(H,17,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta (unknown origin)				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457854 (CHEMBL4206816) Show SMILES Cc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2cccnc2)cc1 Show InChI InChI=1S/C22H22N8OS/c1-14-4-6-16(7-5-14)25-22(31)30-11-9-29(10-12-30)18-17-20(28-21(23)27-18)32-19(26-17)15-3-2-8-24-13-15/h2-8,13H,9-12H2,1H3,(H,25,31)(H2,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50042924 (CHEMBL1229535) Show SMILES CC(=O)\N=c1\[nH]c(C)c(s1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO Show InChI InChI=1S/C14H16ClN3O4S2/c1-8-13(23-14(17-8)18-9(2)20)10-3-4-11(15)12(7-10)24(21,22)16-5-6-19/h3-4,7,16,19H,5-6H2,1-2H3,(H,17,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01467 BindingDB Entry DOI: 10.7270/Q24Q801K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200103 (CHEMBL3948449) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)n2cccn2)ccn1 Show InChI InChI=1S/C25H24ClN7O3S/c1-4-19-12-17(8-10-27-19)15-28-20-14-23(26)31-33-24(16(2)30-25(20)33)18-6-7-21(36-3)22(13-18)37(34,35)32-11-5-9-29-32/h5-14,28H,4,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200096 (CHEMBL3893537) Show SMILES COc1ccc(cc1S(=O)(=O)NCC=C)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C21H25ClN6O4S/c1-5-8-25-33(30,31)18-11-15(6-7-17(18)32-4)20-13(2)26-21-16(12-19(22)27-28(20)21)24-10-9-23-14(3)29/h5-7,11-12,24-25H,1,8-10H2,2-4H3,(H,23,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50579668 (CHEMBL5091438) Show SMILES C[C@@H](C1CC1)N1Cc2cc-3cc(c2C1=O)S(=O)(=O)NCCOCCNC(=O)c1cccc(Nc2nc(C)c-3s2)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PI4KB (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00434 BindingDB Entry DOI: 10.7270/Q24Q7ZVJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457866 (CHEMBL4207928) Show SMILES COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3scnc23)c(C)n1 |r| Show InChI InChI=1S/C18H22N8O2S/c1-10-8-25(18(27)22-12-4-5-13(28-3)21-11(12)2)6-7-26(10)15-14-16(29-9-20-14)24-17(19)23-15/h4-5,9-10H,6-8H2,1-3H3,(H,22,27)(H2,19,23,24)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199892 (CHEMBL3889874) Show SMILES COc1ccc(cc1S(=O)(=O)NCCO)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C20H25ClN6O5S/c1-12-19(14-4-5-16(32-3)17(10-14)33(30,31)24-8-9-28)27-20(25-12)15(11-18(21)26-27)23-7-6-22-13(2)29/h4-5,10-11,23-24,28H,6-9H2,1-3H3,(H,22,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50005004 (CHEMBL2397309) Show SMILES CO[C@H]1CC[C@H](CC1)C(=O)Nc1nc(C)c(s1)-c1ccc(N)nc1 |r,wU:5.8,2.1,(18.48,-29.12,;17.85,-27.71,;16.32,-27.55,;15.42,-28.8,;13.89,-28.64,;13.26,-27.23,;14.16,-25.98,;15.69,-26.14,;11.73,-27.08,;10.83,-28.32,;11.1,-25.67,;9.57,-25.52,;8.79,-24.19,;7.29,-24.51,;6.14,-23.48,;7.13,-26.04,;8.54,-26.66,;5.8,-26.81,;4.46,-26.05,;3.13,-26.82,;3.13,-28.36,;1.8,-29.13,;4.46,-29.13,;5.8,-28.36,)| Show InChI InChI=1S/C17H22N4O2S/c1-10-15(12-5-8-14(18)19-9-12)24-17(20-10)21-16(22)11-3-6-13(23-2)7-4-11/h5,8-9,11,13H,3-4,6-7H2,1-2H3,(H2,18,19)(H,20,21,22)/t11-,13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd. Curated by ChEMBL					Assay Description Inhibition of PI4K3beta (unknown origin)				Bioorg Med Chem Lett 23: 3841-7 (2013) Article DOI: 10.1016/j.bmcl.2013.04.077 BindingDB Entry DOI: 10.7270/Q2BG2QCX
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457862 (CHEMBL4204100) Show SMILES COc1ccc(NC(=O)N2CCN(C(C)C2)c2nc(N)nc3scnc23)cc1 Show InChI InChI=1S/C18H21N7O2S/c1-11-9-24(18(26)21-12-3-5-13(27-2)6-4-12)7-8-25(11)15-14-16(28-10-20-14)23-17(19)22-15/h3-6,10-11H,7-9H2,1-2H3,(H,21,26)(H2,19,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50199996 (CHEMBL3915835) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)nc2c(NCc3ccncc3)cc(Cl)nn12 Show InChI InChI=1S/C21H21ClN6O2S/c1-14-20(16-5-4-6-17(11-16)31(29,30)27(2)3)28-21(25-14)18(12-19(22)26-28)24-13-15-7-9-23-10-8-15/h4-12,24H,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair

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